scholarly journals Germanium-Titanium-π Polymer Composites as Functional Textiles for Clinical Strategy to Evaluate Blood Circulation Improvement and Sexual Satisfaction

Polymers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 4154
Author(s):  
Yu-Cing Juho ◽  
Shou-Hung Tang ◽  
Yi-Hsin Lin ◽  
Chen-Xi Lin ◽  
Tenson Liang ◽  
...  

By continuously enhancing the blood flow, far-infrared (FIR) textile is anticipated to be a potential non-pharmacological therapy in patients with peripheral vascular disorders, for instance, patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) and experiencing vasculogenic erectile dysfunction (VED). Hence, we manufactured a novel polymer composite, namely, germanium-titanium-π (Ge-Ti-π) textile and aimed to evaluate its characteristics and quality. We also investigated the immediate and long-term effects of the textile on patients with ESRD undergoing HD and experiencing VED. The Ge-Ti-π textile was found to have 0.93 FIR emissivity, 3.05 g/d strength, and 18.98% elongation. The results also showed a 51.6% bacteria reduction and negative fungal growth. On application in patients receiving HD, the Ge-Ti-π textile significantly reduced the limb numbness/pain (p < 0.001) and pain score on the visual analog scale (p < 0.001). Moreover, the Doppler ultrasound assessment data indicated a significant enhancement of blood flow in the right hand after 1 week of Ge-Ti-π textile treatment (p < 0.041). In VED patients, the Ge-Ti-π underpants treatment significantly improved the quality of sexual function and increased the average penile blood flow velocity after 3 months of the treatment. Our study suggests that the Ge-Ti-π textile could be beneficial for patients with blood circulation disorders.

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Eva Paraskevi Andronikidi ◽  
Glykeria Tsouka ◽  
Myrto Giannopoulou ◽  
Konstantinos Botsakis ◽  
Xanthi Benia ◽  
...  

Abstract Background and Aims Renal transplantation is considered the most effective and less costly modality of renal replacement therapy in patients with end stage renal disease. The disparity between kidney allografts and recipients has led to a global effort to increase the pool of kidney donors. Accordingly, fibromuscular dysplasia (FMD) is no longer considered an absolute contraindication for kidney donation. The incidence of FMD is about 2.3%-5.8% in potential kidney donors. There are few cases in the literature where renal artery stenosis in allografts with known pre-transplantation FMD became worse after transplantation, indicating the importance of a proper follow up in the recipients. This is a case of a living kidney donor with no history of hypertension, proteinuria or elevated serum creatinine, whose intra-arterial digital subtraction angiography revealed FMD lesions in the left renal artery. Method Case report Results A 54-year-old Caucasian female with medical history of hypothyroidism took the decision to offer her kidney to her 37-year-old son who was diagnosed with end-stage renal disease five years ago secondary to diabetes mellitus type I. She had no history for diabetes, hypertension and renal disease. Her vital signs on admission were heart rate of 78 beats/min and blood pressure of 130/70 mmHg. Urinalysis, biochemical profile and serological evaluations were all within normal ranges. Blood urea was 36 mg/dL and serum creatinine was 0.6 mg/dL (eGFR 97ml/min/1.73m2). The abdominal ultrasound and renogram with Tc-99m DTPA showed no remarkable findings. On intra-arterial digital subtraction angiography an abnormal succession of dilatations and multifocal stenoses of the left renal artery, characteristic of medial FMD, was found. The right renal artery was normal. Apart from a dysfunctional permanent left femoral catheter, the patient had no other vascular access for hemodialysis because of Superior Vena Cava syndrome, so he needed urgent transplantation. Taking all of these into consideration, the patient was offered renal transplantation as the best option. A left open donor nephrectomy was performed; the renal artery was divided distal to the stenotic dysplastic area. The allograft was placed at the right iliac fossa of the recipient with arterial and venous anastomosis to the extrarenal iliac vessels. Post-operatively, the recipient had a delayed graft function lasted 13 days. On renal artery Doppler in the allograft we found increased resistance index (RI) that gradually normalized without any intervention. An immunosuppressive regiment of tacrolimus, mycophenolate and prednisone was administered according to our center protocol. At discharge serum creatinine was 1.7 mg/dL (eGFR: 50ml/min/1.73m2). At the year follow-up, the donor was normotensive and had near normal renal function (Cr:1.3mg/dL, eGFR: 70ml/min/1.73m2). The recipient has a well-controlled blood pressure receiving two antihypertensive drugs and maintains a satisfactory renal function. Conclusion Few cases with FMD in renal allografts from living and deceased donors have been described. In a review of 4 studies the authors concluded that the outcome of transplantation with allografts from living donors with medial FMD was satisfactory and these allografts could be used to increase the donor pool. Furthermore, it is strongly recommended to have a thorough pre-transplantation check of the donor as well as a close monitoring of both the donor and recipient after transplantation. This case shows that allografts harvested from carefully selected donors with renal arterial FMD can be successfully used, particularly in urgent conditions. Detailed pre-tranplantation imaging of donor’s renal arteries, selection of the appropriate screening method, as well as close monitoring of both donor and recipient for early interventions after transplantation is of paramount importance.


