scholarly journals Zein/Bioactive Glass Coatings with Controlled Degradation of Magnesium under Physiological Conditions: Designed for Orthopedic Implants

Prosthesis ◽  
2020 ◽  
Vol 2 (3) ◽  
pp. 211-224 ◽  
Author(s):  
Muhammad Atiq Ur Rehman
Keyword(s):  
Bioactive Glass ◽  
Electrochemical Impedance ◽  
Composite Coatings ◽  
Orthopedic Implants ◽  
Open Circuit ◽  
Practical Application ◽  
Binding Ability ◽  
Physiological Conditions ◽  
Biomedical Device

Magnesium and its alloys are widely considered as temporary bio-implants owing to their mechanical properties and biocompatibility. However, the high corrosion rates and degradation in the physiological environment restrict the practical application of Mg as a biomedical device. Therefore, in this study, Zein/45S5 bioactive glass (BG) coatings were deposited via electrophoretic deposition (EPD) on pretreated pure magnesium (Mg) substrates, which controls the rapid degradation of magnesium. The set of EPD parameters was first optimized on stainless steel (SS) and then the optimum EPD parameters were applied to obtain zein/BG composite coatings on Mg substrates. The morphology of the obtained coatings was studied by scanning electron microscopy (SEM). SEM results showed that both zein and BG were successfully deposited on the surface of the Mg substrate. Electrochemical measurements consisting of open circuit potential (OCP), electrochemical impedance spectroscopy (EIS), and potentiodynamic polarization confirmed that the corrosion resistance of Mg improved after the deposition of zein/BG coatings. The in-vitro bioactivity study was carried out by immersing the zein/BG coatings in simulated body fluid for 3, 7, and 21 days. SEM, energy dispersive X-ray spectroscopy (EDX), and Fourier transform infrared spectroscopy results elucidated that the hydroxyapatite layer developed after 21 days of immersion in SBF, which confirmed the bone binding ability of the coatings.

scholarly journals Synthesis and Characterization of Silver–Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 34
Author(s):  
Shaher Bano ◽  
Memoona Akhtar ◽  
Muhammad Yasir ◽  
Muhammad Salman Maqbool ◽  
Akbar Niaz ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Bone Diseases ◽  
Osteogenic Potential ◽  
Diffusion Method ◽  
Charge Composition ◽  
In Vitro Bioactivity ◽  
Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc., are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag)- and strontium (Sr)-doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ and Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two-ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in vitro bioactivity. The Ag-Sr MBGNs synthesized in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

Polyaniline/Epoxy Composite Emulsion Coatings for Anticorrosion to Mild Steel

2010 ◽  
Vol 152-153 ◽  
pp. 1890-1893
Author(s):  
Yu Feng Li ◽  
Liu Yang ◽  
Xiao Hui Gao ◽  
Zhao Po Zeng
Keyword(s):  
Electron Microscope ◽  
Mild Steel ◽  
Aqueous Medium ◽  
Electrochemical Impedance ◽  
Composite Coatings ◽  
Energy Dispersive Spectrometer ◽  
Open Circuit ◽  
Water Dispersible ◽  
Anticorrosion Coatings ◽  
Waterborne Epoxy Resin

Doped water-dispersible polyaniline (PANI) emulsion were synthesized by emulsion polymerization in aqueous medium and characterized by dc conductivity and Transmission electron microscope (TEM). The results showed the PANI has bar-like shape and the diameter is about 200nm. The composite anticorrosion coatings of PANI emulsion and waterborne epoxy resin emulsion (EP) were prepared by mixture in aqueous medium and used for corrosion protection of mild steel. Open circuit potential (OCP) and Electrochemical impedance spectroscopy (EIS) demonstrated that the PANI/EP composite coatings have better anticorrosion properties than EP. It’s impedance and corrosion potential is higher. Scanning electron microscope (SEM) and Energy dispersive spectrometer (EDS) showed that the oxidation film formed on the metal surface and prevent corrosion effectively. The anticorrosion coatings are environmental friendly because of water dispersion medium.

