scholarly journals Photophysics and photochemistry of NIR absorbers derived from cyanines: key to new technologies based on chemistry 4.0

2020 ◽  
Vol 16 ◽  
pp. 415-444 ◽  
Author(s):  
Bernd Strehmel ◽  
Christian Schmitz ◽  
Ceren Kütahya ◽  
Yulian Pang ◽  
Anke Drewitz ◽  
...  
Keyword(s):  
Electrochemical Properties ◽  
High Power ◽  
Near Infrared ◽  
New Technologies ◽  
Light Sources ◽  
Hydrophobic Properties ◽  
On Demand ◽  
Nir Light ◽  
Photothermal Treatment ◽  
End Groups

Cyanines derived from heptamethines were mainly discussed regarding their functionalization to broaden the solubility in different surroundings exhibiting either hydrophilic or hydrophobic properties and to tailor made the ΔG et photopysical properties with respect to absorption and fluorescence. Electrochemical properties were additionally considered for some selected examples. The cyanines chosen comprised as end groups either indolenine, benzo[e]- or benzo[cd]indolium pattern, which facilitated to shift the absorption between 750–1000 nm. This enabled their use in applications with light sources emitting in the near-infrared (NIR) region selected from high power LEDs or lasers with line-shaped focus. The absorbers considered were discussed regarding their function as sensitizer for applications related to Chemistry 4.0 standards. These were mainly photopolymer coatings, which can be found for applications in the graphic industry or to protect selected substrates. The huge release of heat on demand upon turning ON or OFF the NIR light source enables them for photothermal treatment in processes requesting heat to initiate either chemical (activated reactions) or physical (melting, evaporation) events.

Spectrally tunable and thermally stable near-infrared luminescence in Na3Sc2(PO4)3:Cr3+ phosphor by Ga3+ co-doping for light-emitting diodes

2021 ◽  
Author(s):  
Shihai Miao ◽  
Yanjie Liang ◽  
Yan Zhang ◽  
Dongxun Chen ◽  
Shao Yan ◽  
...  
Keyword(s):  
High Power ◽  
Near Infrared ◽  
Light Emitting Diodes ◽  
Light Sources ◽  
Thermally Stable ◽  
Light Emitting ◽  
Co Doping ◽  
Nir Light ◽  
Infrared Luminescence ◽  
Promising Solution

Near-infrared (NIR) phosphor-converted light-emitting diodes (LEDs) are becoming an efficient and promising solution for high-power NIR light sources, which have shown a broad range of possible applications in the fields...

scholarly journals Nanocomposite Sprayed Films with Photo-Thermal Properties for Remote Bacteria Eradication

Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 786 ◽  
Author(s):  
Mykola Borzenkov ◽  
Giuseppe Chirico ◽  
Piersandro Pallavicini ◽  
Paola Sperandeo ◽  
Alessandra Polissi ◽  
...  
Keyword(s):  
Near Infrared ◽  
Light Exposure ◽  
Antibacterial Properties ◽  
Remarkable Effect ◽  
On Demand ◽  
Nir Light ◽  
Positive Strain ◽  
Glass Slides ◽  
Active Nanoparticles ◽  
Further Development

Currently there is a strong demand for novel protective materials with efficient antibacterial properties. Nanocomposite materials loaded with photo-thermally active nanoparticles can offer promising opportunities due to the local increase of temperature upon near-infrared (NIR) light exposure capable of eradicating bacteria. In this work, we fabricated antibacterial films obtained by spraying on glass slides aqueous solutions of polymers, containing highly photo-thermally active gold nanostars (GNS) or Prussian Blue (PB) nanoparticles. Under NIR light irradiation with low intensities (0.35 W/cm2) these films demonstrated a pronounced photo-thermal effect: ΔTmax up to 26.4 °C for the GNS-containing films and ΔTmax up to 45.8 °C for the PB-containing films. In the latter case, such a local temperature increase demonstrated a remarkable effect on a Gram-negative strain (P. aeruginosa) killing (84% of dead bacteria), and a promising effect on a Gram-positive strain (S. aureus) eradication (69% of dead bacteria). The fabricated films are promising prototypes for further development of lightweight surfaces with efficient antibacterial action that can be remotely activated on demand.

scholarly journals Preparation of injectable hydrogel with near-infrared light response and photo-controlled drug release

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Jianbo Zhao ◽  
Xingxing Liang ◽  
Hui Cao ◽  
Tianwei Tan
Keyword(s):  
Drug Release ◽  
Near Infrared ◽  
Controlled Drug Release ◽  
Proteinase K ◽  
Infrared Light ◽  
Light Sources ◽  
Cytotoxicity Test ◽  
Polyaspartic Acid ◽  
On Demand

