scholarly journals Crossfit, musculação e corrida: vício, lesões e vulnerabilidade imunológica

2017 ◽  
Vol 86 (1) ◽  
Author(s):  
Thiago Guimarães ◽  
Marcos Carvalho ◽  
William Santos ◽  
Ercole Rubini ◽  
Wagner Coelho
Keyword(s):  
Physical Inactivity ◽  
Statistical Difference ◽  
Weight Training ◽  
Musculoskeletal Injuries ◽  
Exercise Dependence ◽  
Control Group ◽  
Weight Trainers ◽  
Total Dependence ◽  
And Control ◽  
One Way Anova

Introdução: A inatividade física figura como um dos principais fatores associados à mortalidade. Por outro lado, os possíveis prejuízos provocados pelo excesso de exercícios físicos não devem ser negligenciados.Objetivo: Avaliar e comparar o nível de dependência ao exercício entre diferentes modalidades, estimar a prevalência de lesões musculoesqueléticas e a vulnerabilidade imunológica em jovens assintomáticos.Métodos: Estudo observacional. Uma amostra com 219 pessoas foi dividida em cinco grupos: sedentários (e/ou insuficientemente ativos) (n=50), controle (moderadamente ativos) (n=31), praticantes de crossfit superativos (n=45), praticantes de musculação superativos (n=47) e corredores superativos (n=46). Além de uma anamnese para caracterizar a amostra e inferir o número de lesões musculoesqueléticas, gripes e infecções nos seis meses anteriores à coleta de dados, foi utilizada a Escala de Dependência de Exercício. Utilizou-se a ANOVA one way para analisar as diferenças estatísticas e para comparar os níveis de dependência total ao exercício, e a prevalência de lesões musculoesqueléticas, gripes e infecções.Resultados: O grupo musculação apresentou os maiores níveis de dependência ao exercício quando comparado com os grupos sedentários e controle (p<0,05). Quanto às lesões musculoesqueléticas, o grupo crossfit apresentou a maior prevalência, com diferença estatística em relação ao grupo controle. Gripes e infecções foram mais prevalentes nos grupos sedentários e musculação.Conclusão: Pessoas moderadamente ativas apresentaram menos lesões musculoesqueléticas e menor vulnerabilidade imunológica em relação a sedentários e superativos. A inatividade física e o vício em exercício parecem tornar o sistema imunológico mais vulnerável. Pessoas com hábitos extremos em relação à prática de atividades físicas (sedentários e adeptos superativos) podem ter a saúde comprometida.Crossfit, Weight Training and Running: Addiction, Injuries and Immunological VulnerabilityIntroduction: Physical inactivity is one of the main causes related to mortality. On the other hand, the possible damages caused by excessive exercise should not be neglected.Objective: To analyze the level of exercise dependence between different modalities, the prevalence of musculoskeletal injuries and immunological vulnerability in asymptomatic young people.Methods: This was an observational study. A sample of 219 people was divided into five groups: sedentary or insufficiently active (n=50), moderately active control (n=31), super active crossfitters (n=45), super active amateur weight trainers (n=47) and super active amateur runners (n=46). Additionally, an anamnesis to characterize the sample and to infer the number of musculoskeletal injuries, flus and infections in the six months prior to data collection, the Exercise Dependency Scale was used.  One way ANOVA was used to analyze the statistical differences and to compare the levels of total dependence to exercise, prevalence of musculoskeletal injuries, flu and infections.Results: The amateur weight trainers group presented higher levels of exercise dependence, with statistical difference in relation to the sedentary and control groups. Regarding the musculoskeletal lesions, the crossfit group presented the highest occurrence, with a statistical difference in relation to the control group. Flus and infections were more prevalent in sedentary and weight training groups.Conclusion: Moderately active people have fewer musculoskeletal injuries and less immunological vulnerability to sedentary and overactive ones. Physical inactivity and exercise addiction appear to make the immune system more vulnerable... People with extreme habits in relation to the practice of physical activities (sedentary and super active adepts) can have their health compromised.

