scholarly journals Absence and myoclonic status epilepticus precipitated by antiepileptic drugs in idiopathic generalized epilepsy

Brain ◽  
2006 ◽  
Vol 129 (5) ◽  
pp. 1281-1292 ◽  
Author(s):  
Pierre Thomas ◽  
Luc Valton ◽  
Pierre Genton
Keyword(s):  
Status Epilepticus ◽  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals The genetic variant “C588T” of GABARG2 is linked to childhood idiopathic generalized epilepsy and resistance to antiepileptic drugs

Seizure ◽  
2018 ◽  
Vol 60 ◽  
pp. 39-43 ◽  
Author(s):  
Soheir S. Abou El Ella ◽  
Maha Atef Tawfik ◽  
Wafaa Moustafa M. Abo El Fotoh ◽  
Omar Ahmed M. Soliman
Keyword(s):  
Antiepileptic Drugs ◽  
Genetic Variant ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals Status epilepticus in patients with genetic (idiopathic) generalized epilepsy

2019 ◽  
Vol Volume 15 ◽  
pp. 1585-1592 ◽  
Author(s):  
Magdalena Bosak ◽  
Dominika Pawełczak ◽  
Agnieszka Słowik
Keyword(s):  
Status Epilepticus ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

Idiopathic generalized epilepsy and choice of antiepileptic drugs

Neurology ◽  
2003 ◽  
Vol 61 (12) ◽  
pp. 1793-1795 ◽  
Author(s):  
S. R. Benbadis ◽  
W. O. Tatum ◽  
M. Gieron
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals Antiepileptic drugs withdrawal in patients with idiopathic generalized epilepsy

Seizure ◽  
2011 ◽  
Vol 20 (7) ◽  
pp. 520-525 ◽  
Author(s):  
Milen Pavlović ◽  
Nebojša Jović ◽  
Tatjana Pekmezović
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy

scholarly journals Children with idiopathic generalized epilepsy those underwent at least two years seizure remission: a retrospective analysis

2021 ◽  
Vol 8 (9) ◽  
pp. 1508
Author(s):  
Chandan Raybarman
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Care Clinic ◽  
Female Ratio ◽  
Titration Phase ◽  
Male Female Ratio ◽  
Clonic Seizures ◽  
Generalized Epilepsy ◽  
Initial Target

Background: The aim of the retrospective study was to evaluate the effectiveness of the index antiepileptic drugs in children with idiopathic generalized epilepsy who underwent at least 2 years remission.Methods: A total of 52 children with idiopathic generalized epilepsy who underwent at least 2 years remission were identified retrospectively from the records of the paediatric and neurology care clinic from April 2017 to December 2020.Results: The seizure patterns of 52 cases were tonic-clonic seizures alone (73%), a combination of tonic-clonic seizures and absences (13.5%), and combined tonic-clonic seizures and myoclonus (13.5%).  The total number of seizures at enrolment in all (age at seizure onset 7.44±5.12 years, male-female ratio (31:21) was 651 (mean 12.52±26.60). The total number of follow-up visits in all was 6.62±14.44 consisting of 1177.5±772.86 days of follow-up periods. All patients continued index antiepileptic drugs with initial target doses varies from low to moderate ranges. Add-on therapy was initiated in 43% of cases around the titration phase of index antiepileptic drugs (i.e. very early add-on). Treatment trends reveal increased use of 1st generation antiepileptic drugs than 2nd and 3rd generation. 2 years seizure remission rates were 55.77% by index antiepileptic drugs only therapy and 44.23% by very early add-on therapy.  The seizure remission period was mean±SD 858.71±209.08 days.Conclusions: Index antiepileptic drugs with low to moderate initial target doses lead to achieving 2 years or more seizure remission. Very early add-on therapy is the novelty and leads to achieving the goal.

scholarly journals Withdrawal of Antiepileptic Drugs in Patients with Idiopathic Generalized Epilepsy

1997 ◽  
Vol 15 (1) ◽  
pp. 1-6
Author(s):  
Jun Kawasaki ◽  
Kousuke Kanemoto ◽  
Yukiyoshi Shirasaka ◽  
Itsuo Kawai
Keyword(s):  
Antiepileptic Drugs ◽  
Idiopathic Generalized Epilepsy ◽  
Generalized Epilepsy
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