scholarly journals Current Choroidal Imaging Findings in Central Serous Chorioretinopathy

Vision ◽  
2020 ◽  
Vol 4 (4) ◽  
pp. 44
Author(s):  
Gideon Nkrumah ◽  
Dmitrii S. Maltsev ◽  
Paez-Escamilla A. Manuel ◽  
Mohammed A. Rasheed ◽  
Marianno Cozzi ◽  
...  
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Relevant Literature ◽  
Imaging Biomarkers ◽  
Wide Field ◽  
Imaging Findings ◽  
En Face ◽  
Choroidal Imaging ◽  
Nasal Region ◽  
En Face Imaging

Background: Central serous chorioretinopathy (CSCR) is a chorioretinal disease affecting mostly middle age males. It is marked by the serous detachment of the neurosensory layer at the macula. This review of the literature provides a framework of the current characteristic/relevant imaging findings of CSCR. Although the pathogenesis of CSCR is unclear, the choroid plays a major role and its changes are fundamental to the diagnosis and treatment of CSCR. Methods: A systematic literature search focusing on current multimodal imaging for CSCR was performed. Only articles reporting on original clinical data were selected, studies in a language other than English were included only if an English abstract was provided. Additional sources included articles cited in the references list of the first selected articles. We deduced imaging findings based on current and relevant literature on the topic. Results: We found that sub foveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) were greater in eyes with acute CSCR than in eyes with chronic CSCR or normal eyes. There was increased choroidal thickness (CT) in the macula compared to peripapillary region. In healthy eyes, the highest CVI was found in the nasal region followed by the inferior, temporal, and superior quadrant. The area with the least CVI was the macula. In eyes with CSCR, 100% had asymmetric dominant vortex veins compared to 38% in normal eyes. Conclusion: Choroidal imaging has advanced the diagnosis of CSCR. This has led to numerous imaging biomarkers like CVI, CT, and hyper-reflective dots for early detection and possible prognostication of CSCR. More techniques like wide field scans and en face imaging are being employed to characterize the choroid in CSCR.

scholarly journals Combined 60° Wide-Field Choroidal Thickness Maps and High-Definition En Face Vasculature Visualization Using Swept-Source Megahertz OCT at 1050 nm

2015 ◽  
Vol 56 (11) ◽  
pp. 6284 ◽  
Author(s):  
Kathrin J. Mohler ◽  
Wolfgang Draxinger ◽  
Thomas Klein ◽  
Jan Philip Kolb ◽  
Wolfgang Wieser ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Wide Field ◽  
High Definition ◽  
Swept Source ◽  
En Face

scholarly journals Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 861
Author(s):  
Niroj Kumar Sahoo ◽  
Sumit Randhir Singh ◽  
Oliver Beale ◽  
Gideon Nkrumah ◽  
Mohammed Abdul Rasheed ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Observational Study ◽  
Negative Correlation ◽  
Early Treatment ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Outer Ring ◽  
Nasal Region ◽  
Healthy Eyes ◽  
Fellow Eyes

Background: To map the choroidal vascularity index and compare two eyes in patients with unilateral central serous chorioretinopathy (CSCR). Methods: This was a retrospective, observational study performed in patients with unilateral CSCR. Choroidal thickness (CT) and Choroidal vascularity index (CVI) were measured and mapped in various zones according to the early treatment diabetic retinopathy (ETDRS) grid. Results: A total of 20 CSCR patients (20 study and 20 fellow eyes) were included in the study. Outer nasal region CT was seen to be significantly lower than central CT (p = 0.042) and inner nasal CT (p = 0.007); outer ring CT was significantly less than central (p = 0.04) and inner ring (p = 0.01) CT in CSCR eyes. On potting all the CVI values against the corresponding CT values, a positive correlation was seen in CSCR eyes (r = 0.54, p < 0.01), which was slightly weaker in fellow eyes (r = 0.3, p < 0.01) and a negative correlation was seen in healthy eyes (r = −0.262, p < 0.01). Conclusions: Correlation between CVI and CT was altered in CSCR eyes as compared to fellow and normal eyes with increasing CVI towards the center of the macula and superiorly in CSCR eyes.

scholarly journals Optical coherence tomography angiography of flat irregular pigment epithelial detachments in central serous chorioretinopathy

2020 ◽  
pp. bjophthalmol-2019-315318 ◽  
Author(s):  
Tingting Liu ◽  
Wei Lin ◽  
Shuping Zhou ◽  
Xiangjuan Meng
Keyword(s):  
Optical Coherence Tomography ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Optical Coherence Tomography Angiography ◽  
Chinese Patients ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Pigment Epithelial ◽  
Face Area ◽  
En Face