scholarly journals Postoperative analgesia effects of sulfentanyl plus dexmedetomidine in patients received VATS

Pteridines ◽  
2020 ◽  
Vol 31 (1) ◽  
pp. 55-60
Author(s):  
Haoyu Jiang ◽  
Ying Zheng ◽  
Chang Liu ◽  
Ying Bao
Keyword(s):  
Statistical Difference ◽  
Control Group ◽  
Control Groups ◽  
Significant Statistical Difference ◽  
Post Surgery ◽  
Intravenous Analgesia ◽  
The Mean ◽  
Nsclc Patients ◽  
And Control ◽  
Time Point

AbstractBackground To evaluate sulfentanyl combined with dexmedetomidine hydrochloride on postoperative analgesia in patients who received video-assisted thoracic surgery (VATS) and its effects on serum norepinephrine (NE), dopamine (DA), 5-hydroxytryptamine (5-HT), and prostaglandin (PGE2).Material and Methods Ninety-nine non-small cell lung cancer (NSCLC) patients who received VATS were included in the study. All the patients received intravenous inhalation compound anesthesia. Of the 99 cases, 49 subjects (control group) received sulfentanyl for patient controlled intravenous analgesia (PICA) and other 50 cases (experiment group) received sulfentanyl combined with dexmedetomidine hydrochloride for PICA after operation of VATS. The analgesic effects of the two groups were evaluated according to Visual Analogue Scales (VAS) and the Bruggrmann Comfort Scale (BCS). The serum pain mediator of NE, DA, 5-HT, and PGE2 were examined and compared between the two groups in the first 24 h post-surgery.Results The VAS scores for the experiment group were significant lower than that of control group on the time points of 8, 16, and 24 h post-surgery (pall<0.05), and the BCS scores of the experiment group in the time points of 8, 16, and 24 h were significantly higher than that of controls (p<0.05). However, the VAS and BCS scores were not statistical differently in the time point of 1, 2, and 4 h post-surgery (pall>0.05). The mean sulfentanyl dosage was 63.01 ± 5.14 μg and 67.12 ± 6.91 μg for the experiment and control groups respectively with significant statistical difference (p<0.05). The mean analgesic pump pressing times were 4.30 ± 1.31 and 5.31 ± 1.46 for experiment and control groups respectively with significant statistical difference (p<0.05). The serum NE, DA, 5-HT, and PGE2 levels were significantly lower in the experimental group compared to that of control group in the time point of 12 h post-surgery (pall<0.05). The side effects of nausea, vomiting, delirium, rash, and hypotension atrial fibrillation were not statistically different between the two groups (pall>0.05).Conclusion Patient controlled intravenous analgesia of sulfentanyl combined with dexmedetomidine hydrochloride was effective in reducing the VAS score and serum pain mediators in NSCLC patients who received VAST.

scholarly journals Biomonitoring Data for Assessing Aflatoxins and Ochratoxin A Exposure by Italian Feedstuffs Workers

Toxins ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 351 ◽  
Author(s):  
Barbara De Santis ◽  
Francesca Debegnach ◽  
Elisa Sonego ◽  
Gianmarco Mazzilli ◽  
Francesca Buiarelli ◽  
...  
Keyword(s):  
Ochratoxin A ◽  
Statistical Difference ◽  
High Resolution Mass Spectrometry ◽  
Control Group ◽  
Control Groups ◽  
Serum Samples ◽  
Limit Of Quantification ◽  
Liquid Liquid Extraction ◽  
And Control

