scholarly journals KHASIAT MADU PADA PENYEMBUHAN LUKA KULIT

2013 ◽  
Vol 4 (3) ◽  
Author(s):  
Sonny J R Kalangi
Keyword(s):  
Wound Healing ◽  
Topical Application ◽  
Microbial Growth ◽  
Healing Process ◽  
High Viscosity ◽  
Wound Healing Process ◽  
Physical Barrier

Abstract: The topical application of honey on a wound is effective in controlling the wound healing process and results in clean granulation tissues in the wound base. Honey acts as a hyperosmolar medium and prevents microbial growth. Besides that, honey has a high viscosity that forms a physical barrier and cretaes a wet environmet which is very effective in accelerating wound healing. Nutrients in honey increase the supply of local substances that might be useful in reepithelization. In addition, honey contains a catalase enzyme that can influence wound healing.Keywords: honey, wound healingAbstrak: Pemberian madu topikal efektif dalam mengontrol dan menghasilkan dasar luka bergranulasi bersih. Madu bekerja terutama sebagai medium hiperosmolar dan mencegah pertumbuhan bakteri. Madu juga memiliki viskositas tinggi yang membentuk sawar fisik dan menciptakan lingkungan basah; sifat tersebut yang membantu dan mempercepat penyembuhan luka. Kandungan bahan makanan dari madu menambah pasokan bahan lokal yang mungkin membantu mempercepat reepitelisasi. Disamping itu, madu mengandung enzim katalase yang juga mempengaruhi proses penyembuhan luka.Kata kunci: madu, penyembuhan luka

scholarly journals The Effect Of Giving Honey on The Process of Wound Healing in Burned Patients

2021 ◽  
Vol 5 (1) ◽  
pp. 51-56
Author(s):  
Intan Pramesty
Keyword(s):  
Staphylococcus Aureus ◽  
Wound Healing ◽  
Healing Process ◽  
Health Sector ◽  
Antimicrobial Properties ◽  
High Viscosity ◽  
Low Ph ◽  
Wound Healing Process ◽  
Burn Patients ◽  
Ph Level

Backgroud: Burns are one of the most dangerous injuries and the main cause of disability to death. Burns can be interpreted as one of the serious problems in society and are recorded to cause around 265,000 deaths each year. Honey can maintain the wound condition to keep it moist and in high viscosity to prevent infection. Method: This study was conducted to determine the effect of honey on the wound healing process in burn patients. This study uses a literature review method. The population in this study is a journal with a background in the health sector with 10 international journals on burns with the qualifications of 9 SCIMAGO indexed journals and 1 SINTA indexed journal published from 2015 to 2020. Results: Burns that treated in the form of pure honey can generate good results and heal in an average of 20 days. The healing process will be better, if the wound given a mixture of other ingredients which also have a low acidity such as garlic, chitosan and beeswax and olive oil. Honey has antimicrobial properties and a low pH level. The microbe most sensitive to honey is Staphylococcus aureus. Conclusion: The conclusion from this study, honey can be used as an alternative treatment for burns.

scholarly journals Efek aplikasi topikal gel ekstrak pandan wangi terhadap penyembuhan luka gingiva

2017 ◽  
Vol 2 (2) ◽  
pp. 53
Author(s):  
Icha Nofikasari ◽  
Afifah Rufaida ◽  
Chynintia Dewi Aqmarina ◽  
Failasofia Failasofia ◽  
Annisa Rahmi Fauzia ◽  
...  
Keyword(s):  
Wound Healing ◽  
Blood Vessel ◽  
Topical Application ◽  
Healing Process ◽  
Punch Biopsy ◽  
Positive Control ◽  
Negative Control ◽  
Wound Healing Process ◽  
Wound Area ◽  
Pandanus Amaryllifolius