BackgroundTo identify and analyse the character and relationship between flat irregular pigment epithelial detachment feature (FIPED), choroidal thickness and choroidal neovascularisation (CNV) network seen on optical coherence tomography angiography (OCTA) in eyes with central serous chorioretinopathy (CSCR) in Chinese patients.MethodIn the present study, 152 eyes of 144 Chinese patients, who were previously diagnosed with CSCR, were retrospectively studied. Patients’ baseline characteristics, the course of CSCR, best-corrected visual acuity, the pattern of CNV on OCTA, FIPED and choroidal thickness detected by enhanced depth imaging-OCT (EDI-OCT) were analysed.ResultsIt was disclosed that 7.23% of CSCR patients had CNV. Age and the course of CSCR were found to be correlated with the occurrence of CNV. Among the eyes with CNV network (11 eyes), 100% of them had FIPED, whereas, among the eyes without CNV (141 eyes), 18.04% had FIPED. The maximum width and en-face area of PED were greater in the CNV group compared with that in the non-CNV group (p<0.001). It also was revealed that female gender and a poor vision were risk factors for CNV in eyes with CSCR. The choroidal thickness detected by EDI-OCT was also statistically significant between eyes with CNV and eyes without CNV. The patients who have CNV complicated with FIPED are susceptible to have low vision.ConclusionThe present research demonstrated that the majority of CNV cases were linked to FIPED, and the thinner thickness of choroid. The greater width and en-face area of PED may point towards the presence of an underlying CNV network.

scholarly journals Imaging Familial and Sporadic Neurodegenerative Disorders Associated with Parkinsonism

2021 ◽  
Author(s):  
David J. Brooks
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Neurodegenerative Disorders ◽  
Lewy Body Dementia ◽  
Imaging Biomarkers ◽  
Imaging Findings ◽  
Subclinical Disease ◽  
Similarities And Differences ◽  
Potential Use

AbstractIn this paper, the structural and functional imaging changes associated with sporadic and genetic Parkinson’s disease and atypical Parkinsonian variants are reviewed. The role of imaging for supporting diagnosis and detecting subclinical disease is discussed, and the potential use and drawbacks of using imaging biomarkers for monitoring disease progression is debated. Imaging changes associated with nonmotor complications of PD are presented. The similarities and differences in imaging findings in Lewy body dementia, Parkinson’s disease dementia, and Alzheimer’s disease are discussed.

scholarly journals Macular pigment optical density in central serous chorioretinopathy

2021 ◽  
Vol 13 ◽  
pp. 251584142199719
Author(s):  
Burcu Polat Gultekin ◽  
Esra Sahli
Keyword(s):  
Confidence Interval ◽  
Optical Density ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Macular Pigment ◽  
Central Retinal Thickness ◽  
Macular Pigment Optical Density ◽  
Chronic Central Serous Chorioretinopathy ◽  
Acute Central Serous Chorioretinopathy

Purpose: The aim of our study was to evaluate the macular pigment optical density in patients with acute and chronic central serous chorioretinopathy and to describe the association between central retinal thickness and choroidal thickness with the macular pigment optical density. Materials and Methods: Eyes with acute central serous chorioretinopathy and chronic central serous chorioretinopathy (patients, who were diagnosed as having disease activity for 6 months) were included in this study. Macular pigment was measured using the heterochromatic flicker technique of the MPS II device for both eyes in patients with acute and chronic central serous chorioretinopathy and in control subjects. Results: Twenty-seven eyes with acute central serous chorioretinopathy, 23 eyes with chronic central serous chorioretinopathy, and 25 control eyes were enrolled. The mean macular pigment optical density in chronic central serous chorioretinopathy (0.480 ± 0.16 density unit (95% confidence interval: 0.390–0.570) was found to be significantly lower than in the control eyes (0.571 ± 0.128 density unit) (95% confidence interval: 0.480–0.670) ( p = 0.007). In correlation analysis, no significant association was detected between the central retinal thickness, choroidal thickness, and macular pigment optical density values in central serous chorioretinopathy group ( p = 0.31, p = 0.71). Conclusion: Macular pigment optical density levels were significantly lower in chronic central serous chorioretinopathy patients than in controls, possibly due to degeneration of the neurosensorial retina, as a result of the long-term persistence of subretinal fluid. There was not a significant correlation between choroidal thickness and macular pigment optical density levels in central serous chorioretinopathy group.

Sensitivity and specificity of choroidal thickness measurement by EDI-OCT for central serous chorioretinopathy diagnosis

2020 ◽  
Author(s):  
Javier Orduña-Azcona ◽  
Elia Pérez-Fernández ◽  
Ana M. Guadilla ◽  
Sofía De Manuel-Triantafilo ◽  
Laura Modamio ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Thickness Measurement

Quasi-simultaneous OCT en-face imaging with two different depth resolutions

2003 ◽  
Vol 36 (14) ◽  
pp. 1696-1702 ◽  
Author(s):  
Adrian Gh Podoleanu ◽  
Radu G Cucu ◽  
Richard B Rosen ◽  
George M Dobre ◽  
John A Rogers ◽  
...  
Keyword(s):  
En Face ◽  
En Face Imaging
Sign in / Sign up

Export Citation Format

Share Document