Mycotoxins exposure by inhalation and/or dermal contact is possible in different branches of industry especially where heavily dusty settings are present and the handling of dusty commodities is performed. This study aims to explore the validity of the biomonitoring as a tool to investigate the intake of mycotoxins in a population of workers operating in an Italian feed plant. Serum samples were collected for the determination of aflatoxins B1 (AFB1), AFB1-Lysine adduct and ochratoxin A (OTA). A method based on liquid–liquid extraction coupled with high resolution mass spectrometry determination was developed and fully validated. For AFB1, a high number of non-detected samples (90%) was found and no statistical difference was observed comparing workers and control group. None of the analyzed samples showed the presence of AFB1-Lysine adduct. For OTA, the 100% of the analyzed samples was positive with a 33% of the samples showing a concentration higher than the limit of quantification (LOQ), but no statistical difference was highlighted between the average levels of exposed and control groups. In conclusion, the presence of AFB1 and OTA in serum cannot be attributable to occupational exposure.

scholarly journals Cryotherapy Reduced Postoperative Pain in Gynecologic Surgery: A Randomized Controlled Trial

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Apisada Chumkam ◽  
Densak Pongrojpaw ◽  
Athita Chanthasenanont ◽  
Junya Pattaraarchachai ◽  
Kornkarn Bhamarapravatana ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Statistical Difference ◽  
Controlled Trial ◽  
Exploratory Laparotomy ◽  
Gynecologic Surgery ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
Vas Score ◽  
And Control

Objective. To examine the effectiveness of cryotherapy for reducing postoperative pain in patients who underwent exploratory laparotomy for gynecologic surgery. Materials and Methods. Patients who had indication for an exploratory laparotomy gynecologic procedure were selected by attending physicians to undergo abdominal surgery via low transverse skin incision. The participants were randomized into study and control groups with simple random sampling methods. Cold packs were applied at two hours after operation for 6 hours. The visual analog scale (VAS) score was recorded at two, 6, and 12 hours after operation. Result. One hundred cases were recruited and then divided into study and control groups equally. The mean age of both groups was 43 years. There was no difference in demographics data of both groups. Half of the participants in both groups underwent hysterectomies. At two hours after surgery, both groups had similar VAS scores. The study group had a lower VAS score at 6 and 12 hours after surgery than the control group with statistical difference. Morphine consumption within 24 hours after surgery in both the study and control groups was 2.8±3.4 and 3.0±4.4 mg, respectively, with no statistical difference. However the registration time of the first morphine requirement in the study group was statistically more prolonged than that of the control group. The lengths of hospital stay in both groups were similar. There was no complication reported in this study. Conclusion. Cryotherapy can reduce postoperative pain. In this presented study the patients who underwent gynecologic surgery had improved pain relief and prolonged time for the first dose of the analgesic drug.

Interferon Gamma +874A/T Polymorphism in Children with Idiopathic Thrombocytopenic Purpura

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 4539-4539
Author(s):  
Fatih Demircioglu ◽  
Hale Ören ◽  
Sefa Kizildag ◽  
Sebnem Yilmaz ◽  
Berna Atabay ◽  
...  
Keyword(s):  
Allele Frequency ◽  
Interferon Gamma ◽  
Gene Polymorphisms ◽  
Statistical Difference ◽  
Control Group ◽  
Blood Samples ◽  
Chronic Itp ◽  
Significant Difference ◽  
Acute Itp ◽  
And Control

