scholarly journals Postural Sway in Patients with Parkinson Disease. Learning and Evaluation with Neural Networks.

1998 ◽  
Vol 57 (4) ◽  
pp. 413-420
Author(s):  
Mitsuhiro Mori ◽  
Takashi Tokita ◽  
Tsuyoshi Okawa ◽  
Yasunari Shibata ◽  
Hideo Miyata
1998 ◽  
Vol 57 (3) ◽  
pp. 271-279 ◽  
Author(s):  
Mitsuhiro Mori ◽  
Takashi Tokita ◽  
Tsuyoshi Okawa ◽  
Yasunari Shibata ◽  
Hideo Miyata

1998 ◽  
Vol 57 (6) ◽  
pp. 556-565
Author(s):  
Mitsuhiro Mori ◽  
Takashi Tokita ◽  
Tsuyoshi Okawa ◽  
Yasunari Shibata ◽  
Hideo Miyata

2016 ◽  
Vol 96 (9) ◽  
pp. 1364-1371 ◽  
Author(s):  
Fay B. Horak ◽  
Martina Mancini ◽  
Patricia Carlson-Kuhta ◽  
John G. Nutt ◽  
Arash Salarian

Abstract Background The Instrumented Stand and Walk (ISAW) test, which includes 30 seconds of stance, step initiation, gait, and turning, results in many objective balance and gait metrics from body-worn inertial sensors. However, it is not clear which metrics provide independent information about mobility. Objective It was hypothesized that balance and gait represent several independent domains of mobility and that not all domains would be abnormal in individuals with Parkinson disease (PD) or would change with levodopa therapy. Design This was a cross-sectional study. Methods A factor analysis approach was used to identify independent measures of mobility extracted from the ISAW in 100 participants with PD and 21 control participants. First, a covariance analysis showed that postural sway measures were independent of gait measures. Then, the factor analysis revealed 6 independent factors (mobility domains: sway area, sway frequency, arm swing asymmetry, trunk motion during gait, gait speed, and cadence) that accounted for 87% of the variance of performance across participants. Results Sway area, gait speed, and trunk motion differed between the PD group in the off-levodopa state and the control group, but sway frequency (but not sway area) differed between the PD group in the off-levodopa state and the control group. Four of the 6 factors changed significantly with levodopa (off to on): sway area, sway frequency, trunk motion during gait, and cadence. When participants were on levodopa, the sway area increased compared with off levodopa, becoming more abnormal, whereas the other 3 significant metrics moved toward, but did not reach, the healthy control values. Limitations Exploratory factor analysis was limited to the PD population. Conclusions The different sensitivity various balance and gait domains to PD and to levodopa also support neural control of at least 6 independent mobility domains, each of which warrants clinical assessment for impairments in mobility.


2016 ◽  
Vol 37 (12) ◽  
pp. 4500-4510 ◽  
Author(s):  
S. Nigro ◽  
R. Riccelli ◽  
L. Passamonti ◽  
G. Arabia ◽  
M. Morelli ◽  
...  

2018 ◽  
Vol 43 (2) ◽  
pp. 147-154 ◽  
Author(s):  
Connie L. Fiems ◽  
Eric L. Dugan ◽  
Elizabeth S. Moore ◽  
Stephanie A. Combs-Miller

2009 ◽  
Vol 89 (2) ◽  
pp. 162-168 ◽  
Author(s):  
Gabriele Wulf ◽  
Merrill Landers ◽  
Rebecca Lewthwaite ◽  
Thomas Toöllner

BackgroundPostural instability while standing, walking, and interacting with objects or the environment places individuals with Parkinson disease (PD) at risk for falls, injuries, and self-imposed restrictions in activity. Recent research with motor skills, including those demanding postural stability, has demonstrated performance and learning advantages when performers are instructed to adopt an external rather than an internal focus of attention. Despite the potential benefits in stability-related risk reduction and enhanced movement effectiveness, attentional focus research in individuals challenged with postural instability is limited.ObjectiveThe present translational research study examined the generalizability of the attentional focus effect to balance in older adults with PD.DesignA within-participant design was used to account for potentially substantial individual variations in balancing capabilities.MethodsFourteen participants diagnosed with idiopathic PD (Hoehn and Yahr stages II and III) participated in the experiment. They were asked to balance on an unstable surface (inflated rubber disk). In counterbalanced orders, they were instructed to focus on reducing movements of their feet (internal focus) or the disk (external focus), or they were not given attentional focus instructions (control).ResultsThe adoption of an external focus resulted in less postural sway relative to both internal focus and control conditions. There was no difference between the internal focus and control conditions.LimitationsMental functioning was not formally assessed, and comprehensive clinical profiles of participants were not obtained.ConclusionsThe results are consistent with previous findings on attentional focus in samples of patients and people without disabilities. Subtle wording distinctions that direct attention to movement effects external to the mover reduce postural instability during standing for individuals with PD relative to an internal focus. The findings have potentially important implications for instructions given by clinicians and the reduction of fall risk.


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