Correlation between cognitive functions and syndromes of traditional Chinese medicine in amnestic mild cognitive impairment

2009 ◽  
Vol 7 (3) ◽  
pp. 205-211 ◽  
Author(s):  
YC Miao
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Cognitive Functions ◽  
Amnestic Mild Cognitive Impairment

P2-091: Tomm40 ‘523’ polymorphisms may influence cognitive functions in patients with amnestic mild cognitive impairment

2015 ◽  
Vol 11 (7S_Part_11) ◽  
pp. P519-P519
Author(s):  
Ivana Mokrisova ◽  
Jan Laczó ◽  
Martina Parizkova ◽  
Kamil Vlček ◽  
Martin Vyhnalek ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Functions ◽  
Amnestic Mild Cognitive Impairment

Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment

2020 ◽  
Vol 73 (1) ◽  
pp. 247-257 ◽  
Author(s):  
Katerina Cechova ◽  
Ross Andel ◽  
Francesco Angelucci ◽  
Zuzana Chmatalova ◽  
Hana Markova ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Functions ◽  
Gene Polymorphisms ◽  
Amnestic Mild Cognitive Impairment

scholarly journals Cortical Source Multivariate EEG Synchronization Analysis on Amnestic Mild Cognitive Impairment in Type 2 Diabetes

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Dong Cui ◽  
Jing Liu ◽  
Zhijie Bian ◽  
Qiuli Li ◽  
Lei Wang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Functions ◽  
Amnestic Mild Cognitive Impairment ◽  
Control Group ◽  
Synchronization Index ◽  
Amci Group ◽  
And Control

Is synchronization altered in amnestic mild cognitive impairment (aMCI) and normal cognitive functions subjects in type 2 diabetes mellitus (T2DM)? Resting eye-closed EEG data were recorded in 8 aMCI subjects and 11 age-matched controls in T2DM. Three multivariate synchronization algorithms (S-estimator (S), synchronization index (SI), and global synchronization index (GSI)) were used to measure the synchronization in five ROIs of sLORETA sources for seven bands. Results showed that aMCI group had lower synchronization values than control groups in parietal delta and beta2 bands, temporal delta and beta2 bands, and occipital theta and beta2 bands significantly. Temporal (r=0.629;P=0.004) and occipital (r=0.648;P=0.003) thetaSvalues were significantly positive correlated with Boston Name Testing. In sum, each of methods reflected that the cortical source synchronization was significantly different between aMCI and control group, and these difference correlated with cognitive functions.

scholarly journals A Two-Year Treatment of Amnestic Mild Cognitive Impairment using a Compound Chinese Medicine: A Placebo Controlled Randomized Trial

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Junying Zhang ◽  
Zhen Liu ◽  
Huamin Zhang ◽  
Caishui Yang ◽  
He Li ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Placebo Group ◽  
Mild Cognitive Impairment ◽  
Chinese Medicine ◽  
Episodic Memory ◽  
Goodness Of Fit ◽  
Amnestic Mild Cognitive Impairment ◽  
Drug Group ◽  
Therapeutic Effects ◽  
Global Connectivity

Abstract We aimed to investigate the long-term therapeutic effects of a compound Chinese medicine, the Bushen capsule, on cognition and brain connectivity in patients with amnestic mild cognitive impairment (aMCI). Thus, sixty aMCI participants were recruited to this 24-month study and were randomly divided into treatment (30 with a Bushen capsule) and placebo (30 with a placebo capsule) groups. Neuropsychological tests with MMSE and episodic memory as the primary outcomes and resting-state functional magnetic resonance imaging (fMRI) were analyzed before and after the treatment over 24 month period. In contrast to the placebo group, the drug group presented improved or stable general cognitive function, memory, language and executive function especially the primary outcomes MMSE and episodic memory with Bushen capsule treatment. FMRI results showed increased connectivity in the right precuneus and the global connectivity indexed with goodness of fit (GOF) of the default mode network (DMN) in the drug group and decreased GOF in the placebo group. More importantly, we found the GOF change was positively correlated with changes in MMSE and memory scores after 24 months in the drug group. Over 24 months, treatment with the compound Chinese medicine Bushen capsule can improve multiple domains of cognition and increase the functional local (right precuneus) and global connectivity within the DMN, which are associated with better performance.

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