scholarly journals Coumarin Probe for Selective Detection of Fluoride Ions in Aqueous Solution and Its Bioimaging in Live Cells

Sensors ◽  
2018 ◽  
Vol 18 (7) ◽  
pp. 2042 ◽  
Author(s):  
Kantapat Chansaenpak ◽  
Anyanee Kamkaew ◽  
Oratai Weeranantanapan ◽  
Khomson Suttisintong ◽  
Gamolwan Tumcharern
2017 ◽  
Vol 196 ◽  
pp. 377-393 ◽  
Author(s):  
Danni Liu ◽  
Shenglu Ji ◽  
Heran Li ◽  
Liang Hong ◽  
Deling Kong ◽  
...  

The exploration of advanced fluorescent probes that can detect divalent copper (Cu2+) in aqueous environments and even in live organisms is particularly valuable for understanding the occurrence and development of Cu2+-related diseases. In this work, we report the design and synthesis of an aggregation-induced emission luminogen (AIEgen)-based probe (TPE-Py-EEGTIGYG) by integrating an AIEgen, TPE-Py, with a peptide, EEGTIGYG, which can selectively detect Cu2+ in both aqueous solution and live cells. Peptide EEGTIGYG has dual functionality in the probe design, namely improving water solubility and providing specific cell membrane-binding ability. TPE-Py-EEGTIGYG can self-assemble into nanoaggregates at high concentration in aqueous solution (e.g., 25 μM), which possess large fluorescence output due to the restriction of intramolecular rotation of the phenyl rings on TPE-Py. The fluorescence of the TPE-Py-EEGTIGYG nanoaggregates can be significantly quenched by Cu2+ but not by other metal ions, achieving the selective detection of Cu2+ in aqueous media. Furthermore, TPE-Py-EEGTIGYG can exist as a molecular species and is very weakly fluorescent in dilute aqueous solution (e.g., 5 μM), but can however largely switch on its fluorescence upon specifically anchoring onto the cell membrane. The emissive probes on the cell membrane can be used for the detection of Cu2+ ions that move in and out of cells with a fluorescence “turn-off” mode.


RSC Advances ◽  
2021 ◽  
Vol 11 (13) ◽  
pp. 7610-7620 ◽  
Author(s):  
Peipei Deng ◽  
Yongyan Pei ◽  
Mengling Liu ◽  
Wenzhu Song ◽  
Mengru Wang ◽  
...  

An iridium(iii) complex-based mitochondria targeting phosphorescent probe for selectively detecting Cu2+ and Cys in aqueous solution, living cells and zebrafish has been developed.


RSC Advances ◽  
2016 ◽  
Vol 6 (82) ◽  
pp. 79020-79027 ◽  
Author(s):  
Che-Yu Lee ◽  
Nai-Yueh Hsu ◽  
Mei-Yao Wu ◽  
Yang-Wei Lin

MW-assisted synthesis of fluorescent BSA-AuNCs for the turn-off sensing of Pb(ii) and turn-on sensing of melamine.


2014 ◽  
Vol 190 ◽  
pp. 279-287 ◽  
Author(s):  
Ke Zhang ◽  
Junkang Guo ◽  
Jingjing Nie ◽  
Binyang Du ◽  
Duanjun Xu

MRS Advances ◽  
2021 ◽  
Author(s):  
J. C. Coyote-Jiménez ◽  
R. E. Zavala-Arce ◽  
M. L. Jiménez-Núñez ◽  
J. L. García-Rivas ◽  
N. A. Rangel-Vázquez ◽  
...  

The Analyst ◽  
2014 ◽  
Vol 139 (24) ◽  
pp. 6352-6356 ◽  
Author(s):  
Narendra Reddy Chereddy ◽  
M. V. Niladri Raju ◽  
Peethani Nagaraju ◽  
Venkat Raghavan Krishnaswamy ◽  
Purna Sai Korrapati ◽  
...  

A naphthalimide based Fe3+ selective fluorescence ‘turn-on’ probe that operates based on a PET mechanism has been synthesized, and its application in the detection of Fe3+ ions in aqueous samples and in live cells is explored.


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