scholarly journals Electrospun Nanofibers for Label-Free Sensor Applications

Sensors ◽  
2019 ◽  
Vol 19 (16) ◽  
pp. 3587 ◽  
Author(s):  
Nahal Aliheidari ◽  
Nojan Aliahmad ◽  
Mangilal Agarwal ◽  
Hamid Dalir
Keyword(s):  
Low Cost ◽  
High Surface ◽  
Volume Ratio ◽  
Electrospun Nanofibers ◽  
Label Free ◽  
Sensor Applications ◽  
Wide Range ◽  
Sensor Properties ◽  
Fundamental Research ◽  
Future Work

Electrospinning is a simple, low-cost and versatile method for fabricating submicron and nano size fibers. Due to their large surface area, high aspect ratio and porous structure, electrospun nanofibers can be employed in wide range of applications. Biomedical, environmental, protective clothing and sensors are just few. The latter has attracted a great deal of attention, because for biosensor application, nanofibers have several advantages over traditional sensors, including a high surface-to-volume ratio and ease of functionalization. This review provides a short overview of several electrospun nanofibers applications, with an emphasis on biosensor applications. With respect to this area, focus is placed on label-free sensors, pertaining to both recent advances and fundamental research. Here, label-free sensor properties of sensitivity, selectivity, and detection are critically evaluated. Current challenges in this area and prospective future work is also discussed.

scholarly journals NANOFIBRAS ELETROFIADAS E SUAS APLICAÇÕES: AVANÇOS NA ÚLTIMA DÉCADA

Química Nova ◽  
2021 ◽  
Author(s):  
Luiza Mercante ◽  
Rafaela Andre ◽  
Juliana Macedo ◽  
Adriana Pavinatto ◽  
Daniel Correa
Keyword(s):  
Mechanical Performance ◽  
Low Cost ◽  
High Surface ◽  
High Surface Area ◽  
Volume Ratio ◽  
Electrospun Nanofibers ◽  
Electrospinning Technique ◽  
Structures And Properties ◽  
Wide Range ◽  
Simple Processing

ELECTROSPUN NANOFIBERS AND THEIR APPLICATIONS: ADVANCES IN THE LAST DECADE. In recent years there has been an increasing interest in the development of nanomaterials with improved properties compared to their counterparts at the micro- and macroscopic scale. In this context, nanofibers obtained by electrospinning technique are highly attractive due to the unique combination of high surface area/volume ratio, porosity, flexibility, mechanical performance, simple processing and relatively low cost. In addition, the possibility to buildup nanofibers with different compositions, structures and properties allows the design of nanostructures for a wide range of applications. In this review, we will discuss the advances of the last decade in the use of the electrospinning to obtain nanofibers with different compositions and morphologies for varied applications. Specifically, we are interested in providing an overview of the state of the art in relation to the application of nanofibers in different areas, including healthcare, environment, sensing and energy. Finally, we will discuss the real perspective in terms of industrial application and future trends that have been pursued to improve the performance of electrospun nanofibers. This review will help researchers to understand the evolution and challenges of the area and will also stimulate even more interest in the development of new devices based on electrospun nanofibers

scholarly journals Research Progress on the Applications of Electrospun Nanofibers in Catalysis

Catalysts ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 9
Author(s):  
M. Olga Guerrero-Pérez
Keyword(s):  
Low Cost ◽  
High Surface ◽  
High Surface Area ◽  
Volume Ratio ◽  
Electrospun Nanofibers ◽  
Internal Diffusion ◽  
Research Progress ◽  
Bibliographic Analysis ◽  
Low Resistance ◽  
Electro Catalysis

During the last two decades, electrospinning has become a very popular technique for the fabrication of nanofibers due to its low cost and simple handling. Nanofiber materials have found utilization in many areas such as medicine, sensors, batteries, etc. In catalysis, these materials also present important advantages, since they present a low resistance to internal diffusion and a high surface area to volume ratio. These advantages are mainly due to the diameter–length proportion. A bibliographic analysis on the applications of electrospun nanofibers in catalysis shows that there are two important groups of catalysts that are being investigated, based on TiO2 and in carbon materials. The main applications found are in photo- and in electro-catalysis. The present study contributes by reviewing these catalytic applications of electrospun nanofibers and demonstrating that they are promising materials as catalysts, underlining some works to prove the advantages and possibilities that these materials have as catalysts. On one hand, the possibilities of synthesis are almost infinite, since with coaxial electrospinning quite complex nanofibers with different layers can be prepared. On the other hand, the diameter and other properties can be controlled by monitoring the applied voltage and other parameters during the synthesis, being quite reproducible procedures. The main advantages of these materials can be grouped in two: one related to their morphology, as has been commented, relative to their low resistance and internal diffusion, that is, their fluidynamic behavior in the reactor; the second group involves advantages related to the fact that the active phases can be nanoscaled and dispersed, improving the activity and selectivity in comparison with conventional catalytic materials with the same chemical composition.

