scholarly journals The Role of Attenuation and Land Management in Small Catchments to Remove Sediment and Phosphorus: A Modelling Study of Mitigation Options and Impacts

Water ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1227 ◽  
Author(s):  
Russell Adams ◽  
Paul Quinn ◽  
Nick Barber ◽  
Sim Reaney
Keyword(s):  
Beneficial Effect ◽  
Natural Attenuation ◽  
Sediment Traps ◽  
Small Decrease ◽  
Flood Peak ◽  
Actual Type ◽  
Flood Flows ◽  
Small Catchments ◽  
Catchment Runoff

It is well known that soil, hillslopes, and watercourses in small catchments possess a degree of natural attenuation that affects both the shape of the outlet hydrograph and the transport of nutrients and sediments. The widespread adoption of Natural Based Solutions (NBS) practices in the headwaters of these catchments is expected to add additional attenuation primarily through increasing the amount of new storage available to accommodate flood flows. The actual type of NBS features used to add storage could include swales, ditches, and small ponds (acting as sediment traps). Here, recent data collected from monitored features (from the Demonstration Test Catchments project in the Newby Beck catchment (Eden) in northwest England) were used to provide first estimates of the percentages of the suspended sediment (SS) and total phosphorus (TP) loads that could be trapped by additional features. The Catchment Runoff Attenuation Flux Tool (CRAFT) was then used to model this catchment (Newby Beck) to investigate whether adding additional attenuation, along with the ability to trap and retain SS (and attached P), will have any effect on the flood peak and associated peak concentrations of SS and TP. The modelling tested the hypothesis that increasing the amount of new storage (thus adding attenuation capacity) in the catchment will have a beneficial effect. The model results implied that a small decrease of the order of 5–10% in the peak concentrations of SS and TP was observable after adding 2000 m3 to 8000 m3 of additional storage to the catchment.

On the role of tin underlays for the prevention of thermal grooving in thin gold films

1986 ◽  
Vol 44 ◽  
pp. 732-733
Author(s):  
Jin Young Kim ◽  
R. E. Hummel ◽  
R. T. DeHoff
Keyword(s):  
Thin Film ◽  
Free Surface ◽  
Grain Boundary ◽  
Beneficial Effect ◽  
Failure Mechanism ◽  
Failure Mechanisms ◽  
Distinct Advantage ◽  
Gold Films ◽  
Gold Thin Film

Gold thin film metallizations in microelectronic circuits have a distinct advantage over those consisting of aluminum because they are less susceptible to electromigration. When electromigration is no longer the principal failure mechanism, other failure mechanisms caused by d.c. stressing might become important. In gold thin-film metallizations, grain boundary grooving is the principal failure mechanism.Previous studies have shown that grain boundary grooving in gold films can be prevented by an indium underlay between the substrate and gold. The beneficial effect of the In/Au composite film is mainly due to roughening of the surface of the gold films, redistribution of indium on the gold films and formation of In2O3 on the free surface and along the grain boundaries of the gold films during air annealing.

The role of nanoscale aggregation of ferrihydrite and amorphous silica in the natural attenuation of contaminant metals at mill tailings sites

2021 ◽  
Vol 298 ◽  
pp. 207-226
Author(s):  
Keisuke Kawamoto ◽  
Hiroki Yokoo ◽  
Asumi Ochiai ◽  
Yuriko Nakano ◽  
Ayaka Takeda ◽  
...  
Keyword(s):  
Amorphous Silica ◽  
Natural Attenuation ◽  
Mill Tailings ◽  
Contaminant Metals

Clinical and Biochemical Outcomes Following EEG Neurofeedback Training in Traumatic Brain Injury in the Context of Spontaneous Recovery

2017 ◽  
Vol 49 (6) ◽  
pp. 433-440 ◽  
Author(s):  
Cathlyn N. Bennett ◽  
Rajnish K. Gupta ◽  
Puttachandra Prabhakar ◽  
Rita Christopher ◽  
Somanna Sampath ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Beneficial Effect ◽  
Posttraumatic Stress ◽  
Perceived Stress ◽  
Spontaneous Recovery ◽  
Serum Cortisol ◽  
Neurofeedback Training ◽  
Eeg Neurofeedback

