scholarly journals HIV-positive MSM’s knowledge of HPV and anal cancer self-sampling: A scoping review

2018 ◽  
Vol 25 (1) ◽  
pp. 83 ◽  
Author(s):  
M.K.L. Poon ◽  
J.P.H. Wong ◽  
A.T.W. Li ◽  
M. Manuba ◽  
A. Bisignano ◽  
...  
Keyword(s):  
Anal Cancer ◽  
Scoping Review ◽  
Cancer Education ◽  
Hpv Vaccination ◽  
Cell Cancer ◽  
Hpv Infection ◽  
Hiv Positive ◽  
Policy Makers ◽  
High Prevalence ◽  
Sex With Men

Human papillomavirus (hpv) infection is the cause of anal squamous cell cancer (ascc) in 80% of cases. Available research has also shown high prevalence of anal hpv infection among men who have sex with men (msm). However, hpv vaccination is low among msm in Canada. In light of this information, we conducted a scoping review with the aim of exploring (1) the knowledge of hpv and anal cancer among hiv-positive msm and (2) the acceptability of hpv and anal cancer self-sampling in this population. In conducting the review, we searched five electronic databases for peer-reviewed articles and abstracts published in English, between 2007 and 2017. A total of 803 articles were retrieved; after accounting for duplicates (n=40) and unmet criteria (n=754), a total of 794 articles were excluded. A final total of nine articles were used in this review. Results of this review show that hiv-positive msm have limited knowledge regarding the risks of anal cancer associated with hiv and hpv coinfection. Furthermore, there is limited research on hpv and anal cancer self-sampling in this population. However, the review of available studies suggested that hiv-positive msm were open to anal cancer self-sampling. It also identified potential barriers to self-sampling. In conclusion, we provide suggestions and future directions for policy-makers and educators to develop inclusive and accessible strategies to reach hiv-positive msm regarding anal cancer education and self-screening.

scholarly journals Long-Term outcomes of Hpv Vaccination In Prevention of Anal Cancer In older Hiv-Positive Men Who Have Sex With Men

2015 ◽  
Vol 18 (3) ◽  
pp. A206
Author(s):  
A.A. Deshmukh ◽  
J. Chhatwal ◽  
E.Y. Chiao ◽  
A.G. Nyitray ◽  
P. Das ◽  
...  
Keyword(s):  
Anal Cancer ◽  
Hpv Vaccination ◽  
Hiv Positive ◽  
Long Term Outcomes ◽  
Sex With Men ◽  
Hiv Positive Men

scholarly journals HPV Infection in Men

2007 ◽  
Vol 23 (4) ◽  
pp. 261-272 ◽  
Author(s):  
Joel M. Palefsky
Keyword(s):  
Natural History ◽  
Hpv Vaccination ◽  
Intraepithelial Neoplasia ◽  
Visual Assessment ◽  
Hpv Infection ◽  
Hiv Positive ◽  
History Of ◽  
Sex With Men ◽  
The Impact ◽  
Cervical Human Papillomavirus

While much is known about the natural history of cervical human papillomavirus (HPV) infection and its consequences, including cervical intraepithelial neoplasia and cervical cancer, relatively little is known about the natural history of anogenital HPV infection and diseases in men. In part this reflects difficulties in penile sampling and visual assessment of penile lesions. Anal HPV infection and disease also remain poorly understood. Although HPV is transmitted sexually and infects the genitals of both sexes, the cervix remains biologically more vulnerable to malignant transformation than does the penis or anus in men. An understanding of male HPV infection is therefore important in terms of reducing transmission of HPV to women and improving women's health. However, it is also important due to the burden of disease in men, who may develop both penile and anal cancer, particularly among HIV-positive men who have sex with men. Improved sampling techniques of the male genitalia and cohort studies in progress should provide important information on the natural history of anogenital HPV infection and disease in men, including risk factors for HPV acquisition and transmission. The impact of HPV vaccination in women on male anogenital HPV infection will also need to be assessed.

scholarly journals Adjuvant HPV vaccination for anal cancer prevention in HIV-positive men who have sex with men: The time is now

Vaccine ◽  
2017 ◽  
Vol 35 (38) ◽  
pp. 5102-5109 ◽  
Author(s):  
Ashish A. Deshmukh ◽  
Scott B. Cantor ◽  
Elisabeth Fenwick ◽  
Elizabeth Y. Chiao ◽  
Alan G. Nyitray ◽  
...  
Keyword(s):  
Cancer Prevention ◽  
Anal Cancer ◽  
Hpv Vaccination ◽  
Hiv Positive ◽  
Sex With Men ◽  
Hiv Positive Men

Vroegtijdige opsporing van voorstadia van een anaal carcinoom bij hiv-seropositieve patiënten

