scholarly journals "Validation of romanian version of visual analogue scale for irritable bowel syndrome questionnaire (VAS-IBS)"

2020 ◽  
Vol 84 (1) ◽  
pp. 63-68 ◽  
Author(s):  
Ioana-Miruna Balmus ◽  
Roxana Cojocariu ◽  
Alin Ciobîcă ◽  
Alina Cantemir ◽  
Cătălina Galățanu ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Irritable Bowel

scholarly journals Preliminary Study on the Tears Oxidative Stress Status and Sleep Disturbances in Irritable Bowel Syndrome Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Ioana-Miruna Balmus ◽  
Roxana-Oana Cojocariu ◽  
Alin Ciobica ◽  
Stefan Strungaru ◽  
Roxana Strungaru-Jijie ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Irritable Bowel Syndrome ◽  
Visual Analogue Scale ◽  
Quality Index ◽  
Analogue Scale ◽  
Sleep Disturbances ◽  
Oxidative Stress Status ◽  
Irritable Bowel ◽  
Age And Sex

According to the latest gastrointestinal disorders diagnostic criteria (ROME IV), the irritable bowel syndrome (IBS) is mainly characterized by the presence of abdominal pain and changes in intestinal transit. However, both sleep impairments and oxidative status changes (in patients’ sera, mucosal level, and other body fluids) were reported IBS. Thus, in this study, we aimed to evaluate several aspects regarding the oxidative stress status in patients’ tears as well as sleep disturbances by comparison with the intensity of IBS symptoms, as assessed by the visual analogue scale for irritable bowel syndrome (VAS-IBS). Ten IBS patients and fourteen healthy sex- and age-matched volunteers were recruited from the Oftaprof Ophthalmological Clinic (Iași, Romania). Visual analogue scale for irritable bowel syndrome and the Pittsburgh Sleep Quality Index (PSQI) questionnaires were administered to all the patients. Tear samples were collected using the Schirmer test procedure and were subjected to biochemical analysis—superoxide dismutase and glutathione peroxidase activities, malondialdehyde, and total soluble proteins levels were determined. Standard statistical analysis was applied. We found significant differences in oxidative stress marker dynamics in IBS patients as compared to healthy age- and sex-matched controls: increased superoxide dismutase activity (p=0.02), increased malondialdehyde (p=0.007), and total soluble proteins levels (p=0.019). We found no significant differences in tear glutathione peroxidase activity in IBS patients as compared to healthy age- and sex-matched controls (p=0.55). Furthermore, we observed that the oxidative stress tear markers are correlated with gastrointestinal symptoms severity (as evaluated by VAS-IBS) but not correlated to the sleep quality index and items (as evaluated by PSQI), with significant differences according to patient sex and IBS subtype stratification. In this way, this study brings additional evidence of the oxidative stress role in IBS pathology alongside the evaluation of tear fluid molecular dynamics in IBS for the first time in our best knowledge.

Further Validation of the Visual Analogue Scale for Irritable Bowel Syndrome After Use in Clinical Practice

2013 ◽  
Vol 36 (3) ◽  
pp. 188-198 ◽  
Author(s):  
Mariette Bengtsson ◽  
Jesper Persson ◽  
Kristina Sjölund ◽  
Bodil Ohlsson
Keyword(s):  
Irritable Bowel Syndrome ◽  
Clinical Practice ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Irritable Bowel

scholarly journals Evaluation of Non-Celiac Gluten Sensitivity in Patients with Previous Diagnosis of Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Crossover Trial

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 705 ◽  
Author(s):  
Michele Barone ◽  
Eugenio Gemello ◽  
Maria Teresa Viggiani ◽  
Fernanda Cristofori ◽  
Caterina Renna ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Challenge Test ◽  
Gluten Sensitivity ◽  
Gluten Free ◽  
Double Blind ◽  
Previous Diagnosis ◽  
Irritable Bowel ◽  
Fodmap Diet

