Chemicals used for treatment of water intended for human consumption. Calcium magnesium carbonate

2011 ◽  
Keyword(s):  
Magnesium Carbonate ◽  
Human Consumption ◽  
Calcium Magnesium

scholarly journals Onset of acid-neutralizing action of a calcium/magnesium carbonate-based antacid using an artificial stomach model: an in vitro evaluation

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maxim Voropaiev ◽  
Deborah Nock
Keyword(s):  
In Vitro Study ◽  
Magnesium Carbonate ◽  
Human Gastrointestinal Tract ◽  
Pepsin Activity ◽  
Onset Of Action ◽  
Over The Counter ◽  
Calcium Magnesium ◽  
Secondary Objective ◽  
Time Required

Abstract Background Calcium carbonate antacids are potent over-the-counter antacids, made more effective by adding magnesium carbonate (as in Rennie, Bayer). However, published studies on their onset of action are scarce. Therefore, we carried out an in vitro study comparing Rennie and placebo under simulated conditions of the human stomach (artificial stomach model) to reconfirm the onset of action of Rennie. Methods The validated Simulator of the Human Intestinal Microbial Ecosystem apparatus (SHIME, ProDigest, Belgium) was used, comprising five reactors simulating different parts of the human gastrointestinal tract. Both Rennie and placebo were dosed at two tablets per incubation over six independent, 2-h stomach incubations each. Primary objectives: to evaluate the time required to achieve pH 3.0, 3.5, 4.0 and 4.5, as well as the maximum pH reached. Secondary objective: to evaluate pepsin activity over the entire 2-h gastric incubation. Results After addition of Rennie, the gastric medium reached a pH of 3.0 within 40 s. The maximum pH of 5.24 was maintained for almost 10 min. In contrast, the maximum pH with placebo was 1.28 during the entire gastric simulation. Furthermore, Rennie strongly reduced the activity of mucosa-damaging pepsin during the period of increased pH. With placebo, the lower pH resulted in consistently high loads of digested peptides, reflecting the high cumulative and instantaneous pepsin activity. Conclusions New data is a critical component in informed decision making. Our data confirm the high efficacy and fast onset of acid-neutralizing action of Rennie, which begins to work within seconds.

scholarly journals ASSESSMENT OF WATER QUALITY AND POLLUTION LOAD IN TEJASWINI RIVER NEAR THE MALAVETTUVAN TRIBAL SETTLEMENT, CHERUPUZHA PANCHAYATH, KERALA, INDIA

2017 ◽  
Vol 4 (3) ◽  
pp. 71-74
Author(s):  
Sangeeth Thekkan ◽  
Renjini Haridas ◽  
Paulsamy S
Keyword(s):  
Water Quality ◽  
River Water ◽  
Forest Canopy ◽  
Water Quality Assessment ◽  
Primary Sources ◽  
Human Consumption ◽  
Physico Chemical ◽  
Calcium Magnesium ◽  
Domestic Use ◽  
Canopy Water

Rivers are one of the primary sources of water for drinking, irrigation and other domestic purposes.The present study deals with the water quality assessment of Tejaswini river of Cherupuzha Panchayath, Kannur district, Kerala. The water samples collected from five different sites were analyzed for parameters such as temperature, color, pH, BOD, DO, calcium, magnesium and Escherichia coli. The analysis of the physico– chemical and microbiological characters of the river water indicated that the water quality study of site I was affected severely because the study site is very near to the tribal settlements and also the tribes use thisarea mainly for sewage disposal. Study site II, III, IV and V, which are away from the tribal settlement, the river water is not polluted as it is very far away from the tribal settlement and also nearer to forest canopy. Water from study site I which not suitable for drinking and other domestic use. Therefore, source protectionis suggested for the site I water bodies for the benefit of mankind because it is not safe for human consumption.

scholarly journals Amorphous Calcium–Magnesium Carbonate (ACMC) Accelerates Dolomitization at Room Temperature under Abiotic Conditions

2020 ◽  
Vol 20 (3) ◽  
pp. 1434-1441 ◽  
Author(s):  
German Montes-Hernandez ◽  
François Renard ◽  
Anne-Line Auzende ◽  
Nathaniel Findling
Keyword(s):  
Room Temperature ◽  
Magnesium Carbonate ◽  
Abiotic Conditions ◽  
Calcium Magnesium

scholarly journals Effect of an industrial chemical waste on the uptake of cations by green oat

