Wide‐field choroidal thickness and vascularity index in myopes and emmetropes

2021 ◽  
Author(s):  
Mohsen Heirani ◽  
Masoud Khorrami‐Nejad
Keyword(s):  
Choroidal Thickness ◽  
Wide Field

scholarly journals Combined 60° Wide-Field Choroidal Thickness Maps and High-Definition En Face Vasculature Visualization Using Swept-Source Megahertz OCT at 1050 nm

2015 ◽  
Vol 56 (11) ◽  
pp. 6284 ◽  
Author(s):  
Kathrin J. Mohler ◽  
Wolfgang Draxinger ◽  
Thomas Klein ◽  
Jan Philip Kolb ◽  
Wolfgang Wieser ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Wide Field ◽  
High Definition ◽  
Swept Source ◽  
En Face

Choroidal Thickness and Structural Glaucoma Parameters in Glaucomatous, Preperimetric Glaucomatous, and Healthy Eyes using Swept-Source OCT

2017 ◽  
Vol 27 (5) ◽  
pp. 548-554 ◽  
Author(s):  
Handan Akil ◽  
Mayss Al-Sheikh ◽  
Khalil Ghasemi Falavarjani ◽  
Brian Francis ◽  
Vikas Chopra
Keyword(s):  
Nerve Fiber ◽  
Choroidal Thickness ◽  
Wide Field ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Swept Source ◽  
Nerve Fiber Layer ◽  
Rnfl Thickness ◽  
The Mean ◽  
Healthy Eyes

Purpose To evaluate choroidal thickness (CT) and its relationship with retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer thickness (GCIPLT) in glaucomatous, preperimetric glaucomatous, and healthy eyes using swept-source optical coherence tomography (SS-OCT). Methods Fifty eyes with primary open-angle glaucoma, 20 eyes with preperimetric glaucoma, and 20 age-matched healthy eyes were enrolled. Three-dimensional wide-field (12 × 9 mm) images were obtained using a SS-OCT instrument. Peripapillary CT and RNFL thickness, as well as macular CT and GCIPLT, were recorded. The correlation of the CT with nerve fiber layer and GCIPLT measurements was assessed. The association between CT and potential confounding variables including age, sex, axial length, intraocular pressure, and central corneal thickness was also examined. Results Mean peripapillary CTs were 111.7 ± 41.7, 127.7 ± 40.1, and 120.8 ± 35.4 μm in glaucomatous, preperimetric glaucomatous, and normal eyes, respectively. There was statistically significant but weak correlation for the mean RNFL and mean peripapillary CT in glaucomatous subjects (r = 0.341, p = 0.04). There was a significant correlation between RNFL thickness and peripapillary CT in 1, 2, 5, and 6 clock hours of glaucomatous eyes (r = 0.410, p = 0.005; r = 0.316, p = 0.03; r = 0.346, p = 0.02; r = 0.35, p = 0.04, respectively). Mean macular CT was 181.5 ± 70.5, 187.4 ± 65.5, and 185.4 ± 76.4 μm in glaucomatous, preperimetric glaucomatous, and healthy eyes, respectively (p = 0.7). There was no statistically significant correlation between the mean GCIPLT and mean macular CT in all subjects (p>0.05). Conclusions Choroidal thinning and its correlation with other parameters in patients with glaucoma should be further investigated with the proprietary software of SS-OCT.

Choroidal thickness and vessel pattern in myopic eyes with dome-shaped macula

2021 ◽  
pp. bjophthalmol-2021-319066
Author(s):  
Pierre Negrier ◽  
Aude Couturier ◽  
David Gaucher ◽  
Sara Touhami ◽  
Guillaume Le Guern ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retrospective Study ◽  
Retinal Detachment ◽  
Choroidal Thickness ◽  
Serous Retinal Detachment ◽  
Wide Field ◽  
Macular Area ◽  
The Mean ◽  
Choroidal Vessels ◽  
Bulge Height

