Protective effects of Chinese herbal medicine Zuogui Pill on retina ganglion cells after optical nerve clipping injury in rats

2011 ◽  
Vol 9 (9) ◽  
pp. 991-997 ◽  
Author(s):  
YQ Wang
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Ganglion Cells ◽  
Protective Effects ◽  
Chinese Herbal ◽  
Zuogui Pill

scholarly journals Protective Effects ofDracocephalum heterophyllumin ConA-Induced Acute Hepatitis

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Wei Zheng ◽  
Qilan Wang ◽  
Xiaohua Lu ◽  
Qiangqiang Shi ◽  
Junhui Zou ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Herbal Medicine ◽  
Liver Injury ◽  
Chinese Herbal Medicine ◽  
Tumor Necrosis ◽  
Suppressor Cells ◽  
Myeloid Derived Suppressor Cells ◽  
Protective Effects ◽  
Chinese Herbal ◽  
Necrosis Factor

Dracocephalum heterophyllum(DH) is a Chinese herbal medicine used in treating hepatitis. However, the protective effects and pharmacological mechanisms of DH in hepatitis are unknown. In this study, we found that pretreatment with DH extract significantly ameliorated liver injury and suppressed the production of inflammatory cytokines, including tumor necrosis factor (TNF-α) and interferon-γ(IFN-γ) in Concanavalin A- (ConA-) induced hepatitis (CIH). DH recruited more CD11b+Gr1+myeloid-derived suppressor cells (MDSCs) to the liver and suppressed infiltration of macrophages (Kupffer cells) in the liver. The present work explores DH as an effective hepatoprotective medicine to inhibit inflammation and liver injury caused by hepatitis.

scholarly journals Chinese Herbal Medicine for Myelosuppression Induced by Chemotherapy or Radiotherapy: A Systematic Review of Randomized Controlled Trials

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Youji Jia ◽  
Huihui Du ◽  
Min Yao ◽  
Xuejun Cui ◽  
Qi Shi ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Randomized Controlled Trials ◽  
Chinese Herbal Medicine ◽  
Blood Cells ◽  
White Blood Cells ◽  
Small Sample ◽  
Controlled Trials ◽  
Protective Effects ◽  
Randomized Controlled ◽  
Chinese Herbal

Background. Myelosuppression is one of the major side effects of chemo- and radiotherapy in cancer patients and there are no effective interventions to prevent it currently. Chinese herbal medicine (CHM) may be helpful due to its multidrug targets.Objectives.This study was designed to evaluate effectiveness of CHM on preventing patients from experiencing myelosuppression by chemo- or radiotherapy.Search Methods.Randomized controlled trials (RCTs) were retrieved from seven different databases from the date of database creation to April 2014. We assessed all included studies using Cochrane Handbook for Systematic Reviews of Interventions 5.1.0 and performed statistical analysis using RevMan 5.2.1.Results. Eight RCTs were included (818 patients). Pooled data showed that increase of white blood cells (WBCs) is higher with CHM plus chemotherapy/radiotherapy than with chemotherapy/radiotherapy only. Both CHM compared to placebo and CHM combined with chemotherapy/radiotherapy compared to chemotherapy/radiotherapy lacked significant differences in the peripheral platelets, red blood cells (RBCs), and hemoglobin changes.Conclusions.Our results demonstrated that CHM significantly protected peripheral blood WBCs from a decrease caused by chemotherapy or radiotherapy. There were no significant protective effects on peripheral RBCs, hemoglobin, or platelets, which may be related to low quality and small sample of included studies.

scholarly journals Antagonistic Effects of Tetramethylpyrazine on Hypoxic Respiratory Depression in Rats

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Li Li ◽  
Bo Gao ◽  
Meifang Liu ◽  
Manel Santafe
Keyword(s):  
Herbal Medicine ◽  
Protein Expression ◽  
Respiratory Depression ◽  
Chinese Herbal Medicine ◽  
Protective Effects ◽  
Antagonistic Effects ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Hypoxia Treatment ◽  
Respiratory Responses

Objective. Tetramethylpyrazine (TMP) is an alkaloid extracted from the root and stem of the traditional Chinese herbal medicine called Chuanxiong. The present study aims to study the effects of TMP on hypoxic respiratory depression in rats. Materials and methods. The effects of TMP on respiratory responses of rats induced by hypoxia were observed by diaphragm electromyogram (EMG) recording. The effects of TMP on the protein expression of FOS and acid sensing ion channel1a (ASIC1a) in the brainstem induced by hypoxia were investigated by immunohistochemistry. Results. The respiration of rats was first excited and then depressed during hypoxia treatment, while TMP pretreatment could significantly antagonize the respiratory depression induced by hypoxia P < 0.01 . Hypoxia obviously induced the protein expression of FOS P < 0.01 and ASIC1a P < 0.05 in the brainstem, which can be also significantly inhibited by TMP pretreatment. Conclusions. TMP has protective effects on hypoxic respiratory depression, and the mechanisms might be concerned with its downregulation of FOS and ASIC1a in the brainstem induced by hypoxia.

The effect of the chinese herbal medicine Dai-Kenchu-To on intestinal blood flow

2001 ◽  
Vol 120 (5) ◽  
pp. A248-A248
Author(s):  
N KAWASAKI ◽  
K NARIAI ◽  
M NAKAO ◽  
K NAKADA ◽  
N HANYUU ◽  
...  
Keyword(s):  
Blood Flow ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Intestinal Blood Flow ◽  
Chinese Herbal
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