scholarly journals Synthesis of the fluorescent amino acid rac-(7-hydroxycoumarin-4-yl)ethylglycine

2010 ◽  
Vol 6 ◽  
Author(s):  
Manfred Braun ◽  
Torsten Dittrich
Keyword(s):  
Acetic Acid ◽  
Amino Acid ◽  
Fluorescent Probe ◽  
Fluorescent Amino Acid ◽  
Racemic Amino Acid

The hydrochloride of the racemic amino acid (7-hydroxycoumarin-4-yl)ethylglycine, a versatile fluorescent probe in proteins, has been synthesized in five steps from commercially available (7-hydroxycoumarin-4-yl)acetic acid. The key step involves the alkylation of a glycine–enolate equivalent.

scholarly journals A new synthetic protocol for coumarin amino acid

2013 ◽  
Vol 9 ◽  
pp. 254-259 ◽  
Author(s):  
Xinyi Xu ◽  
Xiaosong Hu ◽  
Jiangyun Wang
Keyword(s):  
Amino Acid ◽  
Fluorescent Probe ◽  
Synthetic Method ◽  
Fluorescent Amino Acid ◽  
Racemic Amino Acid ◽  
Derivatives Of ◽  
Coumarin Amino Acid

The hydrochloride of the racemic amino acid (2-(7-hydroxycoumarin-4-yl)ethyl)glycine, which can serve as a fluorescent probe in proteins, and two halogen derivatives of it, were synthesized by using a new synthetic protocol in five steps. It is less costly and relatively easy to prepare this kind of fluorescent amino acid with the new synthetic method. Furthermore, it can be applied to synthesize other derivatives of the coumarin amino acid with some specific properties.

Increased expression of an amino acid transporter LAT1 in healing of acetic acid-induced chronic gastric ulcer in rats

2001 ◽  
Vol 120 (5) ◽  
pp. A153-A153
Author(s):  
S MIYAMOTO ◽  
K KATO ◽  
Y ISHII ◽  
S ASAI ◽  
T NAGAISHI ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Gastric Ulcer ◽  
Amino Acid ◽  
Amino Acid Transporter ◽  
Chronic Gastric Ulcer ◽  
Acid Transporter

Synthesis of amino acid derivatives of indole-3-acetic acid

2005 ◽  
Vol 2005 (10) ◽  
pp. 640-642 ◽  
Author(s):  
Ying Liu ◽  
Liang Zhao ◽  
Liang Liu ◽  
Lin-Yi Wei ◽  
Lu-Hua Lai
Keyword(s):  
Acetic Acid ◽  
Amino Acid ◽  
Amino Acid Derivatives ◽  
H Nmr ◽  
Derivatives Of ◽  
Indole 3 Acetic Acid

Amino acid derivatives of a modified indole-3-acetic acid have been synthesised. Fourteen new dipeptide-like compounds 3–4 were obtained and their structures were elucidated based on the IR, 1H NMR, MS spectra.

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