scholarly journals Recurrence Rates and Mesh Shrinkage After Polypropylene vs. Polyester Mesh Hernia Repair in Complicated Hernias

2018 ◽  
Vol 55 (1) ◽  
pp. 79-81 ◽  
Author(s):  
Bogdan Socea ◽  
Laura Ileana Socea ◽  
Ovidiu Gabriel Bratu ◽  
Bogdan Mastalier ◽  
Mihai Dimitriu ◽  
...  
Keyword(s):  
Hernia Repair ◽  
Polypropylene Mesh ◽  
Chemical Structure ◽  
Abdominal Hernia ◽  
Recurrence Rates ◽  
Anatomic Repair ◽  
Mesh Shrinkage ◽  
Mesh Material ◽  
Mesh Hernia Repair ◽  
Materials Used

Prosthetic mesh implants in hernia repair are frequently used based on the fact that lower recurrence rates are detected compared to anatomic repair. In latest years, researchers tried to answer weather there is an ideal mesh material for abdominal hernia repair. The studies tried to compare resistance, bio-tolerance, rates of recurrence and infection of several materials used in alloplasty. The results are far from pointing an unique ideal chemical structure of mesh. In our study, we compared the results of a cohort of 265 patients operated in 2010 and 2011 in our clinic for complicated abdominal incisional hernias. We compared the results of polypropylene mesh vs. polyester. Polypropylene mesh proved significantly better for preventing hernia recurrence and showed a lower shrinkage rate.

Intraperitoneal Polypropylene Mesh Hernia Repair Complicates Subsequent Abdominal Surgery

2006 ◽  
Vol 31 (2) ◽  
pp. 423-429 ◽  
Author(s):  
J. A. Halm ◽  
L. L. de Wall ◽  
E. W. Steyerberg ◽  
J. Jeekel ◽  
J. F. Lange
Keyword(s):  
Abdominal Surgery ◽  
Hernia Repair ◽  
Polypropylene Mesh ◽  
Mesh Hernia Repair

scholarly journals ROBOTIC RETRO RECTUS MESH REPAIR OF VENTRAL ABDOMINAL HERNIA – AN INSTITUTIONAL EXPERIENCE

2021 ◽  
pp. 1-3
Author(s):  
Arundev R ◽  
Durga Sowmya S ◽  
Farhanul Huda
Keyword(s):  
Minimally Invasive ◽  
Hernia Repair ◽  
Ventral Hernia ◽  
Polypropylene Mesh ◽  
Average Length ◽  
Abdominal Hernia ◽  
Invasive Technique ◽  
Robot Assisted ◽  
Mesh Placement ◽  
Early Return

Ventral hernia is a common condition treated by general surgeons. Open ventral mesh hernia repair has been in practice; the high failure rates have led to the rise of minimally invasive techniques. The da Vinci robot-assisted repair is a minimally invasive technique that provides an advantage of three-dimensional imaging, precise suturing, and dissection at difficult angles. In this study, we share our experience of robot assisted retro rectus ventral hernia repair (RRVH) in four patients. Retro rectus mesh placement has the advantage of fewer chances of exposure of the mesh and a low operative cost, as polypropylene mesh can be used. Of the four patients, 3 were females, and one was male with a mean age of 46.5±6.5 SD. The mean operative time was 175±28.7 minutes for skin-to-skin completion and 151.25 ± 26.07 minutes for console duration. There were no intra-operative complications. Post-operatively, the average pain score on the day of surgery was 1.75±0.43 SD (on a scale from 0 to 10) and on the first postoperative day was 0.5 ± 0.5 SD. The average length of hospital stay was 2.25±0.43 SD days. None of the patients had seroma, surgical site infection, adhesive bowel obstruction, or recurrence of hernia on one month and six months follow up. RRVH has an advantage regarding the decreased postoperative pain and early return to daily activities. This technique promotes the usage of polypropylene mesh, which reduces the cost of surgery.