2021 ◽  
Author(s):  
E. GÖKCE ◽  
J. GELDOF ◽  
P. ROELANDT ◽  
J. VAN DORPE ◽  
S. CALLENS ◽  
...  
Keyword(s):  
Anal Cancer ◽  
Digital Rectal Examination ◽  
Intraepithelial Neoplasia ◽  
Hpv Infection ◽  
High Grade ◽  
Anal Squamous Cell Carcinoma ◽  
Increased Risk ◽  
High Prevalence ◽  
Risk Patients ◽  
Hiv Seropositive

Early detection of precursor lesions of anal cancer in HIV-seropositive patients Although anal cancer is rare in the overall population, its incidence is increasing in the last decades. Especially HIV-seropositive patients have an increased risk of developing anal squamous cell carcinoma (SCC), mainly because of the high prevalence of high-grade anal intraepithelial neoplasia (AIN) among these patients. High-grade AIN is a precursor lesion for anal SCC associated with human papillomavirus (HPV) infection. Despite the lack of direct evidence demonstrating that AIN identification reduces the risk of anal cancer, experts think that screening and treatment of high-risk patients will prevent the disease. This article aims to review the current literature about AIN and discusses the screening options, including digital rectal examination, anal cytology and high-resolution anoscopy.

Prevalence of human papillomavirus by geographical regions, sexual orientation and HIV status in China: a systematic review and meta-analysis

2018 ◽  
Vol 94 (6) ◽  
pp. 434-442 ◽  
Author(s):  
Xiaomeng Ma ◽  
Qian Wang ◽  
Jason J Ong ◽  
Christopher K Fairley ◽  
Shu Su ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Meta Analysis ◽  
Hpv Vaccination ◽  
Hpv Infection ◽  
Central China ◽  
Hiv Positive ◽  
Heterosexual Men ◽  
Hpv Prevalence

ObjectiveHuman papillomavirus (HPV) infection causes multiple cancers in both women and men. In China, both HPV vaccination and cervical cancer screening coverages are low. We aim to investigate the temporal and geographical trends of HPV DNA prevalence in heterosexual men, women, men who have sex with men (MSM) and people living with HIV (PLHIV) in China.MethodsWe conducted a systematic review, collecting publications in PubMed, Web of Science, China National Knowledge Infrastructure (CNKI) and Wanfang Data from January 2000 to May 2017. A total of 247 studies were selected for this meta-analysis to estimate pooled HPV prevalence, incidence of cervical cancer and risk of infection for subgroups. Meta-regression was applied to identify contributing factors to prevalence heterogeneities.ResultsThe national HPV prevalence was 15.6% (95% CI (14.4% to 16.9%)) in women with normal cervical cytology, and Central China had the highest prevalence (20.5% (15.2% to 25.8%)). HPV prevalence in heterosexual men (14.5% (11.3% to 17.7%)) was comparable with that of women (OR=1.09 (0.98 to 1.17)), but HPV prevalence in MSM (59.9% (52.2% to 67.6%)) was significantly higher than that in heterosexual men (OR=8.81 (8.01 to 9.69)). HIV-positive women (45.0% (38.4% to 51.6%)) and HIV-positive MSM (87.5% (82.3% to 90.9%)) had 4.67 (3.61 to 6.03) and 6.46 (5.20 to 8.02) times higher risk of HPV infection than their HIV negative counterparts.ConclusionHPV infection is prevalent in China, particularly in Central China, in comparison with the global level and neighbouring countries. Targeted HPV vaccination for women, MSM and PLHIV and scale-up of cervical screening for women are priorities in curbing the HPV epidemic in China.

Prevalence and risk factors of anogenital human papillomavirus infection in a community sample of men who have sex with men in Taiwan: baseline findings from a cohort study

2019 ◽  
Vol 96 (1) ◽  
pp. 62-66
Author(s):  
Carol Strong ◽  
Huachun Zou ◽  
Nai-Ying Ko ◽  
Ya-Lun Liang ◽  
Wen-Wei Ku ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Cost Effectiveness ◽  
Community Sample ◽  
Hpv Vaccination ◽  
Hpv Infection ◽  
Sex Partners ◽  
Anal Sex ◽  
The Past ◽  
Sex With Men