AbstractPhoto-controlled release hydrogel provides a new strategy for treating tumours. Under the stimulation of external light sources, the ability to release the entrapped drug on time and space on demand has outstanding advantages in improving drug utilisation, optimising treatment, and reducing toxicity and side effects. In this study, a photo-controlled drug delivery system for disulphide cross-linked polyaspartic acid (PASP-SS) hydrogels encapsulating proteinase K (ProK) adsorbed with platinum nanoparticles (PtNPs) was designed. The injectable cysteamine-modified polyaspartic acid (PASP-SH) sol and PtNPs adsorbed by ProK (ProK-PtNPs) as regulatory factors were prepared. Then, ProK-PtNPs and lentinan were dissolved in the sol, and the oxidant was added to the matrix to form the gel in situ quickly after injection. Finally, the degradation of PASP-SS hydrogel by ProK and the controllability of drug release under near-infrared (NIR) light irradiation were elucidated. In vitro degradation of hydrogels and drug release experiments showed that the degradation rate of PASP-SS hydrogel significantly increased and the drug release rate increased significantly under near-infrared radiation. The results of cytotoxicity test showed that PASP-SS, ProK-PtNPs, and lentinan all had more than 90% cell survival rate on NIH3T3, and the lentinan released from the carrier obviously inhibited the proliferation of MCF7. PASP hydrogel has the potential to respond to on-demand light control.

Site engineering strategy toward enhanced luminescence thermostability of Cr3+ doped broadband NIR phosphor and its application

2021 ◽  
Author(s):  
Shengqiang Liu ◽  
Hao Cai ◽  
Shiyou Zhang ◽  
Zhen Song ◽  
Zhiguo Xia ◽  
...  
Keyword(s):  
Food Analysis ◽  
Near Infrared ◽  
State Of The Art ◽  
Light Sources ◽  
Nir Light ◽  
Luminescence Efficiency ◽  
Engineering Strategy ◽  
Enhanced Luminescence

Efficient broadband near-infrared (NIR) light sources are urgently needed for emeging applications in medicine and food analysis etc. Nevertheless, performance is limited by luminescence efficiency and thermostability in state-of-the-art broadband...

scholarly journals Near-infrared light-triggered nano-prodrug for cancer gas therapy

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Runcong Liu ◽  
Yongjun Peng ◽  
Ligong Lu ◽  
Shaojun Peng ◽  
Tianfeng Chen ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Near Infrared ◽  
Treatment Method ◽  
Infrared Light ◽  
Deep Penetration ◽  
Normal Tissues ◽  
On Demand ◽  
Nir Light ◽  
Gas Molecules ◽  
Ongoing Development

AbstractGas therapy (GT) has attracted increasing attention in recent years as a new cancer treatment method with favorable therapeutic efficacy and reduced side effects. Several gas molecules, such as nitric oxide (NO), carbon monoxide (CO), hydrogen (H2), hydrogen sulfide (H2S) and sulfur dioxide (SO2), have been employed to treat cancers by directly killing tumor cells, enhancing drug accumulation in tumors or sensitizing tumor cells to chemotherapy, photodynamic therapy or radiotherapy. Despite the great progress of gas therapy, most gas molecules are prone to nonspecific distribution when administered systemically, resulting in strong toxicity to normal tissues. Therefore, how to deliver and release gas molecules to targeted tissues on demand is the main issue to be considered before clinical applications of gas therapy. As a specific and noninvasive stimulus with deep penetration, near-infrared (NIR) light has been widely used to trigger the cleavage and release of gas from nano-prodrugs via photothermal or photodynamic effects, achieving the on-demand release of gas molecules with high controllability. In this review, we will summarize the recent progress in cancer gas therapy triggered by NIR light. Furthermore, the prospects and challenges in this field are presented, with the hope for ongoing development.

Bio-inspired Janus composite nanoscrolls for on-demand tumour targeting

RSC Advances ◽  
2016 ◽  
Vol 6 (21) ◽  
pp. 17179-17187 ◽  
Author(s):  
Jeong-Hwan Kim ◽  
Tsai-Ming Lu
Keyword(s):  
Near Infrared ◽  
Tumour Targeting ◽  
On Demand ◽  
Nir Light

Inspired by the responsive characteristics of natural fibrous counterparts, triple stimuli, pH-, drug-, and near-infrared (NIR) light-responsive Janus composite nanosheets (JCNs) were investigated.

scholarly journals Repeatable and adjustable on-demand sciatic nerve block with phototriggerable liposomes

2015 ◽  
Vol 112 (51) ◽  
pp. 15719-15724 ◽  
Author(s):  
Alina Y. Rwei ◽  
Jung-Jae Lee ◽  
Changyou Zhan ◽  
Qian Liu ◽  
Meryem T. Ok ◽  
...  
Keyword(s):  
Cell Culture ◽  
Sciatic Nerve ◽  
Local Anesthesia ◽  
Nerve Block ◽  
Near Infrared ◽  
Tissue Reaction ◽  
On Demand ◽  
Nir Light

