scholarly journals Creation and Transplantation of an Adipose-derived Stem Cell (ASC) Sheet in a Diabetic Wound-healing Model

10.3791/54539 ◽  
2017 ◽  
Author(s):  
Yuka Kato ◽  
Takanori Iwata ◽  
Kaoru Washio ◽  
Toshiyuki Yoshida ◽  
Hozue Kuroda ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Diabetic Wound ◽  
Diabetic Wound Healing ◽  
Wound Healing Model ◽  
Adipose Derived Stem Cell ◽  
Healing Model

scholarly journals Enhanced susceptibility to infections in a diabetic wound healing model

BMC Surgery ◽  
2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Tobias Hirsch ◽  
Malte Spielmann ◽  
Baraa Zuhaili ◽  
Till Koehler ◽  
Magdalena Fossum ◽  
...  
Keyword(s):  
Wound Healing ◽  
Diabetic Wound ◽  
Diabetic Wound Healing ◽  
Wound Healing Model ◽  
Healing Model

Evaluation of a multi-layer adipose-derived stem cell sheet in a full-thickness wound healing model

2013 ◽  
Vol 9 (2) ◽  
pp. 5243-5250 ◽  
Author(s):  
Yen-Chih Lin ◽  
Tara Grahovac ◽  
Sun Jung Oh ◽  
Matthew Ieraci ◽  
J. Peter Rubin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Cell Sheet ◽  
Full Thickness ◽  
Wound Healing Model ◽  
Adipose Derived Stem Cell ◽  
Full Thickness Wound ◽  
Healing Model

scholarly journals Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing

2020 ◽  
Vol 15 (2) ◽  
pp. 1277-1293 ◽  
Author(s):  
Jolanta Gorecka ◽  
Xixiang Gao ◽  
Arash Fereydooni ◽  
Biraja C Dash ◽  
Jiesi Luo ◽  
...  
Keyword(s):  
Wound Healing ◽  
Smooth Muscle ◽  
Stem Cell ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Diabetic Wound ◽  
Collagen Scaffolds ◽  
Diabetic Wound Healing ◽  
Induced Pluripotent ◽  
Angiogenic Cytokines

Aim: To assess the potential of human induced pluripotent stem cell-derived smooth muscle cells (hiPSC-SMC) to accelerate diabetic wound healing. Methods: hiPSC-SMC were embedded in 3D collagen scaffolds and cultured in vitro for 72 h; scaffolds were then applied to diabetic, nude mouse, splinted back wounds to assess in vivo healing. Cultured medium after scaffold incubation was collected and analyzed for expression of pro-angiogenic cytokines. Results: hiPSC-SMC secrete increased concentration of pro-angiogenic cytokines, compared with murine adipose derived stem cells. Delivery of hiPSC-SMC-containing collagen scaffolds accelerates diabetic wound healing and is associated with an increased number of total and M2 type macrophages. Conclusion: hiPSC-SMC promote angiogenesis and accelerate diabetic wound healing, making them a promising new candidate for treatment of diabetic wounds.

scholarly journals ECM‐derived Scaffolds: Scaffolds Functionalized with Matrix from Induced Pluripotent Stem Cell Fibroblasts for Diabetic Wound Healing (Adv. Healthcare Mater. 16/2020)

2020 ◽  
Vol 9 (16) ◽  
pp. 2070051
Author(s):  
Francesco Santarella ◽  
Rukmani Sridharan ◽  
Milica Marinkovic ◽  
Ronaldo Jose Farias Correa Do Amaral ◽  
Brenton Cavanagh ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Pluripotent Stem Cell ◽  
Induced Pluripotent Stem Cell ◽  
Diabetic Wound ◽  
Diabetic Wound Healing ◽  
Induced Pluripotent

scholarly journals Stem Cell-Containing Hyaluronic Acid-Based Spongy Hydrogels for Integrated Diabetic Wound Healing

2017 ◽  
Vol 137 (7) ◽  
pp. 1541-1551 ◽  
Author(s):  
Lucília Pereira da Silva ◽  
Tírcia Carlos Santos ◽  
Daniel Barreira Rodrigues ◽  
Rogério Pedro Pirraco ◽  
Mariana Teixeira Cerqueira ◽  
...  
Keyword(s):  
Wound Healing ◽  
Stem Cell ◽  
Hyaluronic Acid ◽  
Diabetic Wound ◽  
Diabetic Wound Healing
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