scholarly journals Thyroid Profile in Infertile Women

2018 ◽  
Vol 1 (01) ◽  
pp. 5-10
Author(s):  
Rojina Manandhar ◽  
Bekha Laxmi Manandhar ◽  
Jyoti Sharma
Keyword(s):  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Subclinical Hyperthyroidism ◽  
Secondary Infertility ◽  
Cross Sectional ◽  
Infertile Women ◽  
Thyroid Profile

Introduction: Infertility is defined as inability to conceive after one year of regular unprotected intercourse. Thyroid disorders can lead to infertility arising from different pathophysiological mechanisms. The aim of this study is to determine the prevalence and type of thyroid disorder in infertile women and to compare the prevalence of thyroid disorder in primary and secondary infertility. Methods: A hospital-based descriptive cross-sectional study conducted in the Department of Obstetrics and Gynecology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal from 1st Baishak 2068 to 30th Chaitra 2068 (14th April 2011 to 12th April 2012). Results: Among 156 infertile women enrolled and analyzed in the present study, thyroid disorder was found in 12 women giving the prevalence of thyroid disorder in infertile women as 7.7%. Hypothyroidism was more common comprising 6.4% of all infertile women, out of which subclinical hypothyroidism was 3.8% and clinical hypothyroidism was 2.6%. Hyperthyroidism was seen in 1.3% of all infertile women of which subclinical hyperthyroidism was 0.64% and clinical hyperthyroidism was 0.64%. Prevalence of thyroid disorder in primary infertility was 9.8% and in secondary infertility it was 3.7%. Among the 12 infertile women with thyroid disorder, four infertile women (33%) conceived. Three cases of hypothyroidism conceived after treatment and one case of subclinical hyperthyroidism conceived without any treatment. Conclusions: This study shows that thyroid dysfunction shows a significant role in infertility. Proper management of the thyroid dysfunction can result regain of fertility. Therefore, routine screening is required to all cases of infertility for possible thyroid disorders.

scholarly journals Thyroid Disorders and Prolactin Hormone and Their Association with Obesity in Infertile Women in a Tertiary Hospital of Nepal

2020 ◽  
Vol 42 (3) ◽  
pp. 7-11
Author(s):  
Suvana Maskey ◽  
Hima Rijal
Keyword(s):  
Thyroid Function Test ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
University Teaching ◽  
Serum Prolactin ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
Infertile Women

Introduction Thyroid dysfunction has profound effects on menstrual function and female fertility. Hypothyroidism is often associated with increased prolactin level which again worsens the problem. This study was done to evaluate the prevalence of thyroid disorders in infertile women attending infertility outpatient department (OPD) in Tribhuvan University Teaching Hospital (TUTH) and to determine the association of hypothyroidism and hyperprolactenemia with obesity which is not well studied in our population. MethodsA hospital-based cross-sectional study was conducted in infertility OPD of TUTH reviewing women’s records who underwent infertility workup and relevant history, clinical finding and results of investigations including thyroid function test (TFT) and serum prolactin (PRL) level were documented. Descriptive and inferential statistical analyses were used to identify the prevalence and associations of predictors and outcome variables. ResultsOut of 213 participants, the majority of the participants were obese (90; 42.3%) with mean (±SD) body mass index (BMI) being 24.8 ± 4.5 kg/m2. The prevalence of thyroid disorder was 18.4% including hypothyroidism 13.6% and hyperthyroidism 4.8%. There was no significant association of BMI and hyperprolactinemia with thyroid disorder as well as of BMI with hyperprolactinemia however the thyroid stimulating hormone (TSH) had significant positive correlation with prolactin (r=0.23, p<0.001). ConclusionThyroid disorders and hyperprolactinemia are commonly observed in infertile women, so they should be routinely screened during initial evaluation of infertility. As majority of the study population were obese, despite no significant association of BMI with thyroid disorder and hyperprolactinemia, the effect of weight gain on infertility cannot be overlooked.

