Cosmetics. Analytical methods. HPLC/UV method for the identification and assay of hydroquinone, ethers of hydroquinone and corticosteroids in skin whitening cosmetic products

2017 ◽  
Keyword(s):  
Analytical Methods ◽  
Cosmetic Products ◽  
Skin Whitening

scholarly journals Synthesis of Deuterated Surrogate Standards for the Analysis of Legally Regulated Substances in Cosmetics

2020 ◽  
Author(s):  
Fariña Beatriz ◽  
Carlos González ◽  
Manuel Lolo ◽  
F. Javier Sardina
Keyword(s):  
European Union ◽  
Continuous Improvement ◽  
Analytical Methods ◽  
Raw Materials ◽  
Synthetic Methods ◽  
The European Union ◽  
Cosmetic Products ◽  
Musk Xylene ◽  
Harmful Substances ◽  
Musk Ambrette

<p>The presence of harmful substances in cosmetic products is regulated in most countries. In the European Union the Regulation (EC) No. 1223/2009 lays down the requirements for the marketing of cosmetic products. Among others, important families of compounds restricted in the Regulation are musks, allergenic fragrances and phthalates. To ensure product safety, improved analytical methods capable of reliably and reproducibly detecting the presence of traces of prohibited and/or restricted ingredients in raw materials and finished products are required. </p> <p>For the continuous improvement of the reliability of the analytical methods developed to check the compliance of cosmetic products with the Regulation, the use of appropriate surrogate standards or contaminants (substances that are added to the samples to be analyzed to establish the recovery and the reproducibility of the quantification of the analytes) are of utmost importance. One of the best kinds of surrogate standards are isotopically labeled analogs of the analytes of interest. In this work, several synthetic methods have been developed to prepare isotopically labeled analogs of atranol, chloroatranol, di-n-octylphthalate, musk xylene, and musk ambrette, which are restricted substances in cosmetic articles.</p>

scholarly journals An Overview of the Analytical Methods for the Determination of Organic Ultraviolet Filters in Cosmetic Products and Human Samples

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4780
Author(s):  
Izabela Narloch ◽  
Grażyna Wejnerowska
Keyword(s):  
Analytical Methods ◽  
Limit Of Detection ◽  
Biological Fluids ◽  
Analytical Techniques ◽  
Detection Accuracy ◽  
Uv Filters ◽  
Cosmetic Products ◽  
Monitoring Protocols ◽  
Accuracy And Repeatability

UV filters are a group of compounds commonly used in different cosmetic products to absorb UV radiation. They are classified into a variety of chemical groups, such as benzophenones, salicylates, benzotriazoles, cinnamates, p-aminobenzoates, triazines, camphor derivatives, etc. Different tests have shown that some of these chemicals are absorbed through the skin and metabolised or bioaccumulated. These processes can cause negative health effects, including mutagenic and cancerogenic ones. Due to the absence of official monitoring protocols, there is an increased number of analytical methods that enable the determination of those compounds in cosmetic samples to ensure user safety, as well as in biological fluids and tissues samples, to obtain more information regarding their behaviour in the human body. This review aimed to show and discuss the published studies concerning analytical methods for the determination of organic UV filters in cosmetic and biological samples. It focused on sample preparation, analytical techniques, and analytical performance (limit of detection, accuracy, and repeatability).

scholarly journals Plants and Natural Products for the Treatment of Skin Hyperpigmentation – A Review

Planta Medica ◽  
2018 ◽  
Vol 84 (14) ◽  
pp. 988-1006 ◽  
Author(s):  
Mayuree Kanlayavattanakul ◽  
Nattaya Lourith
Keyword(s):  
Natural Products ◽  
Biological Activities ◽  
Cosmetic Products ◽  
Efficient Treatment ◽  
Skin Whitening ◽  
Natural Extracts ◽  
Skin Hyperpigmentation ◽  
The Status