Electrochemical Determination of the Corrosion Resistance of Ag-Pd Dental Alloys

2008 ◽  
Vol 59 (9) ◽  
Author(s):  
Daniel Mareci ◽  
Igor Cretescu ◽  
Neculai Aelenei ◽  
Julia Claudia Mirza Rosca
Keyword(s):  
Corrosion Resistance ◽  
Open Circuit Potential ◽  
Electrochemical Impedance ◽  
Corrosion Behaviour ◽  
Artificial Saliva ◽  
Surface Film ◽  
Electrochemical Determination ◽  
Open Circuit ◽  
Electrochemical Characteristics

The electrochemical behavior of a three Ag-Pd alloys used in dental prosthetics construction for crowns and bridges was studied in artificial saliva using the polarization curves and electrochemical impedance spectroscopy (EIS). The corrosion resistance was evaluated by means of the corrosion currents value and by coulometric analysis. The open circuit potential of Ag-Pd are attributed to dealloying followed by surface enrichment with Ag and the possible formation of an insoluble AgCl surface film on the respective alloy surfaces. Our results have shown that these alloys have a somewhat good corrosion resistance in artificial saliva. When increasing the content of Cu, corrosion resistance decreases. The passivation of all samples occurred spontaneously at the open circuit potential. The electrochemical properties of the spontaneously passivated electrodes at the open circuit potential were studied by EIS. The polarization resistance (Rp) and the electrode capacitance (Cdl) were determined. The polarisation resistance of all the samples increases with the immersion time. The polarization resistances are largest and decrease when increasing the content of Cu. Cu reduces the Ag-Pd alloy corrosion resistance. The present study, thought limited, has shown that electrochemical characteristics can be use to identify such alloys. Knowledge of the in vitro corrosion behaviour of these alloys may lead to better understanding of any biologically adverse effects in vitro.

scholarly journals The effect of Streptococcus mutans on the Corrosion Behavior of Nickel-Titanium Dental Alloys - In Vitro Study

2019 ◽  
Vol 8 (6) ◽  
pp. 435-440
Author(s):  
Asmaa Marda ◽  
Khadija Mouflih ◽  
Abdelkebir Bellaouchou ◽  
Abdallah Guenbour ◽  
Asmae Elmansari ◽  
...  
Keyword(s):  
Streptococcus Mutans ◽  
Electrochemical Impedance ◽  
Artificial Saliva ◽  
In Vitro Study ◽  
Oral Bacteria ◽  
Open Circuit ◽  
Nickel Titanium ◽  
Dental Alloys ◽  
Enrichment Medium

This study aimed to compare the resistance of dental alloys to corrosion in a solution containing oral bacteria named Streptococcus mutans (S.mutans). The electrochemical behavior of Nickel-Titanium (NiTi) was investigated in sterile Fusayama artificial saliva (AS) with the enrichment medium tryptic soy broth (TSB) in solution 1 and (AS) with (TSB) and bacteria in solution 2. The electrochemical procedures selected for this work were open circuit potentials (OCP), Potentiodynamic polarization (PDP), and electrochemical impedance spectroscopy (EIS). The NiTi surface was examined using optical microscopy.      After 24 hours of immersion in artificial saliva, the results have shown that NiTi revealed high corrosion reactivity in the presence of S. mutans and present pitting corrosion on the surface.

scholarly journals Development and Characterization of Bioactive Glass Containing Composite Coatings with Ion Releasing Function for Antibiotic-Free Antibacterial Surgical Sutures

Materials ◽  
2019 ◽  
Vol 12 (3) ◽  
pp. 423 ◽  
Author(s):  
Francesca Ciraldo ◽  
Kristin Schnepf ◽  
Wolfgang Goldmann ◽  
Aldo Boccaccini
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Dip Coating ◽  
Carbonate Apatite ◽  
Polymeric Layer ◽  
Surgical Sutures ◽  
Dip Coating Technique ◽  
Doped Glass

Resorbable (Vicryl® Plus) sutures were coated with zinc-doped glass (Zn-BG) and silver-doped ordered mesoporous bioactive glass (Ag-MBG) particles by a dip coating technique. A multilayer approach was used to achieve robust coatings. The first coating was a polymeric layer (e.g., PCL or chitosan) and the second one was a composite made of BG particles in a polymer matrix. The coatings were characterized in terms of morphology by scanning electron microscopy (SEM), in vitro bioactivity, and antibacterial properties. Chitosan/Ag-MBG coatings showed the ability to form hydroxyl-carbonate-apatite on their surfaces after immersion in SBF. An antibacterial effect against Gram (+) and Gram (-) bacteria was confirmed, highlighting the potential application of the coated sutures for antibiotic-free approaches.

