scholarly journals Naloxone reduces pressing for intracranial stimulation of sites in the periaqueductal gray area, accumbens nucleus, substantia nigra, and lateral hypothalamus

1979 ◽  
Vol 7 (4) ◽  
pp. 427-436 ◽  
Author(s):  
June M. Stapleton ◽  
Vicki J. Merriman ◽  
Constance L. Coogle ◽  
Steven D. Gelbard ◽  
Larry D. Reid
Keyword(s):  
Substantia Nigra ◽  
Lateral Hypothalamus ◽  
Periaqueductal Gray ◽  
Intracranial Stimulation ◽  
Gray Area ◽  
Accumbens Nucleus ◽  
Stimulation Of

Eyelid apraxia associated with deep brain stimulation of the periaqueductal gray area

2014 ◽  
Vol 21 (9) ◽  
pp. 1652-1653 ◽  
Author(s):  
Jean-Philippe Langevin ◽  
Nisaharan Srikandarajah ◽  
Scott E. Krahl ◽  
Alessandra Gorgulho ◽  
Eric Behnke ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Periaqueductal Gray ◽  
Gray Area ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals Origin of Afferent Projections into Bovine Chromaffin Cell Implants in the Rat Periaqueductal Gray Determined by Retrograde and Anterograde Tracing

1994 ◽  
Vol 5 (1) ◽  
pp. 31-48 ◽  
Author(s):  
John D. Ortega ◽  
Jacqueline Sagen ◽  
George D. Pappas
Keyword(s):  
Substantia Nigra ◽  
Lateral Hypothalamus ◽  
Chromaffin Cells ◽  
Chromaffin Cell ◽  
Cingulate Cortex ◽  
Periaqueductal Gray ◽  
Term Survival ◽  
Bovine Chromaffin Cell ◽  
Bovine Chromaffin Cells ◽  
Anterograde Tracer

We have previously described long-term survival of isolated bovine chromaffin cell suspension grafts in the periaqueductal gray of adult rats. Electron microscopic analysis of the graft sites revealed synapses on the transplanted chromaffin cells. The origin of these synapses is not known, but they are probably derived from the host since the initial grafts were suspensions of chromaffin cells that were essentially free of other cell types.In order to determine the origin of the observed synapses, retrograde and anterograde tracer analyses, were performed on grafted rats at 4 and 8 weeks after transplantation. Following injection of the retrograde tracer (Fluoro-Gold) into graft sites, four major host sites were labeled: hindbrain reticular formation, substantia nigra, lateral hypothalamus, and cingulate cortex. Injection of anterograde tracer (rhodamine-conjugated dextranamine) into the substantia nigra, lateral hypothalamus, and cingulate cortex produced labeled fibers and terminals in and around 4 and 8 week old chromaffin cell graft sites. An increase in both the number of retrogradely labeled cells, as well as in the density of anterogradely labeled fibers and terminals within the graft site, was observed from 4 to 8 weeks.This study shows that graft innervation from the host is primarily from areas that normally project afferent fibers to the periaqueductal gray. The increase in labeled fibers, and terminals over 8 weeks suggests thatde novosynapse formation on grafted bovine chromaffin cells is a continuous process that is dependent on the regenerative capacity and plasticity of the host neuronal network and the grafted bovine chromaffin cells.

STIMULATION OF THE PERIAQUEDUCTAL GRAY AREA REDUCES ANESTHETIC REQUIREMENT

1980 ◽  
Vol 53 (3 Suppl) ◽  
pp. S16-S16
Author(s):  
P. Newfield ◽  
M. F. Roizen ◽  
Y. Hosobuchi ◽  
E. I. Eger ◽  
J. E. Adams ◽  
...  
Keyword(s):  
Periaqueductal Gray ◽  
Gray Area ◽  
Anesthetic Requirement ◽  
Stimulation Of
Sign in / Sign up

Export Citation Format

Share Document