Abstract A recent study showed that expression of Toll-like receptor and interferon-gamma associated genes is significantly increased in patients with chronic ITP. Interferon-gamma is an important protein which takes place in immunoregulation. +874A/T polymorphism in the first introne of interferon gamma gene is found to be associated with the development and clinical phenotype of some autoimmune diseases such as diabetes mellitus, thyroiditis, multiple sclerosis, and SLE. The aim of our study was to investigate whether interferon gamma +874A/T polymorphism is a risk factor for the development of ITP and whether it affects the clinical course and response to the treatment. Thirty five children with acute ITP and 40 children with chronic ITP who were followed for at least 6 months were included. Control group consisted 90 healthy children. Two millilitres of blood sample was taken into sterile tubes containing 0.1% EDTA from each child and all blood samples were stored at −20 until analysis. DNA was isolated from blood samples and interferon gamma +874A/T polymorphism was studied with real-time PCR and LightCycler TM. Twenty one patients had AA, 35 patients had AT, and 19 patients had TT genotype. In the control group, 47 children had AA, 36 children had AT, and 7 children had TT genotype. There was a statistical difference between ITP and control group regarding the genotype (p=0.001). The frequency of A and T alleles in ITP group was 52% and 48%, respectively. The frequency of A and T alleles in control group was 72.7% and 27.8%, respectively. The frequency of allele distribution was statistically different between the ITP and control groups (p&lt;0.0001). There was a statistical significant difference between acute ITP and control group regarding the frequency of AA, AT, and TT gene polymorphisms and allele frequency (p=0.002, p=0.002). Similarly, there was a statistical significant difference between chronic ITP and control group regarding the frequency of AA, AT, and TT gene polymorphisms and allele frequency (p=0.008, p=0.002). The frequency of AA, AT, and TT gene polymorphisms and allele frequency showed no statistical difference between acute and chronic ITP groups (p=0.285, p=0.896). There was no correlation between interferon gamma +874A/T polymorphism and severity of bleeding (mild, moderate and severe) (p=0.09). There was no correlation between interferon gamma +874A/T polymorphism and response to long term treatment in patients with chronic ITP (p=0.568). In conclusion, there was a significant difference between patients with ITP and children in control group regarding interferon gamma +874A/T polymorphism and in the light of recent data involving other autoimmune disorders, we think that interferon gamma +874A/T polymorphism may be a risk factor for ITP.

Effect of Aspirin Pre- and Postburn on Survival of Experimental Intermediate Burns in Rats

2011 ◽  
Vol 15 (2) ◽  
pp. 111-114
Author(s):  
Eran Hadad ◽  
Melvyn Westreich ◽  
Tal Friedman ◽  
Avshalom Shalom
Keyword(s):  
Health Care ◽  
Cell Death ◽  
Statistical Difference ◽  
Burn Injury ◽  
Control Group ◽  
Control Groups ◽  
Burn Wound ◽  
Major Health ◽  
Flap Survival ◽  
And Control

Background:Burns are a major health care problem. Early treatment increases survival of intermediate burn zones, thus decreasing morbidity, mortality, surgery, and hospitalization. Previously, aspirin was shown to improve burn perfusion and increase failing flap survival.Objective:Owing to similarities between failing flaps and intermediate burn zones, we conducted this study to evaluate the effect of aspirin on intermediate burn zone survival.Methods:An intermediate burn was created in 30 rats randomly divided into three experimental groups: pre- and postburn aspirin groups and a control group. Final burn survival was evaluated on day 7.Results:No statistical difference was observed between the test and control groups. Both aspirin regimens failed to improve intermediate burn survival.Conclusion:Presumably, administration of aspirin could not prevent the noxious tissue events of burn injury that cause cell death. Possibly, different dosages or modes of administering aspirin could have a beneficial effect on burn wound survival.

scholarly journals Measurement of serum and peritoneal fluid LH concentrations as a diagnostic tool for human endometriosis

Reproduction ◽  
2001 ◽  
pp. 761-769 ◽  
Author(s):  
JC Illera ◽  
G Silvan ◽  
MJ Illera ◽  
CJ Munro ◽  
BA Lessey ◽  
...  
Keyword(s):  
Predictive Value ◽  
Peritoneal Fluid ◽  
Polyclonal Antiserum ◽  
Control Group ◽  
Standard Curve ◽  
Serum Lh ◽  
Assay Time ◽  
Cycle Dependent ◽  
And Control ◽  
One Way Anova

