scholarly journals THE EFFICIENCY OF LEVOCETIRIZINE IN TREATMENT OF ALLERGIC SKIN DISEASES

2012 ◽  
Vol 9 (5) ◽  
pp. 69-75
Author(s):  
O G Elisyutina ◽  
E S Fedenko ◽  
T G Fedoskova ◽  
L V Luss
Keyword(s):  
Atopic Dermatitis ◽  
Chronic Urticaria ◽  
Skin Diseases ◽  
Clinical Efficiency ◽  
Allergic Skin

In the article the results of supervision over the patients with chronic urticaria (n=32) and atopic dermatitis (n=30), at the age from 2 till 55 years old treated with H^blocker levocetirizine, are presented. High clinical efficiency and safety of levocetirizine treatment of allergic skin diseases were confirmed.

Calcineurin Inhibitors: A Novel Approach to Canine Atopic Dermatitis

2005 ◽  
Vol 41 (2) ◽  
pp. 92-97 ◽  
Author(s):  
Rosanna Marsella
Keyword(s):  
Atopic Dermatitis ◽  
Adverse Effects ◽  
Mechanism Of Action ◽  
Broad Spectrum ◽  
Skin Diseases ◽  
Calcineurin Inhibitors ◽  
Relevant Information ◽  
Novel Approach ◽  
Allergic Skin ◽  
Traditional Therapies

The introduction of calcineurin inhibitors represents a major addition to the armamentarium of drugs available to veterinary clinicians for the management of allergic skin diseases. Both cyclosporine and tacrolimus have been proven to be well tolerated and effective for the treatment of atopic dermatitis in dogs. Although broad spectrum in their mechanism of action, they lack the major adverse effects of glucocorticoids and provide an appealing alternative to traditional therapies. The purposes of this article are to review clinically relevant information regarding these agents and to provide tips for maximizing the benefit obtained from these therapies.

scholarly journals CLINICAL AND DIAGNOSTIC VALUE OF DETERMINATION OF NEOPTERIN IN ATOPIC DERMATITIS IN CHILDREN

2018 ◽  
Vol 25 (3) ◽  
pp. 24-27
Author(s):  
M. M. BEN ◽  
E. YU. YANCHEVSKAYA ◽  
O. A. MESNYANKINA
Keyword(s):  
Atopic Dermatitis ◽  
Skin Diseases ◽  
Secondary Infection ◽  
Clinical Manifestations ◽  
Diagnostic Value ◽  
Laboratory Method ◽  
Control Group ◽  
Allergic Skin ◽  
Monitoring And Forecasting

Aim. To improve the diagnosis of allergic skin diseases in childrenMaterials and methods. 135 children aged from 2 to 6 with atopic dermatitis were examined during exacerbation. They were on inpatient treatment in the skin and venereologic department of the Regional skin and venereologic dispensary and the Department of Allergology of the Regional children's clinical hospital. At the same time, 103 people (the main group) had uncomplicated course of the disease, 32 patients had complications of atopic dermatitis in the form of secondary infection. The control group consisted of 29 children aged 2 to 6. Neopterin in serum was determined by enzyme-linked immunosorbent analysis using test kits "Neopterin ELISA" (Germany). Statistical reliability of the obtained data was evaluated using The Student's test.Results. Atopic dermatitis in children, regardless of clinical manifestations, is accompanied by an increase in the content of neopterin in serum. The nature of the increase in the level of neopterin is determined by the duration of the disease, while its highest values are characteristic of the prolonged course of the process (over 4 years).Conclusion. The determination of neopterin in children with atopic dermatitis is a promising laboratory method for assessing the severity of dermatosis, monitoring and forecasting the further course of the process, as well as evaluating the effectiveness of therapeutic measures.

scholarly journals ACUPUNCTURE IN TREATMENT OF РАTIENTS WITH CRONIC DERMATOSES

2020 ◽  
Vol 74 (2) ◽  
pp. 127-129
Author(s):  
N.G. Klinova ◽  
◽  
I.N. Ivanova ◽  
V.V. Popov ◽  
V.I. Rusinov ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Chronic Urticaria ◽  
Skin Diseases ◽  
Lichen Ruber ◽  
Lichen Ruber Planus ◽  
Effect Of Therapy ◽  
Chronic Skin ◽  
Chronic Skin Diseases ◽  
Selection Of

