scholarly journals How Accurate Are Electronic Monitoring Devices? A Laboratory Study Testing Two Devices to Measure Medication Adherence

Sensors ◽  
2010 ◽  
Vol 10 (3) ◽  
pp. 1652-1660 ◽  
Author(s):  
Leentje De Bleser ◽  
Sabina De Geest ◽  
Sofie Vandenbroeck ◽  
Johan Vanhaecke ◽  
Fabienne Dobbels
Keyword(s):  
Medication Adherence ◽  
Laboratory Study ◽  
Electronic Monitoring ◽  
Monitoring Devices

scholarly journals PHP30 A SYSTEMATIC LITERATURE REVIEW OF ELECTRONIC MONITORING DEVICES FOR MEASURING MEDICATION ADHERENCE

2009 ◽  
Vol 12 (3) ◽  
pp. A84
Author(s):  
L Shi ◽  
YN Koleva ◽  
P Chhabra ◽  
PD Walker ◽  
A Kalsekar ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Electronic Monitoring ◽  
Monitoring Devices

Patients’ Perceptions of Electronic Monitoring Devices Affect Medication Adherence in Hypertensive African Americans

2008 ◽  
Vol 42 (5) ◽  
pp. 647-652 ◽  
Author(s):  
Antoinette Schoenthaler ◽  
Gbenga Ogedegbe
Keyword(s):  
Primary Care ◽  
African American ◽  
Medication Adherence ◽  
African Americans ◽  
Electronic Monitoring ◽  
Community Based ◽  
Monitoring Period ◽  
Care Practices ◽  
Primary Care Practices ◽  
Monitoring Devices

Background: Electronic monitoring devices (EMDs) are regarded as the gold standard for assessing medication adherence in clinical research. However, little is known about the effect of patients’ acceptance of EMDs on medication adherence in African Americans with hypertension who are followed in primary care practices Objective: To assess patients’ perceptions of EMDs, their acceptance of EMDs, and the relationship of these perceptions to medication adherence in African Americans with hypertension who are followed in community-based practices. Methods: Patients were recruited from a larger randomized controlled trial assessing the effect of motivational interviewing on medication adherence and blood pressure in hypertensive African American patients followed in 2 New York City primary care practices. Medication adherence was assessed with a Medication Event Monitoring System (MEMS) during a 12-month monitoring period. At the 12-month follow-up, patients’ perceptions of the MEMS were assessed with a 17-item questionnaire. ANOVA was used to compare patients’ responses (agree, neither, disagree) with the MEMS adherence over the monitoring period. Tukey's post hoc tests were used to determine whether there were significant differences among the 3 groups. Results: Participants were predominantly women, low-income, unemployed, had a high school education, and were a mean age of 53 years. Approximately two-thirds of the participants stated that the MEMS helped them remember to take their medications, 93% reported that the MEMS was easy to open, 85% did not find it stressful, and 75% liked the MEMS and used it everyday. One-third of patients preferred using a pillbox and 25% did not like traveling with the MEMS. Patients who stated that they used the MEMS every day, felt comfortable using it in front of others, and remembered to put refills in the MEMS had significantly better adherence over the study period than did those who disagreed (p ≤ 0.05). Conclusions: African American patients treated for hypertension in community-based practices held positive perceptions about a MEMS. Perceptions about the practicality of a MEMS may yield important information about actual medication-taking behavior.

scholarly journals Feasibility of Electronic Monitoring of Daily Oral Medications in Adolescents with Sickle Cell Disease

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 4701-4701
Author(s):  
Lori E Crosby ◽  
Katherine M Kidwell ◽  
Aimee K Hildenbrand ◽  
Charles T. Quinn ◽  
Meghan E Mcgrady
Keyword(s):  
Medication Adherence ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Electronic Monitoring ◽  
Cell Disease ◽  
Oral Medications ◽  
Adherence Assessment ◽  
Monitoring Devices ◽  
Initial Uptake