The Effect of topical application pandan extract gel on gingival wound. Post-gingivectomy wound is usually covered by periodontal dressing, which generally contains some chemical compounds to protect the wound. However, it can provide allergic effect on some patients. Pandan leaves (Pandanus amaryllifolius Roxb.) contain a number of active substances that have anti-inflammatory, antioxidant and antibacterial effect and play a role in wound healing. This study aims to determine the effect of topical application of Pandan leaf extract gel on gingival wound healing. Gingivectomy model was carried out on mandibular incisive gingival using the 2.5-mm punch biopsy. Thirty-six rats were randomly divided into 3 groups of treatment: negative control (CMC-Na), positive control (Aloclair), and 50% of pandan extract gel. The gels on each group were applied (twice in a day) to the wound area after gingivectomy. The observation of the wound healing process was also carried out on day 1, 3, 7, and 14 by making the histological preparations of gingival wound area. The number of blood vessels was observed using microscope and data was analysed using Two- Way Anova and LSD. The result showed that number of blood vessel increased on day 3 and the peak was on day 7. Anova and LSD test showed several significant differences comparison the number blood vessel between treatment and control. In conclusion, topical application Pandan leaves extract gel could accelerate gingival wound healing.ABSTRAKLuka pasca gingivektomi dibalut dengan periodontal dressing yang mengandung senyawa kimia dengan tujuan melindungi luka, namun senyawa kimia periodontal dressing yang ada di pasaran dapat menimbulkan efek alergi terhadap beberapa pasien. Daun pandan wangi (Pandanus amaryllifolius Roxb.) mengandung zat aktif yang memiliki anti inflamasi, antioksidan, dan antibakteri kemungkinan berperan dalam proses penyembuhan luka. Penelitian ini bertujuan untuk mengetahui peran gel ekstrak daun pandan wangi dalam proses penyembuhan luka pasca gingivektomi pada tikus wistar melalui pengamatan jumlah pembuluh darah. Model gingivektomi dilakukan pada gingiva incisivus mandibula dengan menggunakan punch biopsy diameter 2,5 mm. Tiga puluh enam tikus dibagi secara acak ke dalam 3 kelompok perlakuan yaitu kontrol negatif (Gel CMC-Na), kontrol positif (Aloclair), dan gel ekstrak pandan wangi 50%. Gel uji pada masing- masing kelompok diaplikasikan pada area luka pasca gingivektomi dua kali sehari. Pengamatan proses penyembuhan luka dilakukan pada hari ke 1, 3, 7, dan 14 dengan membuat preparat histologi gingiva area luka. Parameter penyembuhan luka yang diamati adalah jumlah pembuluh darah. Data jumlah pembuluh darah dianalisis dengan menggunakan uji statistik parametrik. Hasil penelitian menunjukkan jumlah pembuluh darah mengalami peningkatan mulai hari ke-3 dan mencapai puncaknya pada hari ke-7. Hasil uji two way Anova menunjukkan adanya perbedaan yang bermakna rerata jumlah pembuluh darah antar kelompok perlakuan dengan kontrol positif maupun negatif (p<0,05). Hasil uji LSD juga menunjukkan perbedaan yang bermakna perbandingan kelompok kontrol dan perlakuan pada semua hari pengamatan. Kesimpulan penelitian ini adalah gel ekstrak pandan wangi 50% dapat mempercepat proses penyembuhan luka pasca gingivektomi dengan kemampuannya meningkatkan jumlah pembuluh darah.

scholarly journals Topical application of silver-curcumin on wound healing in rabbits

2016 ◽  
Vol 32 (2) ◽  
pp. 55-64
Author(s):  
R Islam ◽  
UK Rima ◽  
MM Haq ◽  
MM Hossain ◽  
MM Rahman ◽  
...  
Keyword(s):  
Wound Healing ◽  
Connective Tissue ◽  
Topical Application ◽  
Healing Process ◽  
Silver Sulfadiazine ◽  
Wound Management ◽  
Control Group ◽  
Wound Healing Process ◽  
Fibrous Connective Tissue ◽  
Positive Effects

