scholarly journals A Zynq-Based Robotic System for Treatment of Contagious Diseases in Hospital Isolated Environment

Technologies ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 28
Author(s):  
Christos Paparizos ◽  
Nikolaos Tsafas ◽  
Michael Birbas
Keyword(s):  
Assisted Living ◽  
Low Cost ◽  
Rapid Evolution ◽  
Integrated System ◽  
Leap Motion ◽  
Robot System ◽  
Contagious Diseases ◽  
Trained Personnel ◽  
On Chip ◽  
Novel Coronavirus

The rapid evolution of smart assisted living operations in combination with the blooming of commercial robots calls for the use of robotic based systems. Specifically, certain circumstances such as the handling of critical, contagious virus outbreaks like the recent novel Coronavirus epidemic can be benefited by an assisting mobile robot system controlled remotely, complementing measures like the isolation of patients from medical stuff. Within this context, the robotic-based solution to be employed needs to be easy to deploy, able to manufacture with low cost, and able to operate with ease by non-trained personnel. Also, to address the needs of existing hospitals, traditional or smart ones, as well as the temporary risk management facilities in, for example, quarantined cities, ease of integration in terms of size and infrastructure requirements is a must. In this work, the design and implementation of a robotic chassis bearing an arm manipulator is presented, addressing all these needs efficiently. Special attention has been given to the ease of teleoperation with minimal need for equipment and expertise, utilizing a Leap Motion virtual reality sensor which outweighs Microsoft’s Kinect capabilities. Furthermore, a reconfigurable hardware and software integrated system has been used to control the communication, algorithm processing and motion control utilizing a Xilinx Zynq system on chip (SoC).

scholarly journals A 5 V-to-3.3 V CMOS Linear Regulator with Three-Output Temperature-Independent Reference Voltages

2016 ◽  
Vol 2016 ◽  
pp. 1-7
Author(s):  
San-Fu Wang
Keyword(s):  
Output Voltage ◽  
Low Cost ◽  
Integrated System ◽  
Reference Voltage ◽  
Cmos Transistors ◽  
Power Supply Rejection Ratio ◽  
Linear Regulator ◽  
Voltage Variation ◽  
On Chip ◽  
Isolation Performance

This paper presents a 5 V-to-3.3 V linear regulator circuit, which uses 3.3 V CMOS transistors to replace the 5 V CMOS transistors. Thus, the complexity of the manufacturing semiconductor process can be improved. The proposed linear regulator is implemented by cascode architecture, which requires three different reference voltages as the bias voltages of its circuit. Thus, the three-output temperature-independent reference voltage circuit is proposed, which provides three accurate reference voltages simultaneously. The three-output temperature-independent reference voltages also can be used in other circuits of the chip. By using the proposed temperature-independent reference voltages, the proposed linear regulator can provide an accurate output voltage, and it is suitable for low cost, small size, and highly integrated system-on-chip (SoC) applications. Moreover, the proposed linear regulator uses the cascode technique, which improves both the gain performance and the isolation performance. Therefore, the proposed linear regulator has a good performance in reference voltage to output voltage isolation. The voltage variation of the linear regulator is less than 2.153% in the temperature range of −40°C–120°C, and the power supply rejection ratio (PSRR) is less than −42.8 dB at 60 Hz. The regulator can support 0~200 mA output current. The core area is less than 0.16 mm2.

scholarly journals Design and Manufacturing of a Disposable, Cyclo-Olefin Copolymer, Microfluidic Device for a Biosensor †

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1178 ◽  
Author(s):  
Jorge Prada ◽  
Christina Cordes ◽  
Carsten Harms ◽  
Walter Lang
Keyword(s):  
Microfluidic Device ◽  
Heating Temperature ◽  
Low Cost ◽  
Reaction Chamber ◽  
Microfluidic System ◽  
Heating Process ◽  
Design And Manufacturing ◽  
On Chip ◽  
Working Parameters ◽  
Auto Fluorescence