Background: The field has made significant strides in understanding the mechanisms underlying pediatric sickle cell disease (SCD), and the coming years will likely see the approval of several new medications to treat SCD. The impact of these medications on clinical outcomes, however, will be dependent on patient adherence. Adolescents with SCD are at particular risk for non-adherence, and as disease management increasingly includes self-administration of oral medications, adherence assessment will become a critical component of research on medication effectiveness and clinical care. While electronic monitoring devices (bottles with computer chips that record date- and time-stamps of device openings) such as MEMS® bottles are considered the "gold standard" for adherence assessment in other populations, their feasibility among adolescents with SCD remains unknown. Objectives: The primary aims of this study were to examine data on MEMS® bottle use among adolescents (ages 13-21 years) with SCD to: 1) evaluate the feasibility of MEMS® bottle use; and 2) elicit barriers and facilitators to MEMS® bottle use. Methods: As part of a larger study of a self-management intervention, adolescents were asked to use a MEMS® bottle to store and administer their daily oral medication (hydroxyurea or deferasirox) for the 18-week study duration. The larger study included baseline, post-treatment, and follow-up assessments, at which adolescents were asked to provide their MEMS® bottle for data download. Descriptive statistics were calculated to assess multiple domains of MEMS® bottle feasibility including: initial uptake (% enrolled), MEMS® initiation (% initiated), and MEMS® sustained use (% completed; % provided bottles for download ±2 weeks of scheduled study visit = "on time"). Barriers and facilitators to MEMS® use were elicited via adolescent self-report. Results: In the larger study, 18 non-Hispanic African-American adolescents (M = 17.8 years, SD = 2.6; 61% male) with HbSS were asked to use a MEMS® bottle to store their hydroxyurea (n = 14) or deferasirox (n = 4). Initial uptake was 94.7%, with 18 of 19 eligible adolescents enrolling in the study. Of the 18 enrolled adolescents, all initiated MEMS® use (100%) and 11 sustained MEMS® use through the final study endpoint (61.1%). Eight (44.4%) and 2 (11.1%) adolescents provided their MEMS® bottle for download "on time" at post-treatment (42 days) and follow-up (126 days), respectively. Barriers to MEMS® use included medication changes (i.e., medication holds, dose timing changes) and transitioning from pediatric to adult care. Facilitators included tip sheets (e.g., places to store bottle, reminder to place refills in bottle) and reminder calls. Participants took a median of 26.2% of doses using the MEMS® across the 126 days (SD = 22.4; range 0.79% - 79.3%), illustrating that electronic monitoring devices are not a solution to medication adherence, but are one component of an adherence support strategy. See Figure 1 for adherence rates over time. Discussion: Data suggest that MEMS® are acceptable to adolescents with SCD. Ensuring sustained MEMS® use, however, will likely require additional supports. For example, electronic monitors which automatically transmit data in real-time via Bluetooth or cellular connections would eliminate the need for adolescents to bring bottles to study visits for data downloads. Researchers and clinicians interested in using electronic monitoring devices are encouraged to consider remote monitoring capabilities along with other device features when selecting a product. Larger studies are needed to evaluate concordance between rates of adherence obtained via electronic monitoring and other assessments and to validate electronically-monitored medication adherence with clinically-relevant outcomes for adolescents with SCD. Figure 1 Disclosures Quinn: Celgene: Membership on an entity's Board of Directors or advisory committees; Amgen: Other: Research Support.

scholarly journals Nonadherence in the era of severe asthma biologics and thermoplasty

2018 ◽  
Vol 51 (4) ◽  
pp. 1701836 ◽  
Author(s):  
Joy Lee ◽  
Tunn Ren Tay ◽  
Naghmeh Radhakrishna ◽  
Fiona Hore-Lacy ◽  
Anna Mackay ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Severe Asthma ◽  
Clinical Assessment ◽  
Electronic Monitoring ◽  
Novel Therapies ◽  
Clinical Assessments ◽  
Asthma Patients ◽  
Difficult Asthma ◽  
Monitoring Devices ◽  
Clinician Assessment

