scholarly journals 3D Printed Sensors for Biomedical Applications: A Review

Sensors ◽  
2019 ◽  
Vol 19 (7) ◽  
pp. 1706 ◽  
Author(s):  
Tao Han ◽  
Sudip Kundu ◽  
Anindya Nag ◽  
Yongzhao Xu
Keyword(s):  
3D Printing ◽  
Biomedical Applications ◽  
Market Survey ◽  
Healthcare Applications ◽  
Biomedical Sensing ◽  
Printed Sensors ◽  
3D Printed ◽  
The Individual ◽  
Work Done ◽  
Printing Techniques

This paper showcases a substantial review on some of the significant work done on 3D printing of sensors for biomedical applications. The importance of 3D printing techniques has bloomed in the sensing world due to their essential advantages of quick fabrication, easy accessibility, processing of varied materials and sustainability. Along with the introduction of the necessity and influence of 3D printing techniques for the fabrication of sensors for different healthcare applications, the paper explains the individual methodologies used to develop sensing prototypes. Six different 3D printing techniques have been explained in the manuscript, followed by drawing a comparison between them in terms of their advantages, disadvantages, materials being processed, resolution, repeatability, accuracy and applications. Finally, a conclusion of the paper is provided with some of the challenges of the current 3D printing techniques about the developed sensing prototypes, their corresponding remedial solutions and a market survey determining the expenditure on 3D printing for biomedical sensing prototypes.

scholarly journals Recent Progress in 3D Printed Mold-Based Sensors

Sensors ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 703 ◽  
Author(s):  
Shan He ◽  
Shilun Feng ◽  
Anindya Nag ◽  
Nasrin Afsarimanesh ◽  
Tao Han ◽  
...  
Keyword(s):  
3D Printing ◽  
Recent Progress ◽  
Raw Materials ◽  
Electronic Waste ◽  
Market Survey ◽  
Sensors And Actuators ◽  
Significant Research ◽  
Printed Sensors ◽  
3D Printed ◽  
Different Parts

The paper presents a review of some of the significant research done on 3D printed mold-based sensors performed in recent times. The utilization of the master molds to fabricate the different parts of the sensing prototypes have been followed for quite some time due to certain distinct advantages. Some of them are easy template preparation, easy customization of the developed products, quick fabrication, and minimized electronic waste. The paper explains the different kinds of sensors and actuators that have been developed using this technique, based on their varied structural dimensions, processed raw materials, designing, and product testing. These differences in the attributes were based on their individualistic application. Furthermore, some of the challenges related to the existing sensors and their possible respective solutions have also been mentioned in the paper. Finally, a market survey has been provided, stating the estimated increase in the annual growth of 3D printed sensors. It also states the type of 3D printing that has been preferred over the years, along with the range of sensors, and their related applications.

scholarly journals 3D-Printed Microfluidics and Potential Biomedical Applications

2021 ◽  
Vol 3 ◽  
Author(s):  
Priyanka Prabhakar ◽  
Raj Kumar Sen ◽  
Neeraj Dwivedi ◽  
Raju Khan ◽  
Pratima R. Solanki ◽  
...  
Keyword(s):  
3D Printing ◽  
Biomedical Applications ◽  
Chemical Properties ◽  
Microfluidic Devices ◽  
Microfluidic Chips ◽  
3D Printers ◽  
Broad Variety ◽  
3D Printed ◽  
Diagnostic Technologies ◽  
Printing Techniques

3D printing is a smart additive manufacturing technique that allows the engineering of biomedical devices that are usually difficult to design using conventional methodologies such as machining or molding. Nowadays, 3D-printed microfluidics has gained enormous attention due to their various advantages including fast production, cost-effectiveness, and accurate designing of a range of products even geometrically complex devices. In this review, we focused on the recent significant findings in the field of 3D-printed microfluidic devices for biomedical applications. 3D printers are used as fabrication tools for a broad variety of systems for a range of applications like diagnostic microfluidic chips to detect different analytes, for example, glucose, lactate, and glutamate and the biomarkers related to different clinically relevant diseases, for example, malaria, prostate cancer, and breast cancer. 3D printers can print various materials (inorganic and polymers) with varying density, strength, and chemical properties that provide users with a broad variety of strategic options. In this article, we have discussed potential 3D printing techniques for the fabrication of microfluidic devices that are suitable for biomedical applications. Emerging diagnostic technologies using 3D printing as a method for integrating living cells or biomaterials into 3D printing are also reviewed.

scholarly journals 3D-Printing of Drug-Eluting Implants: An Overview of the Current Developments Described in the Literature