scholarly journals Applications of electrospun nanofibers in the biomedical field

SURG Journal ◽  
2012 ◽  
Vol 5 (2) ◽  
pp. 63-73 ◽  
Author(s):  
Nishath Khan
Keyword(s):  
High Surface ◽  
High Surface Area ◽  
Volume Ratio ◽  
Electrospun Nanofibers ◽  
Ease Of Use ◽  
The Past ◽  
Wide Range ◽  
Novel Method ◽  
Biomedical Field ◽  
Highly Porous

Electrospinning is a technology that has been widely used as a novel method for the generation of nano scale fibres. Electrospun fibres are used in a wide range of applications from electronics to textile. The viability and popularity of this technology can be evidenced by its ease of use and the simplicity of the science behind building the electrospinning machine. The generated fibres have a high surface area- to- volume ratio, the fibrous mats are highly porous and display excellent mechanical properties when compared to other materials of the same scale. In the past decade, this technology has taken off with the use of biocompatible and biodegradable polymers. This review is a summary of the different ways in which electrospinning can be used in the biomedical field. This article analyzes the recent advances of this technology in tissue engineering, drug delivery and in enzyme immobilisation, which once again showcases the versatility of the electrospinning procedure.

scholarly journals Bio-nano interactions: binding proteins, polysaccharides, lipids and nucleic acids onto magnetic nanoparticles

2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Lucía Abarca-Cabrera ◽  
Paula Fraga-García ◽  
Sonja Berensmeier
Keyword(s):  
Nucleic Acids ◽  
Driving Forces ◽  
Structural Characteristics ◽  
Low Cost ◽  
High Surface ◽  
Experimental Studies ◽  
Volume Ratio ◽  
Functionalized Surfaces ◽  
Major Interest ◽  
Future Work

AbstractThe major interest in nanoparticles as an application platform for biotechnology arises from their high surface-to-volume ratio. Iron oxide nanoparticles (IONPs) are particularly appealing due to their superparamagnetic behavior, which enables bioseparation using external magnetic fields. In order to design advanced biomaterials, improve binding capacities and develop innovative processing solutions, a thorough understanding of the factors governing organic-inorganic binding in solution is critical but has not yet been achieved, given the wide variety of chemical and physical influences. This paper offers a critical review of experimental studies of the interactions between low cost IONPs (bare iron oxides, silica-coated or easily-functionalized surfaces) and the main groups of biomolecules: proteins, lipids, nucleic acids and carbohydrates. Special attention is devoted to the driving forces and interdependencies responsible of interactions at the solid-liquid interface, to the unique structural characteristics of each biomolecular class, and to environmental conditions influencing adsorption. Furthermore, studies focusing on mixtures, which are still rare, but absolutely necessary to understand the biocorona, are also included. This review concludes with a discussion of future work needed to fill the gaps in knowledge of bio-nano interactions, seeking to improve nanoparticles’ targeting capabilities in complex systems, and to open the door for multipurpose recognition and bioseparation processes.

scholarly journals Electrospun Nanofibers for Sensing and Biosensing Applications—A Review

2021 ◽  
Vol 22 (12) ◽  
pp. 6357
Author(s):  
Kinga Halicka ◽  
Joanna Cabaj
Keyword(s):  
High Surface ◽  
High Surface Area ◽  
Toxic Metal ◽  
Volume Ratio ◽  
Electrospun Nanofibers ◽  
Clinical Diagnostics ◽  
Loading Capacity ◽  
Electrospun Nanofiber ◽  
Sensing Platforms ◽  
Different Types

Sensors and biosensors have found applications in many areas, e.g., in medicine and clinical diagnostics, or in environmental monitoring. To expand this field, nanotechnology has been employed in the construction of sensing platforms. Because of their properties, such as high surface area to volume ratio, nanofibers (NFs) have been studied and used to develop sensors with higher loading capacity, better sensitivity, and faster response time. They also allow to miniaturize designed platforms. One of the most commonly used techniques of the fabrication of NFs is electrospinning. Electrospun NFs can be used in different types of sensors and biosensors. This review presents recent studies concerning electrospun nanofiber-based electrochemical and optical sensing platforms for the detection of various medically and environmentally relevant compounds, including glucose, drugs, microorganisms, and toxic metal ions.