Author(s):  
Natalie Ebert ◽  
Elke Schaeffner

Both acute and chronic states of kidney disease have considerable healthcare impact as they can produce enormous disease burden and costs. To classify chronic kidney disease into the CKD staging system, glomerular filtration rate as an index of kidney function, as well as albuminuria as a marker of kidney damage have to be assessed as correctly as possible. Misclassification is a serious concern due to the difficulties in precise GFR assessment and correct interpretation of results. Differentiating between pure senescence and true disease among older adults can be a delicate issue. To find the right renal replacement option for individuals that progress to end-stage renal disease can be challenging, and some older patients may even benefit from conservative care without dialysis. To prevent acute kidney injury as a frequent and potentially life-threatening complication, clinicians need to develop an understanding of the common vulnerability to kidney damage among older adults.


2019 ◽  
Vol 59 (4) ◽  
pp. 210-213
Author(s):  
Supawon Srettabunjong

A high risk of suicide has been observed in adults with end-stage renal disease who are undergoing haemodialysis. Since suicide is preventable, early screening, a prompt multidisciplinary approach and appropriate treatment of depression are critical and are recommended to treating physicians. Recently, the case of a woman with end-stage renal disease who had been undergoing haemodialysis was encountered. She died by suicide after self-severing the temporary haemodialysis catheter secured to the right side of her neck. This method of suicide is unusual and rare. This case not only underscores the association between haemodialysis and suicide in patients with end-stage renal disease but also raises awareness of the possibility of such deaths.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Erica Melo ◽  
Marcelo Silveira ◽  
Sérgio Souza ◽  
Ana Baptista ◽  
Filipe Miranda ◽  
...  

Abstract Background and Aims In patients with end-stage renal disease (ESRD), the use of cuffed, tunneled dialysis catheters (TDCs) for hemodialysis has become integral to treatment plans. Fluoroscopy is a widely accepted method for the insertion and positioning of cuffed dialysis catheters, because it is easy to use, accurate and reliable, and has a relatively low incidence of complications. The purpose of our study was to evaluate the feasibility of tunneled hemodialysis catheter placement without the use of fluoroscopy but with a dynamic ultrasound-imaging-based guided technique. Method From January 2015 to December 2017, we performed an observational prospective cohort study of 56 patients with ERDS who required TDC placement. Results The overall success rate for ultrasound-guided central access was 100%, with a mean number of 1.16 (± 0.4) attempts per patient. There were no incidences of guide wire coiling/kinking, carotid puncture, pneumothorax, or catheter malfunction. Catheter flow during dialysis was 286 (± 38) ml/min. The total number of catheter days was 7,451, with a mean of 133 days and a range of 46 to 322 days. Life table analysis revealed primary patency rates of 100%, 96%, and 53% at 30, 60, and 120 days, respectively. Conclusion Dynamic ultrasound-based visualization of microbubbles in the right atrium is a highly accurate method to detect percutaneous implantation of large-lumen, tunneled, central venous catheters without the need for fluoroscopic guidance technology.


2006 ◽  
Vol 50 (5) ◽  
pp. 963-967 ◽  
Author(s):  
Christianne T.S. Leal ◽  
Paulo G.S. Lacativa ◽  
Elaine M.S. Gomes ◽  
Reinaldo C. Nunes ◽  
Flávio Luiz F. de S. Costa ◽  
...  