The article is devoted to reflexotherapy of patients with different dermatoses. The experience of treatment with acupuncture of chronic skin diseases in reflexotherapy room is analised. The selection of acupuncture meridians and points in dermatological patients is proposed. The results of acupuncture of patients with lichen ruber planus, atopic dermatitis, eczema, chronic urticaria, prurigo, psoriasis of palms and soles, lichen ruber pillaris Devergy are discussed. Effect of therapy on basis of psychosomatic nature is explained.

scholarly journals ALLERGIC SKIN DISEASES AND SPORT

2012 ◽  
Vol 9 (5) ◽  
pp. 17-25
Author(s):  
N V Shartanova ◽  
O G Elisyutina ◽  
E S Fedenko ◽  
N I Ilina
Keyword(s):  
Physical Activity ◽  
Atopic Dermatitis ◽  
Skin Diseases ◽  
Elite Athletes ◽  
Skin Reactions ◽  
Immunological Mechanisms ◽  
Allergic Skin

According to various authors up to 25% of athletes suffer from allergies. In this review, we are talking about allergodermatoses. Various immunological mechanisms are underlying of skin reactions in elite athletes. Interesting facts about anaphylaxis, associated with physical activity and consumption of some food as well as about contact and atopic dermatitis are presented.

The prevalence of dogs with lymphocyte proliferative responses to food allergens in canine allergic dermatitis

2013 ◽  
Vol 16 (4) ◽  
pp. 735-739 ◽  
Author(s):  
K. Kawano ◽  
K. Oumi ◽  
Y. Ashida ◽  
Y. Horiuchi ◽  
T. Mizuno
Keyword(s):  
Atopic Dermatitis ◽  
Positive Result ◽  
Diagnostic Test ◽  
Skin Disease ◽  
Skin Diseases ◽  
Elimination Diet ◽  
Test Results ◽  
Food Allergens ◽  
Ige Antibodies ◽  
Allergic Skin

Abstract The aim of the present study was to examine the correlation between the results of lymphocyte proliferative test (LPT) specific to food allergens and allergic skin diseases in dogs. Investigations were performed in 138 dogs with allergic skin diseases diagnosed in a private animal hospital. Of the 138 animals, 97 cases had positive reactions in LPT specific to food allergens. Of these 97 dogs, 67 animals were diagnosed with canine atopic dermatitis (CAD), but 30 dogs did not have IgE antibodies to environmental allergens. As 14 dogs out of 30 animals showed a positive result, 12 dogs underwent elimination diet trial based on the test results and all of them showed improvement in the pruritus score. Therefore, we conclude that LPT is an effective diagnostic test for allergic skin disease. Results of the lymphocyte test are useful in the identification of food allergens for the elimination diet trial

scholarly journals Blastocystis hominis and allergic skin diseases; a single centre experience

2012 ◽  
Vol 2 (1) ◽  
pp. 66-69 ◽  
Author(s):  
Abdulla Muhammad Zaglool ◽  
Abdul Wahid Khodari ◽  
Usman Farooq
Keyword(s):  
Chronic Urticaria ◽  
Skin Diseases ◽  
Unknown Origin ◽  
Single Centre ◽  
Direct Examination ◽  
Blastocystis Hominis ◽  
Dermatology Clinic ◽  
Single Centre Experience ◽  
Allergic Skin ◽  
Stool Samples

