scholarly journals Evidence-based treatment for adult women with child abuse-related Complex PTSD: a quantitative review

2014 ◽  
Vol 5 (1) ◽  
pp. 23613 ◽  
Author(s):  
Ethy Dorrepaal ◽  
Kathleen Thomaes ◽  
Adriaan W. Hoogendoorn ◽  
Dick J. Veltman ◽  
Nel Draijer ◽  
...  
2010 ◽  
Vol 71 (12) ◽  
pp. 1636-1644 ◽  
Author(s):  
Kathleen Thomaes ◽  
Ethy Dorrepaal ◽  
Nel Draijer ◽  
Michiel B. de Ruiter ◽  
Anton J. van Balkom ◽  
...  

2012 ◽  
Vol 42 (11) ◽  
pp. 2337-2349 ◽  
Author(s):  
K. Thomaes ◽  
E. Dorrepaal ◽  
N. Draijer ◽  
M. B. de Ruiter ◽  
B. M. Elzinga ◽  
...  

BackgroundFunctional neuroimaging studies have shown increased Stroop interference coupled with altered anterior cingulate cortex (ACC) and insula activation in post-traumatic stress disorder (PTSD). These brain areas are associated with error detection and emotional arousal. There is some evidence that treatment can normalize these activation patterns.MethodAt baseline, we compared classic and emotional Stroop performance and blood oxygenation level-dependent responses (functional magnetic resonance imaging) of 29 child abuse-related complex PTSD patients with 22 non-trauma-exposed healthy controls. In 16 of these patients, we studied treatment effects of psycho-educational and cognitive behavioural stabilizing group treatment (experimental treatment; EXP) added to treatment as usual (TAU) versus TAU only, and correlations with clinical improvement.ResultsAt baseline, complex PTSD patients showed a trend for increased left anterior insula and dorsal ACC activation in the classic Stroop task. Only EXP patients showed decreased dorsal ACC and left anterior insula activation after treatment. In the emotional Stroop contrasts, clinical improvement was associated with decreased dorsal ACC activation and decreased left anterior insula activation.ConclusionsWe found further evidence that successful treatment in child abuse-related complex PTSD is associated with functional changes in the ACC and insula, which may be due to improved selective attention and lower emotional arousal, indicating greater cognitive control over PTSD symptoms.


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