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 4066
Author(s):  
Vanessa Domsta ◽  
Anne Seidlitz
Keyword(s):  
3D Printing ◽  
Complex Geometry ◽  
Individualized Medicine ◽  
Surgical Meshes ◽  
Drug Eluting ◽  
3D Printed ◽  
Different Shapes ◽  
The Individual ◽  
Application Fields ◽  
Printing Techniques

The usage of 3D-printing for drug-eluting implants combines the advantages of a targeted local drug therapy over longer periods of time at the precise location of the disease with a manufacturing technique that easily allows modifications of the implant shape to comply with the individual needs of each patient. Research until now has been focused on several aspects of this topic such as 3D-printing with different materials or printing techniques to achieve implants with different shapes, mechanical properties or release profiles. This review is intended to provide an overview of the developments currently described in the literature. The topic is very multifaceted and several of the investigated aspects are not related to just one type of application. Consequently, this overview deals with the topic of 3D-printed drug-eluting implants in the application fields of stents and catheters, gynecological devices, devices for bone treatment and surgical screws, antitumoral devices and surgical meshes, as well as other devices with either simple or complex geometry. Overall, the current findings highlight the great potential of the manufacturing of drug-eluting implants via 3D-printing technology for advanced individualized medicine despite remaining challenges such as the regulatory approval of individualized implants.

scholarly journals Off-Axis Diffractive Optics for Compact Terahertz Detection Setup

2020 ◽  
Vol 10 (23) ◽  
pp. 8594
Author(s):  
Paweł Komorowski ◽  
Mateusz Surma ◽  
Michał Walczakowski ◽  
Przemysław Zagrajek ◽  
Agnieszka Siemion
Keyword(s):  
3D Printing ◽  
Small Volume ◽  
Optical Element ◽  
Structure Design ◽  
Thz Radiation ◽  
Direct Printing ◽  
Terahertz Detection ◽  
3D Printed ◽  
Printing Techniques ◽  
Optical Structure

Medical and many other applications require small-volume setups enabling terahertz imaging. Therefore, we aim to develop a device for the in-reflection examination of the samples. Thus, in this article, we focus on the diffractive elements for efficient redirection and focusing of the THz radiation. A terahertz diffractive optical structure has been designed, optimized, manufactured (using extrusion-based 3D printing) and tested. Two manufacturing methods have been used—direct printing of the structures from PA12, and casting of the paraffin structures out of 3D-printed molds. Also, the limitations of the off-axis focusing have been discussed. To increase the efficiency, an iterative algorithm has been proposed that optimizes off-axis structures to focus the radiation into small focal spots located far from the optical axis, at an angle of more than 30 degrees. Moreover, the application of higher-order kinoform structure design allowed the maintaining of the smallest details of the manufactured optical element, using 3D printing techniques.

scholarly journals 3D Printed Chromophoric Sensors

Chemosensors ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 317
Author(s):  
Zachary Brounstein ◽  
Jarrod Ronquillo ◽  
Andrea Labouriau
Keyword(s):  
Thermal Stability ◽  
3D Printing ◽  
Material Properties ◽  
Chemical Structure ◽  
Elevated Temperatures ◽  
Advanced Manufacturing ◽  
Color Changes ◽  
Printed Sensors ◽  
3D Printed ◽  
Manufacturing Techniques

Eight chromophoric indicators are incorporated into Sylgard 184 to develop sensors that are fabricated either by traditional methods such as casting or by more advanced manufacturing techniques such as 3D printing. The sensors exhibit specific color changes when exposed to acidic species, basic species, or elevated temperatures. Additionally, material properties are investigated to assess the chemical structure, Shore A Hardness, and thermal stability. Comparisons between the casted and 3D printed sensors show that the sensing devices fabricated with the advanced manufacturing technique are more efficient because the color changes are more easily detected.

scholarly journals Approaches of combining a 3D-printed elastic structure and a hydrogel to create models for plant-inspired actuators

MRS Advances ◽  
2021 ◽  
Author(s):  
Nadia Rodriguez ◽  
Anil K. Bastola ◽  
Marc Behl ◽  
Patricia Soffiatti ◽  
Nick P. Rowe ◽  
...  
Keyword(s):  
3D Printing ◽  
Functional Traits ◽  
Active Component ◽  
Preliminary Investigation ◽  
Polymeric Materials ◽  
Southeastern Brazil ◽  
Passive Component ◽  
Material System ◽  
3D Printed ◽  
Printing Techniques