Background. To date, there is no reliable marker for the diagnosis of non-celiac gluten sensitivity (NCGS), which benefits from a gluten-free diet (GFD). This condition is characterized by functional gastrointestinal symptoms similar to those occurring in the course of irritable bowel syndrome (IBS). However, IBS has a higher prevalence, and often benefits from the administration of a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet. The overlap of symptoms between these two pathologies has led to an overestimation of self-made diagnosis NCGS. Aims. To better identify NCGS in subjects with a previous diagnosis of IBS. Methods. All subjects received a low FODMAP diet that was also gluten-free (low FODMAP-GFD), and those presenting an improvement of symptoms were exposed to gluten or placebo (double-blind challenge with wash-out and crossover). The response to dietary treatments was evaluated by visual analogue scale (VAS). Results. Of 30 patients (23 women, seven men, aged 42.2 ± 12.5 years, body mass index (BMI) 24.7 ± 4.1 kg/m2), 26 benefited from the administration of low FODMAP-GFD and were exposed to the gluten/placebo challenge. After the challenge, using an increase of visual analogue scale VAS (Δ-VAS) ≥30%, 46.1% of the patients were NCGS+. However, this percentage became only 19.2% using a different method (mean ∆-VAS score plus two standard deviations). Conclusions. FODMAP intolerance could hide the response to a challenge test with gluten for the identification of NCGS in IBS patients. A low FODMAP-GFD followed by gluten/placebo challenge is able to identify patients with NCGS better. ClinicalTrials.gov registration number NCT04017585.

Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome

2016 ◽  
Vol 25 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Piero Portincasa ◽  
Leonilde Bonfrate ◽  
Maria Scribano ◽  
Anna Kohn ◽  
Nicola Caporaso ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Irritable Bowel Syndrome ◽  
Essential Oil ◽  
Analogue Scale ◽  
Irritable Bowel Syndrome Symptom ◽  
Symptom Severity Score ◽  
Syndrome Symptom ◽  
The Mean ◽  
Irritable Bowel

Background & Aims: Irritable Bowel Syndrome (IBS) patients still require effective treatment. The anti-inflammatory property of curcumin and the antispasmodic and carminative effect of fennel suggests that combination of these nutraceutical compounds would be useful in functional bowel disorders including IBS. We assessed the efficacy and tolerability of a combination of curcumin and fennel essential oil (CU-FEO) in IBS symptoms relief. Methods: 121 patients with mild-to-moderate symptoms of IBS defined by an Irritable Bowel Syndrome- symptom severity score (IBS-SSS) 100-300 and abdominal pain score 30-70 on a 100 mm Visual Analogue Scale (VAS), were randomly assigned to CU-FEO or placebo (2 capsules b.d. for 30 days). Primary endpoint was the mean decrease of IBS-SSS at the end of the treatment corrected for the mean baseline score (relative decrease). The impact of the treatment on quality of life was assessed through IBS-QoL questionnaire. Results: CU-FEO was safe, well-tolerated and induced symptom relief in patients with IBS; a significant decrease in the mean relative IBS-SSS was observed after 30 days of treatment (50.05 ± 28.85% vs 26.12 ± 30.62%, P<0.001). This result matched the reduction of abdominal pain and all the other symptoms of IBS-SSS. The percentage of symptom-free patients was significantly higher in the CU-FEO than in the placebo group (25.9% vs. 6.8%, P = 0.005). All domains of IBS-QoL improved consistently. Conclusion: CU-FEO significantly improved symptoms and quality of life in IBS patients over 30 days. Abbreviations: AEs: adverse events; CU-FEO: Curcumin-Fennel Essential Oil; GI: gastrointestinal; IBS: irritable bowel syndrome; IBS-D: irritable bowel syndrome-diarrhea; IBS-C: irritable bowel syndrome-constipation; IBS-SSS: Irritable Bowel Syndrome – symptom severity score; NF-kB: nuclear factor-κB; QoL: quality of life; UC: ulcerative colitis; VAS, Visual Analogue Scale.

Motor and sensory function of the rectum in different types of irritable bowel syndrome

2001 ◽  
Vol 120 (5) ◽  
pp. A399-A399
Author(s):  
J STEENS ◽  
P SCHAAR ◽  
C LAMERS ◽  
A MASCLEE
Keyword(s):  
Irritable Bowel Syndrome ◽  
Sensory Function ◽  
Different Types ◽  
Irritable Bowel
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