Nonadherence to inhaled preventers impairs asthma control. Electronic monitoring devices (EMDs) can objectively measure adherence. Their use has not been reported in difficult asthma patients potentially suitable for novel therapies, i.e. biologics and bronchial thermoplasty.Consecutive patients with difficult asthma were assessed for eligibility for novel therapies. Medication adherence, defined as taking >75% of prescribed doses, was assessed by EMD and compared with standardised clinician assessment over an 8-week period.Among 69 difficult asthma patients, adherence could not be analysed in 13, due to device incompatibility or malfunction. Nonadherence was confirmed in 20 out of 45 (44.4%) patients. Clinical assessment of nonadherence was insensitive (physician 15%, nurse 28%). Serum eosinophils were higher in nonadherent patients. Including 11 patients with possible nonadherence (device refused or not returned) increased the nonadherence rate to 31 out of 56 (55%) patients. Severe asthma criteria were fulfilled by 59 out of 69 patients. 47 were eligible for novel therapies, with confirmed nonadherence in 16 out of 32 (50%) patients with EMD data; including seven patients with possible nonadherence increased the nonadherence rate to 23 out of 39 (59%).At least half the patients eligible for novel therapies were nonadherent to preventers. Nonadherence was often undetectable by clinical assessments. Preventer adherence must be confirmed objectively before employing novel severe asthma therapies.

scholarly journals Relations between cognitive status and medication adherence in patients treated for memory disorders

2012 ◽  
Vol 3 (1) ◽  
pp. 2 ◽  
Author(s):  
Raymond L. Ownby ◽  
Christopher Hertzog ◽  
Sara J. Czaja
Keyword(s):  
Medication Adherence ◽  
Electronic Monitoring ◽  
Cognitive Status ◽  
Path Model ◽  
Elderly Persons ◽  
Poor Health Status ◽  
Memory Problems ◽  
Treatment Conditions ◽  
Electronic Monitoring Device ◽  
Over Time

Medication adherence has been increasingly recognized as an important factor in elderly persons’ health. Various studies have shown that medication non-adherence is associated with poor health status in this population. As part of a study of the effects of two interventions to promote medication adherence in patients treated for memory problems, information on medication adherence and cognitive status was collected at 3-month intervals. Twenty-seven participants (16 men, 11 women, age 71-92 years) were assigned to control or treatment conditions and adherence was evaluated with an electronic monitoring device. Cognitive status was evaluated at 3- month intervals beginning in April of 2003 and continuing through September of 2006. We have previously reported on the effectiveness of these interventions to promote adherence. In this paper, we examine the relations of cognitive status and adherence over time using a partial least squares path model in order to evaluate the extent to which adherence to cholinesterase medications was related to cognitive status. Adherence predicted cognitive status at later time points while cognition did not, in general, predict adherence. Results thus suggest that interventions to ensure high levels of medication adherence may be important for maintaining cognitive function in affected elderly people.

scholarly journals Assessing Medication Adherence Simultaneously by Electronic Monitoring and Pill Count in Patients With Mild-to-Moderate Hypertension

2010 ◽  
Vol 23 (2) ◽  
pp. 149-154 ◽  
Author(s):  
H. A. W. van Onzenoort ◽  
W. J. Verberk ◽  
A. G. H. Kessels ◽  
A. A. Kroon ◽  
C. Neef ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Moderate Hypertension ◽  
Electronic Monitoring ◽  
Pill Count

scholarly journals Reliability and effective use of electronic trap monitoring systems based on cellular networks

2021 ◽  
Author(s):  
Anthony R. Martin
Keyword(s):  
Cellular Networks ◽  
Electronic Monitoring ◽  
Monitoring Systems ◽  
Trap Door ◽  
Invasive Species Control ◽  
Large Numbers ◽  
Mobile Phone Networks ◽  
Effective Use ◽  
Cellular Mobile ◽  
Monitoring Devices

AbstractThe deployment of cage traps rather than kill traps can greatly reduce non-target mortality in an invasive species control/eradication operation, but their use is normally constrained by the need for them to be checked frequently on animal welfare grounds. This paper examines the reliability of electronic monitoring devices that use cellular (mobile phone) networks to alert the operator when a trap door closes, and also discusses the management network that is needed to convert an alarm into a timely trap visit without fail. The two monitoring systems tested were 100% reliable in notifying the operator when a trap door closed, and their use reduced the burden of trap visits by 98% compared to the standard protocol of daily checks. As such, these systems can be of great value to campaigns operating large numbers of traps, especially when capture rates are low.

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