DYSLIPIDEMIA IN THYROID DISORDERS

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Kashish Narula ◽  
Narendra Kumar Dara ◽  
Shyam Lal Meena
Keyword(s):  
Lipid Metabolism ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Control Group ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
Carbohydrate And Lipid Metabolism ◽  
History Of ◽  
Thyroid Profile ◽  
Basal Energy Expenditure

Background: Thyroid hormones influence nearly all major metabolic pathways. Their most obvious and well-known action is the increase in basal energy expenditure obtained by acting on protein, carbohydrate and lipid metabolism. The lipid metabolism is more influenced by the thyroid hormone. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results: The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: Dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Thyroid profile, Total cholesterol, Triglycerides and LDL

scholarly journals DYSLIPIDEMIA IN THYROID DISORDERS

2019 ◽  
Vol 3 (12) ◽  
Author(s):  
Daulat Meena ◽  
Ramavatar Bairwa
Keyword(s):  
Thyroid Hormones ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Metabolic Effects ◽  
Control Group ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
History Of ◽  
Thyroid Profile ◽  
Lipid Abnormalities

Background: Thyroid hormones have profound metabolic effects, the most striking action being an increase in energy expenditure. Thyroid hormones play an important role in regulating lipid metabolism; and thyroid dysfunctions can result in lipid abnormalities which increase the risk of endothelial dysfunction, hypertension and cardiovascular disease. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results- The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: We conclude that, dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Total cholesterol, Triglycerides and LDL.

scholarly journals Prevalence and Characteristics of Thyroid Abnormalities and Its Association with Anemia in ASIR Region of Saudi Arabia: A Cross-Sectional Study

2021 ◽  
Vol 11 (3) ◽  
pp. 494-504
Author(s):  
Saif Aboud M. Alqahtani
Keyword(s):  
Saudi Arabia ◽  
Thyroid Dysfunction ◽  
Research Work ◽  
Cross Sectional Study ◽  
Primary Hypothyroidism ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
Hematological Disorders ◽  
Asir Region

The thyroid gland plays a significant role in the metabolism and proliferation of blood cells; hematological disorders are frequently observed in patients with thyroid disorders, and the most frequent problem is anemia. The main objective of this research work is to evaluate the prevalence and types of thyroid dysfunction and their association with anemia in different gender stratified by age in the Asir region of Saudi Arabia. Four years of data from July 2016 to July 2020 for 9992 study subjects were collected. Statistical analysis was performed based on thyroid disorder and anemia stratified by gender and age subgroup. The mean age of the study subject was 43.4 ± 15.8 years, and females constituted 61.7% of cases. Thyroid dysfunction was observed in 49.76% (4973), and subclinical hypothyroidism was the most prevalent type (3922/9992), followed by primary hypothyroidism (530/9992). Females have a significantly higher overall prevalence of thyroid dysfunction than males (p < 0.05). Anemia was detected in 1344 females and 465 males with a thyroid disorder, and also, the prevalence was significantly higher (p < 0.05), compared to the normal thyroid group. Thyroid disorders are a common problem in our population, more prevalent in females than males, with the peak age of above 30 years, and are associated with an increased prevalence of anemia.

scholarly journals DYSLIPIDEMIA IN THYROID DISORDERS

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Ashok Kumar ◽  
Saurabh Gupta ◽  
Vaishali Nimbalkar
Keyword(s):  
Thyroid Hormones ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Metabolic Effects ◽  
Control Group ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
History Of ◽  
Thyroid Profile ◽  
Lipid Abnormalities

Background: Thyroid hormones have profound metabolic effects, the most striking action being an increase in energy expenditure. Thyroid hormones play an important role in regulating lipid metabolism; and thyroid dysfunctions can result in lipid abnormalities which increase the risk of endothelial dysfunction, hypertension and cardiovascular disease. Methods-A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results- The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: We conclude that, dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Total cholesterol, Triglycerides and LDL.

scholarly journals Prevalence of thyroid disorders among infertile women with menstrual irregularities

2018 ◽  
Vol 6 (1) ◽  
pp. 22-25
Author(s):  
Nazlima Nargis ◽  
Abu Kholdun Al Mahmood ◽  
Iqbal Karim
Keyword(s):  
Cross Sectional Study ◽  
Thyroid Disorders ◽  
Secondary Infertility ◽  
Cross Sectional ◽  
Detailed History ◽  
Infertile Women ◽  
Ovulatory Dysfunction ◽  
Menstrual Irregularities ◽  
Menstrual History ◽  
History Of

