scholarly journals A Tunable Freeform-Segmented Reflector in a Microfluidic System for Conventional and Surface-Enhanced Raman Spectroscopy

Sensors ◽  
2020 ◽  
Vol 20 (5) ◽  
pp. 1250 ◽  
Author(s):  
Qing Liu ◽  
Michael Stenbæk Schmidt ◽  
Hugo Thienpont ◽  
Heidi Ottevaere
Keyword(s):  
Raman Scattering ◽  
Microfluidic Chip ◽  
Numerical Approach ◽  
Surface Enhanced Raman Spectroscopy ◽  
Potassium Nitrate ◽  
Microfluidic System ◽  
Diamond Turning ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Nitrate Solutions

We present a freeform-segmented reflector-based microfluidic system for conventional Raman and Surface-Enhanced Raman Scattering (SERS) analysis. The segmented reflector is directly designed by a numerical approach. The polymer-based Raman system strongly suppresses the undesirable background because it enables confocal detection of Raman scattering through the combination of a freeform reflector and a microfluidic chip. We perform systematic simulations using non-sequential ray tracing with the Henyey-Greenstein model to assess the Raman scattering behavior of the substance under test. We fabricate the freeform reflector and the microfluidic chip by means of ultra-precision diamond turning and laser cutting respectively. We demonstrate the confocal behavior by measuring the Raman spectrum of ethanol. Besides, we calibrate the setup by performing Raman measurements on urea and potassium nitrate solutions with different concentrations. The detection limit of our microfluidic system is approximately 20 mM according to the experiment. Finally, we implement a SERS microfluidic chip and discriminate 100 µM urea and potassium nitrate solutions.

A Reproducible Surface-Enhanced Raman Spectroscopy Approach. Online SERS Measurements in a Segmented Microfluidic System

2007 ◽  
Vol 79 (4) ◽  
pp. 1542-1547 ◽  
Author(s):  
Katrin R. Strehle ◽  
Dana Cialla ◽  
Petra Rösch ◽  
Thomas Henkel ◽  
Michael Köhler ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Microfluidic System ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

scholarly journals Asphaltene detection using surface enhanced Raman scattering (SERS)

2015 ◽  
Vol 51 (33) ◽  
pp. 7152-7155 ◽  
Author(s):  
O. O. Alabi ◽  
A. N. F. Edilbi ◽  
C. Brolly ◽  
D. Muirhead ◽  
J. Parnell ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced Raman Spectroscopy ◽  
Gold Substrate ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Surface enhanced Raman spectroscopy using a gold substrate and excitation at 514 nm can detect sub parts per million quantities of asphaltene and thereby petroleum.

Dynamic Preconcentration of Gold Nanoparticles for Surface-Enhanced Raman Scattering in a Microfluidic System

Small ◽  
2011 ◽  
Vol 8 (3) ◽  
pp. 378-383 ◽  
Author(s):  
Kwang Bok Kim ◽  
Ji-Hyung Han ◽  
Hyoungseon Choi ◽  
Hee Chan Kim ◽  
Taek Dong Chung
Keyword(s):  
Gold Nanoparticles ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Microfluidic System ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Uptake of silver nanoparticles by DHA-treated cancer cells examined by surface-enhanced Raman spectroscopy in a microfluidic chip

Lab on a Chip ◽  
2017 ◽  
Vol 17 (7) ◽  
pp. 1306-1313 ◽  
Author(s):  
Zhimin Zhai ◽  
Fengqiu Zhang ◽  
Xiangyu Chen ◽  
Jie Zhong ◽  
Gang Liu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Cancer Cells ◽  
Microfluidic Chip ◽  
Surface Enhanced Raman Spectroscopy ◽  
Living Cells ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

This paper reports on the synthesis and application of biocompatible and sensitive SERS nanoparticles for the study of uptake of nanoparticles into living cells in a microfluidic chip through surface-enhanced Raman spectroscopy (SERS).

Surface-enhanced Raman scattering on a zigzag microfluidic chip: towards high-sensitivity detection of As(iii) ions

2014 ◽  
Vol 6 (12) ◽  
pp. 4077-4082 ◽  
Author(s):  
Nan Qi ◽  
Bowei Li ◽  
Huiyan You ◽  
Wei Zhang ◽  
Longwen Fu ◽  
...  
Keyword(s):  
Sensitivity Analysis ◽  
Raman Scattering ◽  
Microfluidic Chip ◽  
High Sensitivity ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
High Sensitivity Detection ◽  
Sensitivity Detection

A quantitative sensitivity analysis for trace As(iii) ions was proposed based on the SERS technique on a zigzag microfluidic chip.

Fabrication of lipophilic gold nanoparticles for studying lipids by surface enhanced Raman spectroscopy (SERS)

The Analyst ◽  
2014 ◽  
Vol 139 (13) ◽  
pp. 3352-3355 ◽  
Author(s):  
Michael Driver ◽  
Yue Li ◽  
Jinkai Zheng ◽  
Eric Decker ◽  
David Julian McClements ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced Raman Spectroscopy ◽  
Fabrication Method ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A simple fabrication method for preparing lipophilic gold nanoparticles (AuNPs) suitable for use as substrates in surface-enhanced Raman scattering (SERS) applications of lipids was developed.

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