scholarly journals 1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis

2016 ◽  
Vol 12 ◽  
pp. 918-936 ◽  
Author(s):  
Antonia Mielgo ◽  
Claudio Palomo
Keyword(s):  
Asymmetric Catalysis ◽  
Asymmetric Reactions ◽  
Chiral Catalysts ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Reactions

Asymmetric catalysis represents a very powerful tool for the synthesis of enantiopure compounds. In this context the main focus has been directed not only to the search for new efficient chiral catalysts, but also to the development of efficient pronucleophiles. This review highlights the utility and first examples of 1H-imidazol-4(5H)-ones and thiazol-4(5H)-ones as pronucleophiles in catalytic asymmetric reactions.

Deconjugated butenolide: a versatile building block for asymmetric catalysis

2020 ◽  
Vol 49 (18) ◽  
pp. 6755-6788 ◽  
Author(s):  
Abhijnan Ray Choudhury ◽  
Santanu Mukherjee
Keyword(s):  
Asymmetric Catalysis ◽  
Building Block ◽  
Enantioselective Synthesis ◽  
Asymmetric Reactions ◽  
Comprehensive Overview ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Reactions

Deconjugated butenolides have emerged as a popular synthon for the enantioselective synthesis of γ-lactones. This review provides a comprehensive overview on the catalytic asymmetric reactions of deconjugated butenolides reported till date.

scholarly journals Recent Advances in the Catalytic Asymmetric Reactions of Oxaziridines

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2656 ◽  
Author(s):  
Qiao Ren ◽  
Wen Yang ◽  
Yunfei Lan ◽  
Xurong Qin ◽  
Youzhou He ◽  
...  
Keyword(s):  
Asymmetric Catalysis ◽  
Asymmetric Reactions ◽  
Nitrogen Transfer ◽  
Asymmetric Transformations ◽  
Recent Advances ◽  
Broad Array ◽  
Catalytic Asymmetric ◽  
Transfer Agents ◽  
Catalytic Asymmetric Reactions

Oxaziridines have emerged as powerful and elegant oxygen- and nitrogen-transfer agents for a broad array of nucleophiles, due to the remarkably high and tunable reactivities. However, the asymmetric catalysis involving oxaziridines is still in its infancy. Herein, this review aims to examine recent advances in the catalytic asymmetric transformations of oxaziridines, including oxidation, amination, cycloaddition and deracemization.

scholarly journals Pyrazoleamides in Catalytic Asymmetric Reactions: Recent Advances

2021 ◽  
Author(s):  
Sara Meninno ◽  
Francesca Franco ◽  
Maurizio Benaglia ◽  
Alessandra Lattanzi
Keyword(s):  
Asymmetric Reactions ◽  
Recent Advances ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Reactions

A Facile Synthesis of the Enantiopure, Nitrogen-Substituted 2,2'-Diamino-1,1'-binaphthyls as Potential Ligands for Catalytic Asymmetric Reactions

1998 ◽  
Vol 63 (4) ◽  
pp. 515-519 ◽  
Author(s):  
Štěpán Vyskočil ◽  
Martin Smrčina ◽  
Pavel Kočovský
Keyword(s):  
Room Temperature ◽  
Asymmetric Reactions ◽  
Reductive Alkylation ◽  
Facile Synthesis ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Reactions

Reductive alkylation of (R)-(+)-2,2'-diamino-1,1'-binaphthyl (1) with various ketones has been accomplished by means of NaBH4/H2SO4 in THF at room temperature. Bisalkylation predominated with the sterically less demanding acetone (1→3a; 82%), whereas the bulky 2-adamantanone afforded mainly the monoalkylated product 4c (71%). Both mono- and bisalkylated diamines (R)-3 and (R)-4 were reductively permethylated on reaction with CH2O, NaBH4, and H2SO4. The Pd(0)-catalyzed phenylation of (R)-(+)-1 with PhBr afforded the N,N'-diphenyl derivative (R)-7 (70%).

Sign in / Sign up

Export Citation Format

Share Document