This contribution outlines the design and manufacturing of a microfluidic device implemented as a biosensor for retrieval and detection of bacteria RNA. The device is fully made of Cyclo-Olefin Copolymer (COC), which features low auto-fluorescence, biocompatibility and manufacturability by hot-embossing. The RNA retrieval was carried on after bacteria heat-lysis by an on-chip micro-heater, whose function was characterized at different working parameters. Carbon resistive temperature sensors were tested, characterized and printed on the biochip sealing film to monitor the heating process. Off-chip and on-chip processed RNA were hybridized with capture probes on the reaction chamber surface and identification was achieved by detection of fluorescence tags. The application of the mentioned techniques and materials proved to allow the development of low-cost, disposable albeit multi-functional microfluidic system, performing heating, temperature sensing and chemical reaction processes in the same device. By proving its effectiveness, this device contributes a reference to show the integration potential of fully thermoplastic devices in biosensor systems.

scholarly journals Genetic Variation and Evolution of the 2019 Novel Coronavirus

2021 ◽  
pp. 1-13
Author(s):  
Salvatore Dimonte ◽  
Muhammed Babakir-Mina ◽  
Taib Hama-Soor ◽  
Salar Ali
Keyword(s):  
Amino Acid ◽  
Receptor Binding ◽  
Rapid Evolution ◽  
Single Amino Acid ◽  
Angiotensin Converting Enzyme 2 ◽  
New Type ◽  
Amino Acid Mutations ◽  
Host Infection ◽  
Human Coronaviruses ◽  
Novel Coronavirus

<b><i>Introduction:</i></b> SARS-CoV-2 is a new type of coronavirus causing a pandemic severe acute respiratory syndrome (SARS-2). Coronaviruses are very diverting genetically and mutate so often periodically. The natural selection of viral mutations may cause host infection selectivity and infectivity. <b><i>Methods:</i></b> This study was aimed to indicate the diversity between human and animal coronaviruses through finding the rate of mutation in each of the spike, nucleocapsid, envelope, and membrane proteins. <b><i>Results:</i></b> The mutation rate is abundant in all 4 structural proteins. The most number of statistically significant amino acid mutations were found in spike receptor-binding domain (RBD) which may be because it is responsible for a corresponding receptor binding in a broad range of hosts and host selectivity to infect. Among 17 previously known amino acids which are important for binding of spike to angiotensin-converting enzyme 2 (ACE2) receptor, all of them are conservative among human coronaviruses, but only 3 of them significantly are mutated in animal coronaviruses. A single amino acid aspartate-454, that causes dissociation of the RBD of the spike and ACE2, and F486 which gives the strength of binding with ACE2 remain intact in all coronaviruses. <b><i>Discussion/Conclusion:</i></b> Observations of this study provided evidence of the genetic diversity and rapid evolution of SARS-CoV-2 as well as other human and animal coronaviruses.

scholarly journals Indoor Environmental Quality in Dwellings and Lifestyle Behaviors during the COVID-19 Pandemic: Russian Perspective

2021 ◽  
Vol 18 (11) ◽  
pp. 5975
Author(s):  
Vladimir Reshetnikov ◽  
Oleg Mitrokhin ◽  
Elena Belova ◽  
Victor Mikhailovsky ◽  
Maria Mikerova ◽  
...  
Keyword(s):  
Public Health ◽  
Medical Students ◽  
Environmental Quality ◽  
Indoor Environmental Quality ◽  
Lifestyle Behaviors ◽  
Contagious Diseases ◽  
Health Authorities ◽  
Public Health Authorities ◽  
Isolation Index ◽  
Novel Coronavirus

The novel coronavirus (COVID-19) outbreak is a public health emergency of international concern, and as a response, public health authorities started enforcing preventive measures like self-isolation and social distancing. The enforcement of isolation has consequences that may affect the lifestyle-related behavior of the general population. Quarantine encompasses a range of strategies that can be used to detain, isolate, or conditionally release individuals or populations infected or exposed to contagious diseases and should be tailored to circumstances. Interestingly, medical students may represent an example of how the COVID-19 pandemic can form new habits and change lifestyle behaviors. We conducted a web-based survey to assess changes in lifestyle-related behavior of self-isolated medical students during the COVID-19 pandemic. Then we analyzed the sanitary-hygienic regulations of the Russian Federation to determine the requirements for healthy buildings. Results showed that during the pandemic, the enforcement of isolation affects medical students’ lifestyle-related behavior and accompanies an increase in non-communicable diseases (NCDs). Indoor environmental quality (IEQ) and healthy buildings are cutting-edge factors in preventing COVID-19 and NCDs. The Russian sanitary-hygienic regulations support improving this factor with suitable requirements for ventilation, sewage, waste management, and disinfection. Herein, assessing isolation is possible through the hygienic self-isolation index.