scholarly journals A Review on Biosensors and Recent Development of Nanostructured Materials-Enabled Biosensors

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1109
Author(s):  
Varnakavi. Naresh ◽  
Nohyun Lee
Keyword(s):  
High Surface ◽  
Three Dimensional ◽  
Biological Response ◽  
Volume Ratio ◽  
Recent Decade ◽  
Disease Diagnosis ◽  
Electrical Signal ◽  
Detection Sensitivity ◽  
Wide Range ◽  
Color Tunability

A biosensor is an integrated receptor-transducer device, which can convert a biological response into an electrical signal. The design and development of biosensors have taken a center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications, such as health care and disease diagnosis, environmental monitoring, water and food quality monitoring, and drug delivery. The main challenges involved in the biosensor progress are (i) the efficient capturing of biorecognition signals and the transformation of these signals into electrochemical, electrical, optical, gravimetric, or acoustic signals (transduction process), (ii) enhancing transducer performance i.e., increasing sensitivity, shorter response time, reproducibility, and low detection limits even to detect individual molecules, and (iii) miniaturization of the biosensing devices using micro-and nano-fabrication technologies. Those challenges can be met through the integration of sensing technology with nanomaterials, which range from zero- to three-dimensional, possessing a high surface-to-volume ratio, good conductivities, shock-bearing abilities, and color tunability. Nanomaterials (NMs) employed in the fabrication and nanobiosensors include nanoparticles (NPs) (high stability and high carrier capacity), nanowires (NWs) and nanorods (NRs) (capable of high detection sensitivity), carbon nanotubes (CNTs) (large surface area, high electrical and thermal conductivity), and quantum dots (QDs) (color tunability). Furthermore, these nanomaterials can themselves act as transduction elements. This review summarizes the evolution of biosensors, the types of biosensors based on their receptors, transducers, and modern approaches employed in biosensors using nanomaterials such as NPs (e.g., noble metal NPs and metal oxide NPs), NWs, NRs, CNTs, QDs, and dendrimers and their recent advancement in biosensing technology with the expansion of nanotechnology.

Effect of current density on the porous silicon preparation as gas sensors**

2021 ◽  
Vol 30 (1) ◽  
pp. 257-264
Author(s):  
Muna H. Kareem ◽  
Adi M. Abdul Hussein ◽  
Haitham Talib Hussein
Keyword(s):  
Porous Silicon ◽  
Gas Sensors ◽  
Current Density ◽  
Room Temperature ◽  
Low Cost ◽  
High Surface ◽  
Volume Ratio ◽  
Etching Time ◽  
Force Microscopy ◽  
Materials Used

Abstract In this study, porous silicon (PSi) was used to manufacture gas sensors for acetone and ethanol. Samples of PSi were successfully prepared by photoelectrochemical etching and applied as an acetone and ethanol gas sensor at room temperature at various current densities J= 12, 24 and 30 mA/cm2 with an etching time of 10 min and hydrofluoric acid concentration of 40%. Well-ordered n-type PSi (100) was carefully studied for its chemical composition, surface structure and bond configuration of the surface via X-ray diffraction, atomic force microscopy, Fourier transform infrared spectroscopy and photoluminescence tests. Results showed that the best sensitivity of PSi was to acetone gas than to ethanol under the same conditions at an etching current density of 30 mA/cm2, reaching about 2.413 at a concentration of 500 parts per million. The PSi layers served as low-cost and high-quality acetone gas sensors. Thus, PSi can be used to replace expensive materials used in gas sensors that function at low temperatures, including room temperature. The material has an exceptionally high surface-to-volume ratio (increasing surface area) and demonstrates ease of fabrication and compatibility with manufacturing processes of silicon microelectronics.

scholarly journals A Review of Carbon Nanotubes-Based Gas Sensors

2009 ◽  
Vol 2009 ◽  
pp. 1-24 ◽  
Author(s):  
Yun Wang ◽  
John T. W. Yeow
Keyword(s):  
Carbon Nanotubes ◽  
Gas Sensors ◽  
Gas Sensing ◽  
Low Cost ◽  
High Surface ◽  
Hollow Structure ◽  
Volume Ratio ◽  
Fast Response ◽  
Sensing Technology ◽  
Structure Of Nanomaterials