Curcumin, a natural product obtained from the rhizomes of Curcuma longa, is used traditionally in prevention of wound infection. To determine the effects of silver and curcumin combination on surgical wound healing, a study was conducted in rabbits. A total of 32 surgical wounds were created in 16 rabbits in four groups. Information was recorded from Day 0 to Day 42 postoperatively. Swelling area of wound, elevation of suture line from the skin surface, width of sutured area and contraction length were recorded weekly. Treatment with curcumin, 1% silver sulfadiazine (1% SSD) and a mixture of the two resulted in swelling of 11.4 ± 0.1 mm, 11.1 ± 0.4 mm and 11.0 ± 0.1 mm, respectively. Swelling (12.2 ± 0.3mm) and elevation of sutured line was higher (3.4 ± 0.2 mm) in wounds of control group and lower (2.3 ± 0.1 mm) in wounds treated with a mixture of curcumin and 1% SSD. The scores of wound colonization were lowest (0.8) in 1% SSD group followed by mixture of curcumin and 1% SSD (1.0), curcumin (1.3) and tincture of benzoin (1.6) alone. Histopathologically reactive cells decreased markedly in wounds treated with combination of 1% SSD and curcumin at D3 with increased fibrous connective tissue. However, wounds treated with 1% SSD showed fewer reactive cells than curcumin group. Proliferation of fibrous connective tissue was highest in the silver treated wound, which indicates good wound healing process. Overall, wound healing was improved by the topical application of 1% SSD alone. Curcumin had positive effects on wound healing process but less than 1% SSD. These results indicate that 1% silver sulfadiazine is the best topical therapy for wound management in rabbits.Bangl. vet. 2015. Vol. 32, No. 2, 55-64

scholarly journals Effect of Topical Application of Binahong [Anredera cordifolia (Ten.) Steenis] Leaf Paste in Wound Healing Process in Mice

2014 ◽  
Vol 1 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Gurwinder Kaur a/p Gurcharan Singh ◽  
Novi Vicahyani Utami ◽  
Hermin Aminah Usman
Keyword(s):  
Wound Healing ◽  
Topical Application ◽  
Healing Process ◽  
Wound Healing Process

scholarly journals Evaluation of the alcoholic extract of Dipteryx alata Vogel almonds and bark in skin wound healing in C57BL6 mice

2021 ◽  
Vol 73 (6) ◽  
pp. 1315-1322
Author(s):  
M.C.P. Gouveia ◽  
B.W. Minto ◽  
L.F. Sargi ◽  
R.L. Souza ◽  
J.M. Pazzini ◽  
...  
Keyword(s):  
Wound Healing ◽  
Topical Application ◽  
Healing Process ◽  
Skin Wound ◽  
Bark Extract ◽  
Wound Healing Process ◽  
Alcoholic Extract ◽  
Skin Wound Healing ◽  
Significant Difference ◽  
Dipteryx Alata

ABSTRACT The aim of this study was to evaluate the topical application of alcoholic extracts of Dipteryx alata Vogel almonds and bark in skin wound healing in mice. Fifty-four C57BL/6 mice were equally distributed into three groups: Control, Almond, and Bark. A 9 mm skin fragment was resected from the dorsal region of the animals’ thorax. The wounds were submitted to topical application of base cream (vehicle), 10% hydroalcoholic almond extract, or bark extract twice a day. Macroscopic, histological, and immunohistochemical evaluations were conducted on the 7th, 14th, and 21st postoperative days. No significant difference was observed regarding skin wound area among groups, with the parameter presenting only a temporal effect on healing (p>0.05). The almond and control groups exhibited more intense collagenization than the bark group (p<0.05). Dipteryx alata Vogel showed to be inert in the wound healing process in mice.

scholarly journals Healing Efficacy of an EGF Impregnated Triple Gel Based Wound Dressing: In Vitro and In Vivo Studies