It has been found that reduction of posttraumatic stress symptoms is positively associated with the reduction of postconcussive symptoms. Cortisol is commonly used as a biomarker of stress. Understanding the role of posttraumatic stress and cortisol in symptom reduction has implication for neuropsychological rehabilitation particularly in the context of spontaneous recovery. Objective. The aim of the research was to study the effectiveness of EEG neurofeedback training on clinical symptoms, perceived stress, and cortisol in traumatic brain injury (TBI) patients in the context of spontaneous recovery. Methods. The design was an experimental longitudinal design with the pre-post comparison. The sample comprised 60 patients with the diagnosis of TBI—30 patients in the neurofeedback training (NFT) group and 30 patients in the treatment as usual group (TAU) group. Half of the patients were recruited within 6 months of injury to study the role of spontaneous recovery and the other half were recruited in the 12 to 18 months postinjury phase. Alpha-theta training was given to the NFT group over 20 sessions. Pre and post comparisons were made on clinical symptom rating, perceived stress, and serum cortisol levels. Results. The results indicate significant differences in symptom reporting and perceived stress between the NFT and TAU groups. Significant differences were also seen in cortisol levels with implications for the acute recovery phase. Conclusion. Alpha-theta NFT has a beneficial effect on symptom reduction as well as perceived stress. It also has a beneficial effect on levels of serum cortisol, corroborating these findings.

scholarly journals The role of antecedent groundwater heads in controlling transient aquifer storage and flood peak attenuation in karst watersheds

2018 ◽  
Vol 44 (1) ◽  
pp. 77-87 ◽  
Author(s):  
Patricia Spellman ◽  
Jason Gulley ◽  
Jonathan B. Martin ◽  
Jeremy Loucks
Keyword(s):  
Flood Peak ◽  
Aquifer Storage ◽  
Flood Peak Attenuation

Abstract MP20: Optogenetic Control Of Pip2 To Assess Mechanisms Regulating The Epithelial Sodium Channel

Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Crystal R Archer ◽  
Amanpreet Kaur ◽  
Tarek Mohamed ◽  
James D Stockand
Keyword(s):  
Binding Sites ◽  
Hek293 Cells ◽  
Proper Function ◽  
Small Decrease ◽  
Kidney Tubules ◽  
Wild Type ◽  
N Terminus ◽  
Patch Clamp Electrophysiology ◽  
G Protein Coupled

The epithelial Na + channel (ENaC) plays a key role in Na + transport in epithelial linings to include the lung, colon and kidney. In the distal kidney tubules, ENaC regulates Na + reabsorption and blood volume. Thus, dysfunctions in signaling pathways regulating ENaC activity are linked to hypertension or hypotension. Phosphatidylinositol 4,5-bisphosphate (PIP 2 ) is a target of the G protein coupled receptor P2Y2 pathway, and is necessary for the proper function of ENaC. This nonvoltage-gated trimeric channel is comprised of α, β, and γ subunits. We recently described two intracellular PIP 2 binding sites on the N termini of β-, and γ-ENaC, with moderate μM affinity. Here, we report the functional effects on ENaC containing a combination of mutations to those PIP 2 binding sites, by controlled depletion of PIP 2 . We used a CIBN/CRY2-5-ptase optogenetic dimerization system to deplete PIP 2 levels in HEK293 cells transiently expressing wild type (wt) ENaC or the mutant ENaC constructs. A fluorescent Na + indicator, was used to monitor ENaC activity by tracking the relative intracellular Na + levels. Upon optogenetic-controlled depletion of PIP 2 , Na + levels decreased in cells expressing wt ENaC. Mutations to the PIP 2 sites of ENaC were expected to have no change in Na + levels upon PIP 2 depletion due to the disruption of PIP 2 binding. As a control, mutations to non-PIP 2 binding sites were included, and were expected to have decreased Na + levels similar to wt ENaC. Interestingly, mutation of each independent PIP 2 site resulted in only a small decrease of intracellular Na + , compared to wt ENaC. However, mutations throughout the entire N-terminus of β-ENaC, including the PIP 2 binding site, resulted in a significant increase of Na + upon PIP 2 depletion. We performed patch clamp electrophysiology and found that the ENaC recordings corresponded to the Na + fluctuations. These data suggest that the residues surrounding the PIP 2 binding sites play a significant role in the affinity of PIP 2 for ENaC. The role of these other domains in PIP 2 binding is still under investigation.

