scholarly journals 14-3-3γ regulates cell viability and milk fat synthesis in lipopolysaccharide-induced dairy cow mammary epithelial cells

2016 ◽  
Vol 11 (4) ◽  
pp. 1279-1287 ◽  
Author(s):  
LIXIN LIU ◽  
LI ZHANG ◽  
YE LIN ◽  
YANJIE BIAN ◽  
XUEJUN GAO ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Cell Viability ◽  
Dairy Cow ◽  
Milk Fat ◽  
Mammary Epithelial Cells ◽  
Mammary Epithelial ◽  
Fat Synthesis ◽  
Milk Fat Synthesis

scholarly journals Function of SREBP1 in the Milk Fat Synthesis of Dairy Cow Mammary Epithelial Cells

2014 ◽  
Vol 15 (9) ◽  
pp. 16998-17013 ◽  
Author(s):  
Nan Li ◽  
Feng Zhao ◽  
Chenjie Wei ◽  
Mengyao Liang ◽  
Na Zhang ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Dairy Cow ◽  
Milk Fat ◽  
Mammary Epithelial Cells ◽  
Mammary Epithelial ◽  
Fat Synthesis ◽  
Milk Fat Synthesis

MicroRNA-432 inhibits milk fat synthesis by targeting SCD and LPL in ovine mammary epithelial cells

2021 ◽  
Author(s):  
Zhiyun Hao ◽  
Yuzhu Luo ◽  
Jiqing Wang ◽  
Jon Hickford ◽  
Huitong Zhou ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Epithelial Cells ◽  
Milk Production ◽  
Milk Fat ◽  
Mammary Epithelial Cells ◽  
Mammary Epithelial ◽  
Differentially Expressed ◽  
Differentially Expressed Mirnas ◽  
Fat Synthesis ◽  
Milk Fat Synthesis

In our previous studies, microRNA-432 (miR-432) was found to be one of differentially expressed miRNAs in ovine mammary gland between the two breeds of lactating sheep with different milk production...

Effect of INSIG1 on the milk fat synthesis of buffalo mammary epithelial cells

2020 ◽  
Vol 87 (3) ◽  
pp. 349-355
Author(s):  
Xinyang Fan ◽  
Lihua Qiu ◽  
Xiaohong Teng ◽  
Yongyun Zhang ◽  
Yongwang Miao
Keyword(s):  
Epithelial Cells ◽  
Milk Fat ◽  
Mammary Epithelial Cells ◽  
Strong Support ◽  
Mammary Epithelial ◽  
Mammary Tissue ◽  
Peak Period ◽  
Fat Synthesis ◽  
Milk Fat Synthesis

AbstractWe hypothesized that insulin-induced gene 1 (INSIG1) affects milk fat synthesis in buffalo. For this reason, the protein abundance of INSIG1 in the mammary tissue of buffalo during the peak period of lactation and dry-off period was evaluated. The results showed that the expression of INSIG1 at the peak of lactation was lower than that in the dry-off period. To explore the role of INSIG1 in milk fat synthesis, the buffalo mammary epithelial cells (BMECs) were isolated and purified from buffalo mammary tissue, and INSIG1 gene were overexpressed and knocked down by constructing the recombinant lentivirus vector of INSIG1 gene and transfecting into BMECs. Results revealed that INSIG1 overexpression decreased the expression of INSIG2, SREBP, PPARG, SCD, GPAM, DGAT2 and AGPAT6, which led to reduction of triglycerides (TAG) content in the cell. In contrast, knockdown of INSIG1 had a positive effect on mRNA expression of the above genes. Overall, the data provide strong support for a key role of INSIG1 in the regulation of milk fat synthesis in BMECs.

CRTC2 Is a Key Mediator of Amino Acid-Induced Milk Fat Synthesis in Mammary Epithelial Cells

2019 ◽  
Vol 67 (37) ◽  
pp. 10513-10520 ◽  
Author(s):  
Ping Li ◽  
Chengjian Zhou ◽  
Xueying Li ◽  
Mengmeng Yu ◽  
Meng Li ◽  
...  
Keyword(s):  
Amino Acid ◽  
Epithelial Cells ◽  
Milk Fat ◽  
Mammary Epithelial Cells ◽  
Mammary Epithelial ◽  
Fat Synthesis ◽  
Milk Fat Synthesis
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