A rapid, sensitive enzymeimmunoassay for the measurement of LH concentrations in serum and peritoneal fluid samples of healthy women and women with endometriosis is reported. The ligand (LH) was captured by a readily available, widely used and well-characterized monoclonal antibody (mAb, 518B7) generated against the beta subunit of bovine LH. This mAb, although specific for LH, shows very little species specificity and detects LH by radioimmunoassay in humans. A polyclonal antiserum raised in rabbits against hCG was conjugated to horseradish peroxidase and was used as the second antibody signal. This anti-hCG antiserum crossreacts with LH. The enzymeimmunoassay uses the standard human LH (hLH) preparations (NIADDK-hLH-I-3, AFP-827OB) and results are based on the relative concentrations of LH in serum and peritoneal fluid. Total assay time was < 3 h. The range of the standard curve was 0.002-0.500 ng LH per well and the lowest concentration of hLH that could be distinguished from zero concentration was 0.15 +/- 0.02 ng ml(-1) serum and 0.058 +/- 0.021 ng ml(-1) peritoneal fluid. Clinical diagnostic parameters for the LH enzymeimmunoassay showed a sensitivity of 85.71%, specificity 92.50%, efficiency 88.54%, positive predictive value 94.11% and negative predictive value 82.22%. The study was retrospective. Serum LH concentrations of women with endometriosis were 13.67 +/- 7.21 ng ml(-1), whereas serum LH concentrations of women in the control group were 4.52 +/- 2.03 ng ml(-1). One-way ANOVA showed significant differences (P < 0.001) between women with endometriosis and control groups. Women in the control group had peritoneal fluid LH values of 5.65 +/- 2.43 ng ml(-1), whereas peritoneal fluid LH values of 64.06 +/- 16.44 ng ml(-1) were obtained in women with endometriosis (P < 0.001). A cycle-dependent pattern of serum and peritoneal fluid LH concentration was observed in women in the control group, which was not observed in the peritoneal fluid of the group with endometriosis. The application of this assay to serum or peritoneal fluid samples provides the attractive possibility that it could be included in the panel of markers used for diagnosis of endometriosis.

scholarly journals The Effect of Grammar Teaching Methods on Students’ Writing Skill

IJOHMN ◽  
2021 ◽  
Vol 7 (4) ◽  
Author(s):  
Fadiel Mohammed Musa
Keyword(s):  
Teaching Methods ◽  
English Learners ◽  
Statistical Difference ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Grammar Teaching ◽  
Writing Skill ◽  
And Control ◽  
Teaching Grammar

This study investigates the effect of grammar teaching methods on students’ writing skill in secondary level. The study was based on action research, carried out in the academic year 2017 in one of Sudanese secondary schools. The participants were in second year. They studied English for the same number of years (6 years).The study followed two different methods of grammar teaching: 1) grammar in 'context' and 2) in 'isolation' to assess which method is more beneficial for English learners to write grammatical error-free composition. Students were divided into two groups: control and experimental groups.For the purpose of high measurement, participants in the two groups sat for apre English test on writing. The results showed that P-value of T-test (0.567) was greater than significant level (0.05) which means there was no statistical difference between experimental and control groups in the pre-test. Then the experiment was run; teaching the two groups using different methods.The control group was taught grammarin isolation method; where experimental group was taught grammar in context.Instructions lasted for two months and the two groups had the same writing test. The results indicated that P-value of T-test (0.000) was less than significant level (0.05) which means there was statistical difference between experimental and control in post-test. Finding showed that: teaching grammar ‘in context’ helps students to produce better writing than teaching grammar ‘in isolation’.

scholarly journals Effect of Aquarobic and Weight Training on Cortisol Levels in Obese Women

2016 ◽  
Vol 12 (1) ◽  
Author(s):  
Siti Baitul Mukarromah ◽  
Hardhono Susanto ◽  
Tandiyo Rahayu
Keyword(s):  
Weight Training ◽  
Physical Stress ◽  
Control Group ◽  
Obese Women ◽  
Control Group Design ◽  
Handling Stress ◽  
Before And After ◽  
Cortisol Levels ◽  
The Difference ◽  
And Control

