Cosmetics - Analytical methods - LC/UV method for the identification and quantitative determination in cosmetic products of the 22 organic UV filters in use in the EU

2018 ◽  
Keyword(s):  
Quantitative Determination ◽  
Analytical Methods ◽  
Uv Filters ◽  
Cosmetic Products ◽  
Organic Uv Filters ◽  
The Eu

scholarly journals An Overview of the Analytical Methods for the Determination of Organic Ultraviolet Filters in Cosmetic Products and Human Samples

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4780
Author(s):  
Izabela Narloch ◽  
Grażyna Wejnerowska
Keyword(s):  
Analytical Methods ◽  
Limit Of Detection ◽  
Biological Fluids ◽  
Analytical Techniques ◽  
Detection Accuracy ◽  
Uv Filters ◽  
Cosmetic Products ◽  
Monitoring Protocols ◽  
Accuracy And Repeatability

UV filters are a group of compounds commonly used in different cosmetic products to absorb UV radiation. They are classified into a variety of chemical groups, such as benzophenones, salicylates, benzotriazoles, cinnamates, p-aminobenzoates, triazines, camphor derivatives, etc. Different tests have shown that some of these chemicals are absorbed through the skin and metabolised or bioaccumulated. These processes can cause negative health effects, including mutagenic and cancerogenic ones. Due to the absence of official monitoring protocols, there is an increased number of analytical methods that enable the determination of those compounds in cosmetic samples to ensure user safety, as well as in biological fluids and tissues samples, to obtain more information regarding their behaviour in the human body. This review aimed to show and discuss the published studies concerning analytical methods for the determination of organic UV filters in cosmetic and biological samples. It focused on sample preparation, analytical techniques, and analytical performance (limit of detection, accuracy, and repeatability).

scholarly journals Advances in analytical methods and occurrence of organic UV-filters in the environment — A review

2015 ◽  
Vol 526 ◽  
pp. 278-311 ◽  
Author(s):  
Sara Ramos ◽  
Vera Homem ◽  
Arminda Alves ◽  
Lúcia Santos
Keyword(s):  
Analytical Methods ◽  
Uv Filters ◽  
Organic Uv Filters

scholarly journals A novel and widely accessible HPLC method for determination content of homosalate in sunscreen products on the market

2017 ◽  
Vol 7 (3) ◽  
pp. 196-204
Author(s):  
Belma Imamovic ◽  
Zinajda Bešić ◽  
Ervina Bečić
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
Analytical Method ◽  
Harmful Effect ◽  
Hplc Method ◽  
Uv Filters ◽  
Cosmetic Products ◽  
Sunscreen Products ◽  
Sensitive Method ◽  
Organic Uv Filters

Introduction: Considering that the research has shown that homosalate act as endocrine-active substance, it is very important to develop quick and sensitive method for tracking its concentrations in sunscreen products. The aim of this paper is to develop and validate the method for determining homosalate in sunscreen preparations and controlling the content of the products found on the market of Bosnia and Herzegovina. Methods: A high pressure liquid chromatography (HPLC) method for determination homosalate in sunscreen products has been developed and validated. Samples of six different manufacturers have been analyzed. HPLC method is method of choice for this type of investigation. Results: According to the calibration curve it has been found that the proposed analytical method in a given range of concentration is linear and that the correlation coefficient is R2=0.9998. Accuracy of the method is in range 94.26% -121.53%.The results have shown that the homosalate concentration in the tested samples did not exceed the maximally permissible concentration (10%). In the sample AV50 homosalate was not declared as an active ingredient, but it was identified and quantified at a concentration of 0.143%. Conclusion: Results of investigation of cosmetic products that are widely present on the market show the need of developing a sufficiently sensitive, easily accessible, analytical method for controlling the content of organic UV filters since the exceeding of the maximally permissible concentration can have a harmful effect on people who use these kinds of products. The results show that developed method meets conditions and is suitable for wide application.

scholarly journals Synthesis of Deuterated Surrogate Standards for the Analysis of Legally Regulated Substances in Cosmetics

2020 ◽  
Author(s):  
Fariña Beatriz ◽  
Carlos González ◽  
Manuel Lolo ◽  
F. Javier Sardina
Keyword(s):  
European Union ◽  
Continuous Improvement ◽  
Analytical Methods ◽  
Raw Materials ◽  
Synthetic Methods ◽  
The European Union ◽  
Cosmetic Products ◽  
Musk Xylene ◽  
Harmful Substances ◽  
Musk Ambrette

<p>The presence of harmful substances in cosmetic products is regulated in most countries. In the European Union the Regulation (EC) No. 1223/2009 lays down the requirements for the marketing of cosmetic products. Among others, important families of compounds restricted in the Regulation are musks, allergenic fragrances and phthalates. To ensure product safety, improved analytical methods capable of reliably and reproducibly detecting the presence of traces of prohibited and/or restricted ingredients in raw materials and finished products are required. </p> <p>For the continuous improvement of the reliability of the analytical methods developed to check the compliance of cosmetic products with the Regulation, the use of appropriate surrogate standards or contaminants (substances that are added to the samples to be analyzed to establish the recovery and the reproducibility of the quantification of the analytes) are of utmost importance. One of the best kinds of surrogate standards are isotopically labeled analogs of the analytes of interest. In this work, several synthetic methods have been developed to prepare isotopically labeled analogs of atranol, chloroatranol, di-n-octylphthalate, musk xylene, and musk ambrette, which are restricted substances in cosmetic articles.</p>

Sign in / Sign up

Export Citation Format

Share Document