INTESTINAL PARASITE INFECTION, CHANGE OF COMPLETE BLOOD COUNT BEFORE AND AFTER TREATMENT, RELATED FACTORS OF PATIENT IN HUE UNIVERSITY HOSPITAL

2017 ◽  
pp. 62-68
Author(s):  
Xuan Tuan Anh Dinh ◽  
Nu Phuong Anh Ton
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Intestinal Parasite ◽  
Clonorchis Sinensis ◽  
Parasite Infection ◽  
Trichuris Trichiura ◽  
University Hospital ◽  
Intestinal Helminth ◽  
Mild Anemia ◽  
Parasite Infections

Introduction: Intestinal parasite infections still are very common in Vietnam and have special cause serious consequences for human health. Mastery on the prevalence of them should be done. Materials and methods: A cross session with monitoring study were carried out to use the wet mount direct examination, Kato technique and the complete blood count for evaluation the rate of intestinal parasite infections in 590 patients attending to the Parasitology Department in Hue University Hospital. We also interviewed them to reveal their life’s hygienic condition, knowledge and risk behaviour of intestinal parasite infections. Result: The rate of soil transmitted intestinal helminth was 14.1%. Primarily, patients were infected: hookworm (8.5%), Trichiuris trichiura (4.3%) and then Clonorchis sinensis 0.9%. Being 100% of patients infected with Clonorchis sinensis had eosinophile increased and decreased significantly after 1 month of treatment response. Being 53% of patients infected with hookworm and/or Trichuris trichiura had eosinophils increased, and decrease to the normal after 1 month of treatment response. Only patients, who were infected with hookworm and/or Trichiuris trichiura, had a mild anemia, the rate of cases had mild anemia: hookworm 18.8%, Trichuris trichiura 13.3%. The rate of risk behavior of intesstinal parasite infection were: no hand washing before eating and after defecation, unregular anthelmintic treatment, eating raw beef, pork, and fish. Conclusion: Intestinal parasite infections in patients attending to the Hue University Hospital were mainly hookworm, Trichuris trichiura and Clonorchis sinensis. Increasing the eosinophils or decreasing the hemoglobin values or mild anemia is the signs of intestinal parasitic diseases. To prevention of intestinal helminth infection, it should be eating well cooking dishes, washing hands totally and regular anthelmintic treatment. Key words: Nematodes, trematodes, eosinophilia, anemia

INTESTINAL PARASITE INFECTION IN HUE UNIVERSITY HOSPITAL IN 2013-2014 BY DIRECT EXAMINATION AND IMMUNOLOGICAL DIAGNOSTICS

2016 ◽  
pp. 105-111
Author(s):  
Nu Phuong Anh Ton ◽  
Thi Minh Chau Ngo
Keyword(s):  
Intestinal Parasite ◽  
Intestinal Parasites ◽  
Clonorchis Sinensis ◽  
Taenia Solium ◽  
University Hospital ◽  
High Rate ◽  
Intestinal Helminth ◽  
Direct Examination ◽  
Life Condition ◽  
Parasite Infections

Introduction: Intestinalparasite infections still are very common in tropical country such as Vietnam. Therefore evaluation of the prevalence of them should be done. Materials and methods: A crosssectional descriptivestudy were carried out to use the wet mount direct examination, Kato and ELISA technique for evaluation the rate of intestinal parasite infections, interviewed them to reveal their life’s hygenic condition, knowledge and risk behaviour of intestinal parasite infections in 640 patients attending to the in Hue University of hospital. Result: The rate of soiltransmitted intestinal helminth were lower than the foodborne infection of cestode and trematode such as: Taenia solium/saginata 3.64%, Clonorchis sinensis 2.73%. The rate of positive antibody of rare intestinal parasite were Fasciola gigantica 40.68%, E. histolytica/dispar 43.75%, Toxocara canis 32.43%, Gnasthostoma spinigerum 37.5%, Taenia solium 51.43%, Strongyloidesstercoralis 16.67%. Most of people has hygenic life condition with hygenic water available. The popular knowledge of intestinal parasite diseases of transmission, pathology, prevention and treatment were concentrate on oiltransmittedintestinal helminth.There were high rate of platyhelminths infectious behaviourssuch as: eating raw water plant 75.6%, eating raw beef 80.6%, eating raw pork 72.2%, eating raw fish 11.8%, bare foot 34.2%. Conclusions: The result of our study showed that the higher rate of foodborne cestode and trematode than soiltransmittedhelminth correspond tothe hygenic life condition, the knowledge of the diseases and risk behavior of intestinal parasites infection. Key words: Helminth, cestode, trematode