Abstract Inspired by the interesting functional traits of a climbing cactus, Selenicereus setaceus, found in the forest formations of Southeastern Brazil, we formulated a hypothesis that we can directly learn from the plants to develop multi-functional artificial systems by means of a multi-disciplinary approach. In this context, our approach is to take advantage of 3D-printing techniques and shape-memory hydrogels synergistically to mimic the functional traits of the cactus. This work reports on the preliminary investigation of cactus-inspired artificial systems. First, we 3D-printed soft polymeric materials and characterized them, which defines the structure and is a passive component of a multi-material system. Second, different hydrogels were synthesized and characterized, which is an active component of a multi-material system. Finally, we investigated how the hydrogel can be integrated into the 3D-printed constructs to develop artificial functional systems. Graphic abstract

scholarly journals Beam Scanning Capabilities of a 3D-Printed Perforated Dielectric Transmitarray

Electronics ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 379 ◽  
Author(s):  
Andrea Massaccesi ◽  
Gianluca Dassano ◽  
Paola Pirinoli
Keyword(s):  
3D Printing ◽  
Unit Cell ◽  
Multibeam Antenna ◽  
Beam Scanning ◽  
Additional Advantage ◽  
Ka Band ◽  
Measured Radiation ◽  
3D Printed ◽  
Printing Techniques

In this paper, the design of a beam scanning, 3D-printed dielectric Transmitarray (TA) working in Ka-band is discussed. Thanks to the use of an innovative three-layer dielectric unit-cell that exploits tapered sections to enhance the bandwidth, a 50 × 50 elements transmitarray with improved scanning capabilities and wideband behavior has been designed and experimentally validated. The measured radiation performances over a scanning coverage of ±27 ∘ shown a variation of the gain lower than 2.9 dB and a 1-dB bandwidth in any case higher than 23%. The promising results suggest that the proposed TA technology is a valid alternative to realize a passive multibeam antenna, with the additional advantage that it can be easily manufactured using 3D-printing techniques.

scholarly journals DLP 3D Printing Meets Lignocellulosic Biopolymers: Carboxymethyl Cellulose Inks for 3D Biocompatible Hydrogels

Polymers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 1655 ◽  
Author(s):  
Giuseppe Melilli ◽  
Irene Carmagnola ◽  
Chiara Tonda-Turo ◽  
Fabrizio Pirri ◽  
Gianluca Ciardelli ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Additive Manufacturing ◽  
3D Printing ◽  
Carboxymethyl Cellulose ◽  
Biomedical Applications ◽  
Digital Light Processing ◽  
Chemically Modified ◽  
Significant Step ◽  
3D Printed ◽  
Biomedical Field

The development of new bio-based inks is a stringent request for the expansion of additive manufacturing towards the development of 3D-printed biocompatible hydrogels. Herein, methacrylated carboxymethyl cellulose (M-CMC) is investigated as a bio-based photocurable ink for digital light processing (DLP) 3D printing. CMC is chemically modified using methacrylic anhydride. Successful methacrylation is confirmed by 1H NMR and FTIR spectroscopy. Aqueous formulations based on M-CMC/lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) photoinitiator and M-CMC/Dulbecco’s Modified Eagle Medium (DMEM)/LAP show high photoreactivity upon UV irradiation as confirmed by photorheology and FTIR. The same formulations can be easily 3D-printed through a DLP apparatus to produce 3D shaped hydrogels with excellent swelling ability and mechanical properties. Envisaging the application of the hydrogels in the biomedical field, cytotoxicity is also evaluated. The light-induced printing of cellulose-based hydrogels represents a significant step forward in the production of new DLP inks suitable for biomedical applications.

scholarly journals The Application of 3D-Printing Techniques in the Manufacturing of Cement-Based Construction Products and Experiences Based on the Assessment of Such Products

Buildings ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 144
Author(s):  
Guillermo Sotorrío Ortega ◽  
Javier Alonso Madrid ◽  
Nils O. E. Olsson ◽  
José Antonio Tenorio Ríos
Keyword(s):  
3D Printing ◽  
Construction Industry ◽  
Material Consumption ◽  
Construction Products ◽  
International Projects ◽  
Substantial Progress ◽  
3D Printed ◽  
Materials Used ◽  
Printing Techniques

The construction industry has embraced digitisation and industrialisation in response to the need to increase its productivity, optimise material consumption and improve workmanship. Additive manufacturing (AM), more widely known as 3D printing, has driven substantial progress in these respects in other industries, and a number of national and international projects have helped to introduce the technique to the construction industry. As with other innovative processes not covered by uniform standards, appropriate assessments and testing methodologies to control the quality of the 3D-printed end products, while not obligatory, are advisable. This article shows that regulation is not an obstacle to the use of an innovative product, such as 3D printing, by proposing quality-control tests and an assessment methodology, in the understanding that standardisation ensures the viability of a technology. The information, including the methods and results, is based on the authors’ experiences in the development of three research projects pertaining to 3D printing. This paper also discusses whether the performance of the materials used in 3D printing could be superior to traditional ones.

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