scholarly journals Age at onset and response to antiepileptic drugs in patients with various subtypes of idiopathic generalized epilepsy - preliminary investigation for the prevention of epilepsy

2018 ◽  
Vol 10 (1) ◽  
pp. 95-106
Author(s):  
Shunsuke Takagi ◽  
Tatsuya Yamamoto ◽  
Koichiro Hara ◽  
Kazuhiro Muramatsu ◽  
Masako Watanabe ◽  
...  
Keyword(s):  
Antiepileptic Drugs ◽  
Preliminary Investigation ◽  
Age At Onset ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals The genetic variant “C588T” of GABARG2 is linked to childhood idiopathic generalized epilepsy and resistance to antiepileptic drugs

Seizure ◽  
2018 ◽  
Vol 60 ◽  
pp. 39-43 ◽  
Author(s):  
Soheir S. Abou El Ella ◽  
Maha Atef Tawfik ◽  
Wafaa Moustafa M. Abo El Fotoh ◽  
Omar Ahmed M. Soliman
Keyword(s):  
Antiepileptic Drugs ◽  
Genetic Variant ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

Idiopathic generalized epilepsy and choice of antiepileptic drugs

Neurology ◽  
2003 ◽  
Vol 61 (12) ◽  
pp. 1793-1795 ◽  
Author(s):  
S. R. Benbadis ◽  
W. O. Tatum ◽  
M. Gieron
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals Antiepileptic drugs withdrawal in patients with idiopathic generalized epilepsy

Seizure ◽  
2011 ◽  
Vol 20 (7) ◽  
pp. 520-525 ◽  
Author(s):  
Milen Pavlović ◽  
Nebojša Jović ◽  
Tatjana Pekmezović
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals Children with idiopathic generalized epilepsy those underwent at least two years seizure remission: a retrospective analysis

2021 ◽  
Vol 8 (9) ◽  
pp. 1508
Author(s):  
Chandan Raybarman
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Care Clinic ◽  
Female Ratio ◽  
Titration Phase ◽  
Male Female Ratio ◽  
Clonic Seizures ◽  
Generalized Epilepsy ◽  
Initial Target

Background: The aim of the retrospective study was to evaluate the effectiveness of the index antiepileptic drugs in children with idiopathic generalized epilepsy who underwent at least 2 years remission.Methods: A total of 52 children with idiopathic generalized epilepsy who underwent at least 2 years remission were identified retrospectively from the records of the paediatric and neurology care clinic from April 2017 to December 2020.Results: The seizure patterns of 52 cases were tonic-clonic seizures alone (73%), a combination of tonic-clonic seizures and absences (13.5%), and combined tonic-clonic seizures and myoclonus (13.5%).  The total number of seizures at enrolment in all (age at seizure onset 7.44±5.12 years, male-female ratio (31:21) was 651 (mean 12.52±26.60). The total number of follow-up visits in all was 6.62±14.44 consisting of 1177.5±772.86 days of follow-up periods. All patients continued index antiepileptic drugs with initial target doses varies from low to moderate ranges. Add-on therapy was initiated in 43% of cases around the titration phase of index antiepileptic drugs (i.e. very early add-on). Treatment trends reveal increased use of 1st generation antiepileptic drugs than 2nd and 3rd generation. 2 years seizure remission rates were 55.77% by index antiepileptic drugs only therapy and 44.23% by very early add-on therapy.  The seizure remission period was mean±SD 858.71±209.08 days.Conclusions: Index antiepileptic drugs with low to moderate initial target doses lead to achieving 2 years or more seizure remission. Very early add-on therapy is the novelty and leads to achieving the goal.

scholarly journals Withdrawal of Antiepileptic Drugs in Patients with Idiopathic Generalized Epilepsy

1997 ◽  
Vol 15 (1) ◽  
pp. 1-6
Author(s):  
Jun Kawasaki ◽  
Kousuke Kanemoto ◽  
Yukiyoshi Shirasaka ◽  
Itsuo Kawai
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals Choice of Antiepileptic Drugs in Idiopathic Generalized Epilepsy: UAE Experience

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Taoufik Alsaadi ◽  
Haytham Taha ◽  
Fatema Al Hammadi
Keyword(s):  
Antiepileptic Drugs ◽  
Broad Spectrum ◽  
Clinic Visit ◽  
Idiopathic Generalized Epilepsy ◽  
Narrow Spectrum ◽  
Generalized Epilepsy ◽  
Electroencephalogram Eeg

We retrospectively reviewed the electroencephalogram (EEG) reports of patients at our EEG lab from the years 2005–2010 to identify patients referred from the epilepsy clinic, with a confirmed diagnosis of idiopathic generalized epilepsy (IGE) by EEG criteria. We sought to report our experience in UAE of how often patients with IGE are placed on nonspecific antiepileptic drugs (AEDs) before being evaluated at an epilepsy referral clinic. 109 patients with a confirmed diagnosis of IGE based on EEG criteria were identified. When initially seen, 32.11% were taking a broad-spectrum (specific) AED only, 25.69% were taking a narrow-spectrum (nonspecific) AED, and 15.59% were placed on various combinations. Of the total patients who were receiving nonspecific AEDs, 35.71% were seizure-free and 64.28% were poorly controlled accounting for “pseudointractability status.” When converted to broad-spectrum (specific) AEDs, 50% became well controlled. Furthermore, 26.6% of patients, who were previously on no AED prior to the clinic visit, became well controlled once placed on specific AED.

A New SYNGAP1 Stop Mutation in a Patient with Idiopathic Generalized Epilepsy Showing Photosensitivity and Electroencephalography Normalization after Eye Opening

2014 ◽  
Vol 45 (S 01) ◽  
Author(s):  
C. von Stülpnagel-Steinbeis ◽  
C. Funke ◽  
C. Haberl ◽  
K. Hörtnagel ◽  
J. Jüngling ◽  
...  
Keyword(s):  
Idiopathic Generalized Epilepsy ◽  
Stop Mutation ◽  
Eye Opening ◽  
Generalized Epilepsy
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