Device embedding assembly technology

2019 ◽  
Keyword(s):  
Assembly Technology

scholarly journals Construction of Chitosan/Alginate Nano-Drug Delivery System for Improving Dextran Sodium Sulfate-Induced Colitis in Mice

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1884
Author(s):  
Mengfei Jin ◽  
Shangyong Li ◽  
Yanhong Wu ◽  
Dandan Li ◽  
Yantao Han
Keyword(s):  
Self Assembly ◽  
Average Diameter ◽  
Mucosal Healing ◽  
Plga Nanoparticles ◽  
Narrow Particle Size Distribution ◽  
Layer By Layer ◽  
Systemic Side Effects ◽  
Assembly Technology ◽  
The Fourier Transform ◽  
Polyelectrolyte Film

(1) Background: In the treatment of ulcerative colitis (UC), accurate delivery and release of anti-inflammatory drugs to the site of inflammation can reduce systemic side effects. (2) Methods: We took advantage of this goal to prepare resveratrol-loaded PLGA nanoparticles (RES-PCAC-NPs) by emulsification solvent volatilization. After layer-by-layer self-assembly technology, we deposited chitosan and alginate to form a three-layer polyelectrolyte film. (3) Results: It can transport nanoparticles through the gastric environment to target inflammation sites and slowly release drugs at a specific pH. The resulting RES-PCAC-NPs have an ideal average diameter (~255 nm), a narrow particle size distribution and a positively charged surface charge (~13.5 mV). The Fourier transform infrared spectroscopy showed that resveratrol was successfully encapsulated into PCAC nanoparticles, and the encapsulation efficiency reached 87.26%. In addition, fluorescence imaging showed that RES-PCAC-NPs with positive charges on the surface can effectively target and accumulate in the inflammation site while continuing to penetrate downward to promote mucosal healing. Importantly, oral RES-PCAC-NPs treatment in DSS-induced mice was superior to other results in significantly improved inflammatory markers of UC. (4) Conclusions: Our results strongly prove that RES-PCAC-NPs can target the inflamed colon for maximum efficacy, and this oral pharmaceutical formulation can represent a promising formulation in the treatment of UC.

Human skill integrated motion planning of assembly manipulation for 6R industrial robot

2019 ◽  
Vol 46 (1) ◽  
pp. 171-180
Author(s):  
Yi Liu ◽  
Ming Cong ◽  
Hang Dong ◽  
Dong Liu
Keyword(s):  
Deep Learning ◽  
Motion Planning ◽  
Industrial Robot ◽  
Robotic Assembly ◽  
3D Vision ◽  
Content Type ◽  
Human Skill ◽  
Depth Images ◽  
Positioning Method ◽  
Assembly Technology

Purpose The purpose of this paper is to propose a new method based on three-dimensional (3D) vision technologies and human skill integrated deep learning to solve assembly positioning task such as peg-in-hole. Design/methodology/approach Hybrid camera configuration was used to provide the global and local views. Eye-in-hand mode guided the peg to be in contact with the hole plate using 3D vision in global view. When the peg was in contact with the workpiece surface, eye-to-hand mode provided the local view to accomplish peg-hole positioning based on trained CNN. Findings The results of assembly positioning experiments proved that the proposed method successfully distinguished the target hole from the other same size holes according to the CNN. The robot planned the motion according to the depth images and human skill guide line. The final positioning precision was good enough for the robot to carry out force controlled assembly. Practical implications The developed framework can have an important impact on robotic assembly positioning process, which combine with the existing force-guidance assembly technology as to build a whole set of autonomous assembly technology. Originality/value This paper proposed a new approach to the robotic assembly positioning based on 3D visual technologies and human skill integrated deep learning. Dual cameras swapping mode was used to provide visual feedback for the entire assembly motion planning process. The proposed workpiece positioning method provided an effective disturbance rejection, autonomous motion planning and increased overall performance with depth images feedback. The proposed peg-hole positioning method with human skill integrated provided the capability of target perceptual aliasing avoiding and successive motion decision for the robotic assembly manipulation.

Continuing Application of Torque-Position Assembly Technology for API Connections

2011 ◽  
Vol 26 (03) ◽  
pp. 408-411
Author(s):  
James P. Powers ◽  
Michael S. Chelf
Keyword(s):  
Assembly Technology

Structure Design and Analysis for the Spacecraft On-Orbit Replacement Unit (ORU)

2013 ◽  
Vol 437 ◽  
pp. 449-453 ◽  
Author(s):  
Xi Zhai ◽  
Xin Hong Li ◽  
Si Yin Zhou
Keyword(s):  
Complex Structure ◽  
Structure Design ◽  
Module Structure ◽  
Assembly Technology ◽  
Universal Structure ◽  
Module Structures

By using on-orbit replacement and assembly technology, some fresh ideas and methods for the design, produce and application of spacecraft were put forward. Universal structure is one of the most basic requirements of On-Orbit replacement, assembly. Module structure must obey the rules of the Operationally Responsive Space (ORS). According to the degree of spacecraft module division, two module structures were proposed, and the complex structure was analyzed to verify the correctness of it.

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