scholarly journals Excitatory backward conditioning of defensive burying in rats

1982 ◽  
Vol 19 (2) ◽  
pp. 111-114 ◽  
Author(s):  
Marica L. Spetch ◽  
Lori J. Terlecki ◽  
John P. J. Pinel ◽  
Donald M. Wilkie ◽  
Dallas Treit
Keyword(s):  
Backward Conditioning ◽  
Defensive Burying

scholarly journals Participation ofGABAAChloride Channels in the Anxiolytic-Like Effects of a Fatty Acid Mixture

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Juan Francisco Rodríguez-Landa ◽  
Rosa Isela García-Ríos ◽  
Jonathan Cueto-Escobedo ◽  
Blandina Bernal-Morales ◽  
Carlos M. Contreras
Keyword(s):  
Open Field ◽  
Field Test ◽  
Chloride Channels ◽  
Wistar Rats ◽  
Elevated Plus Maze ◽  
Open Field Test ◽  
Acid Mixture ◽  
Plus Maze ◽  
Gaba Binding ◽  
Defensive Burying

Human amniotic fluid and a mixture of eight fatty acids (FAT-M) identified in this maternal fluid (C12:0, lauric acid, 0.9 μg%; C14:0, myristic acid, 6.9 μg%; C16:0, palmitic acid, 35.3 μg%; C16:1, palmitoleic acid, 16.4 μg%; C18:0, stearic acid, 8.5 μg%; C18:1cis, oleic acid, 18.4 μg%; C18:1trans, elaidic acid, 3.5 μg%; C18:2, linoleic acid, 10.1 μg%) produce anxiolytic-like effects that are comparable to diazepam in Wistar rats, suggesting the involvement ofγ-aminobutyric acid-A (GABAA) receptors, a possibility not yet explored. Wistar rats were subjected to the defensive burying test, elevated plus maze, and open field test. In different groups, threeGABAAreceptor antagonists were administered 30 min before FAT-M administration, including the competitive GABA binding antagonist bicuculline (1 mg/kg),GABAAbenzodiazepine antagonist flumazenil (5 mg/kg), and noncompetitiveGABAAchloride channel antagonist picrotoxin (1 mg/kg). The FAT-M exerted anxiolytic-like effects in the defensive burying test and elevated plus maze, without affecting locomotor activity in the open field test. TheGABAAantagonists alone did not produce significant changes in the behavioral tests. Picrotoxin but not bicuculline or flumazenil blocked the anxiolytic-like effect of the FAT-M. Based on the specific blocking action of picrotoxin on the effects of the FAT-M, we conclude that the FAT-M exerted its anxiolytic-like effects throughGABAAreceptor chloride channels.

Defensive burying: Effects of diazepam and oxprenolol measured in extinction

Life Sciences ◽  
1983 ◽  
Vol 33 (8) ◽  
pp. 695-699 ◽  
Author(s):  
Neville M. Blampied ◽  
Raymond C. Kirk
Keyword(s):  
Defensive Burying

scholarly journals Associative mechanisms involved in specific Pavlovian-to-instrumental transfer in human learning tasks

2018 ◽  
Vol 71 (7) ◽  
pp. 1607-1625 ◽  
Author(s):  
Daniel E Alarcón ◽  
Charlotte Bonardi ◽  
Andrew R Delamater
Keyword(s):  
Human Learning ◽  
The Other ◽  
Conditioned Stimuli ◽  
Learning Tasks ◽  
Backward Conditioning ◽  
Presence And Absence

Four experiments compared the effect of forward and backward conditioning procedures on the ability of conditioned stimuli (CS) to elevate instrumental responding in a Pavlovian-to-instrumental transfer (PIT) task. Two responses were each trained with one distinct outcome (R1->O1, R2->O2), either concurrently (Experiment 1) or separately (Experiments 2, 3 and 4). Then, in Experiments 1 and 2, four CSs were either followed or preceded by one outcome (A->O1, B->O2, O1->C, O2->D). In Experiment 3, each CS was preceded and followed by an outcome: for one group of participants, both outcomes were identical (e.g., O1->A->O1, O2->B->O2), but for the other, they were different (e.g., O1->A->O2, O2->B->O1). In Experiment 4, two CSs were preceded and followed by identical outcomes, and two CSs by different outcomes. In the PIT tests, participants performed R1 and R2 in the presence and absence of the CSs. In Experiments 1 and 2, only the CSs followed by outcomes in Pavlovian training elevated responding. In Experiments 3 and 4, all the CSs elevated responding but based on the outcome that followed them in training. These results support the stimulus-outcome-response (S-O-R) mechanism of specific PIT, according to which CSs elevate responding via activation of its associated outcome representation.

Post-Irradiation Saccharin Avoidance with Non-Coincident Stimuli

1964 ◽  
Vol 14 (2) ◽  
pp. 507-512 ◽  
Author(s):  
William A. McLaurin ◽  
John A. Farley ◽  
Barron B. Scarborough ◽  
Travis D. Rawlings
Keyword(s):  
Radiation Exposure ◽  
Avoidance Behavior ◽  
Saccharin Solution ◽  
Home Cage ◽  
Tap Water ◽  
Physiological State ◽  
Post Irradiation ◽  
Backward Conditioning ◽  
X Irradiation ◽  
Per Se

Two separate studies were made to determine the degree of post-irradiation saccharin avoidance behavior displayed by rats given tap water or no fluid to drink prior to low-level x-irradiation exposure. In neither study were significant differences, in post-treatment saccharin avoidance behavior, found between the groups receiving saccharin solution, tap water or no fluid to drink prior to radiation exposure. It was concluded that the results could be viewed as additional evidence for the hypothesis of an association of a disturbed physiological state and the discriminatory saccharin solution in the home cage and not an association of x-irradiation with saccharin solution per se. Doubt was expressed that the results could be taken as evidence for successful backward conditioning.

Differential progesterone effects on defensive burying and forced swimming tests depending upon a gradual decrease or an abrupt suppression schedules

2006 ◽  
Vol 83 (1) ◽  
pp. 130-135 ◽  
Author(s):  
Margarita Saavedra ◽  
Carlos M. Contreras ◽  
Georgina Azamar-Arizmendi ◽  
Minerva Hernández-Lozano
Keyword(s):  
Forced Swimming ◽  
Gradual Decrease ◽  
Defensive Burying

scholarly journals Backward conditioning: An artifact of experimental design?

1979 ◽  
Vol 14 (6) ◽  
pp. 431-432
Author(s):  
Cooper B. Holmes ◽  
Stephen F. Davis
Keyword(s):  
Experimental Design ◽  
Backward Conditioning
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