Brown tumors are relatively uncommon but they are serious complications of renal osteodystrophy. We describe a 31-year-old woman with end-stage renal disease who had undergone hemodialysis for nine years and developed severe secondary hyperparathyroidism and a maxilla brown tumor despite increasing doses of oral calcitriol and calcium carbonate. The fast increase of the right maxillary bone tumor led to indication of parathyroidectomy (PTx). Despite normalization of serum PTH there was a slow regression of the mass and the patient still complained about her appearance after two-years of follow-up. Excision of the maxillary mass followed by recontouring of the maxilla was then performed, with adequate masticator rehabilitation.


Breast Care ◽  
2017 ◽  
Vol 13 (1) ◽  
pp. 44-46 ◽  
Author(s):  
Kyoung Min Lee ◽  
Jee Eun Lee ◽  
Eun Suk Cha ◽  
Jin Chung ◽  
Jeoung Hyun Kim ◽  
...  

Background: Soft tissue calcification is common in patients with secondary hyperparathyroidism who have received long-term treatment with hemodialysis. However, calcifications in the breast parenchyma are not common. We report a case of a woman with dystrophic breast calcifications from secondary hyperparathyroidism. Case Report: A 65-year-old woman presented with a palpable mass in her right breast which she had discovered 1 month ago. She had a medical history of end-stage renal disease. Mammography and ultrasound revealed large dystrophic calcifications in both breasts. Core needle biopsy was performed for calcifications in the right breast, and the pathologic diagnosis was dystrophic calcification in the stroma from secondary hyperparathyroidism. Conclusion: Reviewing our case will contribute to a fast and correct diagnosis in patients with dystrophic breast calcifications and lab results indicating secondary hyperparathyroidism, and will help discriminate these benign lesions from malignancies.


2016 ◽  
Vol 1 (2) ◽  

Objective: The arterial needle placement in arteriovenous fistula (AVF) can either be antegrade (in the direction of blood flow or pointing towards the heart) or retrograde (against the direction of blood flow) while venous needle placement should always be in the same direction as the blood flow. This study determined the effects of arterial needle placement in the arteriovenous fistula on dialysis adequacy of End-Stage Renal Disease (ESRD) patients undergoing maintenance hemodialysis in United Candelaria Doctors Hospital - Nephro Synergies Inc. (UCDHNSI) Hemodialysis Center. Methods: A randomized controlled trial design was used in the study. A total of 20 non-diabetic, non-cardiac patients on maintenance hemodialysis for more than 6 months were randomized either to the intervention group (patients’ AVF were cannulated in a retrograde manner) or the control group (patients’ AVF were cannulated in an antegrade manner). Urea reduction ratio (URR) and Kt/V as well as access recirculation percentage were used to determine dialysis adequacy. Pre-dialysis, in the first 30 minutes of dialysis initiation and post-dialysis blood samples were obtained in each patient in 6 succeeding hemodialysis considering dialyzer reuse up to fifth reuse. Means were compared by independent t-test. Results: The findings of the study revealed that the mean URR and Kt/V of the subjects cannulated in retrograde manner and antegrade manner were 69.35% and 1.45, and 74.65% and 1.70, respectively. The mean access recirculation percentage of the subjects was 4.65% in the intervention group and 3.02% in the control group. There was a significant difference on URR and Kt/V of the subjects using retrograde and antegrade arterial needle placement in 6 succeeding hemodialysis sessions. There was no significant difference on access recirculation percentage of the subjects using retrograde and antegrade arterial needle placement in 6 succeeding hemodialysis sessions. Conclusions: Antegrade arterial needle placement provides more adequate hemodialysis than retrograde arterial needle placement in terms of URR and Kt/V values among non-diabetic, non-cardiac patients undergoing maintenance hemodialysis in 6 succeeding hemodialysis sessions. The directions of the arterial needle either retrograde and antegrade did not have significant effects on access recirculation.


