scholarly journals A REVIEW TO SUMMARIZE THE AVAILABLE EVIDENCES ON TURMERIC'S (CURCUMA LONGA) MEDICINAL PROPERTIES TO UNDERSTAND THE SCOPE OF ITS EFFICACY IN THE TREATMENT AND PREVENTION OF COVID19 DISEASES.

2020 ◽  
pp. 7-14
Author(s):  
Vd. Anagha Kothadia ◽  
Geeta D. Parulkar

The massive outbreak of coronavirus disease (COVID-19) across the world, has affected more than 200 countries and territories which was originated in bats and transmitted to humans through unknown intermediate hosts in the Wuhan seafood market, China, in December of 2019. Most people infected with the COVID-19 virus experience mild to moderate respiratory illness and recover without requiring special treatment. Older people, and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness. However, few broad-spectrum antiviral drugs have been evaluated against COVID-19 in clinical trials, resulted in clinical recovery. There is no system of medicine has any evidence-based treatment for COVID-19 yet and vaccine is recommended. WHO is helping to accelerate drug research. In India, Ministry of Ayush has issued guidelines which contain preventive and remedial information and advisories for the management of COVID19 symptoms. This review has assembled evidences of Turmeric/Curcuma longa which is one of the ingredient of the ayurvedic preventive majors issued by Ministry of Ayush and revealed various routes of administration of Turmeric /Curcuma longa asserted in Ayurvedic Texts as a remedy and additional preventive majors for COVID 19 symptoms.

2020 ◽  
pp. 74-79
Author(s):  
Om Joshi

Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus.Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people, and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness.Coronavirus disease (COVID-19) has taken so many innocent lives, as it spread most of the corner of the world and Gujarat, India oneof them. At present March 2020, most of the institutes and universities do ready to complete the course and repeats the topic in the classroom. As we know that, because of Coronavirus disease (COVID19)University Grants Commission, Health and Family Welfare Department and Education Department, Govt. of Gujaratinstructed to all the institutes and universities to remain closed till further instructions.In this period, researcher wishes to knowthe situation of the English language and literature classroom of Gujarat state. Researcher will refer the online circularsof different institutes and universities of Gujaratstate andwill do the telephonic interviews of English language teachers, based on the data, researcher will discuss the effects of Coronavirus disease (COVID-19) in English language and literature classroom.


Author(s):  
Chincholikar Sanjeev Vasantrao

Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. It has been declared a pandemic by the World Health Organization which exhibited human-to-human transmissibility and spread rapidly across countries. Older people, and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness. Climate, with temperature, humidity, Bacillus Calmette–Guérin (BCG) vaccination, immune status of persons, elderly people, uncontrolled co morbid conditions like heart diseases, diabetes mellitus, hypertension, kidney diseases seems to play an important role in spread and severity of corona virus infection. As reported from MOHFW website, the COVID-19 deaths are more in above 60 years of age with comorbidities cardiovascular disease, diabetes, chronic respiratory disease, and cancer.


2020 ◽  
Vol 6 (2) ◽  
pp. 100-107 ◽  
Author(s):  
Binay Sen ◽  
◽  

The novel coronavirus disease 2019 (COVID-19) is a pandemic health emergency, caused by the severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people and those with underlying some medical problems are more likely to develop serious illness. Considering different classical and contemporary viewpoints, the newly identified COVID-19 can be categorized under agantuja vyadhi (exogenous disease) by inception, caused by bhoota (organisms), and transforming to nija (endogenous) leading to disequilibrium of kapha, vata, and pitta doshas and manifestation of clinical features of mainly pranavaha (cardio-pulmonary system), rasavaha (cardio-vascular system) and raktavaha (vascular and RES) srotas dushti (vitiation of channels). In Ayurveda, for a new disease, the treatment principle is designed on the basis of the nature of the disorder, etiology and location. Hence rasayana drugs for epidemic disease, disinfectants for microorganism, dosha (mainly kapha and vata) pacifying drugs and disease-location specific treatment i.e deepana (stomachic), pachana (digestive), shwasahara (anti-dyspnea) and kasahara (anti-cough) are being discussed in this paper. Apart from this, potential of mukhavaishadyakara (mouth cleansing agent), patimarsha-nasya (nasal smearing), krimighna (anti-viral), vishaghna (anti-toxic) and kshara (alkali) dravya (medicinal plants) are being highlighted as these groups of drugs are effective in subsiding kapha, vata, killing microorganism and protecting ojas (immunity) by virtue of their broad spectrum pharmacodynamic properties.


