scholarly journals Antagonistic Effects of Tetramethylpyrazine on Hypoxic Respiratory Depression in Rats

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Li Li ◽  
Bo Gao ◽  
Meifang Liu ◽  
Manel Santafe
Keyword(s):  
Herbal Medicine ◽  
Protein Expression ◽  
Respiratory Depression ◽  
Chinese Herbal Medicine ◽  
Protective Effects ◽  
Antagonistic Effects ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Hypoxia Treatment ◽  
Respiratory Responses

Objective. Tetramethylpyrazine (TMP) is an alkaloid extracted from the root and stem of the traditional Chinese herbal medicine called Chuanxiong. The present study aims to study the effects of TMP on hypoxic respiratory depression in rats. Materials and methods. The effects of TMP on respiratory responses of rats induced by hypoxia were observed by diaphragm electromyogram (EMG) recording. The effects of TMP on the protein expression of FOS and acid sensing ion channel1a (ASIC1a) in the brainstem induced by hypoxia were investigated by immunohistochemistry. Results. The respiration of rats was first excited and then depressed during hypoxia treatment, while TMP pretreatment could significantly antagonize the respiratory depression induced by hypoxia P < 0.01 . Hypoxia obviously induced the protein expression of FOS P < 0.01 and ASIC1a P < 0.05 in the brainstem, which can be also significantly inhibited by TMP pretreatment. Conclusions. TMP has protective effects on hypoxic respiratory depression, and the mechanisms might be concerned with its downregulation of FOS and ASIC1a in the brainstem induced by hypoxia.

Study of the ESI and APCI interfaces for the UPLC–MS/MS analysis of pesticides in traditional Chinese herbal medicine

2013 ◽  
Vol 406 (5) ◽  
pp. 1481-1491 ◽  
Author(s):  
Lina Chen ◽  
Fengrui Song ◽  
Zhiqiang Liu ◽  
Zhong Zheng ◽  
Junpeng Xing ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Ms Analysis

scholarly journals In defence of traditional Chinese herbal medicine

Anaesthesia ◽  
2003 ◽  
Vol 58 (3) ◽  
pp. 282-283 ◽  
Author(s):  
I. Hosbach ◽  
G. Neeb ◽  
S. Hager ◽  
S. Kirchhoff ◽  
B. Kirschbaum
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal

scholarly journals In vivo Anti-candidal Activity Induced by a Traditional Chinese Herbal Medicine, Ganoderma lucidum.

1992 ◽  
Vol 33 (4) ◽  
pp. 505-512
Author(s):  
Hour-Young Chen ◽  
Chien-Ho Chen ◽  
Min-Yang Yeh ◽  
Jau-Shin Wu ◽  
Katsukiyo Yazawa ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Ganoderma Lucidum ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal

scholarly journals Survival Benefit of Traditional Chinese Herbal Medicine (A Herbal Formula for Invigorating Spleen) in Gastric Cancer Patients with Peritoneal Metastasis

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Lu Zhao ◽  
Ai-Guang Zhao ◽  
Gang Zhao ◽  
Yan Xu ◽  
Xiao-Hong Zhu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Herbal Medicine ◽  
Cancer Patients ◽  
Chinese Herbal Medicine ◽  
Peritoneal Metastasis ◽  
Herbal Formula ◽  
First Line ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal ◽  
Gastric Cancer Patients

Objective.We evaluated the efficiency of traditional Chinese herbal medicine (a compound herbal formula for invigorating spleen) as a complementary and alternative therapy for gastric cancer patients with peritoneal metastasis.Methods.Between 2001 and 2012, 93 gastric cancer patients with peritoneal metastasis were enrolled in this study. The effect of traditional Chinese herbal medicine on their long-term outcome was investigated. Kaplan-Meier method was used to assess the difference in survival time, and Cox proportional hazards regression analysis was performed to identify independent prognostic factors.Result.First-line palliative chemotherapy plus traditional Chinese herbal medicine was performed in 47 patients and the other 46 patients received chemotherapy alone. The overall survival was different between patients with and without traditional Chinese herbal medicine (12.0 versus 10.5 months;P=0.046). According to the Cox proportional hazard model, first-line chemotherapy cycle (hazards ratio [HR] = 0.527; 95% CI = 0.323~0.860) and TCHM (hazards ratio [HR] = 0.644; 95% CI = 0.481~0.992) were selected as independent prognostic factors for survival.Conclusion.The results suggest that traditional Chinese herbal medicine could improve the prognosis of the gastric cancer patients with peritoneal metastasis.

Shengmai (a traditional Chinese herbal medicine) for heart failure

2014 ◽  
Author(s):  
Qin Zhou ◽  
Wen-Zhe Qin ◽  
Shuai-Bin Liu ◽  
Joey SW Kwong ◽  
Jing Zhou ◽  
...  
Keyword(s):  
Heart Failure ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Traditional Chinese Herbal Medicine ◽  
Chinese Herbal
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