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Najmeh Khanbanha ◽  
Fatemeh Atyabi ◽  
Azade Taheri ◽  
Fatemeh Talaie ◽  
Mirgholamreza Mahbod ◽  
...  
Keyword(s):  
Wound Healing ◽  
Topical Application ◽  
Healing Process ◽  
Tissue Growth ◽  
In Vivo Studies ◽  
Wound Healing Process ◽  
Beneficial Effects ◽  
Linear Viscoelastic

To accomplish an ideal wound healing process which promotes healthy tissue growth with less scaring, a novel gel based topical drug delivery system composed of 3 different polymers chitosan, dextran sulfate, and polyvinylpyrrolidone K30 (CDP) was prepared. The physicochemical properties of the prepared gels were investigated in vitro. Gels showed a maximum swelling ratio of 50 ± 1.95 times of dried gel in PBS at pH 7.4. The swelling ratios increase in acidic and alkaline pH to 55.3 ± 1.75 and 65.5 ± 2.42, respectively. In the rheological test, prepared gels revealed viscoelastic properties and a small linear viscoelastic region of 0.166%. In vivo wound healing promoting activities of CDP gels containing 20 μg/mL EGF were evaluated on surgically induced dermal wounds in rats using pathologic examination. The application of CDP gel with incorporated EGF significantly reduced the defect on the rat’s skin and enhanced epithelial healing compared with the topical application of the EGF-free CDP gel. The results clearly substantiate the beneficial effects of the topical application of CDP containing EGF in the acceleration of healthy wound healing process with less scarring.

scholarly journals Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process

2017 ◽  
Vol 22 (2) ◽  
pp. 103
Author(s):  
Kintoko Kintoko ◽  
Hanifah Karimatulhajj ◽  
Trie Yuni Elfasyari ◽  
Ersi Arviana Ihsan ◽  
Teguh Adiyas Putra ◽  
...  
Keyword(s):  
Wound Healing ◽  
Blood Glucose ◽  
Topical Application ◽  
Healing Process ◽  
Ethanolic Extract ◽  
Positive Control ◽  
Diabetic Rats ◽  
Wound Healing Process ◽  
Diabetic Ulcers ◽  
Control Diabetes

Diabetes mellitus (DM) is a metabolic disease which is becoming the first number of health problem in Indonesia, based on the results of the Basic Health Research of Ministry of Health in 2013. One of the diabetes complications affected by high levels of blood glucose is diabetic ulcers wich 85% the number of cases was overed by amputation as the result of improper handling. Herbal treatments could be an alternative treatment of diabetic ulcers, one of them is binahong plant. The results of previous studies have shown the ability of ethanolic extract of binahong leaf in accelerating wound healing in diabetic rats. This study would be a continued study to test five kinds of binahong leaf fractions (FDB) with gradual solvent polarity in accelerating wound healing in diabetic ulcer. Wound healing parameters observed were percentage of wound healing from the wound diameter contraction. The test begins with ethanolic extract of binahong leaf fractionation to produce fractions of hexane (FHDB), chloroform (FKDB), ethyl acetate (FEADB), and ethanol (FEDB). Water fraction (FADB) was obtained from ethanolic leaf extract residues of binahong leaf extraction. Each fraction activity was tested topically twice daily on dorsal of test animals that created wounds using a punch biopsy 5 mm diameters. Grouping of test animals were divided into 13 groups with normal control group (non diabetes), negative control (diabetes + topical application of biocream®), positive control (diabetes + topical application of madecassol), and 10 diabetes groups with topical application of 5 kinds of binahong leaf fractions with each fractions consist of a concentrations of 5% and 10% with biocream® as a vehicle. Diabetic parameters measured include blood glucose levels (KGD) and weight lost percentage (PB%) in day 1 and 10 during a 10-day treatment. The results showed the influence of KGD in the condition of diabetes on wound healing rats diabetic ulcers which topically treated with binahong leaf fractions. FADB 10% has significant differences potention in wound healing process in diabetic rats macroscopically that accelerates wound contraction compared with negative and positive control groups (p<0,05).

