scholarly journals Drug Delivery Strategies for Antivirals against Hepatitis B Virus

Viruses ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 267 ◽  
Author(s):  
Latavia Singh ◽  
Sunaina Indermun ◽  
Mershen Govender ◽  
Pradeep Kumar ◽  
Lisa du Toit ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
B Virus ◽  
Delivery Strategies

Drug Delivery Systems and Liver Targeting for the Improved Pharmacotherapy of the Hepatitis B Virus (HBV) Infection

2010 ◽  
Vol 27 (7) ◽  
pp. 1184-1202 ◽  
Author(s):  
María L. Cuestas ◽  
Verónica L. Mathet ◽  
José R. Oubiña ◽  
Alejandro Sosnik
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Hbv Infection ◽  
Liver Targeting ◽  
B Virus

Modular Hepatitis B Virus-like Particle Platform for Biosensing and Drug Delivery

ACS Nano ◽  
2020 ◽  
Vol 14 (10) ◽  
pp. 12642-12651
Author(s):  
Emily J. Hartzell ◽  
Rachel M. Lieser ◽  
Millicent O. Sullivan ◽  
Wilfred Chen
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Virus Like Particle ◽  
B Virus

scholarly journals Yield Optimisation of Hepatitis B Virus Core Particles in E. coli Expression System for Drug Delivery Applications

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Izzat Fahimuddin Bin Mohamed Suffian ◽  
Mitla Garcia-Maya ◽  
Paul Brown ◽  
Tam Bui ◽  
Yuya Nishimura ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Expression System ◽  
E Coli ◽  
Virus Core ◽  
B Virus ◽  
Drug Delivery Applications ◽  
Core Particles

scholarly journals Advances in Nanoparticle Drug Delivery Systems for Anti-Hepatitis B Virus Therapy: A Narrative Review

2021 ◽  
Vol 22 (20) ◽  
pp. 11227
Author(s):  
Jing Miao ◽  
Peng Gao ◽  
Qian Li ◽  
Kaifeng He ◽  
Liwen Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Drug Targets ◽  
Drug Delivery Systems ◽  
Relevant Literature ◽  
Viral Disease ◽  
Delivery Systems ◽  
B Virus ◽  
Nanoparticle Drug Delivery

Chronic hepatitis B (CHB) is an infectious viral disease that is prevalent worldwide. Traditional nucleoside analogues, as well as the novel drug targets against hepatitis B virus (HBV), are associated with certain critical factors that influence the curative effect, such as biological stability and safety, effective drug delivery, and controlled release. Nanoparticle drug delivery systems have significant advantages and have provided a basis for the development of anti-HBV strategies. In this review, we aim to review the advances in nanoparticle drug delivery systems for anti-hepatitis B virus therapy by summarizing the relevant literature. First, we focus on the characteristics of nanoparticle drug delivery systems for anti-HBV therapy. Second, we discuss the nanoparticle delivery systems for anti-HBV nucleoside drugs, gene-based drugs, and vaccines. Lastly, we provide an overview of the prospects for nanoparticle-based anti-HBV agents.

scholarly journals Chemo-Enzymatic Synthesis of Glycolyl-Ester-Linked Taxol-Monosaccharide Conjugate and Its Drug Delivery System Using Hepatitis B Virus Envelope L Bio-Nanocapsules

2012 ◽  
Vol 5 ◽  
pp. BCI.S9824
Author(s):  
Kei Shimoda ◽  
Manabu Hamada ◽  
Masaharu Seno ◽  
Tadakatsu Mandai ◽  
Hiroki Hamada
Keyword(s):  
Hepatocellular Carcinoma ◽  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Drug Delivery System ◽  
Delivery System ◽  
Enzymatic Synthesis ◽  
Water Solubility ◽  
Virus Envelope ◽  
B Virus

Chemo-enzymatic synthesis of glycolyl-ester-linked taxol-glucose conjugate, ie, 7-glycolyltaxol 2′- O-α-D-glucoside, was achieved by using α-glucosidase as a biocatalyst. The water-solubility of 7-glycolyltaxol 2′- O-α-D-glucoside (21 μM) was 53 fold higher than that of taxol. The hepatitis B virus envelope L particles (bio-nanocapsules) are effective for delivering 7-glycolyltaxol 2′- O-α-D-glucoside to human hepatocellular carcinoma NuE cells.

A hepatitis B virus-derived human hepatic cell-specific heparin-binding peptide: identification and application to a drug delivery system

2019 ◽  
Vol 7 (1) ◽  
pp. 322-335 ◽  
Author(s):  
Qiushi Liu ◽  
Masaharu Somiya ◽  
Masumi Iijima ◽  
Kenji Tatematsu ◽  
Shun'ichi Kuroda
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Peptide Identification ◽  
Binding Activity ◽  
Hepatic Cell ◽  
Heparin Binding ◽  
Hepatic Drug ◽  
System P ◽  
B Virus

Hepatitis B virus-mimicking nanoparticles containing doxorubicin for specific human hepatic drug delivery by heparin-binding activity.

scholarly journals Application of hepatitis B virus-like particles to drug delivery vehicle.

2020 ◽  
Vol 93 (0) ◽  
pp. 2-P-249
Author(s):  
Chiho Sakai ◽  
Hirohumi Ookawa ◽  
Kouhei Hosokawa ◽  
Tadashi Watanabe ◽  
Keiji Ueda ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Delivery Vehicle ◽  
Virus Like Particles ◽  
Drug Delivery Vehicle ◽  
B Virus

Novel Tissue and Cell Type-specific Gene / Drug Delivery System Using Surface Engineered Hepatitis B Virus Nano-particles

2004 ◽  
Vol 4 (2) ◽  
pp. 163-167 ◽  
Author(s):  
Tadanori Yamada ◽  
Masakazu Ueda ◽  
Masaharu Seno ◽  
Akihiko Kondo ◽  
Katsuyuki Tanizawa ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Drug Delivery System ◽  
Delivery System ◽  
Nano Particles ◽  
Specific Gene ◽  
Cell Type ◽  
B Virus ◽  
Cell Type Specific

Precore hepatitis B virus carrying lamivudine resistant mutations are not associated with decreassed replication fitness and are sensitive to adefovir

2001 ◽  
Vol 120 (5) ◽  
pp. A64-A64
Author(s):  
R CHEN ◽  
P DESMOND ◽  
W DELANEY ◽  
D COLLEDGE ◽  
R EDWARDS ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
B Virus ◽  
Replication Fitness
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