Boys Town National Research Hospital: Past, Present, and Future

2017 ◽  
Vol 28 (09) ◽  
pp. 776-777
Author(s):  
Kristen Janky ◽  
Ryan McCreery ◽  
Walt Jesteadt
Keyword(s):  
Research Hospital ◽  
Boys Town

İŞE BAĞLILIĞIN TÜKENMİŞLİK VE DEPRESYON DÜZEYLERİ ÜZERİNDEKİ ETKİLERİ: SAĞLIK ÇALIŞANLARI ÜZERİNDE BİR ARAŞTIRMA

2014 ◽  
Vol 1 (2) ◽  
pp. 206
Author(s):  
Haluk TANRIVERDİ ◽  
Mucize SARIHAN
Keyword(s):  
Regression Analysis ◽  
Correlation Analysis ◽  
Health Workers ◽  
Personal Information ◽  
Depression Scale ◽  
Work Commitment ◽  
Statistical Software ◽  
Research Hospital ◽  
Training And Research

The main purpose of this study is to examine the effects of health workers’ levels of work commitment on the levels of depression and burnout.  Having this purpose in mind, a questionnaire consisting of personal information form, work commitment scale, burnout scale and depression scale was conducted with 266 health workers of İstanbul Kartal Training and Research Hospital in May 2013. Data obtained from questionnaires were analyzed by SPSS 17,0 statistical software. Correlation analysis was utilized in order to determine the relationships among work commitment, burnout and depression levels of health workers whereas regression analysis was utilized in order to determine the effects of health workers’ levels of work commitment on the levels of depression and burnout. According to the results, it has been found that there are statistically relevant relationships among work commitment, burnout and depression levels of health workers. It has been concluded that the more health workers’ levels of work commitment increase, their levels of depression and burnout decrease.

Platelet distribution width in young patients with chronic venous insufficiency

Vascular ◽  
2021 ◽  
pp. 170853812110296
Author(s):  
Mustafa Aldemir ◽  
Ahmet Yuksel ◽  
Mehmet Inanir ◽  
Salih Metin ◽  
Yusuf Velioglu ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Clinical Features ◽  
Chronic Venous Insufficiency ◽  
Venous Insufficiency ◽  
Young Patients ◽  
Control Group ◽  
Platelet Distribution Width ◽  
Distribution Width ◽  
Research Hospital ◽  
Lymphocyte Ratio

Objective Platelet distribution width (PDW) has been reported in a wide range of pathological settings. In this study, we aimed to investigate the relationship between PDW and lower extremity chronic venous insufficiency (CVI) by comparing the levels of PDW and other parameters derived from complete blood count (CBC) tests in young individuals with or without lower extremity CVI. Methods This prospective clinical study was conducted between January 2020 and December 2020. A total of 108 patients, 72 patients with lower extremity CVI (study group) and 36 healthy volunteers (control group) were enrolled from the Bursa Yuksek Ihtısas Educatıon Research Hospıtal and the Bolu Abant Izzet Baysal University Training and Research Hospital. The age range of the participants was between 18 and 50 years old. Participants’ baseline clinical features and CBC parameters including PDW, white blood cell, hemoglobin, hematocrit, mean corpuscular volume, red cell distribution width, neutrophil, lymphocyte, platelet count, mean platelet volume, plateletcrit, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio were compared between the two groups. Results The groups were statistically similar in terms of baseline clinical features. The median PDW value was significantly higher for the CVI patients relative to the control group (17.6 vs 16.8; p < 0.001). In terms of other CBC parameters, there were no significant differences between the groups. According to ROC analysis, area under the curve of PDW was 0.749 (95% confidence interval: 0.653–0.846 and p < 0.001). If the value of PDW was accepted as 17, it could predict CVI with 76% sensitivity and 59% specificity, whereas a PDW value of 17.5 could predict CVI with 51% sensitivity and 81% specificity. Conclusion Platelet distribution width might be a useful marker to determine an increased inflammatory response and thrombotic status in young patients with CVI.