Antidepressants in Cancer Pain

1991 ◽  
Vol 7 (4) ◽  
pp. 42-44 ◽  
Author(s):  
Alberto E. Panerai ◽  
Mauro Bianchi ◽  
Paola Sacerdote ◽  
Carla Ripamonti ◽  
Vittorio Ventafridda ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cancer Pain ◽  
Beneficial Effect ◽  
Nerve Injury ◽  
Analgesic Effect ◽  
Tricyclic Antidepressants ◽  
Antidepressant Drugs ◽  
Depressive Illness ◽  
Morphine Analgesia

Studies conducted in recent years have helped define the role of antidepressant drugs in the management of cancer pain. The anti-nociceptive action of these agents seems to be independent of beneficial effect on depression or mood. Among antidepressant drugs, those of the tricyclic class are preferred when an analgesic effect is sought. Their primary application is for pain due to nerve injury, so-called “neuropathic pain”. Although the co-administration of tricyclic antidepressants may increase plasma morphine concentrations, any potentiation of morphine analgesia is thought not to be due to an increased bioavailability of the opiate, but to an intrinsic analgesic effect of antidepressants. On this basis, the use of antidepressants in combination with opioids for the treatment of cancer pain is suitable when a component of deafferentation is present or when there is concomitant depressive illness.

scholarly journals A study to evaluate the role of suction drains in orthopedic surgery

1970 ◽  
Vol 9 (2) ◽  
pp. 91-94 ◽  
Author(s):  
GP Khanal ◽  
R Rijal ◽  
BP Shrestha ◽  
NK Karn ◽  
P Chaudhary
Keyword(s):  
Beneficial Effect ◽  
Orthopedic Surgery ◽  
Postoperative Infection ◽  
Wound Care ◽  
Demographic Data ◽  
Superficial Infection ◽  
Postoperative Wound ◽  
Suction Drain ◽  
One Year

Background: There is controversy in routine use of suction drain in orthopedic surgeries. Devastating postoperative infection and years of treatment had forced on extra measures of postoperative wound care and use of drains. Objective: To find out the necessity of intraoperative drains in routine orthopedic surgery. Methods: Thirty patients were enrolled in the study. All of the patients were followed up on 2nd, 14th days and 3 monthly till one year of period. All the demographic data and preoperative investigations and intraoperative and postoperative parameters were recorded in standard proforma. Data were analysed using appropriate statistical method. Results: All the patients were followed up to one year period. Six patients had superficial infection on 2nd postoperative day. They were managed with antibiotics and no patient showed signs of infections on 14th postoperative day and thereafter. No patient needed postoperative reinforcement of dressing. Conclusion: Routine use of intraoperative drain in hip surgeries has beneficial effect of decreasing reinforcement of postoperative dressing. Keywords: orthopedic surgery; suction drain; BPKIHS DOI: http://dx.doi.org/10.3126/hren.v9i2.4980 Health Renaissance 2011: Vol.9 (No.2): 91-94

scholarly journals n-3 Polyunsaturated Fatty Acids and Their Derivates Reduce Neuroinflammation during Aging

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 647 ◽  
Author(s):  
Corinne Joffre ◽  
Anne-Laure Dinel ◽  
Mathilde Chataigner ◽  
Véronique Pallet ◽  
Sophie Layé
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Beneficial Effect ◽  
Life Quality ◽  
Inflammatory Signaling ◽  
Resolution Of Inflammation ◽  
Loss Of Life ◽  
Immunomodulatory Properties ◽  
The Brain

Aging is associated to cognitive decline, which can lead to loss of life quality, personal suffering, and ultimately neurodegenerative diseases. Neuroinflammation is one of the mechanisms explaining the loss of cognitive functions. Indeed, aging is associated to the activation of inflammatory signaling pathways, which can be targeted by specific nutrients with anti-inflammatory effects. Dietary n-3 polyunsaturated fatty acids (PUFAs) are particularly attractive as they are present in the brain, possess immunomodulatory properties, and are precursors of lipid derivates named specialized pro-resolving mediators (SPM). SPMs are crucially involved in the resolution of inflammation that is modified during aging, resulting in chronic inflammation. In this review, we first examine the effect of aging on neuroinflammation and then evaluate the potential beneficial effect of n-3 PUFA as precursors of bioactive derivates, particularly during aging, on the resolution of inflammation. Lastly, we highlight evidence supporting a role of n-3 PUFA during aging.

Sign in / Sign up

Export Citation Format

Share Document