2007 ◽  
Vol 72 (6) ◽  
pp. 629-633 ◽  
Author(s):  
Hortensia Radulescu ◽  
Lidia Taubert ◽  
Sándor Kiss ◽  
Ecaterina Princz ◽  
Éva Stefanovits-Bányai
Keyword(s):  
Avena Sativa ◽  
Magnesium Carbonate ◽  
Antagonistic Effect ◽  
Chemical Waste ◽  
Copper Compounds ◽  
Industrial Manufacture ◽  
Calcium Magnesium ◽  
Calcium And Magnesium ◽  
Iron And Manganese ◽  
Manganese Chromium

Calcium carbonate, obtained as a waste in the industrial manufacture of magnesium carbonate and magnesium oxide from dolomites, can be applied in agriculture. The appreciable amounts of calcium and magnesium in this waste, together with impurities such as iron, zinc, manganese, chromium and copper compounds can be useful in soil amendment and plant nutrition. This paper presents preliminary results of the testing of several waste doses on soil, pursuing their effect on the uptake of cations by green oat (Avena sativa L.). The obtained results show an increase in the amount of calcium, magnesium, zinc and copper found in green oat plants, as well as a decrease of the content of iron and manganese with increasing waste dose. These results may be explained by lower absorptions of iron and manganese because of the antagonistic effect created by high amounts of calcium and magnesium, as well as by the presence of copper and zinc. .

scholarly journals MgCaCO3Versus CaCO3in Peritoneal Dialysis Patients – a Cross-over Pilot Trial

2015 ◽  
Vol 35 (1) ◽  
pp. 31-34 ◽  
Author(s):  
Baigalmaa Evsanaa ◽  
Irene Liu ◽  
Babak Aliazardeh ◽  
Sara Mahdavi ◽  
Gursarn Bajwa ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Calcium Carbonate ◽  
Pilot Study ◽  
Serum Magnesium ◽  
Pilot Trial ◽  
Magnesium Carbonate ◽  
Serum Phosphate ◽  
Phosphate Binders ◽  
Serum Phosphate Level ◽  
Calcium Magnesium

BackgroundDespite adverse effects such as constipation, vascular calcification, and hypercalcemia, calcium-based salts are relatively affordable and effective phosphate binders that remain in widespread use in the dialysis population. We conducted a pilot study examining whether the use of a combined magnesium/calcium-based binder was as effective as calcium carbonate at lowering serum phosphate levels in peritoneal dialysis (PD) patients.MethodsThis was a cross-over, investigator-masked pilot study in which prevalent PD patients received calcium carbonate alone (200 mg calcium per tablet) or calcium magnesium carbonate (100 mg calcium, 85 mg magnesium per tablet). Primary outcome was serum phosphate level at 3 months. Analysis was as per protocol.ResultsTwenty patients were recruited, 17 completed the study. Mean starting dose was 11.35 ± 7.04 pills per day of MgCaCO3and 9.00 ± 4.97 pills per day of CaCO3. Mean phosphate levels fell from 2.13 mmol/L to 2.01 mmol/L (95% confidence interval (CI): 1.76 – 2.30, p = 0.361) in the MgCaCO3group, and 1.81 mmol/L (95% CI: 1.56 – 2.0, p = 0.026) in the CaCO3alone group. Six (35%) patients taking MgCaCO3and 9 (54%) taking CaCO3alone achieved Kidney Disease Outcomes Quality Initiative (KDOQI) serum phosphate targets at 3 months. Diarrhea developed in 9 patients taking MgCaCO3and 3 taking CaCO3. Serum magnesium exceeded 1.4 mmol/L in 5 patients taking MgCaCO3while serum calcium exceeded 2.65 mmol/L in 3 patients receiving CaCO3. When compared to the initial dose, the prescribed dose at 3 months was reduced by 44% (to 6.41 tablets/day) in the MgCaCO3group and by 8% (to 8.24 pills per day) in the CaCO3alone group.ConclusionCompared with CaCO3alone, the preparation and dose of MgCaCO3used in this pilot study was no better at lowering serum phosphate levels in PD patients, and was associated with more dose-limiting side effects.

Sign in / Sign up

Export Citation Format

Share Document