AimTo analyse the choroidal thickness (CT) and vessel pattern of myopic patients with dome-shaped macula (DSM) and their association with the DSM axis and serous retinal detachment (SRD).MethodsRetrospective study. The CT and vessel pattern were assessed on optical coherence tomography (OCT), OCT-angiography and ultra-wide-field photography.Results27 eyes of 18 subjects (mean age: 65 years) were included. Compared with the 11 eyes (41%) with horizontal DSM, the 16 eyes (59%) with vertical DSM had a shorter axial length (25.8±2 mm vs 28.3±2.5 mm; p=0.01), a higher mean macular bulge height (624.4±207 µm vs 255.4±160.3 µm; p=0.0001) and a thicker CT (183.1±91.1 µm vs 72±38.3 µm; p<0.001). Large choroidal vessels crossed the macular area in 75% of eyes with vertical DSM vs 27% of eyes with horizontal DSM (p=0.02), whereas a watershed zone framing the macula was more often seen in horizontal DSM (72% vs 25%, p=0.02). Thirteen eyes (48%) had an SRD that was not associated with the DSM axis, the mean bulge height, the CT or the vessel pattern.ConclusionThe presence of an SRD did not correlate with the DSM axis, the CT or the vessel pattern. However, the rate of large choroidal vessels crossing the macula was higher in vertical DSM than in horizontal DSM.

Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia

2021 ◽  
pp. bjophthalmol-2021-319540
Author(s):  
Jade Y. Moon ◽  
Itika Garg ◽  
Ying Cui ◽  
Raviv Katz ◽  
Ying Zhu ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Optical Coherence Tomography Angiography ◽  
Foveal Avascular Zone ◽  
Systemic Hypertension ◽  
Wide Field ◽  
Optical Coherence ◽  
Swept Source ◽  
Retinal Microvasculature ◽  
Capillary Plexus

Background/aimsPathological myopia (PM) is a leading cause of blindness worldwide. We aimed to evaluate microvascular and chorioretinal changes in different stages of myopia with wide-field (WF) swept-source (SS) optical coherence tomography angiography (OCTA).MethodsThis prospective cross-sectional observational study included 186 eyes of 122 patients who had undergone imaging between November 2018 and October 2020. Vessel density (VD) and vessel skeletonised density (VSD) of superficial capillary plexus, deep capillary plexus and whole retina, as well as foveal avascular zone parameters, retinal thickness (RT) and choroidal thickness (CT), were calculated.ResultsThis study evaluated 75 eyes of 48 patients with high myopia (HM), 43 eyes of 31 patients with mild to moderate myopia and 68 eyes of 53 age-matched controls. Controlling for age and the presence of systemic hypertension, we found that HM was associated with decrease in VD and VSD in all layers on 12×12 mm² scans. Furthermore, HM was associated with a VD and VSD decrease in every Early Treatment Diabetic Retinopathy Study grid, with a larger decrease temporally (βVD=−0.39, βVSD=−10.25, p<0.01). HM was associated with decreased RT and CT. Reduction in RT was outside the macular region, while reduction in CT was in the macular region.ConclusionUsing WF SS-OCTA, we identified reduction in microvasculature and structural changes associated with myopia. Decrease in VD and VSD was greater in the temporal quadrant, and reductions in RT and CT were uneven across the retina. Further work may help identify risk factors for the progression of PM and associated vision-threatening complications.

scholarly journals Wide-field choroidal thickness profile in healthy eyes

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Mohammed Abdul Rasheed ◽  
Sumit Randhir Singh ◽  
Alessandro Invernizzi ◽  
Carlo Cagini ◽  
Abhilash Goud ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Wide Field ◽  
Thickness Profile ◽  
Healthy Eyes

Wide-field choroidal vascular analysis in central serous chorioretinopathy

2020 ◽  
pp. 112067212096345
Author(s):  
Sumit Randhir Singh ◽  
Alessandro Invernizzi ◽  
Mohammed Abdul Rasheed ◽  
Carlo Cagini ◽  
Abhilash Goud ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Regression Analysis ◽  
Regional Variation ◽  
Choroidal Thickness ◽  
Wide Field ◽  
P Values ◽  
Vertical Meridian ◽  
Factors Influencing ◽  
Choroidal Vessel ◽  
Fellow Eyes