Gas sensors have attracted intensive research interest due to the demand of sensitive, fast response, and stable sensors for industry, environmental monitoring, biomedicine, and so forth. The development of nanotechnology has created huge potential to build highly sensitive, low cost, portable sensors with low power consumption. The extremely high surface-to-volume ratio and hollow structure of nanomaterials is ideal for the adsorption of gas molecules. Particularly, the advent of carbon nanotubes (CNTs) has fuelled the inventions of gas sensors that exploit CNTs' unique geometry, morphology, and material properties. Upon exposure to certain gases, the changes in CNTs' properties can be detected by various methods. Therefore, CNTs-based gas sensors and their mechanisms have been widely studied recently. In this paper, a broad but yet in-depth survey of current CNTs-based gas sensing technology is presented. Both experimental works and theoretical simulations are reviewed. The design, fabrication, and the sensing mechanisms of the CNTs-based gas sensors are discussed. The challenges and perspectives of the research are also addressed in this review.

scholarly journals Label-Free Optical Biosensing Using Low-Cost Electrospun Polymeric Nanofibers

Chemosensors ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 119
Author(s):  
Paula Martínez-Pérez ◽  
Salvador Ponce-Alcántara ◽  
Nieves Murillo ◽  
Ana Pérez-Márquez ◽  
Jon Maudes ◽  
...  
Keyword(s):  
Real Time ◽  
Large Scale ◽  
High Surface ◽  
Protein A ◽  
Volume Ratio ◽  
Polyamide 6 ◽  
Optical Biosensor ◽  
Label Free ◽  
Electrospinning Technique ◽  
Optical Biosensing

Polymeric nanofiber matrices are promising structures to develop biosensing devices due to their easy and affordable large-scale fabrication and their high surface-to-volume ratio. In this work, the suitability of a polyamide 6 nanofiber matrix for the development of a label-free and real-time Fabry–Pérot cavity-based optical biosensor was studied. For such aim, in-flow biofunctionalization of nanofibers with antibodies, bound through a protein A/G layer, and specific biodetection of 10 µg/mL bovine serum albumin (BSA) were carried out. Both processes were successfully monitored via reflectivity measurements in real-time without labels and their reproducibility was demonstrated when different polymeric nanofiber matrices from the same electrospinning batch were employed as transducers. These results demonstrate not only the suitability of correctly biofunctionalized polyamide 6 nanofiber matrices to be employed for real-time and label-free specific biodetection purposes, but also the potential of electrospinning technique to create affordable and easy-to-fabricate at large scale optical transducers with a reproducible performance.

scholarly journals Continuous tuning of the plasmon resonance frequency of porous gold nanoparticles by mixed oxide layers

2020 ◽  
Vol 27 (6) ◽  
pp. 1583-1588
Author(s):  
Laura Juhász ◽  
Bence Parditka ◽  
Péter Petrik ◽  
Csaba Cserháti ◽  
Zoltán Erdélyi
Keyword(s):  
Gold Nanoparticles ◽  
Resonance Frequency ◽  
Mixed Oxide ◽  
High Surface ◽  
Volume Ratio ◽  
Mixture Ratio ◽  
Optical Extinction ◽  
Oxide Layers ◽  
Porous Gold ◽  
Wide Range

Abstract Porous gold nanoparticles (PGNs) are very popular due to their high surface/volume ratio, moreover they have stronger plasmonic properties than their solid counterparts. These properties make the porous gold nanoparticles very useful for lots of applications, for instance chemical sensors, cancer therapy applications. For applications, however, it is indispensable that the resonance frequency (RF) of a plasmonic structure to be tuneable. In this work we show that the RF can be set in a wide range as desired by coating the PGNs by mixed oxide layers. By changing the composition of the coating layer, that is the mixture ratio, the RF can be shifted practically continuously in a wide range determined by the refractive index of the used oxides. As a demonstration, PGNs were coated with mixed alumina-titania oxide layers (5–7 nm) using plasma-enhanced atomic layer deposition method. The oxide layer, beside as a tuning tool, also stabilises the structure of the PGNs when are exposed to elevated temperature. This is shown by the influence of the temperature (from $$350\, ^{\circ }\hbox {C}$$ 350 ∘ C up to $$900\, ^{\circ }\hbox {C}$$ 900 ∘ C ) on the morphology, and as a consequence the optical extinction spectra, of the oxide coated PGNs.

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