scholarly journals Biopolymeric Materials Used as Nonviral Vectors: A Review

2021 ◽  
Vol 2 (1) ◽  
pp. 100-109
Author(s):  
Jailson de Araújo Santos ◽  
Daniel Barbosa Liarte ◽  
Alessandra Braga Ribeiro ◽  
Marcia dos Santos Rizzo ◽  
Marcília Pinheiro da Costa ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Web Of Science ◽  
Gene Transfection ◽  
Genetic Material ◽  
Nonviral Vectors ◽  
Cationic Polymers ◽  
Genetic Trait ◽  
Low Diversity ◽  
Different Types ◽  
Materials Used

Bacterial transformation and gene transfection can be understood as being the results of introducing specific genetic material into cells, resulting in gene expression, and adding a new genetic trait to the host cell. Many studies have been carried out to investigate different types of lipids and cationic polymers as promising nonviral vectors for DNA transfer. The present study aimed to carry out a systematic review on the use of biopolymeric materials as nonviral vectors. The methodology was carried out based on searches of scientific articles and applications for patents published or deposited from 2006 to 2020 in different databases for patents (EPO, USPTO, and INPI) and articles (Scopus, Web of Science, and Scielo). The results showed that there are some deposits of patents regarding the use of chitosan as a gene carrier. The 16 analyzed articles allowed us to infer that the use of biopolymers as nonviral vectors is limited due to the low diversity of biopolymers used for these purposes. It was also observed that the use of different materials as nonviral vectors is based on chemical structure modifications of the material, mainly by the addition of cationic groups. Thus, the use of biopolymers as nonviral vectors is still limited to only a few polysaccharide types, emphasizing the need for further studies involving the use of different biopolymers in processes of gene transfer.

scholarly journals Slowly resorbable biosynthetic mesh: 2-year results in VHWG grade 3 hernia repair

Hernia ◽  
2021 ◽  
Author(s):  
M. M. J. Van Rooijen ◽  
T. Tollens ◽  
L. N. Jørgensen ◽  
T. S. de Vries Reilingh ◽  
G. Piessen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hernia Repair ◽  
Hernia Recurrence ◽  
Recurrence Rates ◽  
Elective Repair ◽  
Significant Difference ◽  
Grade 3

Abstract Introduction Information on the long-term performance of biosynthetic meshes is scarce. This study analyses the performance of biosynthetic mesh (Phasix™) over 24 months. Methods A prospective, international European multi-center trial is described. Adult patients with a Ventral Hernia Working Group (VHWG) grade 3 incisional hernia larger than 10 cm2, scheduled for elective repair, were included. Biosynthetic mesh was placed in sublay position. Short-term outcomes included 3-month surgical site occurrences (SSO), and long-term outcomes comprised hernia recurrence, reoperation, and quality of life assessments until 24 months. Results Eighty-four patients were treated with biosynthetic mesh. Twenty-two patients (26.2%) developed 34 SSOs, of which 32 occurred within 3 months (primary endpoint). Eight patients (11.0%) developed a hernia recurrence. In 13 patients (15.5%), 14 reoperations took place, of which 6 were performed for hernia recurrence (42.9%), 3 for mesh infection (21.4%), and in 7 of which the mesh was explanted (50%). Compared to baseline, quality of life outcomes showed no significant difference after 24 months. Despite theoretical resorption, 10.7% of patients reported presence of mesh sensation in daily life 24 months after surgery. Conclusion After 2 years of follow-up, hernia repair with biosynthetic mesh shows manageable SSO rates and favorable recurrence rates in VHWG grade 3 patients. No statistically significant improvement in quality of life or reduction of pain was observed. Few patients report lasting presence of mesh sensation. Results of biosynthetic mesh after longer periods of follow-up on recurrences and remodeling will provide further valuable information to make clear recommendations. Trial registration Registered on clinicaltrials.gov (NCT02720042), March 25, 2016.

scholarly journals Engineering multifunctional bactericidal nanofibers for abdominal hernia repair