STUDY ON THE RELATIONSHIP BETWEEN PARASITIC INFECTION AND KNOWLEDGE, HYGIENIC PRACTICAL MEASURES OF PARASITIC INFECTIOUS PREVENTION IN VINH THAI COMMUNITY

2017 ◽  
pp. 119-124
Author(s):  
Keyword(s):  
Health Education ◽  
Risk Behaviors ◽  
Ascaris Lumbricoides ◽  
Intestinal Parasite ◽  
Parasitic Infection ◽  
Parasite Infection ◽  
Intestinal Parasite Infection ◽  
Before And After ◽  
Parasite Infections ◽  
The Relationship

Introduction: Intestinal parasite infections werecommonintropical country such as Vietnam. Having good knowledge of parasitic infectious prevention and changing risk behaviors can decrease the infection rate. Objective: To evaluate the parasitic infectious rate in Vinh Thai community before and after being health education and the changing of knowledge of parasitic infectious prevention and risk behaviors. Materials and methods: 60 households in Vinh Thai commune were interviewed their knowledge of parasitic infectious prevention and examined intestinal parasite infection by Kato technique and then trained the knowledge of parasitic infectious prevention. The interview and examination parasite infectiousrate were carried out after 6 months to evaluating their knowledge. Result: Before health education, the rate of intestinal parasite infection was 17.4% with the prevalence of Ascaris lumbricoides, hookworm, whipworm, pinworm, small fluke worm and co-infection with A. lumbricoides - whipworm, hookworm-whipworm were 0.1%; 8.0%; 5.8%; 0.6%; 0.3%; 1.2% and 3.0% respectively. Six months later the rate of intestinal parasite infection was decreased in 12.6% even though not statistical significantly. However, there were no case of small fluke worm and co-infection with hookworm-whipworm. Receiving health education, their knowledge of parasitic infectious prevention was higher significantly but their risk behaviors were not changed so much. Conclusion: Health education can change the rate of parasite infection with higher knowledge of parasitic infectious prevention but it was necessary continuous study to change the risk behaviors. Key words: intestinal parasite, health education

Interest of the XN-10® Analyzer to Screen for Myelodysplastic Syndromes on Complete Blood Count (CBC) Especially with Hemoglobin Levels and Neut-WX

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 5518-5518
Author(s):  
Robin Boutault ◽  
Sebastien Tremblais ◽  
Mathilde De Oliveira Lopes ◽  
Pierre Peterlin ◽  
Yannick Le Bris ◽  
...  
Keyword(s):  
Myelodysplastic Syndromes ◽  
Blood Count ◽  
Complete Blood Count ◽  
Conflicts Of Interest ◽  
Normal Karyotype ◽  
University Hospital ◽  
Multilineage Dysplasia ◽  
End Point ◽  
Group 2 ◽  
A Prospective Study