Background: The infertility problem is more common phenomenon among the women now a days and has increased over past 30 years. The present study was carried out to see the prevalence of thyroid disorders among infertile women with menstrual irregularities.Methods: It was a cross sectional study conducted at the Department of Obstetrics and Gynecology, Ibn Sina Medical College, Dhaka from January to December 2016. After taking informed consent, total 160 infertile women and 100 normal fertile women volunteers were selected on OPD basis between age group of 18-45 years. Out of 160 infertile women, 100 were of primary infertility and 60 of secondary infertility. Participants were selected on the basis of detailed history, clinical examination and laboratory investigations. Detailed history of participants including age, menstrual history, obstetric history, history of any medications were taken.Results: There was a higher prevalence of hypothyroidism in the infertile women as compared to the fertile one in the study group, particularly in secondary infertility. Oligomenorrhoea was most common in infertile women. Hypothyroidism is commonly associated with ovulatory failure. Hence, assessment of serum TSH is mandatory in the work up of all infertile women, especially those presenting with menstrual irregularities. So the basic approach should be to identify those hypothyroid individuals who have greatest risk for the development of infertility.Conclusion: Long standing hypothyroidism may develop ovulatory dysfunction. So identifying and treating hypothyroidism at an earlier stage before the appearance of ovulatory dysfunction can have potentially great preventive value.Bangladesh Crit Care J March 2018; 6(1): 22-25

scholarly journals Prevalence of Thyroid Dysfunction in Irritable Bowel Syndrome

2018 ◽  
Vol 4 (2) ◽  
pp. 1-5
Author(s):  
Mohan Khadka ◽  
Brindeshwori Kafle ◽  
Sashi Sharma ◽  
Prem Krishna Khadga
Keyword(s):  
Irritable Bowel Syndrome ◽  
Thyroid Dysfunction ◽  
Public Health Problem ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
Rome Iii ◽  
Irritable Bowel

INTRODUCTION: Irritable bowel syndrome (IBS) is a common public health problem. The condition is characterized by a scarcity of biological markers; thus, diagnostic definitions and classifications have relied to a large extent on symptoms, gastrointestinal manifestations of patients. While thyroid disorder should be considered in the differential diagnosis of patients with IBS symptoms, it is not clear if thyroid disturbances amongst patients with IBS are high enough to warrant routine screening. This study was done to see the prevalence of thyroid dysfunction in IBS patients and hence its significance.  MATERIALS AND METHODS: A cross-sectional study conducted at the Gastroenterology OPD of the Tribhuvan University Teaching Hospital, Kathmandu, Nepal between March 2015 and April 2016. All the consecutive patients presumed to be Irritable bowel syndrome by Rome III criteria were enrolled in the study. Thyroid Function Test (TFT) was performed in all patients in addition to routine investigations for the study group that include measurement of thyroid hormones (T3 and T4) together with thyrotropin stimulating hormone (TSH).  RESULTS: Thyroid dysfunction particularly subclinical hypothyroidism was substantially found among patients with IBS. CONCLUSION: Routine TFTs in patients with presumed IBS seems reasonable. Journal of Universal College of Medical Sciences (2016) Vol.04 No.02 Issue 14, page: 1-5   

Prevalence and distribution of causes of infertility according to women’s age – a cross-sectional study in a tertiary healthcare hospital setup

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Keerthana Dhandapani ◽  
Bhagyalakshmi Kodavanji ◽  
Vinodini Nithyananda Madom Anantharaya ◽  
Nayanatara Arun Kumar
Keyword(s):  
Tertiary Care ◽  
Developed Countries ◽  
Cross Sectional Study ◽  
Female Infertility ◽  
Secondary Infertility ◽  
Cross Sectional ◽  
Female Population ◽  
Infertile Women ◽  
Tertiary Healthcare ◽  
The Individual

Abstract Objectives Infertility has disastrous consequences, particularly for women. Causes of infertility in developed countries have been investigated but there is a significant lack of data among Indian female population. The aim of the present study was to analyze the causes and the proportion of the individual factors contributing to infertility, considering the age factor. Methods The data of 204 infertile women (18–45 years) were collected from the files in tertiary care hospitals. Causes and age of infertile women were grouped. The prevalence of each cause was evaluated. Data analysis was done using SPSS (Statistical Package for Social Sciences) version 17.0. Results Polycystic ovarian syndrome (PCOS) was the most common (14.71%) cause of female infertility. Ovulatory dysfunctions (25.55%) were the foremost cause in primary infertility, whereas in secondary infertility, uterine factors (26.86%) were most common. The incidence of primary and secondary infertility was more evident in patients who were more than 30 years of age. Conclusions Causes of infertility vary according to the age. The causes of female infertility were unexplained infertility, ovulatory disorders and uterine factors most commonly affecting women at ≤30 years.

