scholarly journals Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

10.3791/2225 ◽  
2010 ◽  
Author(s):  
Lucia M.A. Crane ◽  
George Themelis ◽  
Tim Buddingh ◽  
Niels J. Harlaar ◽  
Rick G. Pleijhuis ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Real Time ◽  
Fluorescence Imaging ◽  
Gynecologic Oncology ◽  
Intraoperative Detection

Comparison of Real-Time Fluorescent Indocyanine Green and 99mTc-Nanocolloid Radiotracer Navigation in Sentinel Lymph Node Biopsy of Penile Cancer

2015 ◽  
Vol 13 (6) ◽  
pp. 574-580 ◽  
Author(s):  
Marcin Markuszewski ◽  
Wojciech Polom ◽  
Wojciech Cytawa ◽  
Piotr Czapiewski ◽  
Piotr Lass ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Indocyanine Green ◽  
Real Time ◽  
Penile Cancer ◽  
Lymph Node Biopsy ◽  
Node Biopsy

Real-Time Reverse-Transcription PCR to Quantify a Panel of 19 Genes in Breast Cancer: Relationships with Sentinel Lymph Node Invasion

2008 ◽  
Vol 23 (1) ◽  
pp. 10-17 ◽  
Author(s):  
F. Révillion ◽  
V. Lhotellier ◽  
L. Hornez ◽  
A. Leroy ◽  
M.C. Baranzelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Growth Factor ◽  
Sentinel Lymph Node ◽  
Real Time ◽  
Critical Role ◽  
Cytokeratin 19 ◽  
Axillary Lymph ◽  
Mucin 1 ◽  
Her3 Expression

At the Centre Oscar Lambret, the anticancer centre of the North of France, sentinel lymph node (SLN) procedures are routinely performed for localized (T0–T1, N0, M0) breast carcinoma without any previous treatment, in order to prevent the deleterious effects of axillary lymph node dissection. The present study was undertaken to assess if the expression in the tumor of a panel of 19 genes would allow to predict histological SLN involvement. We looked at cytokeratin 19 (CK19), mucin-1 (MUC1), mammaglobin (MGB1), cyclin D1 (CCND1), the four members of the HER/ErbB growth factor receptor family (EGFR, HER2–4), insulin-like growth factor-1 receptor (IGF-1R), estradiol receptors (ERcx, ERβ), progesterone receptor (PR), vascular endothelial growth factors (VEGF, VEGF-C), urokinase-like plasminogen activator (uPA), matrix metalloproteinases 2 and 9 (MMP2, MMP9), ets-related transcription factor ERM, and E-cadherin (CDH1). Their expression was quantified by real-time RT-PCR in 134 breast cancer samples and the relationships with SLN metastases were analyzed. A slight increase (35–40%) in CK19 and HER3 expression was observed in the tumors of patients with SLN metastases compared to those of patients without metastases, even if neither CK19 expression nor HER3 expression allowed to distinguish patients with micrometastases from patients with macrometastases. We conclude that the tumoral expression of biological parameters involved in cell proliferation or playing a critical role in the metastatic process, including tumor invasion and angiogenesis, is not strongly associated with SLN metastases.

257. Sentinel Lymph Node Biopsy with Real-time 3D Virtual Navigation

2012 ◽  
Vol 38 (9) ◽  
pp. 815 ◽  
Author(s):  
M. Suzuki ◽  
K. Koda ◽  
M. Yamazaki ◽  
T. Tezuka ◽  
C. Kosugi ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Real Time ◽  
Lymph Node Biopsy ◽  
Virtual Navigation ◽  
Node Biopsy
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