scholarly journals Late-onset prosthetic valve endocarditis caused by nontoxigenic Corynebacterium diphtheriae

2015 ◽  
Vol 9 (08) ◽  
pp. 905-909 ◽  
Author(s):  
Malak M EL-Hazmi
Keyword(s):  
Saudi Arabia ◽  
Prosthetic Valve ◽  
Late Onset ◽  
Prosthetic Valve Endocarditis ◽  
Developed Countries ◽  
Corynebacterium Diphtheriae ◽  
High Morbidity ◽  
Immunization Programs ◽  
Kingdom Of Saudi Arabia ◽  
Atypical Case

In developed countries, Corynebacterium diphtheriae infection is rare due to efficient immunization programs. However, cases of nontoxigenic strains of C. diphtheriae infections, including endocarditis, have been reported recently. Although the incidence remains low, these infections are associated with high morbidity and mortality. This report describes the first and atypical case of bacteremia and endocarditis caused by nontoxigenic C. diphtheriae var. gravis after introduction of immunization in the Kingdom of Saudi Arabia (KSA).

scholarly journals Mechanical valve endocarditis caused by Gemella morbillorum

2007 ◽  
Vol 56 (12) ◽  
pp. 1689-1691 ◽  
Author(s):  
Ghanem Al-Hujailan ◽  
Philippe Lagacé-Wiens
Keyword(s):  
Clinical Experience ◽  
Prosthetic Valve ◽  
Late Onset ◽  
Bacterial Pathogens ◽  
Relevant Literature ◽  
Prosthetic Valve Endocarditis ◽  
Mechanical Valve ◽  
Coagulase Negative Staphylococcus ◽  
Diagnostic Dilemma ◽  
Pathogen Spectrum

As the usual pathogen spectrum of a late-onset (>12 month post-operatively) prosthetic valve endocarditis is similar to normal valve endocarditis, with the exception of coagulase-negative staphylococcus, a prosthetic valve endocarditis caused by unusual bacterial pathogens represents a therapeutic and diagnostic dilemma. The lack of well established criteria or clinical experience for the management of such infections makes therapy and prognosis difficult to determine. A case of successfully treated Gemella morbillorum prosthetic valve endocarditis and a review of the relevant literature are presented.

The Impact of Hospital-Acquired Infections on the Microbial Etiology and Prognosis of Late-Onset Prosthetic Valve Endocarditis

CHEST Journal ◽  
2005 ◽  
Vol 128 (2) ◽  
pp. 764-771 ◽  
Author(s):  
Pablo Rivas ◽  
Julio Alonso ◽  
Javier Moya ◽  
Miguel de Górgolas ◽  
Jorge Martinell ◽  
...  
Keyword(s):  
Prosthetic Valve ◽  
Late Onset ◽  
Prosthetic Valve Endocarditis ◽  
Hospital Acquired Infections ◽  
Microbial Etiology ◽  
Hospital Acquired ◽  
The Impact

Methodology for BIM implementation in the Kingdom of Saudi Arabia

2018 ◽  
pp. 01-20
Author(s):  
Ashraf Elhendawi ◽  
◽  
Andrew Smith ◽  
Emad Elbeltagi ◽  
◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Developed Countries ◽  
Information Modeling ◽  
Key Factors ◽  
Structured Interviews ◽  
Kingdom Of Saudi Arabia ◽  
Factors Affecting ◽  
Raising Awareness ◽  
Building Information ◽  
Aec Industry

Purpose – The Architecture, Engineering, and Construction (AEC) industry is considered the most effective contributor to development in the Kingdom of Saudi Arabia (KSA). However, the AEC industry is facing myriad challenges due to the vast construction development required for the KSA 2030 vision. Developed countries are using Building Information Modeling (BIM) to mitigate these challenges and reap the benefits of implementing BIM to improve the performance of the AEC industry profoundly. However, BIM is currently rarely used in the KSA. This study aims to develop a methodology to implement BIM in the KSA by exploring stakeholders’ perception of factors affecting the implementation. Design/methodology/approach – BIM users and non-users were surveyed by means of a questionnaire and structured interviews. The proposed methodology was validated through a further survey and structured interviews with BIM experts. Findings – This study proposes a six-step methodology to implement BIM namely; raising awareness; perceived benefits; AEC industry readiness, and organizations’ capability; identifying the barriers; removing the barriers; and defining the key factors influencing the implementation. Practical implications – The proposed methodology is expected to assist project participants in KSA to implement BIM to solve current AEC industry issues, improve projects’ performance and reap the benefits of implementing BIM. Originality/value – This study makes a crucial and novel contribution by providing a new methodology to implement BIM in KSA that motivates decision-makers and project players to adopt and implement BIM in their projects. It paves the way to develop BIM guidance and strategies.

