scholarly journals Chemical constituents of Dicentra spectabilis and their anti-inflammation effect

2018 ◽  
Vol 61 (1) ◽  
pp. 39-46 ◽  
Author(s):  
A Hyeon Kim ◽  
Ji Hun Jang ◽  
Kyeong Wan Woo ◽  
Jong Eel Park ◽  
Ki Ho Lee ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Anti Inflammation ◽  
Dicentra Spectabilis

scholarly journals A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine

2019 ◽  
Vol 20 (6) ◽  
pp. 1463 ◽  
Author(s):  
Zhenzhen Guo ◽  
Yanmei Lou ◽  
Muyan Kong ◽  
Qing Luo ◽  
Zhongqiu Liu ◽  
...  
Keyword(s):  
Personalized Medicine ◽  
Chemical Constituents ◽  
Herbal Medicines ◽  
Major Type ◽  
Clinical Practices ◽  
Antitumor Activities ◽  
Astragali Radix ◽  
Pharmacological Studies ◽  
Anti Inflammation

Astragali radix (AR) is one of the most widely used traditional Chinese herbal medicines. Modern pharmacological studies and clinical practices indicate that AR possesses various biological functions, including potent immunomodulation, antioxidant, anti-inflammation and antitumor activities. To date, more than 200 chemical constituents have been isolated and identified from AR. Among them, isoflavonoids, saponins and polysaccharides are the three main types of beneficial compounds responsible for its pharmacological activities and therapeutic efficacy. After ingestion of AR, the metabolism and biotransformation of the bioactive compounds were extensive in vivo. The isoflavonoids and saponins and their metabolites are the major type of constituents absorbed in plasma. The bioavailability barrier (BB), which is mainly composed of efflux transporters and conjugating enzymes, is expected to have a significant impact on the bioavailability of AR. This review summarizes studies on the phytochemistry, pharmacology and pharmacokinetics on AR. Additionally, the use of AR as a personalized medicine based on the BB is also discussed, which may provide beneficial information to achieve a better and more accurate therapeutic response of AR in clinical practice.

scholarly journals Health Promoting Effects of Ziziphus mauritiana : An Overview

2020 ◽  
Vol 11 (1) ◽  
pp. 1067-1072
Author(s):  
Akassh M ◽  
Fathima T ◽  
Mruthunjaya K
Keyword(s):  
Hair Growth ◽  
Web Of Science ◽  
Indian Subcontinent ◽  
Chemical Constituents ◽  
Ziziphus Mauritiana ◽  
Review Of The Literature ◽  
The Family ◽  
Health Promoting ◽  
Antioxidant Effects ◽  
Anti Inflammation

Natural products are the main source for an alternative system of medicine. Ziziphus mauritiana, commonly known as jujubes, belongs to the family Rhamnaceae and is majorly found in the Indian subcontinent. They are traditionally used to treat chronic bronchitis, insomnia, diabetes, diarrhoea, abscesses, wounds, liver diseases, fever, sleeplessness, constipation, urinary diseases, and abdominal pains. Over the course of many years, various parts of Ziziphus mauritiana has been found to possess hair growth stimulating, anti-platelet aggregating, anti-inflammation, wound-healing, anti-obesity, antibacterial, and antioxidant effects. Various peer-reviewed research articles were collected from SCOPUS, PubMed, Google, Research Gate, and Web of Science databases. A total of 26 papers were selected based on their relevance. Acetyljujuboside B, Mauritine A, and Jujuboside A are some of the numerous chemical constituents present in Ziziphus mauritiana. The present review is an effort to provide a comprehensive review of the literature on the health-promoting effects of Ziziphus mauritiana.