ObjectivesMen who have sex with men (MSM) are a highly neglected population in the current recommendation of girls-only human papillomavirus (HPV) vaccination programmes in many countries. To better assess the cost effectiveness of HPV vaccination among men requires data on the prevalence of HPV infection in MSM using a community sample, which is still sparse in several regions. We examined the prevalence of and factors associated with anogenital HPV infection among MSM in Taiwan.MethodsMSM 20 years of age and older were recruited from the community and social media in Taiwan in 2015–2016 and screened for HPV infection to detect 37 genotypes. MSM were seen at baseline and were/will be seen at 6, 12, 24 and 36 months. Men completed a questionnaire regarding their sexual experiences. Multivariable regression analyses were conducted to identify associated behavioural risk factors using the baseline data.ResultsA total of 253 MSM were recruited; 87 % were below 35 years of age. Diagnosis of HIV was reported in 4% of men; just over 20% had three or more anal sex partners in the past year. The prevalence of any tested HPV type was 29.4% at the anal site and 11% at the penile site. One quarter of MSM were infected with any of the 9-valent vaccine HPV types. Anal HPV detection was associated with having three or more receptive anal sex partners in the past year (adjusted odds ratio (aOR)=2.92, 95% CI 1.29 to 6.61) and having older sex partners (aOR=2.51, 95% CI 1.07 to 5.90).ConclusionsOur data provide the base to calculate the reproductive rate for HPV transmission in a low-risk community sample and cost-effectiveness to include men in HPV vaccination policies. Adding evidence from a community sample adds comprehensiveness for future estimates of disease transmission and vaccine effectiveness.

Prevalence of oral human papillomavirus in men attending an Italian sexual health clinic

Sexual Health ◽  
2016 ◽  
Vol 13 (6) ◽  
pp. 597 ◽  
Author(s):  
Francesco Drago ◽  
Astrid Herzum ◽  
Giulia Ciccarese ◽  
Roberto Bandelloni
Keyword(s):  
Human Papillomavirus ◽  
Hpv Infection ◽  
Health Clinic ◽  
High Risk Population ◽  
Hpv Dna ◽  
Hpv Prevalence ◽  
Sexually Transmissible Infections ◽  
High Prevalence ◽  
Oral Hpv ◽  
Sex With Men

A high-risk population, formed by 79 consecutive male attendees of our sexually transmissible infections clinic, and who did not have any overt signs of human papillomavirus (HPV) infection, were examined. Oral HPV prevalence (37%) was much higher than previously reported. Periurethral HPV-DNA was found in 49% of the patients and anal HPV-DNA was found in 43% of the patients. Considering the high prevalence of oral HPV obtained in the current study, it is important to further investigate the burden of oral HPV, not only in men who have sex with men, but also in heterosexual men and in women.

4. High prevalence of anal HPV infection among HIV-positive male subjects in the absence of anal intercourse

Sexual Health ◽  
2013 ◽  
Vol 10 (6) ◽  
pp. 571
Author(s):  
Eugenio Nelson Cavallari ◽  
Gabriella d'Ettorre ◽  
Giancarlo Ceccarelli ◽  
Sara Serafini ◽  
Alessandra Pierangeli ◽  
...  
Keyword(s):  
Anal Cancer ◽  
Injection Drug Users ◽  
Anal Intercourse ◽  
Hpv Infection ◽  
Hiv Positive ◽  
Receptive Anal Intercourse ◽  
Cross Sectional ◽  
Hpv Dna ◽  
Significant Difference ◽  
History Of

Background The risk of progression to cancer from HPV infection is increased in HIV-positive subjects. Anal HPV infection is a concern among men who have sex with men (MSM), especially in the setting of HIV infection. Methods: Cross-sectional study including 62 HIV-positive injection drug users (IDUs) without history of receptive anal intercourse and 110 HIV-positive MSM. All patients were receiving HAART with HIV-RNA <37 copies/mL. Patients answered a self-administered questionnaire investigating their sexual habits. Participants underwent anal brushing collecting samples for cytology examination (Bethesda 2001 criteria for cervical cytology) and high resolution anoscopy collecting samples for histological classification. HPV-DNA polymerase chain reaction (PCR) identification was performed. Results: Of the IDUs, 62.5% showed CD4 nadir <200 cell/mmc compared with 12% of MSM (P < 0.05), the actual CD4+ T-cells count did not show a statistical difference. HPV-DNA PCR tested positive in 52% of IDUs and 69% of MSM (P < 0.05). Presence of high-risk genotypes did not show significant difference between the groups (38% of IDUs and 31% of MSM). LSIL prevalence was higher among MSM than IDUs (38% v. 23%), HSIL was higher among IDUs than MSM (26% v. 21%). The prevalence of anal cancer was similar in the two populations (3% in each group). All patients, except for men presenting with anal cancer, were completely asymptomatic. Conclusions: Anal HPV infection and anal SIL may be acquired in the absence of anal intercourse in HIV-infected men. The prevalence of HSIL is high among HIV-positive IDUs. All HIV-infected men, regardless of history of anal intercourse, should be considered for anal cytology screening.

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