scholarly journals On-line Monitoring on the Micro-synthesis of α-Phenylethanol by Microfluidic Chip Combined with Surface Enhanced Raman Spectroscopy

2019 ◽  
Vol 77 (3) ◽  
pp. 257
Author(s):  
Jiao Liu ◽  
Hailong Sun ◽  
Lu Yin ◽  
Yaxian Yuan ◽  
Minmin Xu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Microfluidic Chip ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
On Line

Uptake of silver nanoparticles by DHA-treated cancer cells examined by surface-enhanced Raman spectroscopy in a microfluidic chip

Lab on a Chip ◽  
2017 ◽  
Vol 17 (7) ◽  
pp. 1306-1313 ◽  
Author(s):  
Zhimin Zhai ◽  
Fengqiu Zhang ◽  
Xiangyu Chen ◽  
Jie Zhong ◽  
Gang Liu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Cancer Cells ◽  
Microfluidic Chip ◽  
Surface Enhanced Raman Spectroscopy ◽  
Living Cells ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

This paper reports on the synthesis and application of biocompatible and sensitive SERS nanoparticles for the study of uptake of nanoparticles into living cells in a microfluidic chip through surface-enhanced Raman spectroscopy (SERS).

Surface-enhanced Raman spectroscopy on porous silicon membranes decorated with Ag nanoparticles integrated in elastomeric microfluidic chips

RSC Advances ◽  
2016 ◽  
Vol 6 (26) ◽  
pp. 21865-21870 ◽  
Author(s):  
Chiara Novara ◽  
Andrea Lamberti ◽  
Alessandro Chiadò ◽  
Alessandro Virga ◽  
Paola Rivolo ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Porous Silicon ◽  
Microfluidic Chip ◽  
Ag Nanoparticles ◽  
Surface Enhanced Raman Spectroscopy ◽  
Microfluidic Chips ◽  
Label Free ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Silicon Membranes

An elastomeric microfluidic chip integrating SERS active silver-coated porous silicon membranes is developed, which performs label free and calibrated SERS analysis in a multi-analyte configuration.

On-Line Spectroscopic Characterization of Sodium Cyanide with Nanostructured Gold Surface-Enhanced Raman Spectroscopy Substrates

2002 ◽  
Vol 56 (12) ◽  
pp. 1524-1530 ◽  
Author(s):  
Peter M. Tessier ◽  
Steven D. Christesen ◽  
Kate K. Ong ◽  
Eva M. Clemente ◽  
Abraham M. Lenhoff ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sodium Cyanide ◽  
Raman Signal ◽  
Gold Films ◽  
Porous Gold ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
On Line

To implement surface-enhanced Raman spectroscopy as a practical detection method, highly enhancing, stable, and reproducible substrates need to be fabricated in an efficient manner, and their performance in different solution environments should be well characterized. In this work structured porous gold films have been fabricated using colloidal crystals to template gold nanoparticles. These films were integrated into an on-line flow chamber and used to study the effects of pH and other additives on the detection of sodium cyanide. The gold films proved to be highly enhancing and were used to detect cyanide over a wide range of pH values in the concentration range of ∼2 to 200 ppb. The Raman signal intensity could be increased by lowering the pH after the adsorption of cyanide, which was likely due to both a change in the ionization state and a conformational change of the bound molecules. The peak intensity could also be enhanced multifold by treating the substrate with silver nitrate. Cyanide could be removed from the substrates using hydrochloric acid, although this also passivated the structures, and the activity could only be restored partially with tannic acid. These results provide a rational method to optimize the online detection of cyanide in water.

Rapid separation and on-line detection by coupling high performance liquid chromatography with surface-enhanced Raman spectroscopy

RSC Advances ◽  
2015 ◽  
Vol 5 (59) ◽  
pp. 47640-47646 ◽  
Author(s):  
Wei Wang ◽  
Minmin Xu ◽  
Qinghua Guo ◽  
Yaxian Yuan ◽  
Renao Gu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
High Performance ◽  
Surface Enhanced Raman Spectroscopy ◽  
Line Detection ◽  
Food Science ◽  
Rapid Separation ◽  
Complex Samples ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
On Line

The combined HPLC-SERS system was developed to a powerful tool for rapid separation and structural recognition of complex samples in food science and environmental monitoring.

Portable Microfluidic Chip Based Surface-Enhanced Raman Spectroscopy Sensor for Crystal Violet

2014 ◽  
Vol 47 (16) ◽  
pp. 2682-2690 ◽  
Author(s):  
Bingxiang Liu ◽  
Ting Wu ◽  
Xiaohui Yang ◽  
Zhenping Wang ◽  
Yiping Du
Keyword(s):  
Raman Spectroscopy ◽  
Crystal Violet ◽  
Microfluidic Chip ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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