scholarly journals Highly Sensitive Detection of 4-Methylimidazole Using a Terahertz Metamaterial

Sensors ◽  
2018 ◽  
Vol 18 (12) ◽  
pp. 4304 ◽  
Author(s):  
Hee Shin ◽  
Hae Jang ◽  
Gyeongsik Ok
Keyword(s):  
Resonance Frequency ◽  
Detection Method ◽  
Sensitive Detection ◽  
Fdtd Simulation ◽  
Resonator Structure ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Difference Time ◽  
Insight Into ◽  
Good Agreement

In this study, we demonstrated a highly sensitive detection method of 4-methylimidazole (4-MeI), a carcinogenic material, by using a terahertz (THz) metamaterial at a THz region. The THz metamaterials were fabricated with a metal array, using an electric-field-coupled inductor-capacitor (ELC) resonator structure, and a finite-difference time-domain (FDTD) simulation showed good agreement with the experimental results. We measured the THz spectra of the metamaterials to detect the 4-MeI concentrations of 0, 1, 2, 5, 10, 15, and 20 mg/L. The resonance frequency of the metamaterial was shifted by, approximately, 8 GHz and transmittance at the resonance frequency increased to 2 × 10−3, as the concentration was increased, up to 20 mg/L. Our study provides new insight into the application of metamaterials in detecting carcinogens, using a THz technique.

scholarly journals Highly Sensitive Detection of 4-Methylimidazole Using a Terahertz Metamaterial

2018 ◽  
Author(s):  
Hee Jun Shin ◽  
Hae Won Jang ◽  
Gyeongsik Ok
Keyword(s):  
Electric Field ◽  
Resonance Frequency ◽  
Field Enhancement ◽  
Sensitive Detection ◽  
Fdtd Simulation ◽  
Resonator Structure ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
First Time ◽  
Good Agreement

We demonstrate, for the first time, a highly sensitive detection of 4-methylimidazole (4-MeI), a carcinogenic material, by applying an electric field enhancement technique using a terahertz (THz) metamaterial at the THz region. The THz metamaterials were fabricated with a metal array using an electric-field-coupled inductor-capacitor (ELC) resonator structure, and FDTD simulation showed good agreement with experimental results. We measured the THz spectra of the metamaterials to detect 4-MeI concentrations of 0, 1, 2, 5, 10, 15, and 20 mg/L. The resonance frequency of the metamaterial was shifted by approximately 8 GHz and transmittance at the resonance frequency increased to 2 x 10-3 as the concentration was increased, up to 20 mg/L. Our study provides new insight into application of metamaterials to detect carcinogen using a THz technique.

Highly sensitive detection method of retinoblastoma genetic predisposition and biomarkers

2021 ◽  
Author(s):  
Jessica Le Gall ◽  
Catherine Dehainault ◽  
Camille Benoist ◽  
Alexandre Matet ◽  
Livia Lumbroso-Le Rouic ◽  
...  
Keyword(s):  
Genetic Predisposition ◽  
Detection Method ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

SERS-based immunoassay of anti-cyclic citrullinated peptide for early diagnosis of rheumatoid arthritis

RSC Advances ◽  
2014 ◽  
Vol 4 (62) ◽  
pp. 32924-32927 ◽  
Author(s):  
Hyangah Chon ◽  
Sangyeop Lee ◽  
Rui Wang ◽  
So-Young Bang ◽  
Hye-Soon Lee ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Diagnosis ◽  
Detection Method ◽  
Sensitive Detection ◽  
Clinical Tool ◽  
Cyclic Citrullinated Peptide ◽  
Immunoassay Technique ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Citrullinated Peptide

We report a highly sensitive detection method for anti-CCP autoantibodies using a SERS-based magnetic immunosensor. The proposed immunoassay technique is expected to be a new clinical tool for the early diagnosis of rheumatoid arthritis (RA).

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