Chemical constituents of Ligusticum chuanxiong and their anti-inflammation and hepatoprotective activities

2020 ◽  
Vol 101 ◽  
pp. 104016 ◽  
Author(s):  
Xiang Yuan ◽  
Bing Han ◽  
Zi-Ming Feng ◽  
Jian-Shuang Jiang ◽  
Ya-Nan Yang ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Ligusticum Chuanxiong ◽  
Anti Inflammation

scholarly journals Fritillariae Thunbergii Bulbus: Traditional Uses, Phytochemistry, Pharmacodynamics, Pharmacokinetics and Toxicity

2019 ◽  
Vol 20 (7) ◽  
pp. 1667 ◽  
Author(s):  
Hong Li ◽  
Andrew Hung ◽  
Mingdi Li ◽  
Angela Yang
Keyword(s):  
Chemical Constituents ◽  
Blood Rheology ◽  
Chemical Compounds ◽  
Pharmacological Effects ◽  
Historical Records ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Anti Cancer ◽  
Pharmacological Studies ◽  
Anti Inflammation

Fritillariae Thunbergii Bulbus (FTB) has been widely used as an antitussive herb for thousands of years in China. However, FTB’s traditional uses, chemical compounds and pharmacological activities have not been systematically reviewed. This study aimed to review its traditional uses, phytochemistry, pharmacodynamics, pharmacokinetics and toxicity. We searched the Encyclopedia of Traditional Chinese Medicine to explore the historical records which indicate that it acts to clear heat, resolve phlegm, relieve cough, remove toxicity and disperse abscesses and nodules. We searched 11 databases to identify potential phytochemical or pharmacological studies. Characteristics of its chemical constituents, pharmacological effects, pharmacokinetic and toxicity were descriptively summarized. A total of 9706 studies were identified and 83 of them were included. As a result, 134 chemical constituents were identified, including 26 alkaloids, 29 compounds found in essential oils, 13 diterpenoids, two carbohydrates, two sterols, 18 amino acids, six nucleosides, four nucleobases, four fatty acids, three lignans, and 27 elements. Thirteen pharmacological effects of FTB were identified, including anti-cancer, tracheobronchial relaxation, antitussive, expectorant, anti-muscarinic, anti-inflammation, anti-thyroid, regulation of blood rheology, antiulcer, anti-diarrhea, pain suppression, antioxidation and neuroprotection. These pharmacological activities may be mainly attributed to the alkaloids in FTB. Further phytochemical, pharmacological and network pharmacological studies are recommended.

scholarly journals RED GINGER (Zingiber officinale var. rubrum): ITS CHEMICAL CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES AND SAFETY

2019 ◽  
Vol 8 (1) ◽  
pp. 23-29
Author(s):  
Rini Daud Supu ◽  
Ajeng Diantini ◽  
Jutti Levita
Keyword(s):  
Chemical Constituents ◽  
Zingiber Officinale ◽  
The Other ◽  
Herbal Supplements ◽  
Pharmacological Activities ◽  
Adverse Side Effects ◽  
Beneficial Effects ◽  
Medicinal Properties ◽  
Red Ginger ◽  
Anti Inflammation

Ginger (Zingiber officinale) which belongs to the Zingiberaceae family, was first cultivated in Asia (Indonesia and Malaysia). This plant is one of the most commonly used herbal supplements taken by many patients to treat various conditions. Z.officinale has three varieties based on its size, colors of rhizome and chemical constituents i.e. .Z. officinale var. officinale (big white ginger or giant ginger, badak or gajah), Z. officinale var. amarum (small white ginger, emprit), and Z. officinale var. rubrum (small red ginger, merah or beureum). These three varieties may partly be deferred from their essential oil contents and are used for different purposes. The essential oils contained in Z. officinale var. rubrum are higher than the other types of ginger, which makes stronger in its pungency smell and taste. There are many studies that confirm beneficial effects of red ginger against the symptoms of diseases, i.e. anti-inflammation, antioxidant, antiemetic, antibacterial and antidiabetics. Z.officinale var. rubrum is considered to be a safe herbal medicine with only few and insignificant adverse/side effects. Although the medicinal properties of red ginger have been known, further trials in humans are required to determine the efficacy of red ginger (or one or more of its constituents) and to establish what, if any, adverse effects are observed.

scholarly journals Composition and Anti-inflammatory Activity of Essential Oil of Jatropha Curcas