2020 ◽  
Vol 44 (1) ◽  
pp. 75-79
Author(s):  
Huda S. Jassim

The objective of this review article was to discuss the interaction between virus effectiveness and host immune system challenges on the innate and adaptive on how the immune system able to defend against COVID-19 viral infections. Genetically, the COVID-19 is a virus that has genetic material coated by lipid with a crown of protein. The virus that causes COVID-19 is called severe acute respiratory syndrome coronavirus two (SARS-COV-2) and was first detected in humans last December 2019. Primarily, the COVID-19 virus spreads with droplets of saliva or nose discharge when an infected person sneezes or coughs. Most people with a healthy immune system those infected with the COVID-19 virus showed mild to moderate respiratory illness and recovered without needing special treatment. The aged people those had medical problems such as cardiovascular disease, diabetes, chronic respiratory disease, and cancer are most likely to develop serious illness. In-conclusion: Little is known about viral clearance, but regulation innate immune response associated with development of adaptive immunity neutralizing antibodies, memory T and B lymphocytes in convalescent patients raises hope for active immunization.


1970 ◽  
Vol 8 (2) ◽  
pp. 45-49
Author(s):  
Mahaveer Prasad Khinchi ◽  
Mohd. Shahid Khan ◽  
Simranjeet Singh Saluja

Coronavirus is found in animals and, rarely, can be transmitted from animals to humans and then spread person to person. An occurrence of the coronavirus infection (COVID-19) in China is causing global concern. It came from a seafood and meat market in Wuhan, China, in December 2019. It has since spread to many countries around the world including India. World Health Organization (WHO) declared novel coronavirus eruption a “pandemic” on March 11th, 2020. Patients infected with the COVID-19 virus will experience mild to moderate respiratory illness. Older people and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness. Prevent spread of infection by washing hands or using an alcohol based rub frequently and not touching face. This virus transmits primarily through droplets of saliva or discharge from the nose when adiseased person coughs or sneezes, so it’s important to cover face by mask and coughing into a flexed elbow at public places. Currently there are no specific vaccines or treatments for COVID-19. In this review, we summarize recent information about the emergence, tansmission, preventive measures and therapeutic options available now.    


Author(s):  
Arif S. Shekh ◽  
Jayshri V. Thorat ◽  
Aijaz A. Sheikh ◽  
K. R. Biyani

Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Most people infected with COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people and those with underlying medical problem like cardiovascular disease, Diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness. The best way to prevent and solve down transmission is to be well informed it causes and how it spread. Protect yourself and other from infection by washing your hands or using alcohol base rub frequently and not touching your face. The COVID-19 virus spread primarily through droplets of saliva or discharge from the nose when an infected person coughs or sneezes, so it’s important that you also practice respiratory etiquette (for ex. by coughing into a flexed elbow).The COVID-19 is a respiratory illness and the primary transmission of C0VID-19 route is through person to person contact and through when a contact infected person coughs or sneezes with respiratory droplets. No evidence of viruses that causes respiratory illness being transmitted via food or packaging. Corona viruses multiply in animal or human host, they cannot multiply in food.


2021 ◽  
Vol 5 (3) ◽  
Author(s):  
I Wayan Suryasa ◽  
María Rodríguez-Gámez ◽  
Tihnov Koldoris

The nurse has an important role caring for the patient infected with the coronavirus disease (COVID- 19). It is an infectious disease caused by the SARS-CoV-2 virus. The virus can spread from the mouth or nose of an infected person in small liquid particles when they cough, sneeze, speak, sing, or breathe. These particles range from larger respiratory droplets to smaller aerosols. It is important to practice respiratory etiquette, for example coughing into a flexed elbow, and to stay home and self-isolate until you recover if you feel unwell. Most people infected with the virus will experience mild to moderate respiratory illness and will recover without requiring special treatment. Older people and people with underlying medical conditions such as cardiovascular disease, diabetes, chronic respiratory disease, or cancer are more likely to develop serious illnesses. The goal of the research is to propose the best way to prevent and slow down transmission is to be well informed about the disease and how the virus spreads. Protect yourself and others from infection by staying at least 1 meter away from others, wearing a well-fitting mask, and washing your hands or using an alcohol-based rub frequently.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Priyanjali Bhattacharya ◽  
Trupti N. Patel