Abstract A prospective study was performed over one year at Nantes University Hospital in France, in order to investigate whether suspected myelodysplastic syndromes (MDS) could be detected on a complete blood count (CBC), the most rapid laboratory investigation. Indeed, the recently developed XN-10® (Sysmex, Kobe, Japan), provides novel CBC parameters witch could be useful to discriminate such patients from normal samples or from cytopenia of other etiology. Seventy-nine patients were enrolled in the study, for whom a diagnosis of MDS was concluded based on CBC, bone marrow smears examination and karyotype. All patients were free of treatment, including transfusions, at inclusion. They were 40 men and 39 women with a median age of 77,9 years (range 36,4-92,4). CBC were performed on a Sysmex analyzer XN-10®, including investigation of reticulocytes and fluorimetric analysis of platelets. For comparison with normal values, results from 776 healthy samples, for which CBC were performed on the same analyzer and generated no flag, were used. All had parameters within the normal range according to age. The classical parameters of hemoglobin level, Mean Corpuscular Volume (MCV), reticulocytes, platelets and neutrophil counts were recorded. In addition, the extra-parameters, immature reticulocytes fraction (IRF%), platelets by fluorescence (PLT-F) and immature platelets fraction (IPF%), were taken into account. The neutrophils median position on the three axes as well as their dispersion (Neut-WX) were also measured by the analyser. The primary end-point was to discriminate between MDS and healthy patients and the secondary end-point was to distinguish MDS with excess blasts, MDS with multilineage dysplasia and MDS with single lineage dysplasia within the MDS group and by comparison with controls. According to the WHO 2016 classification, 27 patients in the cohort had MDS with excess blasts, 26 MDS with multilineage dysplasia (among whom 7 had ring sideroblasts [RS], group 2), 16 MDS-RS and single lineage dysplasia, 7 MDS with single lineage dysplasia and 3 MDS with isolated del(5q). Forty-four patients had a normal karyotype and 28 displayed anomalies classically reported in MDS, including 5 complex karyotypes. Among the latter, 4 were associated with MDS with excess blasts. Both classical and extra parameters indeed showed significant differences between the subgroups tested. Among the whole group of MDS patients, a number of parameters of all lineages were statistically different from the healthy cohort. The median level of hemoglobin was 9,8 g/dL (range 4,7-14,9), (p<0,0001), the median MCV 104,3 fL (range 75,4-123,9; p<0,0001), reticulocyte counts 44,3x109/L (range 8-165,9; p=0,041) and IRF% 16,7% (range 2,4-50,9; p<0,0001). An hemoglobin value below 11,5 g/dL was strongly suggestive of MDS with a sensitivity of 81% and specificity of 100%. The median platelet count was 164x109/L (range 8-505; p<0,0001) and median IPF% 8,8% (1,2-42; p<0,0001). Among leukocyte parameters, the MDS median neutrophil count was significantly lower at 2,15x109/L (range 0,17-13,67; p<0,001) and the Neut-WX value increased above 350. The latter, by itself, allowed to make a diagnosis of MDS with a sensitivity of 73,1% and a specificity of 96,9%. When considering the three MDS subgroups of MDS with excess blasts, multilineage or single lineage dysplasia, although each of them was significantly different from controls for hemoglobin levels, MCV, IRF% and neutrophil counts (p<0,0001), they could not be discriminated by these parameters. In the subgroup of MDS with single lineage dysplasia, platelet counts were similar to those of controls, yet significantly higher than for MDS with excess blast or with multilineage dysplasia (p=0,004 and p=0,029 respectively). Taken together, this study demonstrates that a simple CBC allows to screen for MDS using thresholds of 11,5 g/dL for hemoglobin and of 350 for Neut-WX. Blood smear examination should be performed in this situation even if the XN-10® analyzer does not raise an alarm, especially in unknown older patients. Disclosures No relevant conflicts of interest to declare.

scholarly journals Malaria and intestinal parasites in pregnant and non-pregnant women: a comparative study at the University Hospital, Kumasi, Ghana

2016 ◽  
Vol 4 (3) ◽  
pp. 31-35
Author(s):  
E. Agboli ◽  
S.C.K. Tay ◽  
C. Obirikorang ◽  
E.Y. Aidoo
Keyword(s):  
Pregnant Women ◽  
Malaria Infection ◽  
Intestinal Parasite ◽  
Intestinal Parasites ◽  
Plasmodium Species ◽  
University Hospital ◽  
Personal Hygiene ◽  
Intestinal Helminth ◽  
African Countries ◽  
The University

In sub-Sahara African countries, both malaria and intestinal helminth infections are endemic and co-infection commonly occurs. It is estimated that over a third of the world’s population, mainly in the tropics and sub-tropics are infected with parasitic helminths and Plasmodium species thus often leading to co-infections. This cross-sectional study was conducted to assess the prevalence of malaria and intestinal parasites in a sample of 760 study participants comprising 380 pregnant women and 380 non-pregnant women attending the University Hospital in Kumasi, Ghana. Blood and stool samples were analyzed for malaria and intestinal parasites using Giemsa staining technique and direct wet mount method respectively. The overall prevalence of malaria infection, intestinal parasite infection and malaria-intestinal parasite co-infection was 73 (9.6%), 43 (5.6%) and 10 (1.3%) respectively. Malaria infection was higher in pregnant women (12.6%) compared to non-pregnant women (6.6%). Non-pregnant women recorded higher intestinal helminth infection (10%) than pregnant women (1.3%). No case of co-infection was recorded among the pregnant women. The study suggests a higher susceptibility to malaria infection when compared to their non-pregnant counterpart with an association between malaria parasite and intestinal helminths in non-pregnant women.Journal of Medical and Biomedical Sciences (2015) 4(3), 31-35Keywords: Ante-natal, infection, personal hygiene, maternal screening, hospital

scholarly journals Occurrence of intestinal parasites amongst persons on highly active antiretroviral drug therapy in Calabar, Cross River State, Nigeria

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Paul C. Inyang-Etoh ◽  
Mfoniso I. Udonkang ◽  
Ade O. Adeboboye
Keyword(s):  
Drug Therapy ◽  
Intestinal Parasite ◽  
Intestinal Parasites ◽  
Parasite Infection ◽  
Cd4 Count ◽  
Intestinal Parasite Infection ◽  
Highly Active ◽  
Significant Difference ◽  
Parasite Infections ◽  
Stool Samples