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Samson Afewerki ◽  
Nicole Bassous ◽  
Samarah Vargas Harb ◽  
Marcus Alexandre F. Corat ◽  
Sushila Maharjan ◽  
...  
Keyword(s):  
Hernia Repair ◽  
Biological Properties ◽  
Abdominal Hernia ◽  
Fabrication Technology ◽  
Tissue Adhesions ◽  
Blood Vessel Formation ◽  
Clinical Challenge ◽  
Engineering Strategy ◽  
Clinical Problems

AbstractThe engineering of multifunctional surgical bactericidal nanofibers with inherent suitable mechanical and biological properties, through facile and cheap fabrication technology, is a great challenge. Moreover, hernia, which is when organ is pushed through an opening in the muscle or adjacent tissue due to damage of tissue structure or function, is a dire clinical challenge that currently needs surgery for recovery. Nevertheless, post-surgical hernia complications, like infection, fibrosis, tissue adhesions, scaffold rejection, inflammation, and recurrence still remain important clinical problems. Herein, through an integrated electrospinning, plasma treatment and direct surface modification strategy, multifunctional bactericidal nanofibers were engineered showing optimal properties for hernia repair. The nanofibers displayed good bactericidal activity, low inflammatory response, good biodegradation, as well as optimal collagen-, stress fiber- and blood vessel formation and associated tissue ingrowth in vivo. The disclosed engineering strategy serves as a prominent platform for the design of other multifunctional materials for various biomedical challenges.

scholarly journals Antibacterial Biopolymer Gel Coating on Meshes Used for Abdominal Hernia Repair Promotes Effective Wound Repair in the Presence of Infection

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2371
Author(s):  
Selma Benito-Martínez ◽  
Bárbara Pérez-Köhler ◽  
Marta Rodríguez ◽  
Francisca García-Moreno ◽  
Verónica Gómez-Gil ◽  
...  
Keyword(s):  
Hernia Repair ◽  
Protein Expression ◽  
Mrna Expression ◽  
Abdominal Wall ◽  
Tissue Repair ◽  
Abdominal Hernia ◽  
Infection Model ◽  
Abdominal Wall Defects ◽  
Abdominal Hernia Repair ◽  
Gene And Protein Expression

Prosthetic mesh infection is a devastating complication of abdominal hernia repair which impairs natural healing in the implant area, leading to increased rates of patient morbidity, mortality, and prolonged hospitalization. This preclinical study was designed to assess the effects on abdominal wall tissue repair of coating meshes with a chlorhexidine or rifampicin-carboxymethylcellulose biopolymer gel in a Staphylococcus aureus (S. aureus) infection model. Partial abdominal wall defects were created in New Zealand white rabbits (n = 20). Four study groups were established according to whether the meshes were coated or not with each of the antibacterial gels. Three groups were inoculated with S. aureus and finally repaired with lightweight polypropylene mesh. Fourteen days after surgery, implanted meshes were recovered for analysis of the gene and protein expression of collagens, macrophage phenotypes, and mRNA expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs). Compared to uncoated meshes, those coated with either biopolymer gel showed higher collagen 1/3 messenger RNA and collagen I protein expression, relatively increased VEGF mRNA expression, a significantly reduced macrophage response, and lower relative amounts of MMPs mRNAs. Our findings suggest that following mesh implant these coatings may help improving abdominal wall tissue repair in the presence of infection.

scholarly journals Preclinical Bioassay of a Polypropylene Mesh for Hernia Repair Pretreated with Antibacterial Solutions of Chlorhexidine and Allicin: An In Vivo Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0142768 ◽  
Author(s):  
Bárbara Pérez-Köhler ◽  
Francisca García-Moreno ◽  
Thierry Brune ◽  
Gemma Pascual ◽  
Juan Manuel Bellón
Keyword(s):  
Hernia Repair ◽  
Polypropylene Mesh ◽  
In Vivo Study
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