AbstractPlant derived products have steadily gained momentum in treatment of cancer over the past decades. Curcuma and its derivatives, in particular, have diverse medicinal properties including anticancer potential with proven safety as supported by numerous in vivo and in vitro studies. A defective Mis-Match Repair (MMR) is implicated in solid tumors but its role in haematologic malignancies is not keenly studied and the current literature suggests that it is limited. Nonetheless, there are multiple pathways interjecting the mismatch repair proteins in haematologic cancers that may have a direct or indirect implication in progression of the disease. Here, through computational analysis, we target proteins that are involved in rewiring of multiple signaling cascades via altered expression in cancer using various curcuma derivatives (Curcuma longa L. and Curcuma caesia Roxb.) which in turn, profoundly controls MMR protein function. These biomolecules were screened to identify their efficacy on selected targets (in blood-related cancers); aberrations of which adversely impacted mismatch repair machinery. The study revealed that of the 536 compounds screened, six of them may have the potential to regulate the expression of identified targets and thus revive the MMR function preventing genomic instability. These results reveal that there may be potential plant derived biomolecules that may have anticancer properties against the tumors driven by deregulated MMR-pathways.


Author(s):  
P. Srinivasa Rao ◽  
Pradeep Bheemavarapu ◽  
P. S. Latha Kalyampudi ◽  
T. V. Madhusudhana Rao

Background: Coronavirus (COVID-19) is a group of infectious diseases caused by related viruses called coronaviruses. In humans, the seriousness of infection caused by a coronavirus in the respiratory tract can vary from mild to lethal. A serious illness can be developed in old people and those with underlying medical problems like diabetes, cardiovascular disease, cancer, and chronic respiratory disease. For the diagnosis of the coronavirus disease, due to the growing number of cases, a limited number of test kits for COVID-19 are available in the hospitals. Hence, it is important to implement an automated system as an immediate alternative diagnostic option to pause the spread of COVID-19 in the population. Objective: This paper proposes a deep learning model for classification of coronavirus infected patient detection using chest X-ray radiographs. Methods: A fully connected convolutional neural network model is developed to classify healthy and diseased X-ray radiographs. The proposed neural network model consists of seven convolutional layers with rectified linear unit, softmax (last layer) activation functions and max pooling layers which were trained using the publicly available COVID-19 dataset. Results and Conclusion: For validation of the proposed model, the publicly available chest X-ray radiograph dataset consisting COVID-19 and normal patient’s images were used. Considering the performance of the results that are evaluated based on various evaluation metrics such as precision, recall, MSE, RMSE & accuracy, it is seen that the accuracy of the proposed CNN model is 98.07%.


2013 ◽  
pp. 372-397
Author(s):  
Keith T. Palmer ◽  
Paul Cullinan

Respiratory illnesses commonly cause sickness absence, unemployment, medical attendance, illness, and handicap.1 Collectively these disorders cause 19 million days/year of certified sickness absence in men and 9 million days/year in women (with substantial additional lost time from self-certified illness) and, among adults of working age, a general practitioner consultation rate of 48.5 per 100/year with more than 240 000 hospital admissions/year. Prescriptions for bronchodilator inhalers run at some 24 million/year, and mortality from respiratory disease causes an estimated loss of 164 000 working years by age 64 and an estimated annual production loss of £1.6 billion (at prices in 2000). Respiratory disease may be caused, and pre-existing disease may be exacerbated, by the occupational environment. More commonly, respiratory disease limits work capacity and the ability to undertake particular duties. Finally, individual respiratory fitness in ‘safety critical’ jobs can have implications for work colleagues and the public. Within this broad picture, different clinical illnesses pose different problems. For example, acute respiratory illness commonly causes short-term sickness absence, whereas chronic respiratory disease has a greater impact on long-term absence and work limitation; and the fitness implications of respiratory sensitization at work are very different from non-specific asthma aggravated by workplace irritants. Occupational causes of respiratory disease represent a small proportion of the burden, except in some specialized work settings where particular exposures give rise to particular disease excesses. The corollary is that the common fitness decisions on placement, return to work, and rehabilitation more often involve non-occupational illnesses than occupational ones. By contrast, statutory programmes of health surveillance focus on specific occupational risks (e.g. baking) and specific occupational health outcomes (e.g. occupational asthma). In assessing the individual it is important to remember that respiratory problems are often aggravated by other illnesses, particularly disorders of the cardiovascular and musculoskeletal systems.


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