2017 ◽  
Vol 12 (3) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Tolulope E. Adeosun ◽  
Isiaka A. Ogunwande ◽  
Opeyemi N. Avoseh ◽  
Ismail P. Raji ◽  
Oladipupo A. Lawal
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Jatropha Curcas ◽  
Chemical Constituents ◽  
Significant Inhibition ◽  
Inflammatory Activity ◽  
Gas Chromatography Mass Spectrometry ◽  
Leaf Oil ◽  
Anti Inflammatory ◽  
Anti Inflammation

The chemical constituents and anti-inflammatory activity of the essential oil from the leaf of Jatropha curcas L (Euphorbiaceae) collected from Nigeria are reported. The analysis of the chemical constituents of the essential oil was achieved by using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). All constituents of the essential oil, namely neophytadiene (35.8%), phytol (23.1%), trans-pinane (12.7%), 6,10,14-trimethyl-2-pentadecanone (12.3%) and citronellyl propanoate (11.2%), were present in significant amounts. The anti-inflammatory activity of the leaf oil was determined on Wistar rats using egg-albumin as phlogistic agent; significant inhibition ( P< 0.05) was shown at a dose of 2%, v/v. Percentage inhibition of the anti-inflammation increased steadily to 76.6% in the 4th hour.

Electron microscopic studies on ultrathin frozen sections of lactating mouse mammary gland

1978 ◽  
Vol 36 (2) ◽  
pp. 46-47
Author(s):  
Jan Zarzycki ◽  
Joseph Szroeder
Keyword(s):  
Mammary Gland ◽  
Protein Denaturation ◽  
Chemical Constituents ◽  
Freeze Substitution ◽  
Electron Microscopic Examination ◽  
Mouse Mammary Gland ◽  
Electron Microscopic ◽  
Preparation Methods ◽  
Microscopic Studies ◽  
Ultrathin Frozen Sections

The mammary gland ultrastructure in various functional states is the object of our investigations. The material prepared for electron microscopic examination by the conventional chemical methods has several limitations, the most important are the protein denaturation processes and the loss of large amounts of chemical constituents from the cells. In relevance to this,one can't be sure about a degree the observed images are adequate to the realy ultrastructure of a living cell. To avoid the disadvantages of the chemical preparation methods,some autors worked out alternative physical methods based on tissue freezing / freeze-drying, freeze-substitution, freeze-eatching techniqs/; actually the technique of cryoultraraicrotomy,i,e.cutting ultrathin sections from deep frozen specimens is assented as a complete alternative method. According to the limitations of the routine plastic embbeding methods we were interested to analize the mammary gland ultrastructure during lactation by the cryoultramicrotomy method.

Sem and X-Ray Analysis of Renal and Biliary Calculi

1976 ◽  
Vol 34 ◽  
pp. 306-307
Author(s):  
R. J. Narconis ◽  
G. L. Johnson
Keyword(s):  
Chemical Constituents ◽  
Natural State ◽  
X Ray Diffraction ◽  
Chemical Methods ◽  
X Ray ◽  
Additional Dimension ◽  
Biliary Calculi ◽  
Calculus Formation ◽  
Scanning Electron

Analysis of the constituents of renal and biliary calculi may be of help in the management of patients with calculous disease. Several methods of analysis are available for identifying these constituents. Most common are chemical methods, optical crystallography, x-ray diffraction, and infrared spectroscopy. The application of a SEM with x-ray analysis capabilities should be considered as an additional alternative.A scanning electron microscope equipped with an x-ray “mapping” attachment offers an additional dimension in its ability to locate elemental constituents geographically, and thus, provide a clue in determination of possible metabolic etiology in calculus formation. The ability of this method to give an undisturbed view of adjacent layers of elements in their natural state is of advantage in determining the sequence of formation of subsequent layers of chemical constituents.

Immunopharmacological potential of the leading chemical constituents from Leuzea carthamoides

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
J Harmatha ◽  
E Kmoníčková ◽  
Z Zídek
Keyword(s):  
Chemical Constituents
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