Introduction: Blastocystis hominis in stool samples of individuals with allergic cutaneous symptoms were evaluated to study a possible link between them.Methods: The study was done from June 2010 to December 2011, in dermatology and parasitology department of central laboratory, Alnoor Specialist Hospital, Ministry of Health, Makkah, Saudi Arabia. A total of218 stool sample for patients who attended dermatology clinic and diagnosed as chronic urticaria, atopic dermatitis, or pruritus of unknown origin were included in the study. Standard laboratory tests for the detection of allergic etiology were performed for all patients. Detection of Blastocystis hominis has been made by microscopic examination of stool samples by direct examination and concentration technique.Results: Overall, 30(13.7%) stool samples were infected by Blastocystis hominis with age group (26-35) and male predominace 15(6.9%) and 18(8.2%), respectively. No other allergic cause of urticaria was discovered.Conclusion: Blastocystis hominis could be the etiology of chronic urticaria.

scholarly journals CONCENTRATIONS OF CYSTEINYL LEUKOTRIENES IN VARIOUS BIOLOGICAL FLUIDS OF CHILDREN WITH BRONCHIAL ASTHMA, ATOPIC DERMATITIS AND FOOD PROTEIN INDUCED ENTEROCOLITIS

2019 ◽  
Vol 4 ◽  
pp. 3-8
Author(s):  
Halyna Haiduchyk ◽  
Oleg Shadrin
Keyword(s):  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Skin Diseases ◽  
Rank Correlation ◽  
Control Group ◽  
Food Protein ◽  
Spearman Rank Correlation ◽  
Cysteinyl Leukotrienes ◽  
Spearman Rank ◽  
Allergic Skin

Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma, allergic rhinitis, atopic dermatitis, hives, allergic conjunctivitis, atherosclerotic cardio-vascular lesions system, inflammatory bowel disease, multiple sclerosis, cancer, etc. Better understanding of general pathophysiological mechanisms of allergic realization put the focus on the studying of cysteinyl leukotrienes biological effects in infants with atopic dermatitis and food-protein induced enterocolitis important. Aim. To optimize the diagnosis of allergic lesions of the gastrointestinal tract in children. Methods. The study was conducted in the allergy center and children clinic of the «Institute Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of NAMS of Ukraine». Children were included from September 2017 to June 2018. We examined 60 patients aged from 3 months to 3 years old, including 22 patients with atopic dermatitis, 18 children with food-protein induced enterocolitis, 8 patients with bronchial asthma in the stage of aggravation and 12 practically healthy children (control group). Medical examination have been perfomed, general IG E and specific serum IG E were defined by ImmunoCAP (Phadia, 100), as well as concentrations of cysteinyl leukotrienes (LTB4, LTC4, LTE4) in biological liquids (serum, saliva, urine) using immunoenzyme method using the production sets of the "Enzolifescience" (USA) company on the analyzer-photometer Multiskan Plus "Labsystems". The results of the received data were processed statistically. The probability of differences was estimated with Student’s t-test and Tau Kendall rank correlation test. The difference was considered significant at p <0.05. Results. A significant increase in the concentrations of cysteinyl leukotrienes (C4, D4, E4) in the blood, urine and saliva was found in infants with allergic skin diseases, gastro-intestinal and respiratory tract surveyed during manifestation the disease compared with the control group. Comparison of concentrations of leukotrienes in urine and saliva of children with atopic dermatitis (AD), food-protein induced enterocolitis (FPIE) and asthma did not find credible. However, in the serum of patients with asthma, the concentration of cysteinyl leukotrienes was significantly higher (703.9±68.7) pg / ml than in children with enterocolitis induced by dietary proteins (509.3±57.4) pg / ml and significantly did not differ from patients with atopic dermatitis (695.2±46.3) pg / ml. According to the results of Kendall Tau correlation test, no significant Spearman rank correlation was found between the cysteinyl leukotrienes concentration in blood and urine – r=0.14 (p>0.05), blood and saliva r=0.07 (p>0.05), urine and saliva r=–0.52 (p>0.05). Conclusions. Increase in cysteinyl leukotrienes concentrations in serum, urine and saliva of children of early age with allergic skin diseases, respiratory and gastrointestinal tract was found. The absence of significant Spearman rank correlation between concentrations of leukotrienes in blood and urine, blood and saliva, saliva and urine shows that it is possible to select any biological fluid, saliva or urine, as a non-invasive way to determine the leukotriene concentrations for monitoring activity of allergic inflammation.

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