scholarly journals Frequency and Antibiotic Susceptibility of Pseudomonas aeruginosa and Acinetobacter baumannii Infections in Pediatrics Intensive Care Unit of Imam Ali Hospital, Karaj, Iran During 2017- 2018

2020 ◽  
Vol 8 (1) ◽  
pp. 15-18
Author(s):  
Reza Arjmand ◽  
Kumars Porrostami ◽  
Seyedeh Sana Esteghamat ◽  
Pouria Chaghamirzayi ◽  
Parastoo Sharifian ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Acinetobacter Baumannii ◽  
Nosocomial Infections ◽  
Antibiotic Susceptibility ◽  
Test Method ◽  
Susceptibility Pattern ◽  
Antibiotic Susceptibility Pattern ◽  
Microbiological Methods

Background: Pseudomonas aeruginosa and Acinetobacter baumannii are widely ubiquitous in nature. In addition, they are opportunistic pathogens for humans and the common cause of nosocomial infections. Objective: Due to the increased antibiotic resistance in the treatment of nosocomial infections, this study aimed to evaluate the antibiotic susceptibility pattern of P. aeruginosa and A. baumannii in the pediatrics intensive care unit (PICU). Materials and Methods: Totally, 280 clinical samples from PICU patients were evaluated in this study. The samples were examined for P. aeruginosa and A. baumannii using standard microbiological methods. Finally, the Epsilometer test method was performed to investigate the antibiotic susceptibility pattern of these bacteria. Results: The results revealed a total of 21 isolates (7.5%) of P. aeruginosa and 11 isolates (3.9%) of A. baumannii. P. aeruginosa isolates showed the highest susceptibility to colistin (85.7%) and gentamicin (66.7%) while A. baumannii isolates were more susceptible to colistin (100%), ceftazidime (54.5%), and amikacin (45.5%), respectively. Conclusion: Due to the antibiotic susceptibility patterns of bacterial isolates in the recent study, colistin and gentamicin are recommended for the treatment of P. aeruginosa infections and colistin, ceftazidime, and amikacin are suggested for A. baumannii infections.

scholarly journals Microbial infection and antibiotic patterns among intensive care unit patients in a tertiary hospital in Central Nepal

2013 ◽  
Vol 8 (3) ◽  
pp. 1-8
Author(s):  
RK Sanjana ◽  
PC Majhi
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Antibiotic Susceptibility ◽  
Tertiary Care ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Microbial Infection ◽  
Laboratory Procedure ◽  
Antibiotic Susceptibility Pattern

Aims The present study is a fundamental effort to evaluate the bacteriological and antibiotic patterns in the Intensive Care Unit (ICU) setting in a tertiary care hospital. This study was carried out to guide the clinician in choosing the appropriate antibiotics and to prevent emergence of multidrug resistance bacteria. Materials and Methods Between March 2009 to Feb 2012, the samples from various ICUs that were submitted to the microbiology laboratory for culture and sensitivity were included in this study. All the organisms were identified morphologically and biochemically by standard laboratory procedure and antibiotic susceptibility pattern was determined by disc diffusion methods. Result Of 3,780 specimens, 2,312 (61.1%) isolates were recovered. Single organisms were isolated from 1,746 (75.5%) samples while the remaining 566 (24.4%) had two or more organisms isolated. Pseudomonas aeruginosa was the most common isolate 819 (35.4%), followed by Klebsiella pneumoniae 637 (27.5%). Antibiotics sensitivity of Pseudomonas aeruginosa showed that almost all isolates were resistant to cephalexin (97.8%) and ciprofloxacin (80.3%). However (95.8%) of the isolates were sensitive to tobramycin, (92.0%) to meropenem & (74.80 %) to amikacin. Conclusion It is concluded that Pseudomonas aeruginosa is the predominate pathogen isolated from ICUs of this Hospital. Most of the frequently isolated pathogens are resistant to cephalosporins and quinolone antibiotics as compared to aminoglycosides and carbapenem. Regular surveillance of antibiotic susceptibility pattern is very important for setting a guideline to the clinician in choosing an appropriate therapy of infected patients of ICUs. Journal of College of Medical Sciences-Nepal, 2012, Vol-8, No-3, 1-8 DOI: http://dx.doi.org/10.3126/jcmsn.v8i3.8678

scholarly journals Bacterial Isolates and its Antibiotic Susceptibility Pattern in NICU