Exercise is physical stress which potentially causes disruption of homeostasis, especially in sports that is excessively done. Weight Training (LB) and Aquarobic Exercise (LA) can be modulators of handling stress. This research aims at investigating the effect of the difference between LB and LA to physical stress in obese women. The study was conducted in 2014. The method used in this study was randomized experimental pretest-posttest control group design in 36 obese women, aged 45-50 years who were divided into 3 groups, group LB 50% RM, 3 sets, 12 repetition, treatment two times a day for 8 weeks (n = 12), LA 75% HRmax, treatment 2 days for 8 weeks (n = 12) and control group (n = 12). Body Mass Index (BMI) and cortisol levels were measured before and after the treatment. Hypothesis testing was conducted using test (One-Way ANOVA and Kruskal-Wallis) and the mean difference test (Tukey HSD and Mann Whitneys). The results of BMI is increased in the WT group and is decreased in LA group as compared to control group (p <0.05). The decrease of cortisol level is higher than in LA and LB group and controls (p <0.05). LB and LA affect the physical stress that is characterized by the increase in cortisol levels in obese women. Conclusion: LB is more dominant than LA in increasing physical stress.

scholarly journals Effects of Hydroxychloroquine on Proteinuria in IgA Nephropathy: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Jialing Zhang ◽  
Xiangxue Lu ◽  
Jianan Feng ◽  
Han Li ◽  
Shixiang Wang
Keyword(s):  
Systematic Review ◽  
Iga Nephropathy ◽  
Therapeutic Effect ◽  
Statistical Difference ◽  
Meta Analysis ◽  
Immunosuppressive Agents ◽  
Control Group ◽  
Percentage Reduction ◽  
And Control

Introduction. The present meta-analysis was to explore the efficacy of hydroxychloroquine (HCQ) in IgA nephropathy patients in terms of proteinuria. Method. We systematically searched PubMed and Embase for studies that compared HCQ and other treatments to reduce proteinuria in patients with IgA nephropathy up to June 2021. Mean ± SD of percentage change and level of proteinuria was calculated. Results. A total of 5 studies with 587 participants were included. IgA nephropathy patients who received HCQ were at a lower level of mean proteinuria at 6 months. However, there was no statistical difference between HCQ and control group considering percentage reduction in proteinuria. The long-term therapeutic effect of HCQ might be inferior to HCQ and renin-angiotensin-aldosterone system inhibition. Conclusion. HCQ might play a role in the reduction of proteinuria in IgA nephropathy patients. The addition of HCQ to other immunosuppressive agents should be clarified further.

scholarly journals Efecto del entrenamiento en ábaco mental sobre la flexibilidad cognitiva: un estudio exploratorio

2020 ◽  
Vol 18 (3) ◽  
pp. 316-323
Author(s):  
Daniela Giorgetti ◽  
Emilio López-Navarro ◽  
Enric Munar
Keyword(s):  
Cognitive Flexibility ◽  
Mental Arithmetic ◽  
Control Group ◽  
Promising Tool ◽  
Trail Making ◽  
And Control ◽  
Arithmetic Instruction ◽  
Math Problems ◽  
Academic Year ◽  
One Way Anova

Mental Abacus (MA) training teaches students to solve math problems by visualizing a physical abacus structure to perform arithmetic operations. Research shows that MA practice relates with enhanced working memory in children, but other cognitive processes that could mediate the benefits registered remain unknown. The aim of the study was to analyze the effect of MA training in a cognitive flexibility task in twelve-year-old children, and compare it with a control group. 121 children from the sixth course of primary education were recruited. 54 students received MA training added during the academic year, while the control group received normative arithmetic instruction. MA training was provided by UCMAS Mental Arithmetic Spain S.L. To assess cognitive flexibility, we used the Trail Making Test (TMT). Data analysis entailed parametric assumptions check and a one-way ANOVA between MA and control group. There were no differences between groups in age. There were statistical differences in TMT-A (Z=-5,78, p<,001, d=,67) and TMT-B scores (Z=-2,24, p=,021, d=,08). Our data suggest that MA enhances cognitive flexibility in children. MA is a promising tool teaching math which benefits go beyond arithmetic calculation.

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