2021 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Nurul Pradita ◽  
Kiki Hardiansyah Safitri

Literature Review : Efektivitas Terapi Non Farmakologi Terhadap Penurunan Tekanan Darah Pada Pasien End Stage Renal Disease Yang Menjalani Hemodialisis Nurul Pradita1, Kiki Hardiansyah Safitri2 1 Mahasiswa Program Studi NERS, ITKES Wiyata Husada, Jl.Kadrie Oening No 77 Samarinda, Kalimantan Timur e-mail : [email protected] 2Dosen, ITKES Wiyata Husada, Jl.Kadrie Oening No 77 Samarinda, Kalimantan Timur e-mail : [email protected]   ABSTRAK   Latar Belakang: End Stage renal disease (ESRD) bisa disebabkan oleh tekanan darah yang tidak terkontrol  (hipertensi) atau  penyakit ginjal dapat menyebabkan hipertensi. Terapi non farmakologi dapat membantu pasien mengatasi tekanan darah dengan efek samping yang minimal. Tujuan: Mengidentifikasi studi literatur efektifitas terapi non farmakologi terhadap penurunan tekanan darah pada pasien end stage renal disease. Metode: Desain penelitian Literature  Review, online database adalah jurnal Science Direct, PubMed(NCBI), google scholar. Jurnal yang digunakan dalam kurun kurun waktu 2012-2020, pencarian menggunakan Populasi : pasien ESRD dengan hipertensi, intervensi :terapi non farmakologi, comparison: terapi komplomentar, outcome:penurunan tekanan darah, study design : literature review dan quasi experiment. Hasil: Didapatkan 6893 jurnal, diseleksi menggunakan kriteria inklusi dan ekslusi,melalui diagram prisma didapatkan menjadi 12 jurnal. Terapi non farmakologi yang digunakan adalah progressive muscel relaxation (4 jurnal); terapi massase (1 jurnal ); terapi music (4 jurnal); intradialitic exercise (4 jurnal) Kesimpulan: Terapi non farmakologi bermakna di dalam studi literature untuk menurunkan tekanan darah yang bekerja dengan prinsip relaksasi, berpengaruh dalam peningkatan hormon endorphin yang menyebabkan pembuluh darah berdilatasi sehingga tekanan darah mengalami penurunan. Kata Kunci : Terapi Non farmakologi, Hipertensi , End Stage Renal Disease   ABSTRACT   Background: End Stage Renal Disease (ESRD) can be caused by uncontrolled blood pressure (hypertension) or kidney disease can cause hypertension. Non-pharmacological therapy can help patients with blood pressure with minimal side effects. Objective: To conduct a literature study on the effectiveness of non-pharmacological therapies in reducing blood pressure of End Stage Renal Disease patients. Method: Literature Review research design, the data were obtained from online database such as Science Direct, PubMed (NCBI), and google scholar in the period of 2012-2020. The Population in this study was ESRD patients with hypertension and the intervention given were non-pharmacological therapies, comparison: commentary therapy, outcome: lowering blood pressure, study design: literature review and quasi experiment. Results: There were 6893 journals, selected using inclusion and exclusion criteria, through the PRISMA diagram they were narrowed down into 12 journals. The non-pharmacological therapies used were progressive muscle relaxation (4 journals); massage therapy (1 journal); music therapy (4 journals); and intradialytic exercise (4 journals). Conclusion: Non-pharmacological therapy is significant in literature studies to reduce blood pressure which works with the principle of relaxation. Further, it has an effect in increasing the endorphin hormone which causes blood vessels to dilate and lead to decreasing blood pressure.   Keywords: Non pharmacological, Hypertension, End Stage Renal Disease


Aorta ◽  
2020 ◽  
Vol 08 (02) ◽  
pp. 041-045
Author(s):  
Stavros K. Kakkos ◽  
Chrysanthi P. Papageorgopoulou ◽  
Konstantinos Katsanos ◽  
Peter Zampakis ◽  
Athina Siampalioti ◽  
...  

AbstractA 71-year-old man with end-stage renal disease on hemodialysis presented with bilateral common iliac artery aneurysms diagnosed during the workup of his chronic kidney disease. On computed tomography angiography, common iliac artery aneurysm diameters measured 6.1 cm on the right side and 3.1 cm on the left side. The infrarenal aorta also had a small 3.2-cm aneurysm, but the length from the lowest left renal to the aortic bifurcation was only 6.7 cm, precluding use of most bifurcated endografts. Following an uneventful staged preoperative internal iliac artery embolization, a two-piece D-shaped Altura endograft for the aorta, with bilateral iliac components, landing at the level of the external iliac arteries was successfully performed. Postoperative course was uneventful with no endoleak or endograft migration on computerized tomographic angiography 45 days later, although billowing mimicking an endoleak was evident and will be closely followed.


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