Viral clearance and inflammatory response patterns in adults hospitalized for pandemic 2009 influenza A(H1N1) virus pneumonia

2011 ◽  
Vol 16 (2) ◽  
pp. 237-247 ◽  
Author(s):  
Nelson Lee ◽  
Paul KS Chan ◽  
Chun Kwok Wong ◽  
Ka-Tak Wong ◽  
Kin-Wing Choi ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Influenza A ◽  
H1n1 Virus ◽  
Viral Clearance ◽  
Response Patterns ◽  
Influenza A H1n1 ◽  
Virus Pneumonia

scholarly journals The impact of altitude on hospitalization and hospital mortality from pandemic 2009 influenza A (H1N1) virus pneumonia in Mexico

2013 ◽  
Vol 55 (1) ◽  
pp. 92-95 ◽  
Author(s):  
Rogelio Pérez-Padilla ◽  
Cecilia García-Sancho ◽  
Rosario Fernández ◽  
Francisco Franco-Marina ◽  
Hugo López-Gatell ◽  
...  
Keyword(s):  
Hospital Mortality ◽  
Influenza A ◽  
H1n1 Virus ◽  
Influenza A H1n1 ◽  
Virus Pneumonia ◽  
The Impact

A Case of Novel Influenza A (H1N1) Virus Pneumonia Complicated Pnemomediastinum and Subcutenous Emphysema

2011 ◽  
Vol 70 (2) ◽  
pp. 155
Author(s):  
Yu Jin Kim ◽  
Sung-Young Kyung ◽  
Jung-Woong Park ◽  
Sung Hwan Jeong ◽  
Yiel-Hea Seo ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Influenza A H1n1 ◽  
Virus Pneumonia ◽  
Novel Influenza A

scholarly journals Comparative Analysis of Early-Stage Clinical Features Between COVID-19 and Influenza A H1N1 Virus Pneumonia

2020 ◽  
Vol 8 ◽  
Author(s):  
Changxing Shen ◽  
Min Tan ◽  
Xiaolian Song ◽  
Guoliang Zhang ◽  
Jiren Liang ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Clinical Features ◽  
Influenza A ◽  
H1n1 Virus ◽  
Early Stage ◽  
Influenza A H1n1 ◽  
Virus Pneumonia

An unusual cause of fever in a neonate: Influenza A (H1N1) virus pneumonia

2010 ◽  
Vol 45 (7) ◽  
pp. 734-736 ◽  
Author(s):  
Ahmet Sert ◽  
Abdullah Yazar ◽  
Dursun Odabas ◽  
Hüseyin Bilgin
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Influenza A H1n1 ◽  
Virus Pneumonia

scholarly journals Cytokine levels in bronchoalveolar lavage and serum in 3 patients with 2009 Influenza A(H1N1)v severe pneumonia

2011 ◽  
Vol 5 (07) ◽  
pp. 540-543 ◽  
Author(s):  
Angel Estella
Keyword(s):  
Inflammatory Response ◽  
Bronchoalveolar Lavage ◽  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Interleukin 1 ◽  
Severe Pneumonia ◽  
Enzyme Linked Immunosorbent Assay ◽  
Necrosis Factor Alpha ◽  
Influenza A H1n1

Introduction: Pandemic Influenza A (H1N1)v pneumonia has led to a notable increase of admissions to intensive care units. A cytokine-mediated inflammatory response has been well documented in pneumonia and acute respiratory distress syndrome. However, few studies have focused on the role of these inflammatory mediators in infections caused by the Influenza A (H1N1)v. In this study, we assess the inflammatory response mediated by cytokines at the local and systemic levels in three cases of severe pneumonia caused by Influenza A (H1N1) virus. Methodology: Serum and bronchoalveolar lavage samples were obtained from three mechanically ventilated patients diagnosed with Influenza A (H1N1) virus pneumonia by bronchoscopic bronchoalveolar lavage.  Levels of interleukin 6 (IL-6), interleukin 8 (IL-8), tumour necrosis factor alpha (TNFα) and interleukin 1 beta (IL-1ß) were meassured in these samples by enzyme-linked immunosorbent assay (ELISA). Results: High levels of C Reactive Protein, Procalcitonin below 1 ng/ml and absence of leukocytosis were common findings in all patients. TNF α and IL-1ß were not detected in the serum. IL-6 levels in serum were (94, pg/ml, 77 pg/ml and 84 pg/ml) respectively in the three patients, while IL-8 levels were (30,2 pg/ml, 128 pg/ml and 40,5 pg/ml). In the BAL samples, only one of the analysed cytokines, IL-1ß was present at detectable levels in two patients (21 pg/ml and 11 pg/ml respectively). Conclusions: Our results support previous findings which suggest that high levels of IL-6 and IL-8 in serum somehow participate in the inflammatory response in severe cases of pandemic influenza pneumonia.

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