AbstractSkin hyperpigmentation is caused by several factors that upregulate melanogenesis. Plants and natural products with skin-whitening effects are gaining interest among consumers and researchers because they are perceived to be milder, safer, and healthier than synthetic alternatives. This review extensively summarizes the status of plants and natural products currently used in skin-whitening cosmetics as well as potential candidates for future use, because the scope of natural choices for efficient treatment of skin hyperpigmentation is rapidly widening. Biological activities of plants and natural extracts are therefore available for cosmetic formulators and dermatologists interested in naturally derived ingredients for skin hyperpigmentation treatment and in accordance with the consumersʼ preferences and expectations upon natural cosmetic products.

scholarly journals Synthesis of Deuterated Surrogate Standards for the Analysis of Legally Regulated Substances in Cosmetics

2020 ◽  
Author(s):  
Fariña Beatriz ◽  
Carlos González ◽  
Manuel Lolo ◽  
F. Javier Sardina
Keyword(s):  
European Union ◽  
Continuous Improvement ◽  
Analytical Methods ◽  
Raw Materials ◽  
Synthetic Methods ◽  
The European Union ◽  
Cosmetic Products ◽  
Musk Xylene ◽  
Harmful Substances ◽  
Musk Ambrette

<p>The presence of harmful substances in cosmetic products is regulated in most countries. In the European Union the Regulation (EC) No. 1223/2009 lays down the requirements for the marketing of cosmetic products. Among others, important families of compounds restricted in the Regulation are musks, allergenic fragrances and phthalates. To ensure product safety, improved analytical methods capable of reliably and reproducibly detecting the presence of traces of prohibited and/or restricted ingredients in raw materials and finished products are required. </p> <p>For the continuous improvement of the reliability of the analytical methods developed to check the compliance of cosmetic products with the Regulation, the use of appropriate surrogate standards or contaminants (substances that are added to the samples to be analyzed to establish the recovery and the reproducibility of the quantification of the analytes) are of utmost importance. One of the best kinds of surrogate standards are isotopically labeled analogs of the analytes of interest. In this work, several synthetic methods have been developed to prepare isotopically labeled analogs of atranol, chloroatranol, di-n-octylphthalate, musk xylene, and musk ambrette, which are restricted substances in cosmetic articles.</p>

scholarly journals Bahaya Kosmetika Pemutih yang Mengandung Merkuri dan Hidroquinon serta Pelatihan Pengecekan Registrasi Kosmetika di Rumah Sakit Gunung Jati Cirebon

2018 ◽  
Vol 1 (1) ◽  
pp. 8
Author(s):  
Sulistiorini Indriaty ◽  
Nur Rahmi Hidayati ◽  
Arsyad Bachtiar
Keyword(s):  
Outpatient Clinic ◽  
Skin Tone ◽  
Cosmetic Products ◽  
Active Ingredients ◽  
Negative Effects ◽  
Waiting Room ◽  
Skin Whitening ◽  
Knowledge And Skills ◽  
Registration Number ◽  
Active Substances

Skin whitening products are one of the cosmetic products that contain active ingredients that can suppress or inhibit the formation of melanin or eliminate melanin that has been formed so as to give a whiter skin tone. Limitations of knowledge about various whitening cosmetic products make people do not know the negative effects that arise if not careful. Mercury and hydroquinone are some active substances that are often misused by illegal cosmetics manufacturers. But in fact the abuse of mercury and hydroquinone is still common in whitening products. This activity was carried out with the aim of providing knowledge and skills to the community, especially waiting room patients in the outpatient clinic at Gunung Jati Cirebon Hospital in terms of checking the registration number for cosmetics. This activity was carried out with counseling methods and question and answer about the material hazards of using whitening cosmetics containing mercury and Hydroquinone is followed by training in checking the registration number for cosmetics using an Android cellphone. From this activity it can be concluded that patients are more aware of the dangers of mercury and hydroquinone and can directly check cosmetic products that are commonly used everyday.

Sign in / Sign up

Export Citation Format

Share Document