STUDY ON THE VALUE OF C-REACTIVE PROTEIN IN CHILDREN WITH ACUTE GLOMERULONEPHRITIS

2011 ◽  
pp. 99-105
Author(s):  
Viet Hieu Ho
Keyword(s):  
Sedimentation Rate ◽  
White Blood Cells ◽  
Descriptive Study ◽  
Average Concentration ◽  
Acute Glomerulonephritis ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Blood Sedimentation ◽  
Blood Sedimentation Rate ◽  
Study Results

Background: We had assessed the value of C-reactive protein (CRP) in children with Glomerulonephritis Acute (GNA). Study on the interrelation between CRP and the signs of clinic, paraclinic. Population and Methods: Patients : 35 patients with GNA age 1 – 15 years old in Pediatric Department of Hue Central Hospital from 4 / 2008 to 4 / 2009. Methods: Prospective, descriptive study. Results: No fever (74.30%); White blood cells>7000/mm3 (60%); Blood sedimentation rate>10mm (74.30%); ASLO>200UI/L (37.14%); normal CRP≤ 8mg/l (60%); CRP>8mg/l - 300mg/l (40%). CRP is no related to the fever sign (r = 0,162; p>0,05). CRP is positive tightly correlated with White blood (r = 0.680; p<0.05), with ASLO (r = 0,660; p<0,05) and CRP is positive moderate correlated with Blood sedimentation rate (r = 0,392; p<0,05). Conclusions: The CRP increased in GNA of children is 40%. Before treating, the average concentration of CRP is 12,88 ± 30,93 mg/l . After treating, the concentration of CRP is≤8mg/l (97.10%). Key words: CRP; Glomerulonephritis Acute

C-REACTIVE PROTEIN IN THE SERUM IN NEPHROSIS AND ACUTE GLOMERULONEPHRITIS

PEDIATRICS ◽  
1960 ◽  
Vol 25 (1) ◽  
pp. 106-111
Author(s):  
Aree Valyasevi ◽  
Joseph M. Sloan ◽  
Lewis A. Barness
Keyword(s):  
Nephrotic Syndrome ◽  
Hormone Therapy ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Positive Test ◽  
Acute Glomerulonephritis ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

C-reactive protein in the serum and the erythrocyte sedimentation rate were followed serially in 13 patients with acute nephritis and in 9 patients with the nephrotic syndrome. Although a positive C-reactive protein test was always associated with evidence of infection, obvious infection in a few instances was not accompanied by a positive test. Determination of C-reactive protein is valuable in determining the presence of infection in patients with acute nephritis and the nephrotic syndrome, especially in the latter where hormone therapy may mask many signs of infection.

The correlation between the concentration of faecal calprotectin and markers of inflammation in children with gastrointestinal disorders

2017 ◽  
Vol 53 (2) ◽  
pp. 91-96
Author(s):  
Katarzyna Lewandowska ◽  
Olga Ciepiela
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Intestinal Inflammation ◽  
White Blood Cells ◽  
Intestinal Lumen ◽  
C Reactive Protein ◽  
Faecal Calprotectin ◽  
Reactive Protein ◽  
Markers Of Inflammation ◽  
Erythrocyte Sedimentation

Introduction: Calprotectin is an acute phase protein that occurs in large amounts in the granules and cytosolic fluid of neutrophils, and in smaller amounts in monocytes and macrophages. In bowel inflammation, increased neutrophil migration from the circulation to the intestinal lumen is observed as a consequence of mucosal damage. This leads to the release of a significant amount of calprotectin by activated leukocytes in intestine, thereby increasing its concentration in the faeces. This allows the non-invasive assessment of intestinal inflammation. Other markers useful in patients with bowel inflammation are erythrocyte sedimentation rate and C-reactive protein. Aim: The aim of the study was to evaluate the correlation between the concentration of faecal calprotectin (FC) and other markers of inflammation, such as C-reactive protein (CRP) and ferritin in serum, erythrocyte sedimentation rate (ESR) and white blood cells (WBC) count and in children with Crohn’s disease and ulcerative colitis. Material and methods: This study is based on a retrospective analysis of laboratory results of 370 children suspected of inflammatory bowel disease (IBD). Pearson’s coefficient was used to assess the correlation between the parameters. Results: There was a positive correlation between concentration of FC and parameters such as CRP (r=0.16; p=0.0345), ESR (r=0.38; p<0.0001) and WBC (r=0.24; p=0.0008) in children with IBD. There was also a negative correlation between concentration of FC and ferritin (r=-0.24; p=0.0089) in children with IBD. Conclusion: In this study, ESR turned out to be more adequate than CRP and WBC in detecting inflammation in patients with IBD.

Diagnostic value of procalcitonin, erythrocyte sedimentation rate (ESR), quantitative C-reactive protein (CRP) and clinical findings associated with osteomyelitis in patients with diabetic foot

2021 ◽  
pp. 1-7
Author(s):  
Zahra Soleimani ◽  
Fatemeh Amighi ◽  
Zarichehr Vakili ◽  
Mansooreh Momen-Heravi ◽  
Seyyed Alireza Moravveji
Keyword(s):  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Roc Curve ◽  
Diabetic Foot ◽  
Diagnostic Value ◽  
Clinical Findings ◽  
Diabetic Patients ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation

BACKGROUND: The diagnosis of osteomyelitis is a key step of diabetic foot management. Procalcitonin (PCT) is a novel infection marker. This study aimed to investigate the diagnostic value of procalcitonin and other conventional infection markers and clinical findings in diagnosis of osteomyelitis in diabetic foot patients. METHODS AND MATERIALS: This diagnostic value study was carried out on ninety patients with diabetic infected foot ulcers admitted in Kashan Beheshti Hospital, 2016. After obtaining consent, 10 cc blood sample was taken for measuring serum PCT, CBC, ESR, CRP and FBS. Clinical characteristics of the wounds were noted. Magnetic resonance imaging of the foot was performed in all patients to diagnose osteomyelitis. All statistical analyses were done with the use of SPSS-16. RESULTS: PCT levels were 0.13 ± 0.02 ng/mili patients with osteomyelitis (n= 45) and 0.04 ± 0.02 ng/ml in patients without osteomyelitis (n= 45). PCT, Erythrocyte sedimentation rate and C-reactive protein was found significantly higher in patients with osteomyelitis (p< 0.001). The ROC curve was calculated for PCT. The area under the ROC curve for infection identification was 1 (p< 0.001). The best cut-off value for PCT was 0.085 ng/ml. Sensitivity, specificity, and positive and negative predictive values were 100%, 97.8%,97.8% and 100%, respectively. CONCLUSION: In this group of patients, PCT was useful to discriminate patients with bone infection. Also, Erythrocyte sedimentation rate and C-reactive protein can be used as a marker of osteomyelitis in diabetic patients.

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