Purpose: To report the wide-field choroidal vessel analysis in central serous chrorioretinopathy (CSCR) and their fellow eyes. Methods: Wide-field optical coherence tomography (WF-OCT) images (55°) were obtained using Spectralis HRA + OCT (Heidelberg Engineering, Germany) in extremes of gazes in all quadrants and manual montages were created to obtain wide field images up to equator. Choroidal thickness (CT), large choroidal vessel layer thickness (LCVT), and choroidal vascularity index (CVI) were calculated in macular segment (twice the disc to fovea distance) and all four quadrants. Regression analysis was performed to identify the factors influencing CVI. Results: Thirty-one patients of CSCR including 39 eyes of CSCR (32 chronic, 7 acute) and 23 fellow eyes were analyzed. CT and LCVT were significantly higher in submacular choroid than all extramacular segments in both CSCR and fellow eyes (all p values <0.01). CVI varied significantly in different segments in horizontal ( p < 0.01 in both) and vertical meridian ( p < 0.01 and p = 0.01 respectively) in CSCR and fellow eyes. Both CSCR and fellow eyes had highest CVI in nasal segment with minimum CVI in macular segment. Age ( p = 0.85), gender ( p = 0.39), chronicity of the disease (acute vs chronic, p = 0.57), axial length ( p = 0.67), SBP ( p = 0.81), and DBP ( p = 0.94) were not significantly correlated to CVI. Conclusion: CVI shows significant regional variation with macular segment showing the lowest CVI whereas nasal segments have highest CVI in both CSCR and their fellow eyes. On the contrary, submacular segment has highest CT and LCVT with taper towards periphery in both CSCR and fellow eyes.

scholarly journals Wide-field Swept-source OCT Analysis of Interocular Symmetry of Choroidal Thickness in Subjects with Uncomplicated Pachychoroid

2021 ◽  
Author(s):  
Min-Su Kim ◽  
Hyung-Bin Lim ◽  
Woo-Hyuk Lee ◽  
Yeo-Kyoung Won ◽  
Gi-Yup Nam ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Anatomical Variation ◽  
Correlation Coefficients ◽  
Wide Field ◽  
Macular Area ◽  
Clinical Factor ◽  
Swept Source ◽  
Peripheral Area ◽  
Peripheral Areas ◽  
The Right

Abstract Purpose: To study the bilateral choroidal thickness (CT) symmetry and difference in uncomplicated pachychoroid subjects using wide-field swept-source optical coherence tomography (SS-OCT).Methods: All subjects underwent a wide-field 16-mm 1-line scan using SS-OCT. Bilateral CT was measured at, and compared among, the following 12 points: 3 points at 900-µm intervals from the nasal optic disc margin (nasal peripapillary area), 1 point at the subfovea, 6 points at 900-µm intervals from the fovea to the nasal and temporal areas (macular area), and 2 peripheral points 5,400 and 8,100 µm from the fovea (peripheral area). Associations between interocular CT differences in the various measurement areas and clinical factors were analyzed.Results: There was no statistically significant differences in CT between the right and left eyes in any area (all p > 0.05); they all showed significant positive correlations (all p < 0.01). However, the correlation coefficients (ρ) were smaller for the nasal peripapillary and peripheral areas compared to the macular area. In addition, the interocular axial length differences were significantly associated with interocular CT differences in the macular area, but not in the nasal peripapillary or peripheral area. No other clinical factor was associated with interocular CT differences in any area.Conclusions: The CTs in each region were bilaterally symmetrical in subjects with uncomplicated pachychoroid. However, interocular difference in CT increased from the center to the periphery, indicating that the anatomical variation of the nasal peripapillary and peripheral choroid was greater than that of the macula.

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