On-Chip Fabrication of None-Dead-Volume Microtips for ESI-MS Applications

2007 ◽  
Vol 121-123 ◽  
pp. 611-614
Author(s):  
Che Hsin Lin ◽  
Jen Taie Shiea ◽  
Yen Lieng Lin
Keyword(s):  
Surface Tension ◽  
Low Cost ◽  
Microfluidic Channel ◽  
Dead Volume ◽  
Esi Ms ◽  
Rapid Fabrication ◽  
Chip Fabrication ◽  
Novel Method ◽  
On Chip ◽  
Highly Uniform

This paper proposes a novel method to on-chip fabricate a none-dead-volume microtip for ESI-MS applications. The microfluidic chip and ESI tip are fabricated in low-cost plastic based materials using a simple and rapid fabrication process. A constant-speed-pulling method is developed to fabricate the ESI tip by pulling mixed PMMA glue using a 30-μm stainless wire through the pre-formed microfluidic channel. The equilibrium of surface tension of PMMA glue will result in a sharp tip after curing. A highly uniform micro-tip can be formed directly at the outlet of the microfluidic channel with minimum dead-volume zone. Detection of caffeine, myoglobin, lysozyme and cytochrome C biosamples confirms the microchip device can be used for high resolution ESI-MS applications.

Fully integrated system-on-chip for pixel-based 3D depth and scene mapping

2012 ◽  
Author(s):  
Martin Popp ◽  
Beat De Coi ◽  
Markus Thalmann ◽  
Radoslav Gancarz ◽  
Pascal Ferrat ◽  
...  
Keyword(s):  
System On Chip ◽  
Integrated System ◽  
Fully Integrated ◽  
On Chip

Optical MEMS platform for low-cost on-chip integration of planar light circuits and optical switching

2004 ◽  
Author(s):  
Kristine A. German ◽  
Joel Kubby ◽  
Jingkuang Chen ◽  
James Diehl ◽  
Kathleen Feinberg ◽  
...  
Keyword(s):  
Optical Switching ◽  
Low Cost ◽  
Optical Mems ◽  
On Chip

A Novel Approach With Bayesian Networks to Multi-Robot Task Allocation in Dynamic Environments

2021 ◽  
Author(s):  
Ching-Wei Chuang ◽  
Harry H. Cheng
Keyword(s):  
Bayesian Networks ◽  
Task Allocation ◽  
Low Cost ◽  
Dynamic Environments ◽  
Modern World ◽  
Robot System ◽  
Novel Approach ◽  
Robot Systems ◽  
Robot Task ◽  
Multi Robot

Abstract In the modern world, building an autonomous multi-robot system is essential to coordinate and control robots to help humans because using several low-cost robots becomes more robust and efficient than using one expensive, powerful robot to execute tasks to achieve the overall goal of a mission. One research area, multi-robot task allocation (MRTA), becomes substantial in a multi-robot system. Assigning suitable tasks to suitable robots is crucial in coordination, which may directly influence the result of a mission. In the past few decades, although numerous researchers have addressed various algorithms or approaches to solve MRTA problems in different multi-robot systems, it is still difficult to overcome certain challenges, such as dynamic environments, changeable task information, miscellaneous robot abilities, the dynamic condition of a robot, or uncertainties from sensors or actuators. In this paper, we propose a novel approach to handle MRTA problems with Bayesian Networks (BNs) under these challenging circumstances. Our experiments exhibit that the proposed approach may effectively solve real problems in a search-and-rescue mission in centralized, decentralized, and distributed multi-robot systems with real, low-cost robots in dynamic environments. In the future, we will demonstrate that our approach is trainable and can be utilized in a large-scale, complicated environment. Researchers might be able to apply our approach to other applications to explore its extensibility.

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