Opportunistic and intestinal parasite infections are common health problem among HIV/AIDS patients. Early detection and treatment of these parasites are important to improve the quality of life of this category of patients. The occurrence of intestinal parasites among 400 patients on highly active anti-retroviral drug therapy (HAART) aged 11-60 years was investigated. Standard parasitological techniques like direct microscopy, formol ether concentration and modified Ziehl- Neelsen staining techniques were used to analyze the stool samples. Intestinal parasite infections were positive in 116 (29%) of the subjects on HAART while control subjects had 12 (12%) and the difference was statistically significant (P&lt;0.05). Subjects in the age group 21-30 years had the highest infection rate 54 (35.1%). There was no statistically significant difference in infection according to age (P&gt;0.05). Females 76 (32.5%) had a higher prevalence rate than males 40 (24.1%). But there was no statistically significant difference in infection according to gender (P&lt;0.05). Patients with CD4 count of less than 200 cells/mm3 were observed to be more infected than those with CD4 count of more than 200 cells/mm3. There was a strong positive correlation (r=0.94) between CD4 count and the occurrence of intestinal parasite infection. Protozoan parasites 84 (21.0%) accounted for a higher prevalence rate than helminthic parasites 32 (8.0%). These findings has revealed a high prevalence of intestinal parasite infection among patients on HAART thus the routine screening of stool samples from these category of patients for intestinal parasites is advocated for effective management of the disease.

scholarly journals A Retrospective Study of Intestinal Parasite among Patients in the Ho Teaching Hospital, Ghana

2019 ◽  
pp. 1-8
Author(s):  
Maxwell Afranie Appiah ◽  
Ebenezer Enam Adzaklo ◽  
Eric Agboli
Keyword(s):  
Retrospective Study ◽  
Teaching Hospital ◽  
Intestinal Parasite ◽  
Intestinal Parasites ◽  
Age Groups ◽  
Parasite Infection ◽  
Stool Examination ◽  
Parasitic Infections ◽  
Intestinal Parasite Infection ◽  
Parasite Infections

Aim: To assess the prevalence of intestinal parasite infections among patients who visit the Ho Teaching Hospital for stool examination from 2012 to 2016. Study Design: Retrospective study. Place and Duration of Study: Ho Teaching Hospital, August 2017 to January 2018. Methodology: The hospital’s laboratory records were reviewed. Patients’ data were recorded using a well-designed data collection tool. Data was analyzed with Statistical Package for Social Science (SPSS) version 20.0. Results:  A total of 7045 patients visited the Ho Teaching Hospital laboratory for routine stool examination within the five-year period. From the 7045 patients, 703 of them were infected with at least one of the intestinal parasites. The overall prevalence of intestinal parasite infection for the five-year period was 10.0%. Intestinal flagellates (90.0%) were the most predominant intestinal parasites, and Entamoeba histolytica recorded 5.7%. Hookworm (0.9%) was the most prevailing soil-transmitted helminth. Ascaris lumbricoides (0.1%) and Schistosoma mansoni (0.1%) were the least recorded parasites. Highest infection was among patients within age group 20 to 29 years. However, age groups below 10 years recorded low infection. This study showed that age was a risk factor for acquiring intestinal parasite infection (P≤0.001). Conclusion: Intestinal parasitic infections were recorded among patients who visited the Ho Teaching Hospital. However, most of the patients were infected with intestinal flagellates. Various stakeholders should provide advance techniques in laboratory investigation of stool samples to enhance accurate diagnosis. Sensitization of the public about the dangers of intestinal parasites should also be undertaken by the stakeholders.

scholarly journals Impact of using a local protocol in preoperative testing: blind randomized clinical trial.

2017 ◽  
Vol 44 (1) ◽  
pp. 54-63 ◽  
Author(s):  
MÔNICA LOUREIRO SANTOS ◽  
ANTÔNIO CARLOS IGLESIAS
Keyword(s):  
Clinical Trial ◽  
Blood Count ◽  
Complete Blood Count ◽  
Perioperative Complications ◽  
Anesthetic Management ◽  
University Hospital ◽  
Clinical Indication ◽  
Significant Difference ◽  
The Impact ◽  
Local Protocol

