Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry

10.3791/62672 ◽  
2021 ◽  
Author(s):  
Lingxiao Chaihu ◽  
Xiaopeng Yao ◽  
Xiang Xu ◽  
Zhongqin Zhu ◽  
David D. Y. Chen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Capillary Electrophoresis ◽  
Deuterium Exchange ◽  
Hydrogen Deuterium Exchange ◽  
Top Down ◽  
Hydrogen Deuterium ◽  
Top Down Mass Spectrometry

Characterization of the N370S Mutant of Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry

ChemBioChem ◽  
2012 ◽  
Vol 13 (15) ◽  
pp. 2243-2250 ◽  
Author(s):  
Liangjie Tang ◽  
Stephen J. Coales ◽  
Jeffrey A. Morrow ◽  
Tim Edmunds ◽  
Yoshitomo Hamuro
Keyword(s):  
Mass Spectrometry ◽  
Deuterium Exchange ◽  
Hydrogen Deuterium Exchange ◽  
Exchange Mass Spectrometry ◽  
Hydrogen Deuterium ◽  
Deuterium Exchange Mass Spectrometry
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