Development of 45S5/PEEK Bioactive Coatings by Cold Gas Spray for Orthopedic Implants

2021 ◽  
Author(s):  
B. Garrido ◽  
V. Albaladejo-Fuentes ◽  
I.G. Cano ◽  
S. Dosta
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Orthopedic Implants ◽  
Deposition Efficiency ◽  
Polymeric Matrix ◽  
Friction Behavior ◽  
Bioactive Coatings ◽  
Bone Implant ◽  
Orthopedic Applications ◽  
Cold Gas

Abstract Cold Gas Spray (CGS) technology has allowed the development of biofunctional composite coatings composed of 45S5 and Polyetheretherketone (PEEK). The combination of a bioactive glass material embedded in a biocompatible polymeric matrix becomes this new composite in an interesting material for orthopedic applications since meet the biomechanical and biological requirements of an artificial implant. In the present study, blends of bioactive glass 45S5 and PEEK powder with different granulometry and 45S5/PEEK ratio have been prepared. These mixtures of powders have been deposited onto PEEK substrates by CGS with the goal of incorporating a bioactive additive to the biocompatible polymer, which can improve the bone-implant interaction of PEEK. The deposition efficiency (DE) and thickness of the coatings have been evaluated and from the results obtained, it was possible to conclude that DE and coating thickness are significantly affected by the granulometry and by the 45S5/PEEK ratio of the blends. By Scanning Electron Microscopy (SEM) inspection, it was observed that the use of blends with high 45S5/PEEK ratio led to the deposition of coatings with high content of 45S5 particles embedded in the polymeric matrix. Finally, the friction behavior of the coatings was analyzed performing ball-on-disk tests and these experiments showed that the presence of glass particles has a beneficial role in the wear resistance of the coatings.

scholarly journals Synthesis and Characterization of Silver–Strontium (Ag-Sr) Doped Mesoporous Bioactive Glass Nanoparticles

2021 ◽  
Author(s):  
Shaher Bano ◽  
Memoona Akhtar ◽  
Muhammad Yasir ◽  
Muhammad Salman Maqbool ◽  
Akbar Niaz ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Bone Diseases ◽  
Osteogenic Potential ◽  
Diffusion Method ◽  
Charge Composition ◽  
In Vitro Bioactivity ◽  
Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc. are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag) and strontium (Sr) doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ & Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in-vitro bioactivity. The Ag-Sr MBGNs synthesize in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

In vitro study of polycaprolactone/bioactive glass composite coatings on corrosion and bioactivity of pure Mg

2015 ◽  
Vol 355 ◽  
pp. 832-841 ◽  
Author(s):  
Yuyun Yang ◽  
Carolin Michalczyk ◽  
Ferdinand Singer ◽  
Sannakaisa Virtanen ◽  
Aldo R. Boccaccini
Keyword(s):  
Bioactive Glass ◽  
Composite Coatings ◽  
In Vitro Study ◽  
Vitro Study ◽  
Glass Composite

scholarly journals A Brief Insight to the Electrophoretic Deposition of PEEK-, Chitosan-, Gelatin-, and Zein-Based Composite Coatings for Biomedical Applications: Recent Developments and Challenges

Surfaces ◽  
2021 ◽  
Vol 4 (3) ◽  
pp. 205-239
Author(s):  
Syeda Ammara Batool ◽  
Abdul Wadood ◽  
Syed Wilayat Hussain ◽  
Muhammad Yasir ◽  
Muhammad Atiq Ur Rehman
Keyword(s):  
Electrophoretic Deposition ◽  
Composite Coatings ◽  
Antibacterial Properties ◽  
Orthopedic Implants ◽  
Biologically Active ◽  
Metallic Ions ◽  
Chemical Structures ◽  
Main Challenge

Electrophoretic deposition (EPD) is a powerful technique to assemble metals, polymer, ceramics, and composite materials into 2D, 3D, and intricately shaped implants. Polymers, proteins, and peptides can be deposited via EPD at room temperature without affecting their chemical structures. Furthermore, EPD is being used to deposit multifunctional coatings (i.e., bioactive, antibacterial, and biocompatible coatings). Recently, EPD was used to architect multi-structured coatings to improve mechanical and biological properties along with the controlled release of drugs/metallic ions. The key characteristics of EPD coatings in terms of inorganic bioactivity and their angiogenic potential coupled with antibacterial properties are the key elements enabling advanced applications of EPD in orthopedic applications. In the emerging field of EPD coatings for hard tissue and soft tissue engineering, an overview of such applications will be presented. The progress in the development of EPD-based polymeric or composite coatings, including their application in orthopedic and targeted drug delivery approaches, will be discussed, with a focus on the effect of different biologically active ions/drugs released from EPD deposits. The literature under discussion involves EPD coatings consisting of chitosan (Chi), zein, polyetheretherketone (PEEK), and their composites. Moreover, in vitro and in vivo investigations of EPD coatings will be discussed in relation to the current main challenge of orthopedic implants, namely that the biomaterial must provide good bone-binding ability and mechanical compatibility.

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