scholarly journals Type 1 Diabetes Mellitus in Saudi Arabia: A Soaring Epidemic

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Asirvatham Alwin Robert ◽  
Abdulrahman Al-Dawish ◽  
Muhammad Mujammami ◽  
Mohamed Abdulaziz Al Dawish
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Saudi Arabia ◽  
Type 1 Diabetes Mellitus ◽  
Developed Countries ◽  
Kingdom Of Saudi Arabia ◽  
Unique Challenge ◽  
The World ◽  
The Developed Countries

Type 1 diabetes mellitus (T1DM) is quite prevalent in the world, with a proportion of 1 in every 300 persons and steadily rising frequency of incidence of about 3% every year. More alarmingly, the incidence of T1DM among infants is also increasing, with children as young as 6 months succumbing to it, instead of that at a rather established vulnerable age of around seven and near puberty, when the hormones antagonize the action of insulin. These reports pose a unique challenge of developing efficient T1DM management system for the young children. The Kingdom of Saudi Arabia (KSA) is the largest country in the Middle East that occupies approximately four-fifths of the Arabian Peninsula supporting a population of more than 33.3 million people, of whom 26% are under the age of 14 years. As per the Diabetes Atlas (8th edition), 35,000 children and adolescents in Saudi Arabia suffer from T1DM, which makes Saudi Arabia rank the 8th in terms of numbers of TIDM patients and 4th country in the world in terms of the incidence rate (33.5 per 100,000 individuals) of TIDM. However, in comparison with that in the developed countries, the number of research interventions on the prevalence, incidence, and the sociodemographic aspects of T1DM is woefully inadequate. In this review we discuss different aspects of T1DM in Saudi Arabia drawing on the published literature currently available.

scholarly journals Graduate Employability in the Kingdom of Saudi Arabia: A future research Agenda

2019 ◽  
Vol 8 (3S2) ◽  
pp. 812-817
Keyword(s):  
Saudi Arabia ◽  
Developed Countries ◽  
School To Work ◽  
Research Trends ◽  
Smooth Transition ◽  
Future Research ◽  
Policy Debate ◽  
Kingdom Of Saudi Arabia ◽  
Future Research Agenda ◽  
Education Process

In recent decades, a growing body of literature has emerged to illustrate the strong pressure on education institutions to prepare graduates for the world of work. This challenge has intensified since the expansion of higher education process that reframed the policy debate and placed the smooth transition from school-to-work and the employability of graduates at the forefront of education policy. In this scenario it is imperative to analyze the research trends in this area of research. The present study examined the research articles published in this area till 2018. The data was collected using the Scopus database to analyze the research trends in this area. The study findings have clearly highlighted that majority of the research in the field of employability is conducted in developed countries and this area of study is under explored in Kingdom of Saudi Arabia. The findings also showed that the research related to the factors contributing towards Saudi graduates’ employability is one area which needs to be studied.

scholarly journals Late-onset prosthetic valve endocarditis caused by Mycoplasma hominis, diagnosed using broad-range bacterial PCR

2012 ◽  
Vol 61 (2) ◽  
pp. 300-301 ◽  
Author(s):  
H. A. Jamil ◽  
J. A. T. Sandoe ◽  
D. Gascoyne-Binzi ◽  
V. J. Chalker ◽  
A. D. Simms ◽  
...  
Keyword(s):  
Prosthetic Valve ◽  
Late Onset ◽  
Prosthetic Valve Endocarditis ◽  
Mycoplasma Hominis

scholarly journals Small and Medium enterprises in the Kingdom of Saudi Arabia between Reality and Hope, according to 2030 Vision: An Empirical Study: المشروعات الصغيرة والمتوسطة في المملكة العربية السعودية بين الواقع والمأمول، في ضوء رؤية 2030م: دراسة تطبيقية

2020 ◽  
Vol 4 (9) ◽  
Author(s):  
Ali Nageh Ali Mansour
Keyword(s):  
Saudi Arabia ◽  
Small And Medium Enterprises ◽  
Developed Countries ◽  
Lessons Learned ◽  
Comparative Approach ◽  
Small Enterprises ◽  
Kingdom Of Saudi Arabia ◽  
Vision 2030 ◽  
Medium Enterprises