2014 ◽  
Vol 11 (1) ◽  
pp. 66-70 ◽  
Author(s):  
S Shrestha ◽  
NC Shrestha ◽  
S Dongol Singh ◽  
RPB Shrestha ◽  
S Kayestha ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Gram Positive ◽  
Antibiotic Susceptibility Pattern ◽  
Gram Negative ◽  
Nosocomial Sepsis

Background Neonatal sepsis is one of the major causes of morbidity and mortality among the newborns in the developing world. Objectives To determine the common bacterial isolates causing sepsis in neonatal intensive care unit and its antibiotic susceptibility pattern. Methods A one year discriptive prospective study was conducted in neonatal intensive care unit to analyse the results of blood culture and to look into the sensitivity of the commonly used antibiotics. Results The blood culture yield by conventional method was 44.13% with nosocomial sepsis accounting for 10.79%. 84.08% were culture proven early onset sepsis and 15.95% were late onset sepsis. Klebsiella infection was the commonest organism isolated in early, late and nosocomial sepsis but statistically not significant. Gram positive organisms were 39.36% in which Staphylococcus aureus was the leading microorganism followed by coagulase negative staphylococcus areus. Gram negative organisms were 60.64% amongst them Klebsiella was the most often encountered followed by Pseudomonas. The most common organism Klebsiella was 87.5% and 78.3% resistance to ampicillin and gentamycin respectively. Among gram negative isolates 87.5% and 77.2% were resistance to ampicillin and gentamycin respectively. Among gram positive isolates 58.5% and 31.5% resistance were noted to ampicillin and gentamycin respectively. Resistance to cefotaxim to gram negative and gram positive isolates were 87.34% and 59.35% respectively. Conclusion Klebsiella is most common organism which is almost resistance to first line antibiotics. Resistance to both gram negative and gram positive isolates among firstline antibiotics and even with cefotaxim is emerging and is a major concern in neonatal intensive care unit. DOI: http://dx.doi.org/10.3126/kumj.v11i1.11030 Kathmandu University Medical Journal Vol.11(1) 2013: 66-70

Epidemiology of Nosocomial Outbreaks: 14-Year Experience at a Tertiary-Care Center

2000 ◽  
Vol 21 (8) ◽  
pp. 527-529 ◽  
Author(s):  
Luis Ostrosky-Zeichner ◽  
Rosa Baez-Martinez ◽  
M. Sigfrido Rangel-Frausto ◽  
Samuel Ponce-de-León
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Nosocomial Infections ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Common Organism ◽  
Overall Mortality

Twelve nosocomial outbreaks over 14 years at a tertiary-care center in Mexico are described. Overall mortality was 25.8%, one half due to pneumonia. The most common organism was Pseudomonas aeruginosa. Incidence was three outbreaks per 10,000 discharges; outbreak-related infections comprised 1.56% of all nosocomial infections. Incidence in the intensive care unit was 10-fold higher.

Biofilm formation, antibiotic susceptibility and RAPD genotypes in Pseudomonas aeruginosa clinical strains isolated from single centre intensive care unit patients

2017 ◽  
Vol 62 (6) ◽  
pp. 531-538 ◽  
Author(s):  
Martina Vaněrková ◽  
Barbora Mališová ◽  
Iva Kotásková ◽  
Veronika Holá ◽  
Filip Růžička ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Pseudomonas Aeruginosa ◽  
Intensive Care ◽  
Antibiotic Susceptibility ◽  
Biofilm Formation ◽  
Single Centre ◽  
Clinical Strains
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