Survival and Neurodevelopmental Outcome of Young Children With Medulloblastoma at St Jude Children's Research Hospital

1999 ◽  
Vol 17 (12) ◽  
pp. 3720-3728 ◽  
Author(s):  
Andrew W. Walter ◽  
Raymond K. Mulhern ◽  
Amar Gajjar ◽  
Richard L. Heideman ◽  
David Reardon ◽  
...  
Keyword(s):  
Survival Rate ◽  
Young Children ◽  
Disease Progression ◽  
Hormone Replacement ◽  
Neurodevelopmental Outcome ◽  
Progression Free Survival ◽  
Research Hospital ◽  
Entire Cohort ◽  
Salvage Radiation Therapy ◽  
Long Term Survivors

PURPOSE: Young children treated for medulloblastoma are at especially high risk for morbidity and mortality from their disease and therapy. This study sought to assess the relationship, if any, between patient outcome and M stage. Neuropsychologic and endocrine outcomes were also assessed. PATIENTS AND METHODS: Twenty-nine consecutively diagnosed infants and young children were treated for medulloblastoma at St Jude Children's Research Hospital between November 1984 and December 1995. All patients were treated with the intent of using postoperative chemotherapy to delay planned irradiation. RESULTS: The median age at diagnosis was 2.6 years. Six patients completed planned chemotherapy without progressive disease and underwent irradiation at completion of chemotherapy. Twenty-three children experienced disease progression during chemotherapy and underwent irradiation at the time of progression. The 5-year overall survival rate for the entire cohort was 51% ± 10%. The 5-year progression-free survival rate was 21% ± 8%. M stage did not impact survival. All patients lost cognitive function during and after therapy at a rate of −3.9 intelligence quotient points per year (P = .0028). Sensory functions declined significantly after therapy (P = .007). All long-term survivors required hormone replacement therapy and had growth abnormalities. CONCLUSION: The majority of infants treated for medulloblastoma experienced disease progression during initial chemotherapy. However, more than half of these patients can be cured with salvage radiation therapy, regardless of M stage. The presence of metastatic disease did not increase the risk of dying from medulloblastoma. All patients treated in this fashion have significant neuropsychologic deficits. Our experience demonstrates that medulloblastoma in infancy is a curable disease, albeit at a significant cost.

The orbital research hospital

1967 ◽  
Author(s):  
D. JONES ◽  
B. NEWSOM
Keyword(s):  
Research Hospital

scholarly journals Psychotropic Drug Use in Children with Autism Spectrum Disorder Admitted to a Training and Research Hospital Outpatient Clinic: A Retrospective Cross-Sectional Study

2020 ◽  
Vol 10 (01) ◽  
pp. e233-e239
Author(s):  
Sabide Duygu Uygun ◽  
Fatma Hülya Çakmak ◽  
Merve Canlı ◽  
Rahime Duygu Temeltürk ◽  
Ayşegül Efe ◽  
...  
Keyword(s):  
Drug Use ◽  
Psychotropic Drug ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Psychiatric Comorbidities ◽  
Research Hospital ◽  
Clinical Variables ◽  
Hospital Outpatient Clinic ◽  
Psychotropic Drug Use ◽  
Training And Research

AbstractThis study aimed to examine demographic and clinical variables, psychiatric comorbidities, the prevalence of psychotropic drug use, relationships between drug use, demographic and clinical variables, and predictors of drug use in children with autism spectrum disorder (ASD) admitted to a training and research hospital outpatient clinic. Four hundred and eleven children with ASD admitted to the Department of Child and Adolescent Psychiatry, Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital, between October 1, 2019 and December 31, 2019, were retrospectively reviewed. Demographic and clinical variables, psychiatric comorbidities, and characteristics of drug use for the cases were recorded. Psychotropic drug use was found in 34.3% (n = 141) of the cases. Our results revealed male sex and psychiatric comorbidity as predictors of psychotropic drug use. Antipsychotics were the most prescribed drugs, and the most common psychiatric comorbidity was conduct disorder. Also, children with ASD who had been toilet-trained, and could express sentences but were illiterate, were using psychotropic drugs more often than others. Future multicentered, large clinic-based studies from training and research hospitals should focus on trends of treatment in psychiatric comorbidities accompanying ASD, and constitute a systematic approach for the psychopharmacological treatment of these cases.

Cure of Acute Lymphocytic Leukemia Following Relapse

PEDIATRICS ◽  
1987 ◽  
Vol 79 (4) ◽  
pp. 650-651
Author(s):  
GASTON K. RIVERA ◽  
SHARON B. MURPHY
Keyword(s):  
Acute Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Childhood All ◽  
Research Hospital ◽  
Disease Free

We read with some interest the article by Musgrave et al (Pediatrics 1986;77:765-769) presenting information on 72 children with acute lymphocytic leukemia (ALL) who have survived disease-free 5 years or longer in their second or subsequent remission. The purpose of this letter is to share our experience at St Jude Children's Research Hospital, an institution that has been engaged in the research and treatment of childhood ALL since 1962. We now have more than 600 children with ALL who are off therapy in remission of their disease.

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