The aim of this research is to analyze the most important obstacles and challenges facing small and medium enterprises within the Kingdom of Saudi Arabia in the light of international experiences, and to analyze and evaluate the role of the Small and Medium Enterprises Authority “Monshaat” in facing challenges facing small and medium enterprises inside the Kingdom; and to know the true reality of small and medium enterprises in The Kingdom of Saudi Arabia as well as reaching the hoped- for according to 2030 Vision, which aims to reform the Saudi economy and continue its growth and end its dependence on oil as a main source of income. The researcher analyzed the current situation of small and medium enterprises in the Kingdom of Saudi Arabia and compared them to the global situation through studying and analyzing leading global experiences and identifying aspects of benefiting from them. The research relied on the deductive approach, which is the approach that begins with the theory and ends with its applicability to the ground. The research also used the descriptive approach to describe the topic of the research, its importance, goals, and the most important studies that dealt with the role of small projects in economic development both inside and outside the Kingdom. The comparative approach to making comparisons from and reviewing the experiences of other countries and extracting lessons learned from them. It also relied on the standard method, which aims to measure economic phenomena and variables. This research found that there are many difficulties that hinder these projects from achieving the goals of the vision, including obtaining financing, as the rate of financing small enterprises does not exceed 5% of the total financing in the Kingdom. It is a small percentage compared to international rates. The result is a decrease in the contribution of small and medium enterprises to the gross domestic product if they do not exceed 20% and 53% of jobs in the Kingdom of Saudi Arabia. The Kingdom's Vision 2030 aims to raise this percentage to 35% by 2030, and this percentage reaches about 70% in developed countries, The number of small enterprises reached 12% of the number of projects for the year 2018, and it contributes about 29% of the total revenues of enterprises, according to the data for the second quarter of 2016. The researcher recommends decision- makers and those who are interested in business leaders inside the Kingdom to overcome the challenges facing small projects and entrepreneurs by providing them with adequate support, whether material or logistical support or both together, and work to establish a financial fund to finance small and medium projects with low benefits, and share the fund with proportions Certain of the annual profits during a specific period, depending on the value of the loan, the size of the facility, the value of revenue, the idea of ​​the project, and converting the Public Authority for Small and Medium Enterprises in the Kingdom into an independent ministry whose mission is to take great care of small projects and For medium.

Effects of Tigecycline, Linezolid and Vancomycin on Biofilms of Viridans Streptococci Isolates from Patients with Endocarditis

2007 ◽  
Vol 30 (9) ◽  
pp. 798-804 ◽  
Author(s):  
E. Presterl ◽  
A. Lassnigg ◽  
M. Eder ◽  
S. Reichmann ◽  
A. M. Hirschl ◽  
...  
Keyword(s):  
Optical Density ◽  
Prosthetic Valve ◽  
Density Ratio ◽  
Prosthetic Valve Endocarditis ◽  
Microtiter Plate ◽  
High Morbidity ◽  
Viridans Streptococci ◽  
Biofilm Thickness ◽  
Minimal Inhibitory Concentrations ◽  
Optical Density Ratio

Background Endocarditis, and prosthetic valve endocarditis in particular, is a serious disease with high morbidity and mortality. We investigate the effects of tigecycline, linezolid and vancomycin on biofilms of viridans group streptococci (VGS) isolated from patients with definite native or prosthetic valve endocarditis. Methods and Results Ten of 20 VGS blood stream isolates from patients with endocarditis formed biofilms in the microtiter plate biofilm model. The minimal inhibitory concentrations (MIC) for tigecycline, linezolid and vancomycin were determined using the microdilution broth method. Biofilms were grown for 24 hours and were incubated with tigecycline, linezolid and vancomycin at increasing concentrations from 1-128x MIC of the isolate being tested. Biofilm thickness was quantified by measuring the optical density (OD) after dyeing it with crystal violet. The incubation of the biofilms with tigecycline, linezolid or vancomycin resulted in a significant reduction of OD compared to the control biofilm without antibiotic (p<0.05). The optical density ratio (Odr) decreased significantly at 2x MIC for tigecycline, and at 8x MIC for linezolid and vancomycin (p<0.05). Although biofilms persisted even at the highest antibiotic concentrations of 128x MIC, bacterial growth was eradicated starting at concentrations of 16x MIC for vancomycin and of 32x MIC for linezolid, but not for tigecycline, up to a concentration of 128x MIC. Conclusions In the present study on viridans streptococci isolated from patients with endocarditis, tigecycline and linezolid reduced the density of the biofilms as effectively as vancomycin. However, linezolid and vancomycin were bactericidal at higher concentrations. Linezolid and vancomycin at very high doses may be useful in the treatment of biofilm-associated diseases caused by VGS infections.

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