scholarly journals Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation

10.3791/52912 ◽  
2015 ◽  
Author(s):  
Matthew Flegal ◽  
Melinda S. Blimkie ◽  
Heather Wyatt ◽  
Michelle Bugden ◽  
Joel Surette ◽  
...  
Keyword(s):  
Dna Damage ◽  
Gamma Radiation ◽  
Low Doses ◽  
Dna Damage And Repair ◽  
Mouse Splenocytes

scholarly journals Assessment of in vivo genotoxicity of the rodent carcinogen furan: evaluation of DNA damage and induction of micronuclei in mouse splenocytes

Mutagenesis ◽  
2009 ◽  
Vol 25 (1) ◽  
pp. 57-62 ◽  
Author(s):  
P. Leopardi ◽  
E. Cordelli ◽  
P. Villani ◽  
T. P. Cremona ◽  
L. Conti ◽  
...  
Keyword(s):  
Dna Damage ◽  
Mouse Splenocytes

scholarly journals Identification of Fungi Resistant to 137Cs Gamma Radiation From an Artwork by Candido Portinari

2021 ◽  
Author(s):  
Renata Cardoso ◽  
Fernanda Correa ◽  
Ana Chaves ◽  
Marcia Lutterbach ◽  
Ana Ferreira ◽  
...  
Keyword(s):  
Dna Damage ◽  
Gamma Radiation ◽  
High Efficiency ◽  
Art Collections ◽  
Dna Damage And Repair ◽  
Strand Breaks ◽  
Identification Of Fungi ◽  
Cesium 137 ◽  
Favorable Conditions ◽  
Ionizing Radiation Resistance

Abstract Gamma radiation is a safe and effective technique for the treatment of art collections being used with high efficiency in reducing microbial loads being obtained by the emission of a radioactive isotope, such as Cesium 137. Portinari's work, from the collection of the National Museum (Brazil), was analyzed and the fungi contained therein were collected, isolated, and further treated with gamma radiation for decontamination. Radiation doses used were 16, 19 and 22 kGy. Results indicated 11 genera and 17 species isolated. Penicillium and Cladosporium were isolated in air, artwork and its support - emphasizing the predominance they assume in the contamination of works of art under favorable conditions, such as museums. The genera Penicillium, Cladosporium, Nigrospora and Curvularia showed high resistances (16 kGy). The most resistant was Cladosporium, which showed no growth under 22 kGy. As there are some differences in ionizing radiation resistance among fungi from the same order or species, the results here outlined indicates that the rates of DNA damage and repair were critical, depending on chronic or acute dose irradiated. The biochemical mechanism acting on fungal cells under irradiation was basically the inactivation of specific enzymes and, probably, DNA damage, particularly stimulating double-strand breaks.

scholarly journals Dynamic In Vivo Profiling of DNA Damage and Repair after Radiotherapy Using Canine Patients as a Model

2017 ◽  
Vol 18 (6) ◽  
pp. 1176 ◽  
Author(s):  
Nadine Schulz ◽  
Hassan Chaachouay ◽  
Katarzyna Nytko ◽  
Mathias Weyland ◽  
Malgorzata Roos ◽  
...  
Keyword(s):  
Dna Damage ◽  
Dna Damage And Repair

scholarly journals Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair

2009 ◽  
Vol 36 (8) ◽  
pp. 975-983 ◽  
Author(s):  
Yanming Wang ◽  
Lili Liu ◽  
Chunying Wu ◽  
Alina Bulgar ◽  
Eduardo Somoza ◽  
...  
Keyword(s):  
Dna Damage ◽  
Direct Detection ◽  
In Vivo Studies ◽  
Dna Damage And Repair ◽  
Abasic Sites ◽  
Detection And Quantification
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