ABSTRACT Objective: to evaluate the impact of the use of a local protocol of preoperative test requests in reducing the number of exams requested and in the occurrence of changes in surgical anesthetic management and perioperative complications. Methods: we conducted a randomized, blinded clinical trial at the Gaffrée and Guinle University Hospital with 405 patients candidates for elective surgery randomly divided into two groups, according to the practice of requesting preoperative exams: a group with non-selectively requested exams and a protocol group with exams requested according to the study protocol. Studied exams: complete blood count, coagulogram, glycemia, electrolytes, urea and creatinine, ECG and chest X-ray. Primary outcomes: changes in surgical anesthetic management caused by abnormal exams, reduction of the number of exams requested after the use of the protocol and perioperative complications. Results: there was a significant difference (p<0.001) in the number of exams with altered results between the two groups (14.9% vs. 29.1%) and a reduction of 57.3% in the number of exams requested between the two groups (p<0.001), which was more pronounced in patients of lower age groups, ASA I, without associated diseases and submitted to smaller procedures. There was no significant difference in the frequency of conduct changes motivated by the results of exams or complications between the two groups. In the multivariate analysis, complete blood count and coagulogram were the only exams capable of modifying the anesthetic-surgical management. Conclusion: the proposed protocol was effective in eliminating a significant number of complementary exams without clinical indication, without an increase in perioperative morbidity and mortality.

scholarly journals PREVALENCE OF INTESTINAL HELMINTHIASIS IN CHILDREN AT NORTH KEPUTRAN SURABAYA AT 2017

2018 ◽  
Vol 1 (3) ◽  
pp. 117 ◽  
Author(s):  
Hana Naili Prasetyo ◽  
Heru Prasetyo
Keyword(s):  
Intestinal Parasite ◽  
Parasite Infection ◽  
Stool Examination ◽  
Intestinal Helminth ◽  
Adhesive Tape ◽  
Gender And Age ◽  
Anal Swab ◽  
Intestinal Worms ◽  
Male Patients ◽  
The Village

Background: Parasite infection is still an endemic disease that can be found in any place in Indonesia that can cause problems in public health, especially for children. Intestinal helminthiasis can interfere with children’s growth and development which will affect their quality of life. Purpose: The purpose of this research is to find out the prevalence of intestinal helminthiasis among children in Pasar Kampung Keputran Surabaya. It is located at the riverbank and the majority people are immigrants that lead to population density and slum. Methods: This descriptive observational study anal swab specimens with Scotch adhesive tape swab method and fecal specimen were examined microscopically at the Laboratory of Parasitology, Faculty of Medicine, Airlangga University. Result: according to the finding of the anal swab and stool examination: 36 % specimens were infected by intestinal helminth as follows: Enterobiasis 28 %, Ascariasis 4% and Hymenolepiasis 4% Intestinal parasite sufferers 62,5% male and 37,5% women with vulnerable age of a patient 6-11 year. Conclusion: It can be concluded that the prevalence of intestinal helminthiasis in children in the village of Pasar Keputran Utara Surabaya is quite high, ie 36% infected intestinal worms. Gender and age are also influential. Proven male patients are higher than women. Densely populated areas, poor environmental and sanitation, and the intensity and intensity of child contact with the outdoors are responsible for high rates of intestinal parasite infection in the area.

scholarly journals Two Helminthic Cases of Human Mummy Remains from Joseon-Period Graves in Korea

2021 ◽  
Vol 59 (2) ◽  
pp. 149-152
Author(s):  
Chang Seok Oh ◽  
Hyejin Lee ◽  
Jieun Kim ◽  
Jong Ha Hong ◽  
Soon Chul Cha ◽  
...  
Keyword(s):  
Clonorchis Sinensis ◽  
Human Remains ◽  
Parasite Infection ◽  
Trichuris Trichiura ◽  
Infection Rates ◽  
Modern Period ◽  
Joseon Dynasty ◽  
The Republic ◽  
Human Mummy ◽  
Existing Data

Our previous research on coprolite specimens from the mummies of Joseon Dynasty (1392-1910 CE) has revealed various species of parasite eggs. Herein, we added 2 new helminthic cases of human remains from Joseon-period graves in the Republic of Korea (Korea). The organic materials precipitated on the hip bones of 2 half-mummied cases (Goryeong and Gwangmyeong cases) were collected, rehydrated, and examined by a microscope. In the sample from Goryeong-gun (gun=County), ova of <i>Trichuris trichiura, Clonorchis sinensis</i>, and <i>Metagonimus</i> spp. were detected, and eggs of <i>T. trichiura</i> and <i>A. lumbricoides</i> were found from the sample of Gwangmyeong-si (si=City). By adding this outcome to the existing data pool, we confirm our previous estimates of Joseon-period parasite infection rates. The overall rates of <i>A. lumbricoides, T. trichiura</i>, and <i>C. sinensis</i> decreased dramatically from Joseon to the modern period. In Goryeong mummy specimen, we also found <i>Metagonimus</i> spp. eggs that has rarely been detected in archaeological samples so far.

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