Pain management would be greatly enhanced by a formulation that would provide local anesthesia at the time desired by patients and with the desired intensity and duration. To this end, we have developed near-infrared (NIR) light-triggered liposomes to provide on-demand adjustable local anesthesia. The liposomes contained tetrodotoxin (TTX), which has ultrapotent local anesthetic properties. They were made photo-labile by encapsulation of a NIR-triggerable photosensitizer; irradiation at 730 nm led to peroxidation of liposomal lipids, allowing drug release. In vitro, 5.6% of TTX was released upon NIR irradiation, which could be repeated a second time. The formulations were not cytotoxic in cell culture. In vivo, injection of liposomes containing TTX and the photosensitizer caused an initial nerve block lasting 13.5 ± 3.1 h. Additional periods of nerve block could be induced by irradiation at 730 nm. The timing, intensity, and duration of nerve blockade could be controlled by adjusting the timing, irradiance, and duration of irradiation. Tissue reaction to this formulation and the associated irradiation was benign.

Catalyst Halogenation Enables Rapid and Efficient Polymerizations with Visible to Near-Infrared Light

2020 ◽  
Author(s):  
Alex Stafford ◽  
Dowon Ahn ◽  
Emily Raulerson ◽  
Kun-You Chung ◽  
Kaihong Sun ◽  
...  
Keyword(s):  
Near Infrared ◽  
Transient Absorption ◽  
Reaction Times ◽  
Infrared Light ◽  
Structure Property ◽  
Light Emitting ◽  
Structure Property Relationships ◽  
Nir Light ◽  
Light Intensities ◽  
Emission Quenching

Driving rapid polymerizations with visible to near-infrared (NIR) light will enable nascent technologies in the emerging fields of bio- and composite-printing. However, current photopolymerization strategies are limited by long reaction times, high light intensities, and/or large catalyst loadings. Improving efficiency remains elusive without a comprehensive, mechanistic evaluation of photocatalysis to better understand how composition relates to polymerization metrics. With this objective in mind, a series of methine- and aza-bridged boron dipyrromethene (BODIPY) derivatives were synthesized and systematically characterized to elucidate key structure-property relationships that facilitate efficient photopolymerization driven by visible to NIR light. For both BODIPY scaffolds, halogenation was shown as a general method to increase polymerization rate, quantitatively characterized using a custom real-time infrared spectroscopy setup. Furthermore, a combination of steady-state emission quenching experiments, electronic structure calculations, and ultrafast transient absorption revealed that efficient intersystem crossing to the lowest excited triplet state upon halogenation was a key mechanistic step to achieving rapid photopolymerization reactions. Unprecedented polymerization rates were achieved with extremely low light intensities (< 1 mW/cm<sup>2</sup>) and catalyst loadings (< 50 μM), exemplified by reaction completion within 60 seconds of irradiation using green, red, and NIR light-emitting diodes.

Bi19S27I3 nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Research Interest ◽  
The Past ◽  
Nir Light ◽  
Considerable Research ◽  
Key Factor

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...

scholarly journals Analysis on High-Power Seaport LED Luminaire with Uniform Light Distribution Based on Optimized Lens and Heatsink

2021 ◽  
Vol 11 (9) ◽  
pp. 4035
Author(s):  
Jinsheon Kim ◽  
Jeungmo Kang ◽  
Woojin Jang
Keyword(s):  
Light Source ◽  
High Power ◽  
Heat Dissipation ◽  
Light Emitting Diode ◽  
Light Distribution ◽  
Light Sources ◽  
Led Light ◽  
High Power Led ◽  
Distribution Requirement ◽  
Lighting Application

In the case of light-emitting diode (LED) seaport luminaires, they should be designed in consideration of glare, average illuminance, and overall uniformity. Although it is possible to implement light distribution through auxiliary devices such as reflectors, it means increasing the weight and size of the luminaire, which reduces the feasibility. Considering the special environment of seaport luminaires, which are installed at a height of 30 m or more, it is necessary to reduce the weight of the device, facilitate replacement, and secure a light source with a long life. In this paper, an optimized lens design was investigated to provide uniform light distribution to meet the requirement in the seaport lighting application. Four types of lens were designed and fabricated to verify the uniform light distribution requirement for the seaport lighting application. Using numerical analysis, we optimized the lens that provides the required minimum overall uniformity for the seaport lighting application. A theoretical analysis for the heatsink structure and shape were conducted to reduce the heat from the high-power LED light sources up to 250 W. As a result of these analyses on the heat dissipation characteristics of the high-power LED light source used in the LED seaport luminaire, the heatsink with hexagonal-shape fins shows the best heat dissipation effect. Finally, a prototype LED seaport luminaire with an optimized lens and heat sink was fabricated and tested in a real seaport environment. The light distribution characteristics of this prototype LED seaport luminaire were compared with a commercial high-pressure sodium luminaire and metal halide luminaire.

Sign in / Sign up

Export Citation Format

Share Document