HUBUNGAN MOBILISASI DINI TERHADAP PENYEMBUHAN LUKA POST OPERASI SECTIO CESARIA

2019 ◽  
Vol 2 (1) ◽  
pp. 14-17
Author(s):  
Nurul Aini Siagian ◽  
Syafira Nusaibah ◽  
Andayani Boang Manalu
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Early Mobilization ◽  
Sectio Caesarea ◽  
Wound Healing Process ◽  
P Value ◽  
Cross Sectional ◽  
Care Services ◽  
Healing Wound ◽  
Rapid Healing

Early mobilization includes factors that can affect the process of wound healing after surgery. Immediate mobilization in stages is very useful for the process of healing wounds and preventing infection and venous thrombosis. The purpose of this study was to determine whether there is a relationship between early mobilization and the process of healing wound post operative sectio caesarea at Sinar Husni General Hospital Medan Helvetia. The research design used was analytic survey with cross sectional approach. The sample in this study used the Consecutive Sampling method of data collection using a checklist sheet conducted on a sample of 19 respondents. The results of the study in this study are the majority of respondents who did early mobilization and who experienced rapid wound healing process as many as 4 people (21%) while the minority of respondents who did early mobilization and who experienced slow wound healing process were 1 person (5.3%). The majority of respondents who did not mobilize early and who experienced a slow wound healing process were 11 people (57.9%) and a minority who did not mobilize early and who experienced rapid healing as many as 4 people (21.1%). Statistical test results obtained p value = 0.046 <0.005. The conclusions of the results of this study indicate there is a relationship between early mobilization and the process of healing post operative sectio of caesarea. Suggestions The results of this study can be applied as a reference to improve nursing care services, especially in providing counseling and assistance to patients.

Hubungan Status Gizi Dengan Proses Penyembuhan Luka Di Rsud H. Andi Sulthan Daeng Radja Kabupaten Bulukumba

2017 ◽  
Vol 2 (1) ◽  
pp. 20-28
Author(s):  
Fitriani ◽  
Tenriwati
Keyword(s):  
Wound Healing ◽  
Nutritional Status ◽  
Healing Process ◽  
Data Retrieval ◽  
Observational Research ◽  
Wound Healing Process ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

At present, the incidence of injuries in Indonesia is quite high, as seen from data on traffic accidents in the general public. There are several factors that affect wound healing, one of which is nutritional status. Based on the preliminary data retrieval conducted by researchers in the seruni surgery room in the last 1 month namely in March, it was found that the number of wounded patients was 109 patients, where the number of men was 78 (71.56%) while the number of women was 31 ( 28.44%) The purpose of this study was to determine the relationship between nutritional status and the wound healing process in RSUD. H. Andi. Sulthan Daeng Radja Kab. Bulukumba. This research uses the type of design of this research is quantitative research. This type of research uses analytic observational research with cross sectional approach. The sample of this study were 41 respondents taken by purposive sampling method. Data analysis in this study used the chi-square test (chi square test). The results of the analysis used the chi-square statistical test with a confidence level (α = 0.05). Based on the results of this test, the p value is 0.001, thus p <α (0.001 <0.05), then Ho is rejected and Ha is accepted. The conclusion of this study is that there is a relationship between nutritional status and the process of wound healing in RSUD. H. Andi. Sulthan Daeng Radja Kab. Bulukumba. Researchers suggest that this study be used as a material consideration in the fulfillment of nutrition in wound care patients in RSUD.H.A. Sulthan Daeng Radja Kab. Bulukumba and this research can be continued by conducting research related to the wound healing process and linking it with other variables.

Sign in / Sign up

Export Citation Format

Share Document