scholarly journals Thyroid disorders in women with dysfunctional uterine bleeding

2016 ◽  
Vol 6 (12) ◽  
pp. 1018-1020
Author(s):  
S Subedi ◽  
B Banerjee ◽  
C Manisha
Keyword(s):  
Reproductive Function ◽  
Hormonal Treatment ◽  
Abnormal Uterine Bleeding ◽  
Cross Sectional Study ◽  
Uterine Bleeding ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Dysfunctional Uterine Bleeding ◽  
Cross Sectional ◽  
Menstrual Pattern

Background: Thyroid hormones play a key role in the menstrual and reproductive function of women .It is recognized universally that menstrual disturbances may accompany clinical alteration in thyroid function and every clinician has encountered altered menstrual pattern among women suffering from thyroid disorders. The aim of this study was to find the incidence of thyroid disorders in Dysfunctional uterine bleeding and its correlation with menstrual patterns.Materials and Methods: A hospital based cross-sectional study including 75 cases with dysfunctional uterine bleeding attending the OPD of Nobel Medical College, where incidence of thyroid disorder was evaluated along with its correlation with menstrual patterns and histopathology.Results: The incidence of Gynecological OPD attendance due to abnormal uterine bleeding was 3%.and the incidence of thyroid dysfunction was 10.6% with hypothyroidism being the commonest. (9.3%). The commonest menstrual pattern found was menorrhagia/polymenorrhoea in 8 percent.Conclusion: Prevalence of hypothyroidism was more common in DUB. Thus every woman with menstrual irregularities should undergo thyroid assessment and this will ultimately avoid unnecessary intervention like misuse of hormonal treatment and hysterectomy.

scholarly journals Prevalence of thyroid dysfunction in women with abnormal uterine bleeding in reproductive age

2020 ◽  
Vol 9 (7) ◽  
pp. 2792
Author(s):  
Hema K. R. ◽  
Girish B. L. ◽  
Dhananjaya B. S. ◽  
Riyaj Ahmad Kalaburgi
Keyword(s):  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Cross Sectional Study ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
Thyroid Profile ◽  
Definitive Management

Background: Abnormal uterine bleeding (AUB) is one of the commonest presentations encountered in gynecological outpatient department. Menstruation is also regulated by many mechanisms, including thyroid hormone. So, for definitive management of AUB, it becomes imperative to assess thyroid status in those with abnormal uterine bleeding.Methods: Cross sectional study was conducted on all woman attending to OPD at Sri Siddhartha Medical College, Tumukuru, with complaints of abnormal uterine bleeding (AUB). Thyroid test was done for those who were eligible under inclusion criteria. Incidence of thyroid disorders among AUB and type of abnormal menstrual pattern associated with specific type of thyroid dysfunction were noted in this study.Results: Total of 522 presented with AUB. AUB was most common among woman age >40 years at 49.23% (257 of total 522 cases). AUB was more common in Multipara at 61.49% (321 of 522 cases). Menorrhagia was commonest pattern in AUB accounting for 51.34% (268 of 522cases). Thyroid dysfunction was present in 12.27% (64 of 522) of cases with AUB. Among them hypothyroid was most common accounting for 8.81% (46 of 522 cases). Hyperthyroidism was present in 3.44% (18 of 522 cases). Menorrhagia was most common pattern in Hypothyroidism at 65.21% (30 of 46 cases, followed by polymenorrhea at 17.39% (8 of 46 cases). Oligomenorrhea was most common in hyperthyroid group at 55.54% (10 of 18 cases) closely followed by hypomenorrhea at 44.44% (8 of 18 cases).Conclusions: Abnormal uterine bleeding (AUB) is one of the commonest gynecological complaint at gynecological OPD.  Thyroid dysfunction is noted consistently in cases of AUB. So, evaluation of thyroid profile should be part of evaluation of AUB, especially during perimenopause.

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